pulmonary valve disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

150 genes co-occuring with the disease pulmonary valve disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PTPN11 protein tyrosine phosphatase, non-receptor type 11 2.01796
SOS1 son of sevenless homolog 1 (Drosophila) 1.56134
JAG1 jagged 1 1.45441
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 1.39433
TBX1 T-box 1 1.35071
GATA4 GATA binding protein 4 1.21782
MAP2K2 mitogen-activated protein kinase kinase 2 1.21305
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 1.13205
PDLIM1 PDZ and LIM domain 1 1.1173
COL5A3 collagen, type V, alpha 3 1.11183
ELN elastin 1.08412
MAP2K1 mitogen-activated protein kinase kinase 1 0.961634
HIRA histone cell cycle regulator 0.958287
CLTCL1 clathrin, heavy chain-like 1 0.956196
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 0.952856
TBX5 T-box 5 0.930414
BLVRA biliverdin reductase A 0.895
C1D C1D nuclear receptor corepressor 0.889668
ZNF74 zinc finger protein 74 0.852811
NOTCH1 notch 1 0.841344
HRAS Harvey rat sarcoma viral oncogene homolog 0.837246
KLF10 Kruppel-like factor 10 0.816334
MECOM MDS1 and EVI1 complex locus 0.784755
YME1L1 YME1-like 1 ATPase 0.763086
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 0.762678
ACKR3 atypical chemokine receptor 3 0.754527
EHD1 EH-domain containing 1 0.737865
HAND2 heart and neural crest derivatives expressed 2 0.73746
RFX6 regulatory factor X, 6 0.736243
PTER phosphotriesterase related 0.71925
NF1 neurofibromin 1 0.703536
LEFTY1 left-right determination factor 1 0.702732
CROCC ciliary rootlet coiled-coil, rootletin 0.693098
SLN sarcolipin 0.675909
MYL12B myosin, light chain 12B, regulatory 0.660008
GIN1 gypsy retrotransposon integrase 1 0.624927
GAB1 GRB2-associated binding protein 1 0.623359
CNTN3 contactin 3 (plasmacytoma associated) 0.597961
CPB1 carboxypeptidase B1 (tissue) 0.594843
CNTN4 contactin 4 0.588612
MSX2 msh homeobox 2 0.578106
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.577716
ZFPM2 zinc finger protein, FOG family member 2 0.574605
IGLV5-48 immunoglobulin lambda variable 5-48 (non-functional) 0.549747
PTCH1 patched 1 0.545481
COL5A2 collagen, type V, alpha 2 0.543542
ADD3 adducin 3 (gamma) 0.536183
GGCX gamma-glutamyl carboxylase 0.529222
HAND1 heart and neural crest derivatives expressed 1 0.521502
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.518034
KLHL17 kelch-like family member 17 0.496557
PTF1A pancreas specific transcription factor, 1a 0.494648
LEMD3 LEM domain containing 3 0.487407
PTCH2 patched 2 0.483985
SPRED1 sprouty-related, EVH1 domain containing 1 0.478668
CLIC1 chloride intracellular channel 1 0.475255
RERE arginine-glutamic acid dipeptide (RE) repeats 0.468441
INSC inscuteable homolog (Drosophila) 0.46655
TRIM25 tripartite motif containing 25 0.464283
PLN phospholamban 0.452962
COL5A1 collagen, type V, alpha 1 0.439034
NPPA natriuretic peptide A 0.437154
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.436026
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.435651
CXCL6 chemokine (C-X-C motif) ligand 6 0.407919
TNXB tenascin XB 0.403811
ELOVL6 ELOVL fatty acid elongase 6 0.398216
PDZK1IP1 PDZK1 interacting protein 1 0.397843
TNXA tenascin XA (pseudogene) 0.396353
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.387423
TBX3 T-box 3 0.378885
DHDH dihydrodiol dehydrogenase (dimeric) 0.371477
BCO1 beta-carotene oxygenase 1 0.371107
FMN1 formin 1 0.370737
COL6A2 collagen, type VI, alpha 2 0.365193
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.361133
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 0.359657
BRAF B-Raf proto-oncogene, serine/threonine kinase 0.35892
GRHL1 grainyhead-like 1 (Drosophila) 0.357077
ETV3 ets variant 3 0.355604
PRB3 proline-rich protein BstNI subfamily 3 0.354499
HBA2 hemoglobin, alpha 2 0.353763
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.348246
ERAS ES cell expressed Ras 0.346042
GRB2 growth factor receptor-bound protein 2 0.342006
CMA1 chymase 1, mast cell 0.341272
C6ORF25 chromosome 6 open reading frame 25 0.339806
ANGPT2 angiopoietin 2 0.33944
CYGB cytoglobin 0.339073
FMOD fibromodulin 0.336876
NKX2-5 NK2 homeobox 5 0.335412
GATA6 GATA binding protein 6 0.324823
PMM2 phosphomannomutase 2 0.321909
VWF von Willebrand factor 0.321181
STAB2 stabilin 2 0.316092
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.31029
NPPB natriuretic peptide B 0.309566
REN renin 0.298371
HMGA2 high mobility group AT-hook 2 0.298371
LATS2 large tumor suppressor kinase 2 0.287235
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.278654
IGFBP3 insulin-like growth factor binding protein 3 0.278297
JAG2 jagged 2 0.276514
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.269398
BMPR1A bone morphogenetic protein receptor, type IA 0.258064
SFRP2 secreted frizzled-related protein 2 0.25207
ANXA7 annexin A7 0.251366
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.251015
WIPF2 WAS/WASL interacting protein family, member 2 0.248203
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.246098
CXCL16 chemokine (C-X-C motif) ligand 16 0.243645
MGP matrix Gla protein 0.243645
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.241196
PLIN1 perilipin 1 0.240497
BANF1 barrier to autointegration factor 1 0.240148
RER1 retention in endoplasmic reticulum sorting receptor 1 0.240148
RYR2 ryanodine receptor 2 (cardiac) 0.238054
FOXC1 forkhead box C1 0.228679
CYLD cylindromatosis (turban tumor syndrome) 0.221108
ALB albumin 0.212945
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.212608
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 0.209583
POR P450 (cytochrome) oxidoreductase 0.20658
COL3A1 collagen, type III, alpha 1 0.205254
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.204593
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.202946
MSX1 msh homeobox 1 0.201635
LUM lumican 0.192657
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.177029
ACE angiotensin I converting enzyme 0.175947
KRAS Kirsten rat sarcoma viral oncogene homolog 0.174617
FLT4 fms-related tyrosine kinase 4 0.173057
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.162908
EPHA2 EPH receptor A2 0.160761
HBA1 hemoglobin, alpha 1 0.144212
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.143363
PPT1 palmitoyl-protein thioesterase 1 0.143222
MLX MLX, MAX dimerization protein 0.143091
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.143082
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.143051
CA2 carbonic anhydrase II 0.142463
MMD monocyte to macrophage differentiation-associated 0.142043
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.141937
PRRC2A proline-rich coiled-coil 2A 0.141709
MEFV Mediterranean fever 0.141628
FGFR1 fibroblast growth factor receptor 1 0.140584
CTGF connective tissue growth factor 0.139753
FLT1 fms-related tyrosine kinase 1 0.135755
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.135257
TNNI3 troponin I type 3 (cardiac) 0.13475