primitive neuroectodermal tumor cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description One of a remarkable group of tumors that originate in cells from the primitive neural crest and share the same reciprocal translocation between chromosomes 11 and 22 and the same patterns of biochemical and oncogene expression. Some primitive neuroectodermal tumors (PNETs) occur in the brain while others (the peripheral PNETs) occur in sites outside the brain such as in the extremities, pelvis, and the chest wall. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004258)
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Genes

80 proteins co-occuring with the tissue primitive neuroectodermal tumor cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
EWSR1 EWS RNA-binding protein 1 1.12394
GAB1 GRB2-associated binding protein 1 1.03829
TPCN1 two pore segment channel 1 0.998473
HOXC6 homeobox C6 0.943935
RET ret proto-oncogene 0.931908
HOXB3 homeobox B3 0.903701
PCCA propionyl CoA carboxylase, alpha polypeptide 0.832385
FLI1 Fli-1 proto-oncogene, ETS transcription factor 0.793543
HOXB4 homeobox B4 0.644884
CFLAR CASP8 and FADD-like apoptosis regulator 0.642454
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.637594
GCGR glucagon receptor 0.622639
GLYCTK glycerate kinase 0.564035
FGFR1 fibroblast growth factor receptor 1 0.55607
FAM84B family with sequence similarity 84, member B 0.547922
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.498636
GDNF glial cell derived neurotrophic factor 0.457214
MIR186 microRNA 186 0.456442
S100A4 S100 calcium binding protein A4 0.42993
MMP10 matrix metallopeptidase 10 0.428783
MAPK1 mitogen-activated protein kinase 1 0.424199
PI3 peptidase inhibitor 3, skin-derived 0.412391
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.391176
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.363393
CD177 CD177 molecule 0.35836
TRIB1 tribbles pseudokinase 1 0.356686
KIF1A kinesin family member 1A 0.337072
INSR insulin receptor 0.329727
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.32205
VIPR2 vasoactive intestinal peptide receptor 2 0.321138
SCG2 secretogranin II 0.312232
KIF1B kinesin family member 1B 0.31024
MAP4 microtubule-associated protein 4 0.283545
LGALS4 lectin, galactoside-binding, soluble, 4 0.278251
GRB2 growth factor receptor-bound protein 2 0.257572
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.246124
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.243139
MTSS1 metastasis suppressor 1 0.241592
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.235748
PDGFC platelet derived growth factor C 0.231621
CGB7 chorionic gonadotropin, beta polypeptide 7 0.226283
CGB5 chorionic gonadotropin, beta polypeptide 5 0.225018
RB1 retinoblastoma 1 0.221989
DMBT1 deleted in malignant brain tumors 1 0.220604
CGB chorionic gonadotropin, beta polypeptide 0.22004
CGB8 chorionic gonadotropin, beta polypeptide 8 0.219707
FGFR2 fibroblast growth factor receptor 2 0.217554
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.21673
IGF1R insulin-like growth factor 1 receptor 0.214388
FGF2 fibroblast growth factor 2 (basic) 0.213833
MMP13 matrix metallopeptidase 13 0.21365
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.210369
VEGFB vascular endothelial growth factor B 0.206715
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.205348
CHGB chromogranin B 0.202625
DCXR dicarbonyl/L-xylulose reductase 0.201075
VIPR1 vasoactive intestinal peptide receptor 1 0.199595
MAP1B microtubule-associated protein 1B 0.199032
SFRP1 secreted frizzled-related protein 1 0.198162
NEFM neurofilament, medium polypeptide 0.198033
ENO2 enolase 2 (gamma, neuronal) 0.197808
FHIT fragile histidine triad 0.197522
CHGA chromogranin A 0.19743
TP53 tumor protein p53 0.197299
TNIP1 TNFAIP3 interacting protein 1 0.196924
NEFH neurofilament, heavy polypeptide 0.196865
PIDD1 p53-induced death domain protein 1 0.19634
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.196279
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.196249
NGF nerve growth factor (beta polypeptide) 0.19596
NRG1 neuregulin 1 0.195133
CDKN2A cyclin-dependent kinase inhibitor 2A 0.195016
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.194479
FADD Fas (TNFRSF6)-associated via death domain 0.19393
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.193286
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.192256
GLI1 GLI family zinc finger 1 0.19224
FOS FBJ murine osteosarcoma viral oncogene homolog 0.190524
TGFB3 transforming growth factor, beta 3 0.190271
PDPN podoplanin 0.190172