|Dataset||COMPARTMENTS Curated Protein Localization Evidence Scores|
|Category||structural or functional annotations|
|Description||A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p. (Gene Ontology, GO_0000974)|
|Downloads & Tools|
4 proteins localized to the prp19 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.