psychosis Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A condition characterized by changes of personality and thought patterns often accompanied by hallucinations and delusional beliefs. (Human Phenotype Ontology, HP_0000709)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0000709
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Genes

319 genes associated with the psychosis phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
SLCO1B1 solute carrier organic anion transporter family, member 1B1 1.3807
MEIS2 Meis homeobox 2 1.24751
COL27A1 collagen, type XXVII, alpha 1 1.19958
ADGRV1 adhesion G protein-coupled receptor V1 1.19958
PDE4D phosphodiesterase 4D, cAMP-specific 1.18704
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 1.17192
EHF ets homologous factor 1.16661
SPOPL speckle-type POZ protein-like 1.15352
SOX5 SRY (sex determining region Y)-box 5 1.15352
SLC26A9 solute carrier family 26 (anion exchanger), member 9 1.15352
FHOD3 formin homology 2 domain containing 3 1.15352
RNF144A ring finger protein 144A 1.12851
COL21A1 collagen, type XXI, alpha 1 1.12851
CLMN calmin (calponin-like, transmembrane) 1.12851
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 1.11203
ASTN2 astrotactin 2 1.11203
PPA2 pyrophosphatase (inorganic) 2 1.09906
ZNF202 zinc finger protein 202 1.09906
CNTNAP5 contactin associated protein-like 5 1.08774
PPARD peroxisome proliferator-activated receptor delta 1.08774
ATF7IP2 activating transcription factor 7 interacting protein 2 1.0674
TRIM9 tripartite motif containing 9 1.05869
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 1.04365
CDH13 cadherin 13 1.04365
SHISA9 shisa family member 9 1.00059
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 1.00059
MCC mutated in colorectal cancers 1.00059
NALCN sodium leak channel, non selective 0.969142
PVT1 Pvt1 oncogene (non-protein coding) 0.969142
KIRREL3 kin of IRRE like 3 (Drosophila) 0.969142
TRPM1 transient receptor potential cation channel, subfamily M, member 1 0.969142
PRRC2A proline-rich coiled-coil 2A 0.942765
AGBL1 ATP/GTP binding protein-like 1 0.942765
MARC2 mitochondrial amidoxime reducing component 2 0.899912
PHEX phosphate regulating endopeptidase homolog, X-linked 0.899912
POLR3B polymerase (RNA) III (DNA directed) polypeptide B 0.899912
ZNF831 zinc finger protein 831 0.882984
FGGY FGGY carbohydrate kinase domain containing 0.882984
TRIM44 tripartite motif containing 44 0.868241
ELMO1 engulfment and cell motility 1 0.777194
RGS6 regulator of G-protein signaling 6 0.763536
JADE2 jade family PHD finger 2 0.705692
SENP7 SUMO1/sentrin specific peptidase 7 0.696021
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.683395
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.664442
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 0.652869
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.648376
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.646119
MBP myelin basic protein 0.640092
STYX serine/threonine/tyrosine interacting protein 0.637775
CCDC40 coiled-coil domain containing 40 0.632198
TANK TRAF family member-associated NFKB activator 0.631549
MTUS1 microtubule associated tumor suppressor 1 0.625067
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.606387
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.597506
SYNPR synaptoporin 0.590538
MUC16 mucin 16, cell surface associated 0.588029
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 0.585631
EPHX2 epoxide hydrolase 2, cytoplasmic 0.581623
PTK2B protein tyrosine kinase 2 beta 0.58021
PICALM phosphatidylinositol binding clathrin assembly protein 0.56762
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 0.564644
HDLBP high density lipoprotein binding protein 0.558686
UNC13C unc-13 homolog C (C. elegans) 0.558007
COG6 component of oligomeric golgi complex 6 0.557335
KIAA1217 KIAA1217 0.556012
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.550365
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.549174
ATP9A ATPase, class II, type 9A 0.548586
FOXK2 forkhead box K2 0.544615
