primidone-5323 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the primidone-5323 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ACTG2 actin, gamma 2, smooth muscle, enteric
AKAP7 A kinase (PRKA) anchor protein 7
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASPH aspartate beta-hydroxylase
ATP9A ATPase, class II, type 9A
ATXN2L ataxin 2-like
BAIAP2 BAI1-associated protein 2
BMP1 bone morphogenetic protein 1
BTBD7 BTB (POZ) domain containing 7
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C19ORF73 chromosome 19 open reading frame 73
CABIN1 calcineurin binding protein 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC85C coiled-coil domain containing 85C
CEP162 centrosomal protein 162kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CIDEB cell death-inducing DFFA-like effector b
CLEC11A C-type lectin domain family 11, member A
CORT cortistatin
CRABP1 cellular retinoic acid binding protein 1
CYHR1 cysteine/histidine-rich 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DOCK1 dedicator of cytokinesis 1
DST dystonin
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EGFR epidermal growth factor receptor
ELOVL5 ELOVL fatty acid elongase 5
EPHA1 EPH receptor A1
EPOR erythropoietin receptor
ERN2 endoplasmic reticulum to nucleus signaling 2
FAXDC2 fatty acid hydroxylase domain containing 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF12 fibroblast growth factor 12
FGFR1 fibroblast growth factor receptor 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAL galanin/GMAP prepropeptide
GRK5 G protein-coupled receptor kinase 5
HIST1H2AJ histone cluster 1, H2aj
HK2 hexokinase 2
HOXA4 homeobox A4
HPS1 Hermansky-Pudlak syndrome 1
IFI6 interferon, alpha-inducible protein 6
INO80D INO80 complex subunit D
ITGB5 integrin, beta 5
JRK Jrk homolog (mouse)
KCTD20 potassium channel tetramerization domain containing 20
KLF4 Kruppel-like factor 4 (gut)
KRIT1 KRIT1, ankyrin repeat containing
KRT17 keratin 17, type I
LYST lysosomal trafficking regulator
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MALT1 MALT1 paracaspase
MBOAT7 membrane bound O-acyltransferase domain containing 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED9 mediator complex subunit 9
MET MET proto-oncogene, receptor tyrosine kinase
MOBP myelin-associated oligodendrocyte basic protein
MXD3 MAX dimerization protein 3
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAAA N-acylethanolamine acid amidase
NDE1 nudE neurodevelopment protein 1
NF1 neurofibromin 1
NOD1 nucleotide-binding oligomerization domain containing 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POU4F1 POU class 4 homeobox 1
PXN paxillin
RECQL5 RecQ protein-like 5
RIOK3 RIO kinase 3
RPL10 ribosomal protein L10
RPL26 ribosomal protein L26
RUFY3 RUN and FYVE domain containing 3
SCN1B sodium channel, voltage gated, type I beta subunit
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT5 sirtuin 5
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPINK5 serine peptidase inhibitor, Kazal type 5
SUGP1 SURP and G patch domain containing 1
SYN2 synapsin II
TBL1Y transducin (beta)-like 1, Y-linked
TMEM63A transmembrane protein 63A
TREX1 three prime repair exonuclease 1
TRIM25 tripartite motif containing 25
TRIM31 tripartite motif containing 31
UBXN1 UBX domain protein 1
ZBTB6 zinc finger and BTB domain containing 6
ZER1 zyg-11 related, cell cycle regulator
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF37BP zinc finger protein 37B, pseudogene
ZNF589 zinc finger protein 589
ZNF710 zinc finger protein 710
ZNF75D zinc finger protein 75D
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACSS3 acyl-CoA synthetase short-chain family member 3
ACVR2A activin A receptor, type IIA
ADCK3 aarF domain containing kinase 3
ADORA2B adenosine A2b receptor
ADPGK ADP-dependent glucokinase
AKR1C3 aldo-keto reductase family 1, member C3
ANKFY1 ankyrin repeat and FYVE domain containing 1
APH1B APH1B gamma secretase subunit
APOD apolipoprotein D
ASB8 ankyrin repeat and SOCS box containing 8
ATG7 autophagy related 7
C14ORF132 chromosome 14 open reading frame 132
C16ORF59 chromosome 16 open reading frame 59
CAMKMT calmodulin-lysine N-methyltransferase
CCDC94 coiled-coil domain containing 94
CDKL3 cyclin-dependent kinase-like 3
CENPT centromere protein T
CHEK2 checkpoint kinase 2
COQ6 coenzyme Q6 monooxygenase
CPTP ceramide-1-phosphate transfer protein
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
GBAS glioblastoma amplified sequence
GLB1L2 galactosidase, beta 1-like 2
GMIP GEM interacting protein
GPR19 G protein-coupled receptor 19
GRWD1 glutamate-rich WD repeat containing 1
GSTM2 glutathione S-transferase mu 2 (muscle)
HIRIP3 HIRA interacting protein 3
IGFLR1 IGF-like family receptor 1
INF2 inverted formin, FH2 and WH2 domain containing
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA0232 KIAA0232
KIAA0894 KIAA0894 protein
KIAA1551 KIAA1551
KIFAP3 kinesin-associated protein 3
KLK6 kallikrein-related peptidase 6
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MKNK2 MAP kinase interacting serine/threonine kinase 2
MLYCD malonyl-CoA decarboxylase
MSX1 msh homeobox 1
MTCL1 microtubule crosslinking factor 1
NBEAL2 neurobeachin-like 2
NPY1R neuropeptide Y receptor Y1
NVL nuclear VCP-like
OPN3 opsin 3
OSMR oncostatin M receptor
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PECR peroxisomal trans-2-enoyl-CoA reductase
PEMT phosphatidylethanolamine N-methyltransferase
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLD3 phospholipase D family, member 3
POMZP3 POM121 and ZP3 fusion
PRR15L proline rich 15-like
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RAI14 retinoic acid induced 14
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RANGRF RAN guanine nucleotide release factor
RBM42 RNA binding motif protein 42
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIBC2 RIB43A domain with coiled-coils 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF113A ring finger protein 113A
RNF123 ring finger protein 123
RPAP2 RNA polymerase II associated protein 2
SCAI suppressor of cancer cell invasion
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SLC38A10 solute carrier family 38, member 10
SMAGP small cell adhesion glycoprotein
SND1-IT1 SND1 intronic transcript 1
SOX12 SRY (sex determining region Y)-box 12
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STX10 syntaxin 10
SYT17 synaptotagmin XVII
SYTL2 synaptotagmin-like 2
TEX30 testis expressed 30
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMOD3 tropomodulin 3 (ubiquitous)
TPST1 tyrosylprotein sulfotransferase 1
TRAPPC12 trafficking protein particle complex 12
TRIM52 tripartite motif containing 52
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTI2 TELO2 interacting protein 2
UBE2O ubiquitin-conjugating enzyme E2O
VWA1 von Willebrand factor A domain containing 1
WDR13 WD repeat domain 13
ZBED1 zinc finger, BED-type containing 1
ZNF14 zinc finger protein 14
ZNF239 zinc finger protein 239
ZNF329 zinc finger protein 329
ZNF331 zinc finger protein 331
ZNF35 zinc finger protein 35
ZNF408 zinc finger protein 408
ZNF571 zinc finger protein 571
ZNF586 zinc finger protein 586
ZNF675 zinc finger protein 675