ramifenazone-6097 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the ramifenazone-6097 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BGN biglycan
BIN1 bridging integrator 1
BMP8A bone morphogenetic protein 8a
BTG2 BTG family, member 2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C10ORF12 chromosome 10 open reading frame 12
CBX2 chromobox homolog 2
CCIN calicin
CDHR2 cadherin-related family member 2
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
COL5A2 collagen, type V, alpha 2
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DEFB126 defensin, beta 126
DENND1C DENN/MADD domain containing 1C
DGCR8 DGCR8 microprocessor complex subunit
DGKB diacylglycerol kinase, beta 90kDa
DIAPH2-AS1 DIAPH2 antisense RNA 1
DST dystonin
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELN elastin
ERO1LB ERO1-like beta (S. cerevisiae)
ETV5 ets variant 5
FADS2 fatty acid desaturase 2
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
GBP2 guanylate binding protein 2, interferon-inducible
GCK glucokinase (hexokinase 4)
GLB1L galactosidase, beta 1-like
GP5 glycoprotein V (platelet)
GRM1 glutamate receptor, metabotropic 1
GSN gelsolin
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H4A histone cluster 1, H4a
HOXA10 homeobox A10
HSF1 heat shock transcription factor 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IL1RN interleukin 1 receptor antagonist
INE1 inactivation escape 1 (non-protein coding)
INSL5 insulin-like 5
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
LGALS9 lectin, galactoside-binding, soluble, 9
LIF leukemia inhibitory factor
LTBP4 latent transforming growth factor beta binding protein 4
MAGEC1 melanoma antigen family C1
MARS methionyl-tRNA synthetase
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MILR1 mast cell immunoglobulin-like receptor 1
MIR622 microRNA 622
MPZ myelin protein zero
MST1 macrophage stimulating 1
MVB12B multivesicular body subunit 12B
MYBPC3 myosin binding protein C, cardiac
NAT6 N-acetyltransferase 6 (GCN5-related)
NFX1 nuclear transcription factor, X-box binding 1
OTUD7B OTU deubiquitinase 7B
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAPPA2 pappalysin 2
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PAX3 paired box 3
PAX8 paired box 8
PCDHB17P protocadherin beta 17 pseudogene
PIP prolactin-induced protein
PPP5C protein phosphatase 5, catalytic subunit
PRAMEF11 PRAME family member 11
PRB4 proline-rich protein BstNI subfamily 4
PRLR prolactin receptor
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPA4 replication protein A4, 30kDa
RUNX1 runt-related transcription factor 1
SCN2B sodium channel, voltage gated, type II beta subunit
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLN sarcolipin
SNTG1 syntrophin, gamma 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAGLN3 transgelin 3
TENM1 teneurin transmembrane protein 1
TIMP3 TIMP metallopeptidase inhibitor 3
TREM1 triggering receptor expressed on myeloid cells 1
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
USP22 ubiquitin specific peptidase 22
VN1R1 vomeronasal 1 receptor 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
YIPF4 Yip1 domain family, member 4
ZBTB48 zinc finger and BTB domain containing 48
ZNF175 zinc finger protein 175
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACVR2B activin A receptor, type IIB
ADM adrenomedullin
AP3M2 adaptor-related protein complex 3, mu 2 subunit
BCAS1 breast carcinoma amplified sequence 1
BCORL1 BCL6 corepressor-like 1
BMP10 bone morphogenetic protein 10
BTBD2 BTB (POZ) domain containing 2
C7ORF43 chromosome 7 open reading frame 43
C8ORF60 chromosome 8 open reading frame 60
CA5BP1 carbonic anhydrase VB pseudogene 1
CBR3 carbonyl reductase 3
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD151 CD151 molecule (Raph blood group)
CDK5 cyclin-dependent kinase 5
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLSPN claspin
CRIP1 cysteine-rich protein 1 (intestinal)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP8 dual specificity phosphatase 8
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ERN1 endoplasmic reticulum to nucleus signaling 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ESRP2 epithelial splicing regulatory protein 2
EXOSC9 exosome component 9
FBXL6 F-box and leucine-rich repeat protein 6
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLS2 glutaminase 2 (liver, mitochondrial)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H4F histone cluster 1, H4f
HIST2H2AA3 histone cluster 2, H2aa3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXB2 homeobox B2
IFI35 interferon-induced protein 35
IFNA14 interferon, alpha 14
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL22 interleukin 22
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KLHL25 kelch-like family member 25
KRT24 keratin 24, type I
LENEP lens epithelial protein
LIN7A lin-7 homolog A (C. elegans)
LPXN leupaxin
LRP5L low density lipoprotein receptor-related protein 5-like
LY6D lymphocyte antigen 6 complex, locus D
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYRM2 LYR motif containing 2
LYRM9 LYR motif containing 9
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MGC12488
MYOZ3 myozenin 3
NABP2 nucleic acid binding protein 2
NHLRC2 NHL repeat containing 2
NKRF NFKB repressing factor
OTUD3 OTU deubiquitinase 3
PDE12 phosphodiesterase 12
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLA2G10 phospholipase A2, group X
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PORCN porcupine homolog (Drosophila)
PPARG peroxisome proliferator-activated receptor gamma
RAB40C RAB40C, member RAS oncogene family
RFXAP regulatory factor X-associated protein
RHOC ras homolog family member C
RPAP1 RNA polymerase II associated protein 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLPI secretory leukocyte peptidase inhibitor
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STEAP1 six transmembrane epithelial antigen of the prostate 1
STRA6 stimulated by retinoic acid 6
SUN2 Sad1 and UNC84 domain containing 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM180 transmembrane protein 180
TMEM19 transmembrane protein 19
TMEM242 transmembrane protein 242
TNS2 tensin 2
UNC119 unc-119 homolog (C. elegans)
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
XDH xanthine dehydrogenase
YIF1A Yip1 interacting factor homolog A (S. cerevisiae)
ZNF219 zinc finger protein 219
ZNF428 zinc finger protein 428
ZNF675 zinc finger protein 675