ERLEC1 endoplasmic reticulum lectin 1 0.54245
DLC1 DLC1 Rho GTPase activating protein 0.541991
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.540725
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.539488
LOC100507377 uncharacterized LOC100507377 0.53828
AKAP2 A kinase (PRKA) anchor protein 2 0.537883
SEZ6L seizure related 6 homolog (mouse)-like 0.53671
ADCY2 adenylate cyclase 2 (brain) 0.533704
ESRRG estrogen-related receptor gamma 0.532262
LRRK2 leucine-rich repeat kinase 2 0.531556
NKAIN3 Na+/K+ transporting ATPase interacting 3 0.530172
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.529832
EGFL6 EGF-like-domain, multiple 6 0.527209
LEKR1 leucine, glutamate and lysine rich 1 0.526585
TLK1 tousled-like kinase 1 0.525663
BTG4 B-cell translocation gene 4 0.525058
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 0.524758
NIPAL1 NIPA-like domain containing 1 0.524164
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.521572
KDM5A lysine (K)-specific demethylase 5A 0.521572
PSD3 pleckstrin and Sec7 domain containing 3 0.521292
CNTN4 contactin 4 0.521013
LOC100134391 uncharacterized LOC100134391 0.519644
DSCC1 DNA replication and sister chromatid cohesion 1 0.519375
GLIS3 GLIS family zinc finger 3 0.518312
SNX24 sorting nexin 24 0.518049
FAM155A family with sequence similarity 155, member A 0.514254
CERS2 ceramide synthase 2 0.512746
PAIP2B poly(A) binding protein interacting protein 2B 0.510564
LINC00316 long intergenic non-protein coding RNA 316 0.508471
RASGEF1A RasGEF domain family, member 1A 0.506024
FREM1 FRAS1 related extracellular matrix 1 0.505592
GALK2 galactokinase 2 0.504738
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.502058
BCAS4 breast carcinoma amplified sequence 4 0.501261
CSMD1 CUB and Sushi multiple domains 1 0.50065
MLIP muscular LMNA-interacting protein 0.50044
CTPS2 CTP synthase 2 0.500231
LDB3 LIM domain binding 3 0.500023
SIRPA signal-regulatory protein alpha 0.499816
CNTN1 contactin 1 0.498388
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 0.497787
ZBTB16 zinc finger and BTB domain containing 16 0.497193
ANXA10 annexin A10 0.496801
SMAD7 SMAD family member 7 0.494694
BPIFC BPI fold containing family C 0.494506
PAX3 paired box 3 0.493579
CAMKMT calmodulin-lysine N-methyltransferase 0.493579
MED12L mediator complex subunit 12-like 0.492667
BSN bassoon presynaptic cytomatrix protein 0.492128
ARID1B AT rich interactive domain 1B (SWI1-like) 0.492128
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.491771
EDA ectodysplasin A 0.491594
LOC145845 uncharacterized LOC145845 0.491417
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 0.491241
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.489681
NTN1 netrin 1 0.489002
LINGO2 leucine rich repeat and Ig domain containing 2 0.489002
OSMR oncostatin M receptor 0.488666
FAM19A1 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 0.488001
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.486163
TBC1D7 TBC1 domain family, member 7 0.485465
LAYN layilin 0.485119
ASB1 ankyrin repeat and SOCS box containing 1 0.485119
LPO lactoperoxidase 0.484775
LONRF3 LON peptidase N-terminal domain and ring finger 3 0.484775
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 0.484434
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 0.483925
CLEC7A C-type lectin domain family 7, member A 0.483925
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 0.483588
AFAP1L1 actin filament associated protein 1-like 1 0.482756
LOC349160 uncharacterized LOC349160 0.481935
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.481287
LOC284788 uncharacterized LOC284788 0.481126
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.480966
ZNF423 zinc finger protein 423 0.480647
MPO myeloperoxidase 0.479077
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.478922
RBMS1 RNA binding motif, single stranded interacting protein 1 0.477701
LHFPL3 lipoma HMGIC fusion partner-like 3 0.4774
LRP1B low density lipoprotein receptor-related protein 1B 0.475772
GLP2R glucagon-like peptide 2 receptor 0.475047
CNTN5 contactin 5 0.473346
