pulmonary tuberculosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis. (Human Disease Ontology, DOID_2957)
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Genes

249 genes co-occuring with the disease pulmonary tuberculosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CD4 CD4 molecule 2.02884
PTBP2 polypyrimidine tract binding protein 2 1.5538
ADA adenosine deaminase 1.5423
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 1.49394
PTBP1 polypyrimidine tract binding protein 1 1.43639
SP110 SP110 nuclear body protein 1.39302
CRP C-reactive protein, pentraxin-related 1.34156
ALB albumin 1.29309
CD79A CD79a molecule, immunoglobulin-associated alpha 1.24385
TNF tumor necrosis factor 1.23082
HP haptoglobin 1.17121
IL2RA interleukin 2 receptor, alpha 1.16606
HPR haptoglobin-related protein 1.16435
POMC proopiomelanocortin 1.12783
TMSB10 thymosin beta 10 1.09377
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.08412
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 1.04504
IL2 interleukin 2 1.0303
HAUS6 HAUS augmin-like complex, subunit 6 1.02102
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.01047
TLR2 toll-like receptor 2 1.00288
IFNGR1 interferon gamma receptor 1 0.998236
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 0.990644
IFNG interferon, gamma 0.937459
TBP TATA box binding protein 0.925865
LYZ lysozyme 0.914315
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 0.885569
CCL2 chemokine (C-C motif) ligand 2 0.883521
ESX1 ESX homeobox 1 0.856087
IL1B interleukin 1, beta 0.851992
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.848307
IL10 interleukin 10 0.848307
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.846669
CP ceruloplasmin (ferroxidase) 0.826178
IL4 interleukin 4 0.816334
FLNC filamin C, gamma 0.801974
CXCL10 chemokine (C-X-C motif) ligand 10 0.793771
FAM135B family with sequence similarity 135, member B 0.781888
TGFB1 transforming growth factor, beta 1 0.773705
HLA-A major histocompatibility complex, class I, A 0.763902
CD209 CD209 molecule 0.761454
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.759416
HLA-C major histocompatibility complex, class I, C 0.756564
TLR6 toll-like receptor 6 0.753306
PGM1 phosphoglucomutase 1 0.741517
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.734217
IL12B interleukin 12B 0.732596
KIZ kizuna centrosomal protein 0.725311
IL12RB1 interleukin 12 receptor, beta 1 0.697911
TLR1 toll-like receptor 1 0.696707
REXO2 RNA exonuclease 2 0.682693
CXCL8 chemokine (C-X-C motif) ligand 8 0.681495
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.674713
IL18 interleukin 18 0.67312
CCL3 chemokine (C-C motif) ligand 3 0.649718
RPL13 ribosomal protein L13 0.641039
ANO9 anoctamin 9 0.637102
TF transferrin 0.626103
NELFCD negative elongation factor complex member C/D 0.622183
OR5K1 olfactory receptor, family 5, subfamily K, member 1 0.619834
GNLY granulysin 0.61866
CCL13 chemokine (C-C motif) ligand 13 0.608494
DYNLRB2 dynein, light chain, roadblock-type 2 0.606933
PRF1 perforin 1 (pore forming protein) 0.593285
TLR4 toll-like receptor 4 0.573439
ALPPL2 alkaline phosphatase, placental-like 2 0.570329
ALPP alkaline phosphatase, placental 0.569941
ALPL alkaline phosphatase, liver/bone/kidney 0.569552
MYBBP1A MYB binding protein (P160) 1a 0.566054
CCL5 chemokine (C-C motif) ligand 5 0.566054
ACP1 acid phosphatase 1, soluble 0.565277
COX6CP4 cytochrome c oxidase subunit VIc pseudogene 4 0.564889
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.553627
IGH immunoglobulin heavy locus 0.542767
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific 0.539667
FTH1 ferritin, heavy polypeptide 1 0.536957
AVPR2 arginine vasopressin receptor 2 0.528063
F2 coagulation factor II (thrombin) 0.52729
OPN5 opsin 5 0.524588
GLO1 glyoxalase I 0.51611
LTA lymphotoxin alpha 0.514956
RSU1 Ras suppressor protein 1 0.511496
CTSW cathepsin W 0.509959
