pulmonary artery Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description An artery that conveys venous blood from the heart to the lungs. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000778)
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Genes

718 proteins co-occuring with the tissue pulmonary artery in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
EDN1 endothelin 1 2.38751
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 2.35696
NPPA natriuretic peptide A 2.23097
NOS3 nitric oxide synthase 3 (endothelial cell) 2.17554
EDNRA endothelin receptor type A 2.16708
PDZK1IP1 PDZK1 interacting protein 1 2.06049
PDE5A phosphodiesterase 5A, cGMP-specific 1.87546
GUCY2C guanylate cyclase 2C 1.85843
NPR1 natriuretic peptide receptor 1 1.85534
ALB albumin 1.84042
ACE angiotensin I converting enzyme 1.83323
KNG1 kininogen 1 1.80564
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 1.74675
CPB1 carboxypeptidase B1 (tissue) 1.73031
PATE1 prostate and testis expressed 1 1.70793
REN renin 1.61659
SOD2 superoxide dismutase 2, mitochondrial 1.57454
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 1.5594
PLAT plasminogen activator, tissue 1.55552
TACR2 tachykinin receptor 2 1.45657
NPPB natriuretic peptide B 1.44079
ELN elastin 1.40018
ADM adrenomedullin 1.39376
TBX1 T-box 1 1.33817
CAT catalase 1.31379
TNF tumor necrosis factor 1.29849
PTP4A1 protein tyrosine phosphatase type IVA, member 1 1.28681
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.27068
PTGIS prostaglandin I2 (prostacyclin) synthase 1.26844
TAC1 tachykinin, precursor 1 1.26576
NOX4 NADPH oxidase 4 1.2345
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.2238
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.21713
MLX MLX, MAX dimerization protein 1.2109
PCNA proliferating cell nuclear antigen 1.19978
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.19267
YME1L1 YME1-like 1 ATPase 1.19267
TRPC1 transient receptor potential cation channel, subfamily C, member 1 1.18734
VWF von Willebrand factor 1.17047
PGF placental growth factor 1.16382
EDNRB endothelin receptor type B 1.14742
NOTCH1 notch 1 1.1328
MPO myeloperoxidase 1.12881
TRPC6 transient receptor potential cation channel, subfamily C, member 6 1.12748
UTS2 urotensin 2 1.1266
TBXAS1 thromboxane A synthase 1 (platelet) 1.12527
IL6 interleukin 6 1.11863
SLC38A4 solute carrier family 38, member 4 1.11686
CSN3 casein kappa 1.11066
LBR lamin B receptor 1.09739
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.08811
PLG plasminogen 1.0806
EDN3 endothelin 3 1.07309
F3 coagulation factor III (thromboplastin, tissue factor) 1.06823
CALCA calcitonin-related polypeptide alpha 1.06603
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.06515
VIP vasoactive intestinal peptide 1.06118
F2 coagulation factor II (thrombin) 1.05985
COPA coatomer protein complex, subunit alpha 1.05809
TGFB1 transforming growth factor, beta 1 1.04577
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 1.04181
IL1B interleukin 1, beta 1.04137
CAV1 caveolin 1, caveolae protein, 22kDa 1.00152
CSAD cysteine sulfinic acid decarboxylase 0.995425
MMP2 matrix metallopeptidase 2 0.993249
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.992814
TNNT2 troponin T type 2 (cardiac) 0.991074
TACR1 tachykinin receptor 1 0.989335
F8 coagulation factor VIII, procoagulant component 0.987597
VEGFA vascular endothelial growth factor A 0.985425
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.984556
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.980217
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 0.978917
ACVRL1 activin A receptor type II-like 1 0.971984
TBXA2R thromboxane A2 receptor 0.962471
BCO1 beta-carotene oxygenase 1 0.958154
DNAH8 dynein, axonemal, heavy chain 8 0.956859
SMAD9 SMAD family member 9 0.952547
PDGFB platelet-derived growth factor beta polypeptide 0.950823
BMPR1A bone morphogenetic protein receptor, type IA 0.949531
TACR3 tachykinin receptor 3 0.943935
BLVRA biliverdin reductase A 0.938777
TNNI3 troponin I type 3 (cardiac) 0.928478
CTH cystathionine gamma-lyase 0.92805
ANGPT1 angiopoietin 1 0.923767
CRP C-reactive protein, pentraxin-related 0.919488
KIAA0101 KIAA0101 0.907109
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 0.89647
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.879935
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.879089
