pulmonary fibrosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Similar Terms
Downloads & Tools

Genes

352 genes co-occuring with the disease pulmonary fibrosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TGFB1 transforming growth factor, beta 1 2.09195
SFTPC surfactant protein C 1.83228
CTGF connective tissue growth factor 1.75005
SMAD2 SMAD family member 2 1.66825
HPS1 Hermansky-Pudlak syndrome 1 1.65834
FN1 fibronectin 1 1.61933
SMAD3 SMAD family member 3 1.43464
HPS4 Hermansky-Pudlak syndrome 4 1.41139
HPS3 Hermansky-Pudlak syndrome 3 1.3773
TNF tumor necrosis factor 1.33501
TIMP1 TIMP metallopeptidase inhibitor 1 1.29178
RETNLB resistin like beta 1.26691
SOD2 superoxide dismutase 2, mitochondrial 1.25471
MMP9 matrix metallopeptidase 9 1.22345
SMAD7 SMAD family member 7 1.21998
MMP2 matrix metallopeptidase 2 1.21868
SFTPA2 surfactant protein A2 1.21132
HPS5 Hermansky-Pudlak syndrome 5 1.18496
MUC1 mucin 1, cell surface associated 1.18066
SOD3 superoxide dismutase 3, extracellular 1.13501
MMP12 matrix metallopeptidase 12 1.12024
IL1B interleukin 1, beta 1.11856
TERT telomerase reverse transcriptase 1.11435
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.09335
ACE angiotensin I converting enzyme 1.08202
SFTPD surfactant protein D 1.06522
CCL2 chemokine (C-C motif) ligand 2 1.06312
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 1.04125
AP3B1 adaptor-related protein complex 3, beta 1 subunit 1.03493
ANKRD49 ankyrin repeat domain 49 1.03282
MPO myeloperoxidase 1.01216
CXCL12 chemokine (C-X-C motif) ligand 12 0.994861
FGF7 fibroblast growth factor 7 0.993596
COL1A2 collagen, type I, alpha 2 0.982636
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.96918
PDGFB platelet-derived growth factor beta polypeptide 0.960797
CAT catalase 0.952021
FAM111B family with sequence similarity 111, member B 0.936629
LIPF lipase, gastric 0.925039
MMP1 matrix metallopeptidase 1 0.921736
CCL3 chemokine (C-C motif) ligand 3 0.892948
EDN1 endothelin 1 0.889668
FXYD1 FXYD domain containing ion transport regulator 1 0.88516
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 0.883521
HPS6 Hermansky-Pudlak syndrome 6 0.882701
HARS histidyl-tRNA synthetase 0.880243
TGFB3 transforming growth factor, beta 3 0.865093
CMA1 chymase 1, mast cell 0.857315
FLNC filamin C, gamma 0.836837
IL6 interleukin 6 0.834378
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.833968
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.820437
JUN jun proto-oncogene 0.818796
PRR5L proline rich 5 like 0.816334
CAV1 caveolin 1, caveolae protein, 22kDa 0.815514
NOX4 NADPH oxidase 4 0.813873
SMAD4 SMAD family member 4 0.813462
BLMH bleomycin hydrolase 0.799103
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.793361
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.792951
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 0.780251
CD4 CD4 molecule 0.779432
GPX1 glutathione peroxidase 1 0.777386
GPX5 glutathione peroxidase 5 0.776977
GPX4 glutathione peroxidase 4 0.773296
TIMP2 TIMP metallopeptidase inhibitor 2 0.772887
PLG plasminogen 0.763086
DCN decorin 0.757786
COL1A1 collagen, type I, alpha 1 0.751678
IL1A interleukin 1, alpha 0.751271
CXCR3 chemokine (C-X-C motif) receptor 3 0.749644
CCL13 chemokine (C-C motif) ligand 13 0.74883
FGF2 fibroblast growth factor 2 (basic) 0.748017
CCR2 chemokine (C-C motif) receptor 2 0.738676
TGFBR1 transforming growth factor, beta receptor 1 0.728952
MMP7 matrix metallopeptidase 7 0.725716
FASLG Fas ligand (TNF superfamily, member 6) 0.722077
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.720865
CRISPLD1 cysteine-rich secretory protein LCCL domain containing 1 0.71078
AGFG2 ArfGAP with FG repeats 2 0.709169
CXCL10 chemokine (C-X-C motif) ligand 10 0.705949
RLN1 relaxin 1 0.70434
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.700321
PLAU plasminogen activator, urokinase 0.6939
IL13 interleukin 13 0.689492
TOP1 topoisomerase (DNA) I 0.688291
OSM oncostatin M 0.680697
HMOX1 heme oxygenase 1 0.663181