FTL ferritin, light polypeptide 0.504973
MMP23B matrix metallopeptidase 23B 0.499997
IL6 interleukin 6 0.495029
SFTPA2 surfactant protein A2 0.493885
BTNL2 butyrophilin-like 2 0.490835
L3MBTL1 l(3)mbt-like 1 (Drosophila) 0.487407
IL31RA interleukin 31 receptor A 0.484364
INS insulin 0.484364
CXCL9 chemokine (C-X-C motif) ligand 9 0.483985
MRC1 mannose receptor, C type 1 0.479807
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.479047
MIER1 mesoderm induction early response 1, transcriptional regulator 0.47374
EREG epiregulin 0.466172
CXCR2 chemokine (C-X-C motif) receptor 2 0.465794
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.462016
B2M beta-2-microglobulin 0.459373
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.457864
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.452585
CD27 CD27 molecule 0.451078
ALYREF Aly/REF export factor 0.449571
JTB jumping translocation breakpoint 0.447687
GPR148 G protein-coupled receptor 148 0.443923
FOXP3 forkhead box P3 0.443923
TREM1 triggering receptor expressed on myeloid cells 1 0.442795
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.440538
NCAM1 neural cell adhesion molecule 1 0.43941
MBD1 methyl-CpG binding domain protein 1 0.43753
HRC histidine rich calcium binding protein 0.42739
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 0.426265
LTF lactotransferrin 0.423265
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.42289
TOX thymocyte selection-associated high mobility group box 0.42289
EDNRA endothelin receptor type A 0.413527
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.411657
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.410909
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.407545
TES testin LIM domain protein 0.407172
ERP44 endoplasmic reticulum protein 44 0.406051
CD38 CD38 molecule 0.403811
CFP complement factor properdin 0.399334
TLR8 toll-like receptor 8 0.398962
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.398216
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.398216
SRSF4 serine/arginine-rich splicing factor 4 0.39598
FLNA filamin A, alpha 0.393746
FRRS1 ferric-chelate reductase 1 0.392629
NOS2 nitric oxide synthase 2, inducible 0.388166
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.387051
KLRF1 killer cell lectin-like receptor subfamily F, member 1 0.385565
BANF1 barrier to autointegration factor 1 0.384822
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 0.384079
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 0.381481
ZFP64 ZFP64 zinc finger protein 0.380368
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 0.379626
RNF139 ring finger protein 139 0.378143
SFTPA1 surfactant protein A1 0.377402
MUC1 mucin 1, cell surface associated 0.371477
NUBPL nucleotide binding protein-like 0.370368
WDFY2 WD repeat and FYVE domain containing 2 0.369997
ACE angiotensin I converting enzyme 0.369258
IL17A interleukin 17A 0.366671
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.365932
MYD88 myeloid differentiation primary response 88 0.364824
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.360395
CAMP cathelicidin antimicrobial peptide 0.357814
HLX H2.0-like homeobox 0.355235
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.351923
IL1A interleukin 1, alpha 0.350452
G6PD glucose-6-phosphate dehydrogenase 0.350084
LEP leptin 0.344207
TUB tubby bipartite transcription factor 0.343473
PRTN3 proteinase 3 0.336876
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.336876
FGGY FGGY carbohydrate kinase domain containing 0.333218
INHA inhibin, alpha 0.332852
CD80 CD80 molecule 0.331025
FCHSD2 FCH and double SH3 domains 2 0.329565
TRIM45 tripartite motif containing 45 0.326646
FAT3 FAT atypical cadherin 3 0.323002
PASK PAS domain containing serine/threonine kinase 0.322637
EMC3 ER membrane protein complex subunit 3 0.322273
IRGM immunity-related GTPase family, M 0.321909
SLC39A2 solute carrier family 39 (zinc transporter), member 2 0.320817