AVP arginine vasopressin 0.879089
FN1 fibronectin 1 0.875706
HMOX1 heme oxygenase 1 0.873594
TAGLN transgelin 0.865577
PDLIM1 PDZ and LIM domain 1 0.860942
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.850845
MYLK myosin light chain kinase 0.849585
MAPK14 mitogen-activated protein kinase 14 0.841608
S100A4 S100 calcium binding protein A4 0.833223
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.830709
TNC tenascin C 0.829034
HBA2 hemoglobin, alpha 2 0.824013
FGF2 fibroblast growth factor 2 (basic) 0.814815
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.814397
MME membrane metallo-endopeptidase 0.812726
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 0.807299
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.805213
NOS2 nitric oxide synthase 2, inducible 0.804796
BMP4 bone morphogenetic protein 4 0.803544
CCL2 chemokine (C-C motif) ligand 2 0.802293
ECE1 endothelin converting enzyme 1 0.796041
ERAS ES cell expressed Ras 0.79146
F5 coagulation factor V (proaccelerin, labile factor) 0.780648
MMP9 matrix metallopeptidase 9 0.77774
ADCY2 adenylate cyclase 2 (brain) 0.7711
C5AR1 complement component 5a receptor 1 0.764468
CLCN3 chloride channel, voltage-sensitive 3 0.757432
VASP vasodilator-stimulated phosphoprotein 0.757018
EXOC2 exocyst complex component 2 0.755777
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.751645
SMAD2 SMAD family member 2 0.747927
ICAM1 intercellular adhesion molecule 1 0.738854
F2R coagulation factor II (thrombin) receptor 0.738854
TIMP2 TIMP metallopeptidase inhibitor 2 0.737206
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 0.735971
HLA-DOB major histocompatibility complex, class II, DO beta 0.726097
TARM1 T cell-interacting, activating receptor on myeloid cells 1 0.725685
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.724041
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.723631
NPPC natriuretic peptide C 0.72322
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.722398
DLL1 delta-like 1 (Drosophila) 0.721577
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 0.716651
CTGF connective tissue growth factor 0.713369
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.704764
CDH5 cadherin 5, type 2 (vascular endothelium) 0.701489
TIMP1 TIMP metallopeptidase inhibitor 1 0.700671
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.700671
LOX lysyl oxidase 0.693311
MAPK3 mitogen-activated protein kinase 3 0.691676
SRL sarcalumenin 0.690451
HDX highly divergent homeobox 0.688409
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.685959
PPARG peroxisome proliferator-activated receptor gamma 0.684735
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.681471
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.67984
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.679433
SOD3 superoxide dismutase 3, extracellular 0.676987
PTCH1 patched 1 0.670064
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.66925
IGLV2-14 immunoglobulin lambda variable 2-14 0.665182
DNTT DNA nucleotidylexotransferase 0.661929
BMP2 bone morphogenetic protein 2 0.661523
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.659085
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.649749
HBA1 hemoglobin, alpha 1 0.647316
HIF3A hypoxia inducible factor 3, alpha subunit 0.646505
GPX1 glutathione peroxidase 1 0.644074
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.642454
KCNG3 potassium channel, voltage gated modifier subfamily G, member 3 0.641643
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 0.63719
TXN thioredoxin 0.633953
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.63274
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.631931
JUN jun proto-oncogene 0.630314
PDE4A phosphodiesterase 4A, cAMP-specific 0.627485
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.626677
ANG angiogenin, ribonuclease, RNase A family, 5 0.621024
CCND1 cyclin D1 0.620217
ADRB2 adrenoceptor beta 2, surface 0.61941
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.616586
YOD1 YOD1 deubiquitinase 0.616183
SELE selectin E 0.61175
ZCCHC7 zinc finger, CCHC domain containing 7 0.610138
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.609735
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 0.60893
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.606916
