quinpirole-3539 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the quinpirole-3539 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABHD2 abhydrolase domain containing 2
ABLIM3 actin binding LIM protein family, member 3
ADAM17 ADAM metallopeptidase domain 17
ADGRE1 adhesion G protein-coupled receptor E1
AJAP1 adherens junctions associated protein 1
AKAP8L A kinase (PRKA) anchor protein 8-like
AKT1 v-akt murine thymoma viral oncogene homolog 1
APOM apolipoprotein M
ATF6B activating transcription factor 6 beta
B9D1 B9 protein domain 1
BHLHE41 basic helix-loop-helix family, member e41
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CCDC64 coiled-coil domain containing 64
CD79A CD79a molecule, immunoglobulin-associated alpha
CDC25A cell division cycle 25A
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CRIP1 cysteine-rich protein 1 (intestinal)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DCN decorin
DEPDC5 DEP domain containing 5
DICER1 dicer 1, ribonuclease type III
DYSF dysferlin
EFS embryonal Fyn-associated substrate
EGFR epidermal growth factor receptor
ELOVL2 ELOVL fatty acid elongase 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FGFR1 fibroblast growth factor receptor 1
FOLH1B folate hydrolase 1B
GK glycerol kinase
GPATCH4 G patch domain containing 4
GSTM5 glutathione S-transferase mu 5
GYG2 glycogenin 2
HIST1H3B histone cluster 1, H3b
HLA-G major histocompatibility complex, class I, G
IGL immunoglobulin lambda locus
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL2RB interleukin 2 receptor, beta
KANSL3 KAT8 regulatory NSL complex subunit 3
KLHL22 kelch-like family member 22
KLK15 kallikrein-related peptidase 15
LAMP3 lysosomal-associated membrane protein 3
LINC00597 long intergenic non-protein coding RNA 597
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MATN1 matrilin 1, cartilage matrix protein
MBD3 methyl-CpG binding domain protein 3
MT1F metallothionein 1F
MTMR3 myotubularin related protein 3
NDRG2 NDRG family member 2
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NRSN2 neurensin 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OGFR opioid growth factor receptor
PCDHB3 protocadherin beta 3
PGBD5 piggyBac transposable element derived 5
PKNOX2 PBX/knotted 1 homeobox 2
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM16 PR domain containing 16
PSEN2 presenilin 2
PSG9 pregnancy specific beta-1-glycoprotein 9
PTPRF protein tyrosine phosphatase, receptor type, F
PXN paxillin
QTRT1 queuine tRNA-ribosyltransferase 1
RANBP3 RAN binding protein 3
RGS2 regulator of G-protein signaling 2
RNF39 ring finger protein 39
RPS2 ribosomal protein S2
RPS3A ribosomal protein S3A
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SIRT4 sirtuin 4
SLA Src-like-adaptor
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNTA1 syntrophin, alpha 1
SOX4 SRY (sex determining region Y)-box 4
SPON2 spondin 2, extracellular matrix protein
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
STC1 stanniocalcin 1
STOML1 stomatin (EPB72)-like 1
SYNC syncoilin, intermediate filament protein
TCF3 transcription factor 3
TMEM259 transmembrane protein 259
TNS2 tensin 2
TOP3B topoisomerase (DNA) III beta
TPMT thiopurine S-methyltransferase
VARS valyl-tRNA synthetase
ZNF609 zinc finger protein 609
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AMT aminomethyltransferase
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BTF3P12 basic transcription factor 3 pseudogene 12
C10ORF95 chromosome 10 open reading frame 95
C2ORF27A chromosome 2 open reading frame 27A
C4ORF29 chromosome 4 open reading frame 29
C5AR2 complement component 5a receptor 2
CCDC121 coiled-coil domain containing 121
CLGN calmegin
CLSTN2 calsyntenin 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CXADR coxsackie virus and adenovirus receptor
CXCR2 chemokine (C-X-C motif) receptor 2
DAGLA diacylglycerol lipase, alpha
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EFNA3 ephrin-A3
EN2 engrailed homeobox 2
ERCC4 excision repair cross-complementation group 4
ERCC6 excision repair cross-complementation group 6
FAM46C family with sequence similarity 46, member C
FBXL2 F-box and leucine-rich repeat protein 2
FER fer (fps/fes related) tyrosine kinase
FLCN folliculin
FLNC filamin C, gamma
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BO histone cluster 1, H2bo
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF1 interferon regulatory factor 1
KDM5C lysine (K)-specific demethylase 5C
KIAA0894 KIAA0894 protein
LARP6 La ribonucleoprotein domain family, member 6
LOC390998 ribosomal protein L10 pseudogene
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LYRM9 LYR motif containing 9
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBTD1 mbt domain containing 1
MGC12488
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MRPL52 mitochondrial ribosomal protein L52
MRPS18C mitochondrial ribosomal protein S18C
NCALD neurocalcin delta
NNAT neuronatin
NPFFR1 neuropeptide FF receptor 1
NPTX1 neuronal pentraxin I
NT5DC3 5'-nucleotidase domain containing 3
OCLM oculomedin
ONECUT2 one cut homeobox 2
PADI1 peptidyl arginine deiminase, type I
PDIA3 protein disulfide isomerase family A, member 3
PLA2G3 phospholipase A2, group III
PTPN14 protein tyrosine phosphatase, non-receptor type 14
QPCTL glutaminyl-peptide cyclotransferase-like
QSER1 glutamine and serine rich 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
ROM1 retinal outer segment membrane protein 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RUSC2 RUN and SH3 domain containing 2
SAYSD1 SAYSVFN motif domain containing 1
SCAI suppressor of cancer cell invasion
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SKI SKI proto-oncogene
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMIM14 small integral membrane protein 14
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAOK1 TAO kinase 1
TMEM53 transmembrane protein 53
TMLHE trimethyllysine hydroxylase, epsilon
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
VASH1 vasohibin 1
VEGFB vascular endothelial growth factor B
VEZT vezatin, adherens junctions transmembrane protein
XK X-linked Kx blood group
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB6 zinc finger and BTB domain containing 6
ZNF10 zinc finger protein 10
ZNF324 zinc finger protein 324
ZNF573 zinc finger protein 573
ZNF652 zinc finger protein 652