CCL1 chemokine (C-C motif) ligand 1 0.319726
TLR9 toll-like receptor 9 0.319363
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.316819
CCL4 chemokine (C-C motif) ligand 4 0.309928
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 0.308842
NOD2 nucleotide-binding oligomerization domain containing 2 0.301254
IL1RN interleukin 1 receptor antagonist 0.299452
HLA-B major histocompatibility complex, class I, B 0.293334
CHIT1 chitinase 1 (chitotriosidase) 0.291898
NR2E3 nuclear receptor subfamily 2, group E, member 3 0.290462
TUBE1 tubulin, epsilon 1 0.289027
PKP3 plakophilin 3 0.287952
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.282225
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.28151
CHD8 chromodomain helicase DNA binding protein 8 0.274732
PXT1 peroxisomal, testis specific 1 0.264785
DEFA3 defensin, alpha 3, neutrophil-specific 0.254888
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 0.254536
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.251015
B3GAT1 beta-1,3-glucuronyltransferase 1 0.250663
ACPP acid phosphatase, prostate 0.249257
ZNF365 zinc finger protein 365 0.248905
CD5L CD5 molecule-like 0.248554
HAS1 hyaluronan synthase 1 0.247852
CCL21 chemokine (C-C motif) ligand 21 0.24715
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.246799
CTSZ cathepsin Z 0.245396
FN1 fibronectin 1 0.242945
CXCR1 chemokine (C-X-C motif) receptor 1 0.241895
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 0.240497
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.238752
CD40 CD40 molecule, TNF receptor superfamily member 5 0.235616
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.235268
ENO2 enolase 2 (gamma, neuronal) 0.231448
AMIGO2 adhesion molecule with Ig-like domain 2 0.231448
CD19 CD19 molecule 0.227297
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.224884
MMP1 matrix metallopeptidase 1 0.223509
AVP arginine vasopressin 0.22145
MARCO macrophage receptor with collagenous structure 0.21974
PACRG PARK2 co-regulated 0.218374
STAT4 signal transducer and activator of transcription 4 0.218034
CXCL13 chemokine (C-X-C motif) ligand 13 0.217012
PLS1 plastin 1 0.217012
PBX2 pre-B-cell leukemia homeobox 2 0.215653
GCAT glycine C-acetyltransferase 0.211261
ICAM1 intercellular adhesion molecule 1 0.208579
PEPD peptidase D 0.207912
LARS leucyl-tRNA synthetase 0.205254
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 0.203604
CCR1 chemokine (C-C motif) receptor 1 0.203275
CCL11 chemokine (C-C motif) ligand 11 0.202946
CD2 CD2 molecule 0.201962
FEZF1 FEZ family zinc finger 1 0.201962
LMBR1 limb development membrane protein 1 0.201962
MIR197 microRNA 197 0.200006
CD247 CD247 molecule 0.199033
SEPT6 septin 6 0.195183
FEZF2 FEZ family zinc finger 2 0.192657
KMT2A lysine (K)-specific methyltransferase 2A 0.192031
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.191097
PDLIM7 PDZ and LIM domain 7 (enigma) 0.190168
MYBPC1 myosin binding protein C, slow type 0.183835
PDZD4 PDZ domain containing 4 0.183248
TP73 tumor protein p73 0.181798
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.180937
IRF1 interferon regulatory factor 1 0.178403
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.177301
SOD2 superoxide dismutase 2, mitochondrial 0.175146
ZBTB17 zinc finger and BTB domain containing 17 0.173571
TAS1R1 taste receptor, type 1, member 1 0.172291
SAA1 serum amyloid A1 0.172038
TTR transthyretin 0.170789
STK39 serine threonine kinase 39 0.169091
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.168148
IFNL2 interferon, lambda 2 0.166768
IL7R interleukin 7 receptor 0.166319
C4B complement component 4B (Chido blood group) 0.166095
ERV3-1 endogenous retrovirus group 3, member 1 0.163111
GGT1 gamma-glutamyltransferase 1 0.162306
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.161139
CCR7 chemokine (C-C motif) receptor 7 0.158951
CASR calcium-sensing receptor 0.158951