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.606514
PRM3 protamine 3 0.603697
GLB1 galactosidase, beta 1 0.602088
EGLN3 egl-9 family hypoxia-inducible factor 3 0.601686
CLCA2 chloride channel accessory 2 0.599675
CYBA cytochrome b-245, alpha polypeptide 0.595656
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.59405
HAND2 heart and neural crest derivatives expressed 2 0.589635
CXCL8 chemokine (C-X-C motif) ligand 8 0.588431
PGRMC1 progesterone receptor membrane component 1 0.585224
SMOX spermine oxidase 0.578816
GPR182 G protein-coupled receptor 182 0.578016
MPST mercaptopyruvate sulfurtransferase 0.577615
BAX BCL2-associated X protein 0.577615
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.577615
KCNK6 potassium channel, two pore domain subfamily K, member 6 0.577615
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.576415
HMOX2 heme oxygenase 2 0.574816
CYGB cytoglobin 0.569222
PLN phospholamban 0.565631
TPH1 tryptophan hydroxylase 1 0.565232
GPX5 glutathione peroxidase 5 0.564833
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.561644
TRIM39-RPP21 TRIM39-RPP21 readthrough 0.560847
GPX4 glutathione peroxidase 4 0.560847
IGLV2-8 immunoglobulin lambda variable 2-8 0.560449
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.558457
SFTPA1 surfactant protein A1 0.551695
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.549709
ANO1 anoctamin 1, calcium activated chloride channel 0.549312
TGFBR1 transforming growth factor, beta receptor 1 0.546533
MYH11 myosin, heavy chain 11, smooth muscle 0.545739
ETV3 ets variant 3 0.544946
PRB3 proline-rich protein BstNI subfamily 3 0.543359
INS insulin 0.541377
COL1A2 collagen, type I, alpha 2 0.540188
PLA2G1B phospholipase A2, group IB (pancreas) 0.539396
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.538604
ARR3 arrestin 3, retinal (X-arrestin) 0.537416
AMY2A amylase, alpha 2A (pancreatic) 0.533856
EPHX2 epoxide hydrolase 2, cytoplasmic 0.531879
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.527139
CLCA4 chloride channel accessory 4 0.524771
LIMK2 LIM domain kinase 2 0.524771
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.523194
PHF12 PHD finger protein 12 0.523194
RYR3 ryanodine receptor 3 0.520435
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.519253
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.511778
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.510599
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor 0.507849
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.506279
MMP1 matrix metallopeptidase 1 0.505887
THBD thrombomodulin 0.504318
TXNDC17 thioredoxin domain containing 17 0.501574
ACTG1 actin gamma 1 0.501182
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.500398
CDKN2A cyclin-dependent kinase inhibitor 2A 0.497657
PRDX5 peroxiredoxin 5 0.496483
XDH xanthine dehydrogenase 0.496092
RPP21 ribonuclease P/MRP 21kDa subunit 0.495309
MAEA macrophage erythroblast attacher 0.492963
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 0.492963
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 0.483596
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.481259
CTTN cortactin 0.480091
CD34 CD34 molecule 0.477756
PROM1 prominin 1 0.476979
NPY neuropeptide Y 0.476589
PTAFR platelet-activating factor receptor 0.474258
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.471927
CAST calpastatin 0.470763
CALD1 caldesmon 1 0.466885
F9 coagulation factor IX 0.463787
CMA1 chymase 1, mast cell 0.463787
TPR translocated promoter region, nuclear basket protein 0.460692
SMAD3 SMAD family member 3 0.459918
CBLN2 cerebellin 2 precursor 0.458759
RRBP1 ribosome binding protein 1 0.456828
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.456442
PAH phenylalanine hydroxylase 0.456055
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.454512
ADCY6 adenylate cyclase 6 0.454126
KMT2A lysine (K)-specific methyltransferase 2A 0.453355
CENPB centromere protein B, 80kDa 0.449886
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.449501
G6PD glucose-6-phosphate dehydrogenase 0.448731
OPN3 opsin 3 0.446038
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 0.444115
SCO2 SCO2 cytochrome c oxidase assembly protein 0.439507
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.439123
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 0.433757
RPIA ribose 5-phosphate isomerase A 0.433757