ACE2 angiotensin I converting enzyme 2 0.653671
TGFB2 transforming growth factor, beta 2 0.649323
ELANE elastase, neutrophil expressed 0.646559
ICAM1 intercellular adhesion molecule 1 0.626103
IGF1 insulin-like growth factor 1 (somatomedin C) 0.624927
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.623359
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.619442
N4BP2 NEDD4 binding protein 2 0.617877
ALB albumin 0.612011
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.609276
STAT1 signal transducer and activator of transcription 1, 91kDa 0.608885
ZNF83 zinc finger protein 83 0.598351
LOX lysyl oxidase 0.596792
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 0.585887
CCL22 chemokine (C-C motif) ligand 22 0.58433
EGR1 early growth response 1 0.581606
SEBOX SEBOX homeobox 0.580828
TPPP2 tubulin polymerization-promoting protein family member 2 0.573439
B3GAT3 beta-1,3-glucuronyltransferase 3 0.572662
RGS14 regulator of G-protein signaling 14 0.568775
CXCR4 chemokine (C-X-C motif) receptor 4 0.568386
FGF1 fibroblast growth factor 1 (acidic) 0.56722
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.566054
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.564889
EGFR epidermal growth factor receptor 0.550134
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.548971
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) 0.543542
TSPO translocator protein (18kDa) 0.542379
CCL17 chemokine (C-C motif) ligand 17 0.539667
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 0.535409
CD44 CD44 molecule (Indian blood group) 0.529222
PLA2G4D phospholipase A2, group IVD (cytosolic) 0.524974
IL4 interleukin 4 0.513033
TNC tenascin C 0.512648
MMP13 matrix metallopeptidase 13 0.511112
LCLAT1 lysocardiolipin acyltransferase 1 0.509959
MMP8 matrix metallopeptidase 8 0.509576
THY1 Thy-1 cell surface antigen 0.503441
AARS alanyl-tRNA synthetase 0.502292
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.499997
SMAD6 SMAD family member 6 0.498849
CYSLTR2 cysteinyl leukotriene receptor 2 0.495793
CCR7 chemokine (C-C motif) receptor 7 0.494648
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.494266
F2R coagulation factor II (thrombin) receptor 0.49274
AQP5 aquaporin 5 0.487027
HUNK hormonally up-regulated Neu-associated kinase 0.480186
SPPL2C signal peptide peptidase like 2C 0.477909
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.472604
WISP1 WNT1 inducible signaling pathway protein 1 0.467306
COL3A1 collagen, type III, alpha 1 0.462016
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.458619
SPP1 secreted phosphoprotein 1 0.457487
FBLL1 fibrillarin-like 1 0.456355
BGN biglycan 0.455978
CXCL8 chemokine (C-X-C motif) ligand 8 0.455224
FOS FBJ murine osteosarcoma viral oncogene homolog 0.455224
AGER advanced glycosylation end product-specific receptor 0.454847
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.451454
FST follistatin 0.450324
TPSAB1 tryptase alpha/beta 1 0.448817
PPARG peroxisome proliferator-activated receptor gamma 0.448064
GSR glutathione reductase 0.445429
EDNRA endothelin receptor type A 0.443547
KRT75 keratin 75, type II 0.439034
PRDX1 peroxiredoxin 1 0.436778
CXCL11 chemokine (C-X-C motif) ligand 11 0.435651
C5AR1 complement component 5a receptor 1 0.434524
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.432646
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 0.43227
DKC1 dyskeratosis congenita 1, dyskerin 0.431519
DDR1 discoidin domain receptor tyrosine kinase 1 0.430393
PCNA proliferating cell nuclear antigen 0.427015
GRP gastrin-releasing peptide 0.42364
ZNF77 zinc finger protein 77 0.422515
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.421765
AGTR1 angiotensin II receptor, type 1 0.42139
FMOD fibromodulin 0.417644
COBL cordon-bleu WH2 repeat protein 0.415398
CLK3 CDC-like kinase 3 0.415024
SRXN1 sulfiredoxin 1 0.413901
CYCS cytochrome c, somatic 0.412405
PLXNA4 plexin A4 0.410161
NFE2L2 nuclear factor, erythroid 2-like 2 0.401572
CD68 CD68 molecule 0.395235
HSPG2 heparan sulfate proteoglycan 2 0.395235
