reduced long term depression Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description less than the normal, persistent activity-dependent decrease in synaptic efficacy between neurons, often following slow, weak stimulation of CA1 neurons (Mammalian Phenotype Ontology, MP_0001475)
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31 gene mutations causing the reduced long term depression phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AKAP5 A kinase (PRKA) anchor protein 5
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK4 calcium/calmodulin-dependent protein kinase IV
CD247 CD247 molecule
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CHRM1 cholinergic receptor, muscarinic 1
CNR1 cannabinoid receptor 1 (brain)
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
FOXP2 forkhead box P2
GFAP glial fibrillary acidic protein
GRID2 glutamate receptor, ionotropic, delta 2
GRM1 glutamate receptor, metabotropic 1
GRM2 glutamate receptor, metabotropic 2
KIF17 kinesin family member 17
LAMA2 laminin, alpha 2
LRRC7 leucine rich repeat containing 7
MYO5A myosin VA (heavy chain 12, myoxin)
PINK1 PTEN induced putative kinase 1
PLCB4 phospholipase C, beta 4
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RALBP1 ralA binding protein 1
RAVER1 ribonucleoprotein, PTB-binding 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VGF VGF nerve growth factor inducible
WASF1 WAS protein family, member 1
WWC1 WW and C2 domain containing 1