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 0.433374
MGP matrix Gla protein 0.432225
APLN apelin 0.431843
EDN2 endothelin 2 0.430312
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.42993
BIRC5 baculoviral IAP repeat containing 5 0.428783
ELANE elastase, neutrophil expressed 0.428018
RETNLB resistin like beta 0.426872
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.424199
VCAM1 vascular cell adhesion molecule 1 0.424199
EGR1 early growth response 1 0.42191
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.421529
AQP1 aquaporin 1 (Colton blood group) 0.421148
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.41848
PRKG1 protein kinase, cGMP-dependent, type I 0.417718
CLCA1 chloride channel accessory 1 0.416576
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.414673
PRAC1 prostate cancer susceptibility candidate 1 0.412391
NOS1 nitric oxide synthase 1 (neuronal) 0.411251
PF4 platelet factor 4 0.410491
MYLK3 myosin light chain kinase 3 0.407453
SMAD6 SMAD family member 6 0.406315
AGER advanced glycosylation end product-specific receptor 0.405935
FUT2 fucosyltransferase 2 (secretor status included) 0.405555
GAPVD1 GTPase activating protein and VPS9 domains 1 0.405555
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.402901
IGF1 insulin-like growth factor 1 (somatomedin C) 0.401765
GPR37L1 G protein-coupled receptor 37 like 1 0.398357
CRELD1 cysteine-rich with EGF-like domains 1 0.396087
GPR135 G protein-coupled receptor 135 0.395331
HMGB1 high mobility group box 1 0.395331
IGLV6-57 immunoglobulin lambda variable 6-57 0.394953
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.392686
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.391931
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 0.391931
PMPCA peptidase (mitochondrial processing) alpha 0.390799
PAOX polyamine oxidase (exo-N4-amino) 0.390421
ALOX5 arachidonate 5-lipoxygenase 0.389289
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 0.388158
PNMA2 paraneoplastic Ma antigen 2 0.388158
MYOCD myocardin 0.387404
EGLN2 egl-9 family hypoxia-inducible factor 2 0.384766
FGF1 fibroblast growth factor 1 (acidic) 0.384013
FTL ferritin, light polypeptide 0.38326
FBXL20 F-box and leucine-rich repeat protein 20 0.381379
APLNR apelin receptor 0.380251
AOC2 amine oxidase, copper containing 2 (retina-specific) 0.379499
GCH1 GTP cyclohydrolase 1 0.378372
VIPR1 vasoactive intestinal peptide receptor 1 0.377996
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.377621
GJA4 gap junction protein, alpha 4, 37kDa 0.377245
FTH1 ferritin, heavy polypeptide 1 0.376119
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.373868
CD59 CD59 molecule, complement regulatory protein 0.373493
ACTB actin, beta 0.372743
PTH parathyroid hormone 0.367502
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.367129
CASR calcium-sensing receptor 0.366381
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 0.36302
AGTR1 angiotensin II receptor, type 1 0.361155
NOTCH3 notch 3 0.359292
IGLV1-36 immunoglobulin lambda variable 1-36 0.358174
GRP gastrin-releasing peptide 0.35743
BMP7 bone morphogenetic protein 7 0.357058
FKBP1A FK506 binding protein 1A, 12kDa 0.356314
VMAC vimentin-type intermediate filament associated coiled-coil protein 0.35557
ANXA5 annexin A5 0.354826
TRPC5 transient receptor potential cation channel, subfamily C, member 5 0.354826
STIM1 stromal interaction molecule 1 0.354455
LPAR4 lysophosphatidic acid receptor 4 0.352969
ANO4 anoctamin 4 0.352227
NOX1 NADPH oxidase 1 0.351856
JAG1 jagged 1 0.34926
TNNC2 troponin C type 2 (fast) 0.347038
IL1A interleukin 1, alpha 0.345558
PXN paxillin 0.344079
COL5A3 collagen, type V, alpha 3 0.34334
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.34334
MIR190A microRNA 190a 0.342602
LOXL2 lysyl oxidase-like 2 0.342602
KDR kinase insert domain receptor 0.340757
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.338914
CXCL12 chemokine (C-X-C motif) ligand 12 0.33744
DUOX2 dual oxidase 2 0.337072
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.337072
DUOX1 dual oxidase 1 0.335233
GATA4 GATA binding protein 4 0.328994
TXNL4B thioredoxin-like 4B 0.32753
ACE2 angiotensin I converting enzyme 2 0.327164
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) 0.327164
VCL vinculin 0.325335
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.324605