WIBG within bgcn homolog (Drosophila) 0.391141
CRP C-reactive protein, pentraxin-related 0.388538
CYTH2 cytohesin 2 0.384822
F3 coagulation factor III (thromboplastin, tissue factor) 0.384451
HMGB1 high mobility group box 1 0.383337
PLXNC1 plexin C1 0.38111
MREG melanoregulin 0.380739
CD79A CD79a molecule, immunoglobulin-associated alpha 0.379997
IRF5 interferon regulatory factor 5 0.379997
ARID3A AT rich interactive domain 3A (BRIGHT-like) 0.379626
RETN resistin 0.376661
TJP1 tight junction protein 1 0.372958
S100A4 S100 calcium binding protein A4 0.372587
LPAR4 lysophosphatidic acid receptor 4 0.368888
VEGFA vascular endothelial growth factor A 0.368518
BMP7 bone morphogenetic protein 7 0.36741
SFTPB surfactant protein B 0.365932
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.365193
MMP3 matrix metallopeptidase 3 0.364454
WNT7B wingless-type MMTV integration site family, member 7B 0.363716
TRIM16 tripartite motif containing 16 0.362239
MKL1 megakaryoblastic leukemia (translocation) 1 0.359289
MAPK8 mitogen-activated protein kinase 8 0.35892
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.357077
LPO lactoperoxidase 0.351187
XBP1 X-box binding protein 1 0.35082
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.35082
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.348614
LPAR2 lysophosphatidic acid receptor 2 0.347879
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.345308
CXCL5 chemokine (C-X-C motif) ligand 5 0.344207
FOXF1 forkhead box F1 0.342006
MPHOSPH9 M-phase phosphoprotein 9 0.338341
ZBTB25 zinc finger and BTB domain containing 25 0.337608
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 0.334315
CTSE cathepsin E 0.333949
ACTA2 actin, alpha 2, smooth muscle, aorta 0.32774
NKX2-1 NK2 homeobox 1 0.322637
ELN elastin 0.318999
METAP2 methionyl aminopeptidase 2 0.315729
DNTT DNA nucleotidylexotransferase 0.315729
TLR4 toll-like receptor 4 0.313189
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.312827
SULF1 sulfatase 1 0.309928
CTSS cathepsin S 0.309204
APITD1 apoptosis-inducing, TAF9-like domain 1 0.308842
VCAM1 vascular cell adhesion molecule 1 0.307757
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.306672
VWF von Willebrand factor 0.301615
BRD1 bromodomain containing 1 0.301615
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 0.296931
ITGB6 integrin, beta 6 0.292257
GRHL2 grainyhead-like 2 (Drosophila) 0.289386
WNT7A wingless-type MMTV integration site family, member 7A 0.285802
BAX BCL2-associated X protein 0.285444
PTPRA protein tyrosine phosphatase, receptor type, A 0.284371
SFTPA1 surfactant protein A1 0.284371
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.283655
TJP3 tight junction protein 3 0.282225
IL17A interleukin 17A 0.279011
VCAN versican 0.276158
IL9 interleukin 9 0.275445
CCR1 chemokine (C-C motif) receptor 1 0.272953
SPAG11A sperm associated antigen 11A 0.272597
CCL11 chemokine (C-C motif) ligand 11 0.269753
COL18A1 collagen, type XVIII, alpha 1 0.267622
PRTN3 proteinase 3 0.264785
NLRP3 NLR family, pyrin domain containing 3 0.264785
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.264431
TGM2 transglutaminase 2 0.263722
CEP55 centrosomal protein 55kDa 0.262306
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.260891
GCLC glutamate-cysteine ligase, catalytic subunit 0.260184
CXCL9 chemokine (C-X-C motif) ligand 9 0.258064
TP53 tumor protein p53 0.257005
NLRP1 NLR family, pyrin domain containing 1 0.256299
ZEB2 zinc finger E-box binding homeobox 2 0.254183
PARP1 poly (ADP-ribose) polymerase 1 0.251366
BLM Bloom syndrome, RecQ helicase-like 0.250311
HGFAC HGF activator 0.24996
RLN3 relaxin 3 0.248203
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 0.247501
AEBP1 AE binding protein 1 0.245747
TADA3 transcriptional adaptor 3 0.244696
CCL19 chemokine (C-C motif) ligand 19 0.241546
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.241196
ACOT13 acyl-CoA thioesterase 13 0.241196
SPAG11B sperm associated antigen 11B 0.240148
HBA2 hemoglobin, alpha 2 0.238054
