pulmonary embolism Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An artery disease characterized by a blockage of the main artery of the lung or one of its branches by a substance that has travelled from elsewhere in the body, e.g. a blood clot. (Human Disease Ontology, DOID_9477)
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Genes

157 genes co-occuring with the disease pulmonary embolism in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PLAT plasminogen activator, tissue 2.37215
F5 coagulation factor V (proaccelerin, labile factor) 2.2993
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 2.21164
F2 coagulation factor II (thrombin) 2.09102
F3 coagulation factor III (thromboplastin, tissue factor) 1.92576
PROS1 protein S (alpha) 1.79345
PLG plasminogen 1.76683
TNNI3 troponin I type 3 (cardiac) 1.65295
TNNT2 troponin T type 2 (cardiac) 1.58671
F10 coagulation factor X 1.5476
FAM155B family with sequence similarity 155, member B 1.54142
F8 coagulation factor VIII, procoagulant component 1.35158
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.31668
ALB albumin 1.31493
PF4 platelet factor 4 1.24689
FABP3 fatty acid binding protein 3, muscle and heart 1.21392
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 1.13797
VKORC1 vitamin K epoxide reductase complex, subunit 1 1.13459
TBX1 T-box 1 1.11099
ERF Ets2 repressor factor 1.06186
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.0463
F7 coagulation factor VII (serum prothrombin conversion accelerator) 1.0383
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 1.03367
CRP C-reactive protein, pentraxin-related 0.99697
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.965405
WASH7P WAS protein family homolog 7 pseudogene 0.902799
WASH1 WAS protein family homolog 1 0.898693
WASH6P WAS protein family homolog 6 pseudogene 0.89582
NPPB natriuretic peptide B 0.890078
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.867959
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.847898
SZRD1 SUZ RNA binding domain containing 1 0.819616
APOH apolipoprotein H (beta-2-glycoprotein I) 0.817155
TXNL4B thioredoxin-like 4B 0.791721
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 0.785574
THBD thrombomodulin 0.784755
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.779841
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3 0.775341
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.774114
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.773705
MB myoglobin 0.733406
NONO non-POU domain containing, octamer-binding 0.727333
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.708767
GDF15 growth differentiation factor 15 0.691094
PDZK1IP1 PDZK1 interacting protein 1 0.672722
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 0.656837
VWF von Willebrand factor 0.654463
CDK11A cyclin-dependent kinase 11A 0.652484
ASRGL1 asparaginase like 1 0.644586
F12 coagulation factor XII (Hageman factor) 0.640251
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 0.625711
BET1 Bet1 golgi vesicular membrane trafficking protein 0.597961
TBXAS1 thromboxane A synthase 1 (platelet) 0.594454
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.568386
CPB2 carboxypeptidase B2 (plasma) 0.567997
LARS leucyl-tRNA synthetase 0.562558
PRRC2A proline-rich coiled-coil 2A 0.554015
F9 coagulation factor IX 0.547032
PLAU plasminogen activator, urokinase 0.546644
GSTZ1 glutathione S-transferase zeta 1 0.545481
PER1 period circadian clock 1 0.54393
IGLV2-14 immunoglobulin lambda variable 2-14 0.542379
ACE angiotensin I converting enzyme 0.533861
BRI3 brain protein I3 0.514956
IFNL2 interferon, lambda 2 0.511496
PGRMC1 progesterone receptor membrane component 1 0.497703
COX5A cytochrome c oxidase subunit Va 0.49274
SNF8 SNF8, ESCRT-II complex subunit 0.46466
NPPA natriuretic peptide A 0.450701
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.4443
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 0.433772