ICK intestinal cell (MAK-like) kinase 0.324239
JMJD6 jumonji domain containing 6 0.324239
ZNF74 zinc finger protein 74 0.324239
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.323874
AIRE autoimmune regulator 0.323509
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.322779
ANO2 anoctamin 2, calcium activated chloride channel 0.322414
NPTXR neuronal pentraxin receptor 0.32132
INSC inscuteable homolog (Drosophila) 0.320591
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.31877
CYS1 cystin 1 0.317315
LOXL1 lysyl oxidase-like 1 0.316224
EED embryonic ectoderm development 0.315861
LATS2 large tumor suppressor kinase 2 0.313683
SPHK1 sphingosine kinase 1 0.31332
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.312595
SMAD4 SMAD family member 4 0.312232
HRH1 histamine receptor H1 0.310783
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.310783
NOTCH4 notch 4 0.308974
RCC2 regulator of chromosome condensation 2 0.308612
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 0.308612
SPP1 secreted phosphoprotein 1 0.306805
MMD monocyte to macrophage differentiation-associated 0.306805
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.306083
ADRA1D adrenoceptor alpha 1D 0.305722
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.304279
COX5A cytochrome c oxidase subunit Va 0.304279
NPR3 natriuretic peptide receptor 3 0.302838
CCDC34 coiled-coil domain containing 34 0.300679
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.299601
HMGA2 high mobility group AT-hook 2 0.293508
GNA14 guanine nucleotide binding protein (G protein), alpha 14 0.291008
PROS1 protein S (alpha) 0.289582
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 0.289226
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.288158
RYR1 ryanodine receptor 1 (skeletal) 0.286381
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.284607
LBX2 ladybird homeobox 2 0.284607
GJA1 gap junction protein, alpha 1, 43kDa 0.283899
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.282837
LIG3 ligase III, DNA, ATP-dependent 0.280012
GIN1 gypsy retrotransposon integrase 1 0.279659
CD68 CD68 molecule 0.279307
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.278603
CD4 CD4 molecule 0.275444
ADRB1 adrenoceptor beta 1 0.275444
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.275094
ARL15 ADP-ribosylation factor-like 15 0.272997
ICMT isoprenylcysteine carboxyl methyltransferase 0.272649
GJA5 gap junction protein, alpha 5, 40kDa 0.2723
REXO2 RNA exonuclease 2 0.271256
BCHE butyrylcholinesterase 0.270561
ADORA2A adenosine A2a receptor 0.270561
CALCRL calcitonin receptor-like 0.270561
DSTN destrin (actin depolymerizing factor) 0.270561
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.269521
C6ORF25 chromosome 6 open reading frame 25 0.268482
LPAR2 lysophosphatidic acid receptor 2 0.268482
DNM2 dynamin 2 0.267791
PRCP prolylcarboxypeptidase (angiotensinase C) 0.267102
FAM155B family with sequence similarity 155, member B 0.266069
CAPN2 calpain 2, (m/II) large subunit 0.263327
ECI1 enoyl-CoA delta isomerase 1 0.261964
HES5 hes family bHLH transcription factor 5 0.260945
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.260606
KCNK13 potassium channel, two pore domain subfamily K, member 13 0.258243
CLIC3 chloride intracellular channel 3 0.254902
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.253908
CALCB calcitonin-related polypeptide beta 0.253248
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.252919
ATF6 activating transcription factor 6 0.251934
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.251279
PER1 period circadian clock 1 0.250627
KCNK10 potassium channel, two pore domain subfamily K, member 10 0.250627
CSHL1 chorionic somatomammotropin hormone-like 1 0.250627
ALPPL2 alkaline phosphatase, placental-like 2 0.250301
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.249977
ALPL alkaline phosphatase, liver/bone/kidney 0.249653
KCNK4 potassium channel, two pore domain subfamily K, member 4 0.249329
ALPP alkaline phosphatase, placental 0.249006
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.247719
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.246442
PDE9A phosphodiesterase 9A 0.244545
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.240826
ESR1 estrogen receptor 1 0.24052
KLF6 Kruppel-like factor 6 0.239007
KIF1B kinesin family member 1B 0.23781