SNTG2 syntrophin, gamma 2 0.473346
CMIP c-Maf inducing protein 0.473068
THSD4 thrombospondin, type I, domain containing 4 0.473068
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 0.472653
CA10 carbonic anhydrase X 0.470969
TRAK1 trafficking protein, kinesin binding 1 0.470822
SNTG1 syntrophin, gamma 1 0.470529
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.470093
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.468803
KCNIP4 Kv channel interacting protein 4 0.468099
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.467959
FAM179B family with sequence similarity 179, member B 0.467403
RPS15A ribosomal protein S15a 0.467403
NAV2 neuron navigator 2 0.467264
TRAM2 translocation associated membrane protein 2 0.466851
BCAS1 breast carcinoma amplified sequence 1 0.466578
FAM124B family with sequence similarity 124B 0.465362
SPAG16 sperm associated antigen 16 0.465095
C12ORF42 chromosome 12 open reading frame 42 0.46417
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.463909
OSBPL10 oxysterol binding protein-like 10 0.463519
PDGFRL platelet-derived growth factor receptor-like 0.463003
TENM2 teneurin transmembrane protein 2 0.462746
AGBL4 ATP/GTP binding protein-like 4 0.462619
MEF2C myocyte enhancer factor 2C 0.462364
DGKB diacylglycerol kinase, beta 90kDa 0.462364
CAPS2 calcyphosine 2 0.460983
CLEC4A C-type lectin domain family 4, member A 0.460612
VILL villin-like 0.459755
MAST4 microtubule associated serine/threonine kinase family member 4 0.459633
AGR3 anterior gradient 3 0.459271
ANO7 anoctamin 7 0.45796
SEPT2 septin 2 0.457491
VWA8 von Willebrand factor A domain containing 8 0.457258
PCLO piccolo presynaptic cytomatrix protein 0.455991
ADGRF3 adhesion G protein-coupled receptor F3 0.455764
ARHGAP15 Rho GTPase activating protein 15 0.455538
COL23A1 collagen, type XXIII, alpha 1 0.45496
LINC01588 long intergenic non-protein coding RNA 1588 0.453259
DNAI2 dynein, axonemal, intermediate chain 2 0.452924
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.452813
MDN1 MDN1, midasin homolog (yeast) 0.452482
GALM galactose mutarotase (aldose 1-epimerase) 0.452371
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 0.451933
ZDHHC14 zinc finger, DHHC-type containing 14 0.45021
DLG2 discs, large homolog 2 (Drosophila) 0.449998
LOC643339 uncharacterized LOC643339 0.449892
CLECL1 C-type lectin-like 1 0.449787
LOC100288181 uncharacterized LOC100288181 0.449576
PRICKLE2 prickle homolog 2 (Drosophila) 0.449576
RELN reelin 0.44895
SH3GL2 SH3-domain GRB2-like 2 0.448742
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 0.448433
GAS6 growth arrest-specific 6 0.44792
SGMS1 sphingomyelin synthase 1 0.44711
ANO4 anoctamin 4 0.44711
HDAC9 histone deacetylase 9 0.446709
CCDC12 coiled-coil domain containing 12 0.446709
ANXA9 annexin A9 0.446709
AKAP6 A kinase (PRKA) anchor protein 6 0.446709
ESRRB estrogen-related receptor beta 0.44562
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans) 0.444647
KLHL3 kelch-like family member 3 0.444454
MACROD2 MACRO domain containing 2 0.444263
LOC100506446 uncharacterized LOC100506446 0.443407
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.443407
FGF14 fibroblast growth factor 14 0.443312
ZNF816 zinc finger protein 816 0.443124
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.44303
SLC35F1 solute carrier family 35, member F1 0.442937
CFAP58 cilia and flagella associated protein 58 0.442656
STK31 serine/threonine kinase 31 0.442378
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.441916
VTI1A vesicle transport through interaction with t-SNAREs 1A 0.441732
GORASP2 golgi reassembly stacking protein 2, 55kDa 0.441549
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1 0.441549
WDSUB1 WD repeat, sterile alpha motif and U-box domain containing 1 0.441275
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.440732
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.440642
COL6A2 collagen, type VI, alpha 2 0.440463
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.440194
ITGA9 integrin, alpha 9 0.440194
NTM neurotrimin 0.439838
