pulmonary edema Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

252 genes co-occuring with the disease pulmonary edema in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ALB albumin 1.953
AQP5 aquaporin 5 1.41753
MPO myeloperoxidase 1.40089
TNF tumor necrosis factor 1.36989
AQP1 aquaporin 1 (Colton blood group) 1.23516
SOD2 superoxide dismutase 2, mitochondrial 1.21132
NPPA natriuretic peptide A 1.20829
ACE angiotensin I converting enzyme 1.2031
DNAH8 dynein, axonemal, heavy chain 8 1.14433
IL1B interleukin 1, beta 1.13966
CSAD cysteine sulfinic acid decarboxylase 1.13416
CAT catalase 1.07782
IL2 interleukin 2 1.04462
ELANE elastase, neutrophil expressed 1.02018
CLDN18 claudin 18 1.00414
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.99908
IL6 interleukin 6 0.978006
MYLK3 myosin light chain kinase 3 0.964148
CDH5 cadherin 5, type 2 (vascular endothelium) 0.916375
NOS3 nitric oxide synthase 3 (endothelial cell) 0.869596
AVP arginine vasopressin 0.865912
FMO5 flavin containing monooxygenase 5 0.852402
ICAM1 intercellular adhesion molecule 1 0.845031
TAC1 tachykinin, precursor 1 0.816334
MYLK myosin light chain kinase 0.812232
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.80977
FGF7 fibroblast growth factor 7 0.807308
AGER advanced glycosylation end product-specific receptor 0.801974
C5AR1 complement component 5a receptor 1 0.783936
ARHGAP35 Rho GTPase activating protein 35 0.783526
FMO1 flavin containing monooxygenase 1 0.771661
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.756156
CLDN5 claudin 5 0.753713
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.75005
REN renin 0.747204
AMY2A amylase, alpha 2A (pancreatic) 0.733406
KNG1 kininogen 1 0.732596
CXCL8 chemokine (C-X-C motif) ligand 8 0.731786
FMO4 flavin containing monooxygenase 4 0.721673
FMO2 flavin containing monooxygenase 2 (non-functional) 0.70233
CLDN4 claudin 4 0.700321
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.696306
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.691094
CORO1A coronin, actin binding protein, 1A 0.679499
OCLN occludin 0.671527
PLAT plasminogen activator, tissue 0.670333
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.667152
F2 coagulation factor II (thrombin) 0.663181
TF transferrin 0.658026
TNNT2 troponin T type 2 (cardiac) 0.652089
KIAA0101 KIAA0101 0.631205
HMOX1 heme oxygenase 1 0.621008
TNNI3 troponin I type 3 (cardiac) 0.612792
INS insulin 0.60186
MMP9 matrix metallopeptidase 9 0.6003
VEGFA vascular endothelial growth factor A 0.6003
EDNRA endothelin receptor type A 0.596792
EDN1 endothelin 1 0.595623
MLX MLX, MAX dimerization protein 0.595623
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.594064
PIH2 pregnancy-induced hypertension syndrome-related protein 0.589779
WBP2 WW domain binding protein 2 0.589001
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 0.587054
TJP1 tight junction protein 1 0.585497
IL1A interleukin 1, alpha 0.580828
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.580439
GPX5 glutathione peroxidase 5 0.575772
F3 coagulation factor III (thromboplastin, tissue factor) 0.57305
GPX4 glutathione peroxidase 4 0.572662
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.565666
TLR4 toll-like receptor 4 0.565666
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.561781
NFYC nuclear transcription factor Y, gamma 0.557509
GPX1 glutathione peroxidase 1 0.556732
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.55518
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 0.552463
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 0.551298
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.548971
LPGAT1 lysophosphatidylglycerol acyltransferase 1 0.53657
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.529608
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 0.52729
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.525746
BCHE butyrylcholinesterase 0.52536
NPR1 natriuretic peptide receptor 1 0.523045
GUCY2C guanylate cyclase 2C 0.522273
CCL3 chemokine (C-C motif) ligand 3 0.51919
CD59 CD59 molecule, complement regulatory protein 0.518805
COX5A cytochrome c oxidase subunit Va 0.51842
TBXAS1 thromboxane A synthase 1 (platelet) 0.517265
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.50689
HLA-C major histocompatibility complex, class I, C 0.50459
ANGPT1 angiopoietin 1 0.49274
KRT84 keratin 84, type II 0.490072
SFTPB surfactant protein B 0.485505
TACR1 tachykinin receptor 1 0.483604
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.483604
SAMD4B sterile alpha motif domain containing 4B 0.480186
CRP C-reactive protein, pentraxin-related 0.471468
NOS2 nitric oxide synthase 2, inducible 0.468819
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.467684
WRAP73 WD repeat containing, antisense to TP73 0.463149
ADORA2B adenosine A2b receptor 0.455224
HAT1 histone acetyltransferase 1 0.454093
PLA2G1B phospholipase A2, group IB (pancreas) 0.443171
ARHGAP24 Rho GTPase activating protein 24 0.442418
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.44129
TMEM53 transmembrane protein 53 0.438658
ANGPT2 angiopoietin 2 0.426265
ATP11A ATPase, class VI, type 11A 0.42214
ABR active BCR-related 0.421765
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.418394
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 0.411283
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.410535
HMGB1 high mobility group box 1 0.409414
SMOX spermine oxidase 0.405305
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.398962
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.398589
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.387794
CLDN3 claudin 3 0.386308
LDHAL6B lactate dehydrogenase A-like 6B 0.385936
LIMA1 LIM domain and actin binding 1 0.383337
ADRB2 adrenoceptor beta 2, surface 0.379256
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 0.376661
S1PR1 sphingosine-1-phosphate receptor 1 0.371477
MB myoglobin 0.371107
H1FX H1 histone family, member X 0.368518
VWF von Willebrand factor 0.364454
THBD thrombomodulin 0.362609