HTRA2 HtrA serine peptidase 2 0.237216
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.235457
AMT aminomethyltransferase 0.234016
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.234016
TGFBR3 transforming growth factor, beta receptor III 0.234016
SLC36A3 solute carrier family 36, member 3 0.233446
WAPAL wings apart-like homolog (Drosophila) 0.233162
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.232881
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.232039
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.23176
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.230656
FLT1 fms-related tyrosine kinase 1 0.230656
FLNA filamin A, alpha 0.230382
RBMS1 RNA binding motif, single stranded interacting protein 1 0.228764
MFAP4 microfibrillar-associated protein 4 0.228497
IL10 interleukin 10 0.227707
BCL2L1 BCL2-like 1 0.227707
FOS FBJ murine osteosarcoma viral oncogene homolog 0.225395
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.225395
PRRC2A proline-rich coiled-coil 2A 0.223662
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 0.223177
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.223177
WSB1 WD repeat and SOCS box containing 1 0.222224
POMC proopiomelanocortin 0.222224
BCAS2 breast carcinoma amplified sequence 2 0.221755
GCM2 glial cells missing homolog 2 (Drosophila) 0.221291
PPT1 palmitoyl-protein thioesterase 1 0.220831
MMP13 matrix metallopeptidase 13 0.220604
UTS2R urotensin 2 receptor 0.219928
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.219928
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.219928
TPRG1L tumor protein p63 regulated 1-like 0.219707
HDAC9 histone deacetylase 9 0.219264
ASIC1 acid sensing (proton gated) ion channel 1 0.219264
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.218613
GATA6 GATA binding protein 6 0.218186
ESAM endothelial cell adhesion molecule 0.217762
P2RY11 purinergic receptor P2Y, G-protein coupled, 11 0.21673
PPAN-P2RY11 PPAN-P2RY11 readthrough 0.21673
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.216126
CBS cystathionine-beta-synthase 0.215928
CNOT2 CCR4-NOT transcription complex, subunit 2 0.21573
EXTL1 exostosin-like glycosyltransferase 1 0.215534
MAPK8 mitogen-activated protein kinase 8 0.215534
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.215341
PPA2 pyrophosphatase (inorganic) 2 0.215341
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.214388
MIRLET7B microRNA let-7b 0.214017
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.213833
HYAL1 hyaluronoglucosaminidase 1 0.213833
GZMM granzyme M (lymphocyte met-ase 1) 0.213833
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.212413
LIPN lipase, family member N 0.197141
CTNND1 catenin (cadherin-associated protein), delta 1 0.19598
F2RL2 coagulation factor II (thrombin) receptor-like 2 0.195674
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 0.195607
PLD2 phospholipase D2 0.194297
GDF2 growth differentiation factor 2 0.19415
SPHK2 sphingosine kinase 2 0.193993
CLIC4 chloride intracellular channel 4 0.193846
CORO1B coronin, actin binding protein, 1B 0.193292
RIN2 Ras and Rab interactor 2 0.19244
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 0.192131
OAZ1 ornithine decarboxylase antizyme 1 0.192098
BMP6 bone morphogenetic protein 6 0.191015
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.190717
BBX bobby sox homolog (Drosophila) 0.190594
MARCKS myristoylated alanine-rich protein kinase C substrate 0.190157
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.190152
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa 0.190099
OGG1 8-oxoguanine DNA glycosylase 0.189659
XG Xg blood group 0.189166
HBP1 HMG-box transcription factor 1 0.188594
DNASE1 deoxyribonuclease I 0.188553
CCL11 chemokine (C-C motif) ligand 11 0.188461
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 0.188331
DAPK3 death-associated protein kinase 3 0.188199
IQGAP1 IQ motif containing GTPase activating protein 1 0.18804
USP1 ubiquitin specific peptidase 1 0.187558
HOXD8 homeobox D8 0.187479
BET1 Bet1 golgi vesicular membrane trafficking protein 0.187479
HOXD1 homeobox D1 0.187234
RCN1 reticulocalbin 1, EF-hand calcium binding domain 0.187101
NAMPT nicotinamide phosphoribosyltransferase 0.186516
SEBOX SEBOX homeobox 0.186287
MAPK13 mitogen-activated protein kinase 13 0.185644
MARCKSL1 MARCKS-like 1 0.185384