ADGRE5 adhesion G protein-coupled receptor E5 0.431144
RAET1E retinoic acid early transcript 1E 0.428516
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.416521
IARS isoleucyl-tRNA synthetase 0.406051
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.403438
WIPF2 WAS/WASL interacting protein family, member 2 0.398589
ESR1 estrogen receptor 1 0.391141
C6ORF25 chromosome 6 open reading frame 25 0.388538
UBN1 ubinuclein 1 0.379626
CINP cyclin-dependent kinase 2 interacting protein 0.37629
PPIC peptidylprolyl isomerase C (cyclophilin C) 0.373328
THEM5 thioesterase superfamily member 5 0.372958
FDPS farnesyl diphosphate synthase 0.371847
FBL fibrillarin 0.371847
DCLRE1C DNA cross-link repair 1C 0.368149
IL31RA interleukin 31 receptor A 0.34384
ELP2 elongator acetyltransferase complex subunit 2 0.338707
RGS7 regulator of G-protein signaling 7 0.335778
CYS1 cystin 1 0.331391
PF4V1 platelet factor 4 variant 1 0.32774
MAEA macrophage erythroblast attacher 0.324094
CPSF3L cleavage and polyadenylation specific factor 3-like 0.323002
FBLL1 fibrillarin-like 1 0.318272
KLK3 kallikrein-related peptidase 3 0.315003
GP6 glycoprotein VI (platelet) 0.305587
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.300894
MGP matrix Gla protein 0.290103
CLEC3B C-type lectin domain family 3, member B 0.289386
OLFML3 olfactomedin-like 3 0.28831
EVL Enah/Vasp-like 0.28616
IL31 interleukin 31 0.281153
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 0.278654
F13A1 coagulation factor XIII, A1 polypeptide 0.271886
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.270108
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.267267
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 0.263014
MMP9 matrix metallopeptidase 9 0.262306
WAC WW domain containing adaptor with coiled-coil 0.258417
AES amino-terminal enhancer of split 0.255594
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.255594
SELE selectin E 0.253127
NPR1 natriuretic peptide receptor 1 0.24715
GUCY2C guanylate cyclase 2C 0.246448
CCL2 chemokine (C-C motif) ligand 2 0.245747
DCT dopachrome tautomerase 0.243645
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.243295
C11ORF40 chromosome 11 open reading frame 40 0.241196
CTNS cystinosin, lysosomal cystine transporter 0.240847
HSPG2 heparan sulfate proteoglycan 2 0.233878
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.233878
GYLTL1B glycosyltransferase-like 1B 0.232836
ANO7P1 anoctamin 7 pseudogene 1 0.230409
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.230063
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.228679
EDN1 endothelin 1 0.226262
MPO myeloperoxidase 0.223853
ZNF135 zinc finger protein 135 0.223509
ITGAD integrin, alpha D 0.214636
APOLD1 apolipoprotein L domain containing 1 0.214297
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.212945
USO1 USO1 vesicle transport factor 0.211261
PDE9A phosphodiesterase 9A 0.203275
ATAD3C ATPase family, AAA domain containing 3C 0.201308
XCL1 chemokine (C motif) ligand 1 0.196139
CDAN1 codanin 1 0.194548
CALU calumenin 0.193915
ARR3 arrestin 3, retinal (X-arrestin) 0.188632
FAM131C family with sequence similarity 131, member C 0.183541
STK10 serine/threonine kinase 10 0.183248
CTPS1 CTP synthase 1 0.180652
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 0.17896
TTK TTK protein kinase 0.177301
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.174617
PPT1 palmitoyl-protein thioesterase 1 0.174354
TTR transthyretin 0.174354
GAS6 growth arrest-specific 6 0.173571
PEX14 peroxisomal biogenesis factor 14 0.170054
HRAS Harvey rat sarcoma viral oncogene homolog 0.167682
ICK intestinal cell (MAK-like) kinase 0.166995
GIF gastric intrinsic factor (vitamin B synthesis) 0.166544
IGLV9-49 immunoglobulin lambda variable 9-49 0.164359
EGFR epidermal growth factor receptor 0.163729
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.161912
HP haptoglobin 0.160203
MMP2 matrix metallopeptidase 2 0.159658
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.158434