ramipril-6792 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ramipril-6792 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGRP agouti related neuropeptide
AIM1L absent in melanoma 1-like
AK1 adenylate kinase 1
ARID5A AT rich interactive domain 5A (MRF1-like)
ATF6B activating transcription factor 6 beta
BAIAP3 BAI1-associated protein 3
BLZF1 basic leucine zipper nuclear factor 1
BTF3P11 basic transcription factor 3 pseudogene 11
BTN2A2 butyrophilin, subfamily 2, member A2
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CCDC71 coiled-coil domain containing 71
CCDC88A coiled-coil domain containing 88A
CD1A CD1a molecule
CD4 CD4 molecule
CD48 CD48 molecule
CD52 CD52 molecule
CDC14B cell division cycle 14B
CEND1 cell cycle exit and neuronal differentiation 1
CFAP45 cilia and flagella associated protein 45
CHKB choline kinase beta
CLCN7 chloride channel, voltage-sensitive 7
CLIP2 CAP-GLY domain containing linker protein 2
COL6A1 collagen, type VI, alpha 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CST4 cystatin S
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DAPK2 death-associated protein kinase 2
DCSTAMP dendrocyte expressed seven transmembrane protein
DCTN1 dynactin 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DYSF dysferlin
EDNRB endothelin receptor type B
ELSPBP1 epididymal sperm binding protein 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FAM214B family with sequence similarity 214, member B
FAM76A family with sequence similarity 76, member A
FGB fibrinogen beta chain
FHL1 four and a half LIM domains 1
FOXN2 forkhead box N2
GADD45G growth arrest and DNA-damage-inducible, gamma
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GP2 glycoprotein 2 (zymogen granule membrane)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIPK2 homeodomain interacting protein kinase 2
HIST1H3I histone cluster 1, H3i
HOXA4 homeobox A4
HPCAL4 hippocalcin like 4
ICA1 islet cell autoantigen 1, 69kDa
IGF2-AS IGF2 antisense RNA
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHMBP2 immunoglobulin mu binding protein 2
IGL immunoglobulin lambda locus
IL1R1 interleukin 1 receptor, type I
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT16 keratin 16, type I
KRT83 keratin 83, type II
KRT85 keratin 85, type II
MED16 mediator complex subunit 16
MOBP myelin-associated oligodendrocyte basic protein
MTMR7 myotubularin related protein 7
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL10 myosin, light chain 10, regulatory
NPTXR neuronal pentraxin receptor
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NXPH4 neurexophilin 4
OR7C1 olfactory receptor, family 7, subfamily C, member 1
OXCT2 3-oxoacid CoA transferase 2
PCDHB13 protocadherin beta 13
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM3 PDZ and LIM domain 3
PKP2 plakophilin 2
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
RGS11 regulator of G-protein signaling 11
SCN1B sodium channel, voltage gated, type I beta subunit
SFRP4 secreted frizzled-related protein 4
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC35E2 solute carrier family 35, member E2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SRRT serrate, RNA effector molecule
ST7L suppression of tumorigenicity 7 like
STAT2 signal transducer and activator of transcription 2, 113kDa
STRA6 stimulated by retinoic acid 6
TBL1Y transducin (beta)-like 1, Y-linked
TLX2 T-cell leukemia homeobox 2
TMCC2 transmembrane and coiled-coil domain family 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TOP3B topoisomerase (DNA) III beta
TRIM29 tripartite motif containing 29
UPK3B uroplakin 3B
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WSCD1 WSC domain containing 1
ZNF37BP zinc finger protein 37B, pseudogene
ZNF528 zinc finger protein 528
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AHDC1 AT hook, DNA binding motif, containing 1
ALPK1 alpha-kinase 1
AMPD2 adenosine monophosphate deaminase 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD40 ankyrin repeat domain 40
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATF3 activating transcription factor 3
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BAHD1 bromo adjacent homology domain containing 1
BBS1 Bardet-Biedl syndrome 1
C11ORF95 chromosome 11 open reading frame 95
C4ORF29 chromosome 4 open reading frame 29
CAPG capping protein (actin filament), gelsolin-like
CBR4 carbonyl reductase 4
CDK3 cyclin-dependent kinase 3
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLDN15 claudin 15
CTAGE9 CTAGE family, member 9
DDIT3 DNA-damage-inducible transcript 3
DPYSL2 dihydropyrimidinase-like 2
ECSIT ECSIT signalling integrator
ELMO3 engulfment and cell motility 3
ERCC4 excision repair cross-complementation group 4
ETAA1 Ewing tumor-associated antigen 1
EXOC2 exocyst complex component 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM188A family with sequence similarity 188, member A
FSD1 fibronectin type III and SPRY domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAMT guanidinoacetate N-methyltransferase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLI3 GLI family zinc finger 3
GMEB1 glucocorticoid modulatory element binding protein 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AJ histone cluster 1, H2aj
HOXC11 homeobox C11
IFI35 interferon-induced protein 35
IFT22 intraflagellar transport 22
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INADL InaD-like (Drosophila)
IPP intracisternal A particle-promoted polypeptide
IRAK4 interleukin-1 receptor-associated kinase 4
JMJD4 jumonji domain containing 4
JUNB jun B proto-oncogene
KAT2A K(lysine) acetyltransferase 2A
KIF16B kinesin family member 16B
KPTN kaptin (actin binding protein)
KRBOX4 KRAB box domain containing 4
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LYPD3 LY6/PLAUR domain containing 3
MAGEH1 melanoma antigen family H1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
NABP2 nucleic acid binding protein 2
NDRG4 NDRG family member 4
NUBPL nucleotide binding protein-like
OSMR oncostatin M receptor
P3H1 prolyl 3-hydroxylase 1
PADI2 peptidyl arginine deiminase, type II
PCDHGB5 protocadherin gamma subfamily B, 5
PCNXL4 pecanex-like 4 (Drosophila)
PDZRN3 PDZ domain containing ring finger 3
PHACTR4 phosphatase and actin regulator 4
PHC1 polyhomeotic homolog 1 (Drosophila)
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
RABL6 RAB, member RAS oncogene family-like 6
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SCAI suppressor of cancer cell invasion
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLIT2 slit homolog 2 (Drosophila)
SMYD5 SMYD family member 5
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STEAP3 STEAP family member 3, metalloreductase
SYT17 synaptotagmin XVII
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC7 transmembrane channel-like 7
TRAPPC2 trafficking protein particle complex 2
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TUBA3C tubulin, alpha 3c
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF227 zinc finger protein 227
ZNF250 zinc finger protein 250
ZNF329 zinc finger protein 329
ZNF394 zinc finger protein 394
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675
ZNF7 zinc finger protein 7
ZNF91 zinc finger protein 91