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.18531
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 0.185111
NOXA1 NADPH oxidase activator 1 0.184703
PLA2G5 phospholipase A2, group V 0.184465
PLAU plasminogen activator, urokinase 0.184457
PTPRD protein tyrosine phosphatase, receptor type, D 0.184146
NOX3 NADPH oxidase 3 0.184086
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.184063
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.18331
GPR4 G protein-coupled receptor 4 0.183286
MAPK10 mitogen-activated protein kinase 10 0.183116
HOXD3 homeobox D3 0.182525
HOXD4 homeobox D4 0.182457
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.182301
VDAC2 voltage-dependent anion channel 2 0.181958
CNGA2 cyclic nucleotide gated channel alpha 2 0.181652
DCTN2 dynactin 2 (p50) 0.181606
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.181458
LPCAT3 lysophosphatidylcholine acyltransferase 3 0.181187
RAP2B RAP2B, member of RAS oncogene family 0.180646
RAB1B RAB1B, member RAS oncogene family 0.180617
SAR1A secretion associated, Ras related GTPase 1A 0.180478
ARF3 ADP-ribosylation factor 3 0.180388
LAMA5 laminin, alpha 5 0.180093
ASS1 argininosuccinate synthase 1 0.179771
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.179707
CCL26 chemokine (C-C motif) ligand 26 0.17919
CCL13 chemokine (C-C motif) ligand 13 0.178902
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.178561
PCDH8 protocadherin 8 0.177807
MIR100 microRNA 100 0.177771
COL18A1 collagen, type XVIII, alpha 1 0.177734
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.177588
KAT5 K(lysine) acetyltransferase 5 0.176304
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.175965
BCAM basal cell adhesion molecule (Lutheran blood group) 0.175813
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.175772
MIR21 microRNA 21 0.175577
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.175534
ERF Ets2 repressor factor 0.175435
CCL27 chemokine (C-C motif) ligand 27 0.175421
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.174696
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.174058
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.17346
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.172181
DCD dermcidin 0.171331
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.170985
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.170117
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.169944
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.169087
ARHGAP35 Rho GTPase activating protein 35 0.168657
IGFBP4 insulin-like growth factor binding protein 4 0.168067
ARSB arylsulfatase B 0.167524
TXNDC9 thioredoxin domain containing 9 0.167503
RAMP2 receptor (G protein-coupled) activity modifying protein 2 0.166539
RNH1 ribonuclease/angiogenin inhibitor 1 0.166005
LTA4H leukotriene A4 hydrolase 0.165744
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 0.165021
BEST4 bestrophin 4 0.164774
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.163506
BMPR1B bone morphogenetic protein receptor, type IB 0.161501
ACOT7 acyl-CoA thioesterase 7 0.161332
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 0.160819
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 0.160297
CAMTA1 calmodulin binding transcription activator 1 0.159942
SP100 SP100 nuclear antigen 0.159942
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 0.159131
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.158883
IPO7 importin 7 0.157468
LOXL3 lysyl oxidase-like 3 0.157372
ALOX15B arachidonate 15-lipoxygenase, type B 0.157015
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 0.156554
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.155988
OAZ2 ornithine decarboxylase antizyme 2 0.15575
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.155716
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.154999
PDE4C phosphodiesterase 4C, cAMP-specific 0.154894
LOXL4 lysyl oxidase-like 4 0.154613
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.154054
ANO6 anoctamin 6 0.153982
ANO5 anoctamin 5 0.153332
MIRLET7D microRNA let-7d 0.153224
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.150598
CFL2 cofilin 2 (muscle) 0.149496
FXYD1 FXYD domain containing ion transport regulator 1 0.148932
KLF5 Kruppel-like factor 5 (intestinal) 0.14804
CRIP1 cysteine-rich protein 1 (intestinal) 0.146533