SPHK1 sphingosine kinase 1 0.235964
CTSD cathepsin D 0.23353
TLR2 toll-like receptor 2 0.231102
LYZ lysozyme 0.231102
CCL5 chemokine (C-C motif) ligand 5 0.230063
HAND1 heart and neural crest derivatives expressed 1 0.227297
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.226952
FBN1 fibrillin 1 0.226607
NOX1 NADPH oxidase 1 0.225573
ACTA1 actin, alpha 1, skeletal muscle 0.225229
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.222136
PDZK1IP1 PDZK1 interacting protein 1 0.220766
CTH cystathionine gamma-lyase 0.217693
CHIT1 chitinase 1 (chitotriosidase) 0.217693
NLRP6 NLR family, pyrin domain containing 6 0.213959
ACO2 aconitase 2, mitochondrial 0.212945
ANGPT1 angiopoietin 1 0.212608
LGALS3 lectin, galactoside-binding, soluble, 3 0.208245
IGLL1 immunoglobulin lambda-like polypeptide 1 0.204263
PDGFA platelet-derived growth factor alpha polypeptide 0.203933
CTSK cathepsin K 0.203604
CLDN5 claudin 5 0.203275
IL31 interleukin 31 0.202946
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.202618
LGALS1 lectin, galactoside-binding, soluble, 1 0.199356
CCR3 chemokine (C-C motif) receptor 3 0.199356
TXN thioredoxin 0.199033
TM4SF1 transmembrane 4 L six family member 1 0.199033
FOXP3 forkhead box P3 0.198709
CABIN1 calcineurin binding protein 1 0.198709
MAP2K5 mitogen-activated protein kinase kinase 5 0.19742
ATF3 activating transcription factor 3 0.196139
KCNK18 potassium channel, two pore domain subfamily K, member 18 0.19582
TMPRSS11D transmembrane protease, serine 11D 0.195183
WNT3A wingless-type MMTV integration site family, member 3A 0.194548
KEAP1 kelch-like ECH-associated protein 1 0.192657
CST1 cystatin SN 0.192031
CXCR2 chemokine (C-X-C motif) receptor 2 0.190786
CD34 CD34 molecule 0.189551
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.189244
TLE4 transducin-like enhancer of split 4 0.188938
BMP4 bone morphogenetic protein 4 0.188632
LTC4S leukotriene C4 synthase 0.187415
CARD17 caspase recruitment domain family, member 17 0.18621
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.185313
BRD2 bromodomain containing 2 0.185313
LTB4R leukotriene B4 receptor 0.185016
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.185016
CKLF chemokine-like factor 0.184424
CCR4 chemokine (C-C motif) receptor 4 0.183541
WAC WW domain containing adaptor with coiled-coil 0.182957
HLA-C major histocompatibility complex, class I, C 0.182666
ACPP acid phosphatase, prostate 0.17952
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.17896
STX2 syntaxin 2 0.177576
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.176757
AREG amphiregulin 0.175947
NOP10 NOP10 ribonucleoprotein 0.174354
MYL9 myosin, light chain 9, regulatory 0.174093
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.172799
SMAD9 SMAD family member 9 0.172544
KRT19 keratin 19, type I 0.171286
MLPH melanophilin 0.171286
KLF9 Kruppel-like factor 9 0.170299
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.170299
ZEB1 zinc finger E-box binding homeobox 1 0.169091
INSL3 insulin-like 3 (Leydig cell) 0.168617
IL1RN interleukin 1 receptor antagonist 0.168617
GUSB glucuronidase, beta 0.167682
CREB1 cAMP responsive element binding protein 1 0.167452
TFG TRK-fused gene 0.165435
THBS1 thrombospondin 1 0.163938
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.163938
ALOX5 arachidonate 5-lipoxygenase 0.163523
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.161331
ACTB actin, beta 0.161331
NHP2 NHP2 ribonucleoprotein 0.160574
CLDN10 claudin 10 0.160021
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.158778
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.158605
PGF placental growth factor 0.158434
HYAL2 hyaluronoglucosaminidase 2 0.158266
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.144942
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.14467
VIP vasoactive intestinal peptide 0.143025
MRAP melanocortin 2 receptor accessory protein 0.142938
CHGA chromogranin A 0.141668
TAC1 tachykinin, precursor 1 0.139692
ENO2 enolase 2 (gamma, neuronal) 0.136729