renal/urinary system inflammation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description local accumulation of fluid, plasma proteins, and leukocytes in the renal/urinary system; may involve inflammation of the urethra, urinary bladder, ureters or kidneys (Mammalian Phenotype Ontology, MP_0011762)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011762
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Genes

141 gene mutations causing the renal/urinary system inflammation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACE angiotensin I converting enzyme
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHR aryl hydrocarbon receptor
ALMS1 Alstrom syndrome protein 1
ANK1 ankyrin 1, erythrocytic
APCS amyloid P component, serum
APRT adenine phosphoribosyltransferase
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARID5B AT rich interactive domain 5B (MRF1-like)
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1QA complement component 1, q subcomponent, A chain
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
CCR1 chemokine (C-C motif) receptor 1
CD151 CD151 molecule (Raph blood group)
CD1D CD1d molecule
CD72 CD72 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFH complement factor H
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A5 collagen, type IV, alpha 5
CORO1A coronin, actin binding protein, 1A
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CXCR3 chemokine (C-X-C motif) receptor 3
DCN decorin
DNASE1 deoxyribonuclease I
DTX1 deltex 1, E3 ubiquitin ligase
E2F2 E2F transcription factor 2
EFS embryonal Fyn-associated substrate
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FOXO3 forkhead box O3
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GATA5 GATA binding protein 5
GDNF glial cell derived neurotrophic factor
GLIS2 GLIS family zinc finger 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GOLM1 golgi membrane protein 1
GPR132 G protein-coupled receptor 132
GPX7 glutathione peroxidase 7
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GSTK1 glutathione S-transferase kappa 1
HMOX1 heme oxygenase 1
HR hair growth associated
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IFNG interferon, gamma
IGHM immunoglobulin heavy constant mu
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL12RB2 interleukin 12 receptor, beta 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAMB2 laminin, beta 2 (laminin S)
LAT linker for activation of T cells
LRRK2 leucine-rich repeat kinase 2
LYN LYN proto-oncogene, Src family tyrosine kinase
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MARK2 MAP/microtubule affinity-regulating kinase 2
MDK midkine (neurite growth-promoting factor 2)
MEP1A meprin A, alpha (PABA peptide hydrolase)
MET MET proto-oncogene, receptor tyrosine kinase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MTA2 metastasis associated 1 family, member 2
MTUS1 microtubule associated tumor suppressor 1
MUT methylmalonyl CoA mutase
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFE2L2 nuclear factor, erythroid 2-like 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHP3 nephronophthisis 3 (adolescent)
PDCD1 programmed cell death 1
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PGM3 phosphoglucomutase 3
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKN1 protein kinase N1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POLB polymerase (DNA directed), beta
PRKCD protein kinase C, delta
PSAP prosaposin
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RC3H1 ring finger and CCCH-type domains 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REN renin
RPL22 ribosomal protein L22
SCARA5 scavenger receptor class A, member 5
SCARF1 scavenger receptor class F, member 1
SCTR secretin receptor
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGPL1 sphingosine-1-phosphate lyase 1
SIAE sialic acid acetylesterase
SIRT1 sirtuin 1
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMAD3 SMAD family member 3
SOCS1 suppressor of cytokine signaling 1
SPTA1 spectrin, alpha, erythrocytic 1
SPTB spectrin, beta, erythrocytic
SYK spleen tyrosine kinase
TANK TRAF family member-associated NFKB activator
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLR8 toll-like receptor 8
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNIP1 TNFAIP3 interacting protein 1
TNS1 tensin 1
TNS2 tensin 2
TOP3B topoisomerase (DNA) III beta
TP63 tumor protein p63
TRAF3IP2 TRAF3 interacting protein 2
TREX1 three prime repair exonuclease 1
TROVE2 TROVE domain family, member 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TUSC2 tumor suppressor candidate 2
UNC93B1 unc-93 homolog B1 (C. elegans)
UOX urate oxidase, pseudogene
WAS Wiskott-Aldrich syndrome
WDR83 WD repeat domain 83
WT1 Wilms tumor 1
WWTR1 WW domain containing transcription regulator 1
XDH xanthine dehydrogenase