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 0.146061
CCL24 chemokine (C-C motif) ligand 24 0.145286
MIR15B microRNA 15b 0.144229
MIR17 microRNA 17 0.144008
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.143329
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.142559
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.141071
ACOT13 acyl-CoA thioesterase 13 0.141071
ANXA1 annexin A1 0.140262
ACVR2A activin A receptor, type IIA 0.139642
IL13RA2 interleukin 13 receptor, alpha 2 0.139594
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.139203
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.138764
SGPL1 sphingosine-1-phosphate lyase 1 0.138716
NONO non-POU domain containing, octamer-binding 0.13698
ENDOG endonuclease G 0.136681
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.135864
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.134366
CREB1 cAMP responsive element binding protein 1 0.134314
SCN1B sodium channel, voltage gated, type I beta subunit 0.134262
CFL1 cofilin 1 (non-muscle) 0.133843
LGALS1 lectin, galactoside-binding, soluble, 1 0.133687
KLF2 Kruppel-like factor 2 0.132945
NT5C1A 5'-nucleotidase, cytosolic IA 0.132624
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.132624
CTSG cathepsin G 0.13257
ESRRA estrogen-related receptor alpha 0.132464
PARP1 poly (ADP-ribose) polymerase 1 0.132464
TLN1 talin 1 0.132143
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.131983
HDAC6 histone deacetylase 6 0.131769
TMOD4 tropomodulin 4 (muscle) 0.131442
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 0.131388
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.131115
PTEN phosphatase and tensin homolog 0.130732
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 0.130351
RDX radixin 0.129968
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.129187
MAP2K4 mitogen-activated protein kinase kinase 4 0.128742
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.128408
HMBS hydroxymethylbilane synthase 0.128408
KRT75 keratin 75, type II 0.128183
CTBP1 C-terminal binding protein 1 0.128183
GAS6 growth arrest-specific 6 0.128183
MKL1 megakaryoblastic leukemia (translocation) 1 0.127955
THBS1 thrombospondin 1 0.127955
HPX hemopexin 0.127785
XCL1 chemokine (C motif) ligand 1 0.127728
METAP2 methionyl aminopeptidase 2 0.1275
SGK1 serum/glucocorticoid regulated kinase 1 0.127444
TGM1 transglutaminase 1 0.12716
SP3 Sp3 transcription factor 0.126933
TLK2 tousled-like kinase 2 0.126706
PROCR protein C receptor, endothelial 0.126706
CLCNKB chloride channel, voltage-sensitive Kb 0.126478
ATR ATR serine/threonine kinase 0.126478
BCL2 B-cell CLL/lymphoma 2 0.126072
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.125956
FLNC filamin C, gamma 0.125377
MCM8 minichromosome maintenance complex component 8 0.125204
CXCR2 chemokine (C-X-C motif) receptor 2 0.124915
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.124506
MCL1 myeloid cell leukemia 1 0.124388
S100A11 S100 calcium binding protein A11 0.123798
LSR lipolysis stimulated lipoprotein receptor 0.123563
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.123327
AATF apoptosis antagonizing transcription factor 0.123209
ZHX2 zinc fingers and homeoboxes 2 0.122796
RORA RAR-related orphan receptor A 0.122616
MSN moesin 0.122496
MAP2K3 mitogen-activated protein kinase kinase 3 0.122436
CDK2 cyclin-dependent kinase 2 0.122316
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.122256
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 0.122196
PYCR1 pyrroline-5-carboxylate reductase 1 0.122076
VDAC1 voltage-dependent anion channel 1 0.122016
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.121776
AXL AXL receptor tyrosine kinase 0.121237
TNS1 tensin 1 0.120936
PRTN3 proteinase 3 0.120875
BDKRB1 bradykinin receptor B1 0.120631
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.120448
TF transferrin 0.120021
POU2F3 POU class 2 homeobox 3 0.119717
CDC42 cell division cycle 42 0.119656
EPO erythropoietin 0.119473
RGMB repulsive guidance molecule family member b 0.119473
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.118861
ITGB4 integrin, beta 4 0.118799
HOXA1 homeobox A1 0.118427
RAB1A RAB1A, member RAS oncogene family 0.117994
CDX1 caudal type homeobox 1 0.116939
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 0.116687
HYAL2 hyaluronoglucosaminidase 2 0.116687