quinidine-6267 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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192 genes differentially expressed following the quinidine-6267 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACVR1B activin A receptor, type IB
ADGRG2 adhesion G protein-coupled receptor G2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AHI1 Abelson helper integration site 1
ANGEL2 angel homolog 2 (Drosophila)
APP amyloid beta (A4) precursor protein
ATF7 activating transcription factor 7
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BMP4 bone morphogenetic protein 4
BTD biotinidase
CAPN10 calpain 10
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDK9 cyclin-dependent kinase 9
CHMP6 charged multivesicular body protein 6
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
CPD carboxypeptidase D
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DMC1 DNA meiotic recombinase 1
DUSP4 dual specificity phosphatase 4
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EML3 echinoderm microtubule associated protein like 3
ERN1 endoplasmic reticulum to nucleus signaling 1
FGB fibrinogen beta chain
FOXI1 forkhead box I1
GAS2 growth arrest-specific 2
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR107 G protein-coupled receptor 107
GREB1 growth regulation by estrogen in breast cancer 1
GRIK5 glutamate receptor, ionotropic, kainate 5
GSTCD glutathione S-transferase, C-terminal domain containing
GSTP1 glutathione S-transferase pi 1
HAUS6 HAUS augmin-like complex, subunit 6
HLA-B major histocompatibility complex, class I, B
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMOX1 heme oxygenase 1
IGHM immunoglobulin heavy constant mu
IQCE IQ motif containing E
IRS2 insulin receptor substrate 2
KAT8 K(lysine) acetyltransferase 8
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLF9 Kruppel-like factor 9
LPIN2 lipin 2
MANBA mannosidase, beta A, lysosomal
MAP2K2 mitogen-activated protein kinase kinase 2
MFAP3L microfibrillar-associated protein 3-like
MTCP1 mature T-cell proliferation 1
NCOA2 nuclear receptor coactivator 2
NEK9 NIMA-related kinase 9
NKX2-5 NK2 homeobox 5
NPFFR1 neuropeptide FF receptor 1
OVOL1 ovo-like zinc finger 1
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHB3 protocadherin beta 3
PCDHGA3 protocadherin gamma subfamily A, 3
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPT2 palmitoyl-protein thioesterase 2
PRB1 proline-rich protein BstNI subfamily 1
QKI QKI, KH domain containing, RNA binding
RASAL2 RAS protein activator like 2
RCAN1 regulator of calcineurin 1
RNMT RNA (guanine-7-) methyltransferase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPGR retinitis pigmentosa GTPase regulator
SARM1 sterile alpha and TIR motif containing 1
SENP6 SUMO1/sentrin specific peptidase 6
SETD8 SET domain containing (lysine methyltransferase) 8
SFXN3 sideroflexin 3
SKA1 spindle and kinetochore associated complex subunit 1
SLC25A44 solute carrier family 25, member 44
SMTN smoothelin
SRSF8 serine/arginine-rich splicing factor 8
STK4 serine/threonine kinase 4
SUMO1 small ubiquitin-like modifier 1
TAZ tafazzin
TRA T cell receptor alpha locus
TRAM2 translocation associated membrane protein 2
TSPAN1 tetraspanin 1
UBE3B ubiquitin protein ligase E3B
UTRN utrophin
VAC14 Vac14 homolog (S. cerevisiae)
ZFP36L1 ZFP36 ring finger protein-like 1
ZMYND8 zinc finger, MYND-type containing 8
ZNF117 zinc finger protein 117
ZNF329 zinc finger protein 329
ZNF34 zinc finger protein 34
ZNF701 zinc finger protein 701

decreased expression

Symbol Name
ACTL8 actin-like 8
ALAS1 5'-aminolevulinate synthase 1
ANKRD40 ankyrin repeat domain 40
ANXA2P3 annexin A2 pseudogene 3
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
AXIN1 axin 1
BAHD1 bromo adjacent homology domain containing 1
C11ORF80 chromosome 11 open reading frame 80
C17ORF80 chromosome 17 open reading frame 80
C1ORF115 chromosome 1 open reading frame 115
CCDC88C coiled-coil domain containing 88C
CDKL3 cyclin-dependent kinase-like 3
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CPPED1 calcineurin-like phosphoesterase domain containing 1
CROT carnitine O-octanoyltransferase
DEAF1 DEAF1 transcription factor
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DSPP dentin sialophosphoprotein
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
EVPL envoplakin
FAM114A2 family with sequence similarity 114, member A2
FBXW12 F-box and WD repeat domain containing 12
FKBP10 FK506 binding protein 10, 65 kDa
FKBP14 FK506 binding protein 14, 22 kDa
FPGS folylpolyglutamate synthase
GID4 GID complex subunit 4
GLS2 glutaminase 2 (liver, mitochondrial)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GOLGA8B golgin A8 family, member B
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HIST1H1D histone cluster 1, H1d
HIST1H2AM histone cluster 1, H2am
HIST1H2BC histone cluster 1, H2bc
HOXC13 homeobox C13
IGSF1 immunoglobulin superfamily, member 1
IMPACT impact RWD domain protein
INO80D INO80 complex subunit D
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRAK4 interleukin-1 receptor-associated kinase 4
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KDM5C lysine (K)-specific demethylase 5C
KIAA0125 KIAA0125
KRI1 KRI1 homolog (S. cerevisiae)
LAMA3 laminin, alpha 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPK3 mitogen-activated protein kinase 3
MRPL44 mitochondrial ribosomal protein L44
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MT1H metallothionein 1H
NOL6 nucleolar protein 6 (RNA-associated)
NPIPB15 nuclear pore complex interacting protein family, member B15
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OLFML3 olfactomedin-like 3
P3H1 prolyl 3-hydroxylase 1
PARP4 poly (ADP-ribose) polymerase family, member 4
PDGFRL platelet-derived growth factor receptor-like
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHACTR4 phosphatase and actin regulator 4
PHLDA3 pleckstrin homology-like domain, family A, member 3
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PPAN peter pan homolog (Drosophila)
PYCRL pyrroline-5-carboxylate reductase-like
QTRT1 queuine tRNA-ribosyltransferase 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RBBP5 retinoblastoma binding protein 5
RBM38 RNA binding motif protein 38
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
SIDT1 SID1 transmembrane family, member 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIRT6 sirtuin 6
SMA4 glucuronidase, beta pseudogene
SMR3A submaxillary gland androgen regulated protein 3A
SPHK1 sphingosine kinase 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TDRD1 tudor domain containing 1
TFRC transferrin receptor
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMEM180 transmembrane protein 180
TRAPPC2 trafficking protein particle complex 2
TTC23 tetratricopeptide repeat domain 23
UBXN6 UBX domain protein 6
WLS wntless Wnt ligand secretion mediator
XAB2 XPA binding protein 2
ZBTB3 zinc finger and BTB domain containing 3
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF205 zinc finger protein 205
ZNF442 zinc finger protein 442
ZNF669 zinc finger protein 669
ZNF770 zinc finger protein 770