psoriasis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A skin abnormality characterized by redness and irritation, with thick, red skin that displays flaky, silver-white patches (scales). (Human Phenotype Ontology, HP_0003765)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001193
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Genes

8 gene mutations causing the psoriasis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
IL17C interleukin 17C
IL17RA interleukin 17 receptor A
IL17RE interleukin 17 receptor E
IL1RN interleukin 1 receptor antagonist
IL36RN interleukin 36 receptor antagonist
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
PTPN6 protein tyrosine phosphatase, non-receptor type 6