regulation of erk1 and erk2 cascade Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade. (Gene Ontology, GO_0070372)
External Link http://amigo.geneontology.org/amigo/term/GO:0070372
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Genes

171 genes participating in the regulation of erk1 and erk2 cascade biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACKR3 atypical chemokine receptor 3
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRA1A adrenoceptor alpha 1A
ALOX15 arachidonate 15-lipoxygenase
ANGPT1 angiopoietin 1
ANKRD26 ankyrin repeat domain 26
APIP APAF1 interacting protein
ARHGAP8 Rho GTPase activating protein 8
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMPER BMP binding endothelial regulator
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1QL4 complement component 1, q subcomponent-like 4
C3ORF33 chromosome 3 open reading frame 33
C5AR1 complement component 5a receptor 1
C5AR2 complement component 5a receptor 2
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CCL19 chemokine (C-C motif) ligand 19
CCL21 chemokine (C-C motif) ligand 21
CCL3 chemokine (C-C motif) ligand 3
CCR1 chemokine (C-C motif) receptor 1
CCR7 chemokine (C-C motif) receptor 7
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIB1 calcium and integrin binding 1 (calmyrin)
CNKSR3 CNKSR family member 3
CSF1R colony stimulating factor 1 receptor
CSK c-src tyrosine kinase
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
CYSLTR2 cysteinyl leukotriene receptor 2
DAB2IP DAB2 interacting protein
DCC DCC netrin 1 receptor
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27
DRD2 dopamine receptor D2
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP1 dual specificity phosphatase 1
DUSP26 dual specificity phosphatase 26 (putative)
DUSP3 dual specificity phosphatase 3
DUSP6 dual specificity phosphatase 6
EDNRA endothelin receptor type A
EGFR epidermal growth factor receptor
EPHA2 EPH receptor A2
EPHA7 EPH receptor A7
EPHB1 EPH receptor B1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FFAR4 free fatty acid receptor 4
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF20 fibroblast growth factor 20
FGF21 fibroblast growth factor 21
FGF23 fibroblast growth factor 23
FGF4 fibroblast growth factor 4
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FGG fibrinogen gamma chain
FLCN folliculin
FLT4 fms-related tyrosine kinase 4
FRS2 fibroblast growth factor receptor substrate 2
GAREM GRB2 associated, regulator of MAPK1
GAS6 growth arrest-specific 6
GCG glucagon
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLIPR2 GLI pathogenesis-related 2
GPER1 G protein-coupled estrogen receptor 1
GPR183 G protein-coupled receptor 183
GPR55 G protein-coupled receptor 55
GSTP1 glutathione S-transferase pi 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HRAS Harvey rat sarcoma viral oncogene homolog
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1A interleukin 1, alpha
IL26 interleukin 26
IL6 interleukin 6
ITGB1BP1 integrin beta 1 binding protein 1
KDR kinase insert domain receptor
KLF4 Kruppel-like factor 4 (gut)
LIF leukemia inhibitory factor
LMO3 LIM domain only 3 (rhombotin-like 2)
LYN LYN proto-oncogene, Src family tyrosine kinase
MAPK3 mitogen-activated protein kinase 3
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MT3 metallothionein 3
NDRG2 NDRG family member 2
NDRG4 NDRG family member 4
NEK10 NIMA-related kinase 10
NLRP12 NLR family, pyrin domain containing 12
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NODAL nodal growth differentiation factor
NOX4 NADPH oxidase 4
NPNT nephronectin
NRP1 neuropilin 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OPRM1 opioid receptor, mu 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G5 phospholipase A2, group V
PRKCA protein kinase C, alpha
PRKCDBP protein kinase C, delta binding protein
PRKCZ protein kinase C, zeta
PRKD2 protein kinase D2
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRR protein tyrosine phosphatase, receptor type, R
PYCARD PYD and CARD domain containing
RANBP9 RAN binding protein 9
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RARA retinoic acid receptor, alpha
RGS14 regulator of G-protein signaling 14
RIPK2 receptor-interacting serine-threonine kinase 2
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRAS related RAS viral (r-ras) oncogene homolog
S100A7 S100 calcium binding protein A7
SCIMP SLP adaptor and CSK interacting membrane protein
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STYX serine/threonine/tyrosine interacting protein
SYK spleen tyrosine kinase
TBC1D10C TBC1 domain family, member 10C
TEK TEK tyrosine kinase, endothelial
TFF2 trefoil factor 2
THPO thrombopoietin
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNIP1 TNFAIP3 interacting protein 1
TREM2 triggering receptor expressed on myeloid cells 2
VRK3 vaccinia related kinase 3
WNK2 WNK lysine deficient protein kinase 2