pulmonary emphysema Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

135 genes co-occuring with the disease pulmonary emphysema in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 2.10138
ELANE elastase, neutrophil expressed 2.08359
MMP12 matrix metallopeptidase 12 1.63769
KL klotho 1.52028
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1.24037
CELA2B chymotrypsin-like elastase family, member 2B 1.1588
LTBP4 latent transforming growth factor beta binding protein 4 1.1367
CTSG cathepsin G 1.10931
SFTPD surfactant protein D 1.10216
ELN elastin 1.01723
MAN1C1 mannosidase, alpha, class 1C, member 1 0.988535
MMP9 matrix metallopeptidase 9 0.974642
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.97128
CTSS cathepsin S 0.911433
SNRPF small nuclear ribonucleoprotein polypeptide F 0.902799
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.890078
FBN1 fibrillin 1 0.883521
SESN2 sestrin 2 0.879833
AMOTL1 angiomotin like 1 0.873281
FBLN5 fibulin 5 0.86018
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.849536
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 0.807718
MMP1 matrix metallopeptidase 1 0.801564
MYO1D myosin ID 0.778613
FGF23 fibroblast growth factor 23 0.775341
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.77207
RGN regucalcin 0.738271
CTSL cathepsin L 0.737865
BICD1 bicaudal D homolog 1 (Drosophila) 0.714005
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 0.712796
NOX3 NADPH oxidase 3 0.71078
PGF placental growth factor 0.690293
MPO myeloperoxidase 0.689893
ADRA1D adrenoceptor alpha 1D 0.688692
HMOX1 heme oxygenase 1 0.681495
ITGB6 integrin, beta 6 0.658026
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 0.637889
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.615138
ALB albumin 0.61162
TRPV5 transient receptor potential cation channel, subfamily V, member 5 0.608494
FN1 fibronectin 1 0.605372
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.589779
TIMP1 TIMP metallopeptidase inhibitor 1 0.578883
SFTPC surfactant protein C 0.578883
LAX1 lymphocyte transmembrane adaptor 1 0.577327
MMP2 matrix metallopeptidase 2 0.561392
ZNF79 zinc finger protein 79 0.515725
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.508808
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.497703
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.493885
FGF7 fibroblast growth factor 7 0.476772
CSHL1 chorionic somatomammotropin hormone-like 1 0.474877
PLAGL2 pleiomorphic adenoma gene-like 2 0.47374
CCL2 chemokine (C-C motif) ligand 2 0.453716
CCL20 chemokine (C-C motif) ligand 20 0.449571
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.445805
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.445052
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.436778
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.42739
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 0.427015
LBR lamin B receptor 0.41727
WWTR1 WW domain containing transcription regulator 1 0.411657
TLR4 toll-like receptor 4 0.401572
SLPI secretory leukocyte peptidase inhibitor 0.397471
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.393001
GUSB glucuronidase, beta 0.388166
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.387794
IREB2 iron-responsive element binding protein 2 0.387051
MAN2B1 mannosidase, alpha, class 2B, member 1 0.387051
FLT1 fms-related tyrosine kinase 1 0.385565
CDT1 chromatin licensing and DNA replication factor 1 0.384822
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.374068
DYNLL1 dynein, light chain, LC8-type 1 0.366671
MSRA methionine sulfoxide reductase A 0.360395
TIMP2 TIMP metallopeptidase inhibitor 2 0.35892
ALYREF Aly/REF export factor 0.357077
CELA1 chymotrypsin-like elastase family, member 1 0.356341
CXCL5 chemokine (C-X-C motif) ligand 5 0.355604
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.348246
BLVRA biliverdin reductase A 0.347511
LY96 lymphocyte antigen 96 0.340906
CTSE cathepsin E 0.336876
CXCL2 chemokine (C-X-C motif) ligand 2 0.333218
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 0.332487
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.33066
TNF tumor necrosis factor 0.330295
TGFB1 transforming growth factor, beta 1 0.328469
CCR6 chemokine (C-C motif) receptor 6 0.313552
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.313189
MMP8 matrix metallopeptidase 8 0.307757
FGF2 fibroblast growth factor 2 (basic) 0.307395
HHIP hedgehog interacting protein 0.306672
VEGFA vascular endothelial growth factor A 0.300533
WDFY2 WD repeat and FYVE domain containing 2 0.295851
PLCH2 phospholipase C, eta 2 0.289744
LTA4H leukotriene A4 hydrolase 0.287235
MMP7 matrix metallopeptidase 7 0.284013
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.272241
SIRT1 sirtuin 1 0.27153
CRABP1 cellular retinoic acid binding protein 1 0.269753
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.269043
SMAD2 SMAD family member 2 0.263014
GPX2 glutathione peroxidase 2 0.257005
DNTT DNA nucleotidylexotransferase 0.248203
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.246799
PRDM2 PR domain containing 2, with ZNF domain 0.240497
NOS3 nitric oxide synthase 3 (endothelial cell) 0.23492
CRABP2 cellular retinoic acid binding protein 2 0.232836
BCO1 beta-carotene oxygenase 1 0.229716
AZU1 azurocidin 1 0.227297
CCL3 chemokine (C-C motif) ligand 3 0.216332
DCN decorin 0.210589
CADM1 cell adhesion molecule 1 0.207578
CDC6 cell division cycle 6 0.199356
ABHD2 abhydrolase domain containing 2 0.197742
ECI1 enoyl-CoA delta isomerase 1 0.194865
CXCL8 chemokine (C-X-C motif) ligand 8 0.194548
CST4 cystatin S 0.192971
DNM1L dynamin 1-like 0.189859
CAT catalase 0.178126
HBA2 hemoglobin, alpha 2 0.177851
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.177851
GSTM3 glutathione S-transferase mu 3 (brain) 0.169571
BAX BCL2-associated X protein 0.166095
PCNA proliferating cell nuclear antigen 0.158097
HES5 hes family bHLH transcription factor 5 0.145231
IL2RA interleukin 2 receptor, alpha 0.145157
MUC1 mucin 1, cell surface associated 0.14515
PROX1 prospero homeobox 1 0.145117
NELFCD negative elongation factor complex member C/D 0.144384
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.143062
IL10 interleukin 10 0.141433
CP ceruloplasmin (ferroxidase) 0.139794
HBA1 hemoglobin, alpha 1 0.134326
HRAS Harvey rat sarcoma viral oncogene homolog 0.126497