MTUS2 microtubule associated tumor suppressor candidate 2 0.439661
TSHZ2 teashirt zinc finger homeobox 2 0.438815
MORN5 MORN repeat containing 5 0.438588
CLSTN2 calsyntenin 2 0.438438
SH3TC2 SH3 domain and tetratricopeptide repeats 2 0.438138
VWC2L von Willebrand factor C domain containing protein 2-like 0.438138
ZNF681 zinc finger protein 681 0.437766
GLG1 golgi glycoprotein 1 0.437543
PUM1 pumilio RNA-binding family member 1 0.43747
CNTNAP2 contactin associated protein-like 2 0.436956
LINC00583 long intergenic non-protein coding RNA 583 0.436737
AMPD3 adenosine monophosphate deaminase 3 0.436231
RHOA ras homolog family member A 0.436016
AKAP13 A kinase (PRKA) anchor protein 13 0.435944
EXOC4 exocyst complex component 4 0.435944
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.435873
FHIT fragile histidine triad 0.435873
FAM19A4 family with sequence similarity 19 (chemokine (C-C motif)-like), member A4 0.435873
GRM7 glutamate receptor, metabotropic 7 0.435659
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.435375
ADD1 adducin 1 (alpha) 0.435163
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.434952
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.434952
LPP LIM domain containing preferred translocation partner in lipoma 0.434048
AFF3 AF4/FMR2 family, member 3 0.434048
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.433911
RAB3C RAB3C, member RAS oncogene family 0.433773
LINC01550 long intergenic non-protein coding RNA 1550 0.433705
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.433636
CCDC146 coiled-coil domain containing 146 0.433568
ATRNL1 attractin-like 1 0.433568
SECISBP2L SECIS binding protein 2-like 0.4335
ZNF365 zinc finger protein 365 0.432823
ACVR1 activin A receptor, type I 0.432288
KDM4D lysine (K)-specific demethylase 4D 0.432288
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.432288
RBM45 RNA binding motif protein 45 0.432155
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.432023
PRKCH protein kinase C, eta 0.43189
SPPL3 signal peptide peptidase like 3 0.431627
ROR2 receptor tyrosine kinase-like orphan receptor 2 0.43143
EPB41 erythrocyte membrane protein band 4.1 0.431365
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 0.431235
ADGRG1 adhesion G protein-coupled receptor G1 0.430975
TSPAN9 tetraspanin 9 0.430975
SYK spleen tyrosine kinase 0.43091
SLC38A1 solute carrier family 38, member 1 0.430845
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2 0.430652
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 0.430523
SP100 SP100 nuclear antigen 0.430395
ZNF638 zinc finger protein 638 0.430267
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.430203
ACYP2 acylphosphatase 2, muscle type 0.429949
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.429255
TRDN triadin 0.42808
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.427958
CELF2 CUGBP, Elav-like family member 2 0.427775
PRDM16 PR domain containing 16 0.427714
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 0.427593
DOCK2 dedicator of cytokinesis 2 0.427412
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 0.427412
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 0.427111
TTC39C tetratricopeptide repeat domain 39C 0.426753
DOK6 docking protein 6 0.426753
CRTC3 CREB regulated transcription coactivator 3 0.426634
PCDH9 protocadherin 9 0.426456
KRT4 keratin 4, type II 0.426338
DMD dystrophin 0.426221
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.426181
TEX14 testis expressed 14 0.426021
GDPD4 glycerophosphodiester phosphodiesterase domain containing 4 0.425981
FBN2 fibrillin 2 0.425704
SLC12A8 solute carrier family 12, member 8 0.425311
PRKCE protein kinase C, epsilon 0.425039
RCSD1 RCSD domain containing 1 0.424923
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 0.424807
GPC4 glypican 4 0.424769
MATN2 matrilin 2 0.424654
NRG1 neuregulin 1 0.424616
ANXA6 annexin A6 0.424463
DIO3 deiodinase, iodothyronine, type III 0.424235
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.424197
MRPL19 mitochondrial ribosomal protein L19 0.42416