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.35892
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.353395
GPX2 glutathione peroxidase 2 0.353027
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.352659
SGK1 serum/glucocorticoid regulated kinase 1 0.351923
FMO3 flavin containing monooxygenase 3 0.345308
NOVA1 neuro-oncological ventral antigen 1 0.337608
FAT2 FAT atypical cadherin 2 0.336876
MED19 mediator complex subunit 19 0.331391
LDHAL6A lactate dehydrogenase A-like 6A 0.329565
TPX2 TPX2, microtubule-associated 0.32774
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.327375
PAOX polyamine oxidase (exo-N4-amino) 0.326281
TRIM37 tripartite motif containing 37 0.325552
MAP2K7 mitogen-activated protein kinase kinase 7 0.325552
ANGPT4 angiopoietin 4 0.325187
NPY neuropeptide Y 0.321181
PGF placental growth factor 0.321181
GSR glutathione reductase 0.320817
SFTPC surfactant protein C 0.317909
BAG2 BCL2-associated athanogene 2 0.315003
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.311377
HSPA1A heat shock 70kDa protein 1A 0.310652
CYB5A cytochrome b5 type A (microsomal) 0.310652
GGT1 gamma-glutamyltransferase 1 0.305948
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.302337
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.300533
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.298731
FN1 fibronectin 1 0.298011
FBXO8 F-box protein 8 0.296211
MME membrane metallo-endopeptidase 0.293334
SFTPD surfactant protein D 0.292616
WTIP Wilms tumor 1 interacting protein 0.289027
CTNND1 catenin (cadherin-associated protein), delta 1 0.285444
TSPO translocator protein (18kDa) 0.284728
NPS neuropeptide S 0.280082
LARS leucyl-tRNA synthetase 0.277584
EMILIN1 elastin microfibril interfacer 1 0.273664
PRAMEF12 PRAME family member 12 0.27153
G6PD glucose-6-phosphate dehydrogenase 0.269043
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.267622
CAPN5 calpain 5 0.264431
NOX4 NADPH oxidase 4 0.263014
TGFBR1 transforming growth factor, beta receptor 1 0.263014
GJA1 gap junction protein, alpha 1, 43kDa 0.261599
LIG3 ligase III, DNA, ATP-dependent 0.260184
CCL2 chemokine (C-C motif) ligand 2 0.259477
SCARB2 scavenger receptor class B, member 2 0.254183
MYL12B myosin, light chain 12B, regulatory 0.251366
ARSI arylsulfatase family, member I 0.24996
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.248203
ESAM endothelial cell adhesion molecule 0.247501
VIP vasoactive intestinal peptide 0.24715
FPR2 formyl peptide receptor 2 0.245046
MAPK14 mitogen-activated protein kinase 14 0.243645
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.239799
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.237357
ARR3 arrestin 3, retinal (X-arrestin) 0.23492
HRH1 histamine receptor H1 0.232836
HES5 hes family bHLH transcription factor 5 0.232489
FLT1 fms-related tyrosine kinase 1 0.232142
COPA coatomer protein complex, subunit alpha 0.231795
PROCR protein C receptor, endothelial 0.226262
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.225573
ZFP36 ZFP36 ring finger protein 0.224884
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.22454
RALB v-ral simian leukemia viral oncogene homolog B 0.224196
HSPA4 heat shock 70kDa protein 4 0.224196
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.224196
CD226 CD226 molecule 0.223853
PDE5A phosphodiesterase 5A, cGMP-specific 0.223509
SELE selectin E 0.223165
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.223165
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.222479
CSHL1 chorionic somatomammotropin hormone-like 1 0.222136
MTO1 mitochondrial tRNA translation optimization 1 0.220081
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.21974
VCL vinculin 0.219057
TGFB1 transforming growth factor, beta 1 0.215314
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.214975
LDHC lactate dehydrogenase C 0.212945
LDHA lactate dehydrogenase A 0.210253
LPIN2 lipin 2 0.20658
EGLN1 egl-9 family hypoxia-inducible factor 1 0.20658
RIPK3 receptor-interacting serine-threonine kinase 3 0.205585
AQP2 aquaporin 2 (collecting duct) 0.203275
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.199681
LDHB lactate dehydrogenase B 0.199033
TRAPPC9 trafficking protein particle complex 9 0.198064
PKN1 protein kinase N1 0.196139
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 0.194548
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.1936
ACE2 angiotensin I converting enzyme 2 0.192344
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.190786
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.189551
MAP2K2 mitogen-activated protein kinase kinase 2 0.189244
ASIC2 acid sensing (proton gated) ion channel 2 0.187415
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.186811
CD47 CD47 molecule 0.18591
CTTN cortactin 0.182957
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.180367
WRNIP1 Werner helicase interacting protein 1 0.179802
CLDN6 claudin 6 0.179802
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.179239
KLRG1 killer cell lectin-like receptor subfamily G, member 1 0.177029
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 0.173571
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.171036
CPB1 carboxypeptidase B1 (tissue) 0.169571
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.168381
GCLC glutamate-cysteine ligase, catalytic subunit 0.168148
MMP2 matrix metallopeptidase 2 0.167224
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 0.166544
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 0.165874
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 0.165001
CCDC27 coiled-coil domain containing 27 0.162306
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.162109
GUSB glucuronidase, beta 0.161523
HABP2 hyaluronan binding protein 2 0.160387
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.160203
ALPPL2 alkaline phosphatase, placental-like 2 0.160021
ALPP alkaline phosphatase, placental 0.159658
ALPL alkaline phosphatase, liver/bone/kidney 0.15948
KERA keratocan 0.158097
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.157929