ramifenazone-5879 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

192 genes differentially expressed following the ramifenazone-5879 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAM22 ADAM metallopeptidase domain 22
ADAM23 ADAM metallopeptidase domain 23
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANKRD6 ankyrin repeat domain 6
ARHGAP26 Rho GTPase activating protein 26
BEND5 BEN domain containing 5
BEX4 brain expressed, X-linked 4
BTG2 BTG family, member 2
C3 complement component 3
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASKIN2 CASK interacting protein 2
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC9 coiled-coil domain containing 9
CCNJL cyclin J-like
CCNO cyclin O
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD248 CD248 molecule, endosialin
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEL carboxyl ester lipase
CLCN4 chloride channel, voltage-sensitive 4
COL2A1 collagen, type II, alpha 1
COL3A1 collagen, type III, alpha 1
CTSF cathepsin F
CUZD1 CUB and zona pellucida-like domains 1
DCT dopachrome tautomerase
DLX4 distal-less homeobox 4
DNAL4 dynein, axonemal, light chain 4
ELL2 elongation factor, RNA polymerase II, 2
EML2 echinoderm microtubule associated protein like 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM65A family with sequence similarity 65, member A
FBXO40 F-box protein 40
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GDAP1 ganglioside induced differentiation associated protein 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLS2 glutaminase 2 (liver, mitochondrial)
GLUL glutamate-ammonia ligase
GNS glucosamine (N-acetyl)-6-sulfatase
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
ICOSLG inducible T-cell co-stimulator ligand
IFT27 intraflagellar transport 27
IL27RA interleukin 27 receptor, alpha
KHSRP KH-type splicing regulatory protein
KIAA0922 KIAA0922
KRIT1 KRIT1, ankyrin repeat containing
LOC729164 hCG1732469
MAP2K2 mitogen-activated protein kinase kinase 2
MAP7 microtubule-associated protein 7
METTL7A methyltransferase like 7A
MT1F metallothionein 1F
MXD4 MAX dimerization protein 4
MYH14 myosin, heavy chain 14, non-muscle
NDNF neuron-derived neurotrophic factor
NIPAL2 NIPA-like domain containing 2
NT5M 5',3'-nucleotidase, mitochondrial
NTSR1 neurotensin receptor 1 (high affinity)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCDHGA10 protocadherin gamma subfamily A, 10
PLXNA2 plexin A2
PRAMEF11 PRAME family member 11
PRKCH protein kinase C, eta
PROSER1 proline and serine rich 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN21 protein tyrosine phosphatase, non-receptor type 21
QKI QKI, KH domain containing, RNA binding
RAB5C RAB5C, member RAS oncogene family
RANBP1 RAN binding protein 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RECQL5 RecQ protein-like 5
RHOBTB2 Rho-related BTB domain containing 2
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPL10 ribosomal protein L10
SAFB scaffold attachment factor B
SARM1 sterile alpha and TIR motif containing 1
SCARB2 scavenger receptor class B, member 2
SF3A1 splicing factor 3a, subunit 1, 120kDa
SPTBN1 spectrin, beta, non-erythrocytic 1
STAC SH3 and cysteine rich domain
STK4 serine/threonine kinase 4
STXBP6 syntaxin binding protein 6 (amisyn)
SULT4A1 sulfotransferase family 4A, member 1
TACSTD2 tumor-associated calcium signal transducer 2
TCP11L1 t-complex 11, testis-specific-like 1
TFR2 transferrin receptor 2
TIMELESS timeless circadian clock
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM231 transmembrane protein 231
TNPO3 transportin 3
UTRN utrophin
VEGFA vascular endothelial growth factor A
ZC3H7B zinc finger CCCH-type containing 7B
ZNF358 zinc finger protein 358
ZNF440 zinc finger protein 440
ZNF75D zinc finger protein 75D

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADAM15 ADAM metallopeptidase domain 15
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOL6 apolipoprotein L, 6
APOLD1 apolipoprotein L domain containing 1
ATAD3A ATPase family, AAA domain containing 3A
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
AXIN1 axin 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C4ORF29 chromosome 4 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
CCNT1 cyclin T1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CLSPN claspin
CRELD1 cysteine-rich with EGF-like domains 1
CRIP2 cysteine-rich protein 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
ECM1 extracellular matrix protein 1
EDC3 enhancer of mRNA decapping 3
EFNA3 ephrin-A3
EGLN2 egl-9 family hypoxia-inducible factor 2
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXC1 forkhead box C1
GMIP GEM interacting protein
GOLGA8B golgin A8 family, member B
GPATCH3 G patch domain containing 3
GPR3 G protein-coupled receptor 3
GRPR gastrin-releasing peptide receptor
HAMP hepcidin antimicrobial peptide
HIST1H2BI histone cluster 1, H2bi
HIST1H3B histone cluster 1, H3b
HLX H2.0-like homeobox
HOXB9 homeobox B9
IFNA14 interferon, alpha 14
IFT22 intraflagellar transport 22
IL4R interleukin 4 receptor
INCENP inner centromere protein antigens 135/155kDa
IRAK4 interleukin-1 receptor-associated kinase 4
IREB2 iron-responsive element binding protein 2
IRF2 interferon regulatory factor 2
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCTD15 potassium channel tetramerization domain containing 15
KIAA1551 KIAA1551
KRT31 keratin 31, type I
LRRC15 leucine rich repeat containing 15
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC6 leucine rich repeat containing 6
LYPD3 LY6/PLAUR domain containing 3
MAN2B2 mannosidase, alpha, class 2B, member 2
MBIP MAP3K12 binding inhibitory protein 1
MFSD11 major facilitator superfamily domain containing 11
NAG18 NAG18 mRNA
NQO2 NAD(P)H dehydrogenase, quinone 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PDGFRL platelet-derived growth factor receptor-like
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PMCH pro-melanin-concentrating hormone
PNRC1 proline-rich nuclear receptor coactivator 1
PPCDC phosphopantothenoylcysteine decarboxylase
RNF121 ring finger protein 121
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPAP2 RNA polymerase II associated protein 2
RPL10L ribosomal protein L10-like
RUSC2 RUN and SH3 domain containing 2
SCN1B sodium channel, voltage gated, type I beta subunit
SECISBP2 SECIS binding protein 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SIX1 SIX homeobox 1
SLC25A40 solute carrier family 25, member 40
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SNORA21 small nucleolar RNA, H/ACA box 21
SPATA7 spermatogenesis associated 7
SREK1IP1 SREK1-interacting protein 1
SYTL2 synaptotagmin-like 2
TAGLN3 transgelin 3
TBL3 transducin (beta)-like 3
TMEM62 transmembrane protein 62
TMOD3 tropomodulin 3 (ubiquitous)
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TUBA3C tubulin, alpha 3c
WDR18 WD repeat domain 18
ZNF197 zinc finger protein 197
ZNF263 zinc finger protein 263
ZNF276 zinc finger protein 276
ZNF324 zinc finger protein 324
ZNF862 zinc finger protein 862