rational Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

90 genes co-occuring with the biological term rational in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACVR1 activin A receptor, type I
BACE1 beta-site APP-cleaving enzyme 1
BCR breakpoint cluster region
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
CA9 carbonic anhydrase IX
CASP6 caspase 6, apoptosis-related cysteine peptidase
CBFB core-binding factor, beta subunit
CD52 CD52 molecule
CDCP1 CUB domain containing protein 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLEC1B C-type lectin domain family 1, member B
CLEC4D C-type lectin domain family 4, member D
CLEC4E C-type lectin domain family 4, member E
CUL5 cullin 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DACH1 dachshund family transcription factor 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DYSF dysferlin
E2F3 E2F transcription factor 3
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ETV6 ets variant 6
EYA4 EYA transcriptional coactivator and phosphatase 4
FGFR2 fibroblast growth factor receptor 2
FKBP5 FK506 binding protein 5
GDNF glial cell derived neurotrophic factor
GJA1 gap junction protein, alpha 1, 43kDa
GPBAR1 G protein-coupled bile acid receptor 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLF hepatic leukemia factor
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IL15 interleukin 15
IL2RA interleukin 2 receptor, alpha
ITK IL2-inducible T-cell kinase
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF1 Kruppel-like factor 1 (erythroid)
KLF4 Kruppel-like factor 4 (gut)
KRAS Kirsten rat sarcoma viral oncogene homolog
LEP leptin
MAP2K1 mitogen-activated protein kinase kinase 1
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MIR126 microRNA 126
MIR191 microRNA 191
MIR217 microRNA 217
MMP10 matrix metallopeptidase 10
MPO myeloperoxidase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYD88 myeloid differentiation primary response 88
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit
NCOA2 nuclear receptor coactivator 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
POR P450 (cytochrome) oxidoreductase
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSD4 pleckstrin and Sec7 domain containing 4
PTEN phosphatase and tensin homolog
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RET ret proto-oncogene
RHOA ras homolog family member A
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RUNX1 runt-related transcription factor 1
SIRT2 sirtuin 2
SIX1 SIX homeobox 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYK spleen tyrosine kinase
TCF3 transcription factor 3
TERT telomerase reverse transcriptase
TFRC transferrin receptor
TNF tumor necrosis factor
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TP53 tumor protein p53
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VEGFA vascular endothelial growth factor A
WEE1 WEE1 G2 checkpoint kinase