receptor internalization Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane. (Gene Ontology, GO_0031623)
External Link http://amigo.geneontology.org/amigo/term/GO:0031623
Similar Terms
Downloads & Tools

Genes

41 genes participating in the receptor internalization biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
ADRBK1 adrenergic, beta, receptor kinase 1
ADRBK2 adrenergic, beta, receptor kinase 2
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
CALCR calcitonin receptor
CALCRL calcitonin receptor-like
CAV1 caveolin 1, caveolae protein, 22kDa
CAV3 caveolin 3
CLTC clathrin, heavy chain (Hc)
CNTN2 contactin 2 (axonal)
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
DNM1 dynamin 1
DNM2 dynamin 2
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
EZR ezrin
GRB2 growth factor receptor-bound protein 2
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRK4 G protein-coupled receptor kinase 4
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LMBRD1 LMBR1 domain containing 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
PICALM phosphatidylinositol binding clathrin assembly protein
PLD2 phospholipase D2
RAB31 RAB31, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RAMP3 receptor (G protein-coupled) activity modifying protein 3
SCYL2 SCY1-like 2 (S. cerevisiae)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX1 sorting nexin 1
ULK1 unc-51 like autophagy activating kinase 1