primidone-3402 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the primidone-3402 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACO2 aconitase 2, mitochondrial
AHSP alpha hemoglobin stabilizing protein
ANXA2P1 annexin A2 pseudogene 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARC activity-regulated cytoskeleton-associated protein
ARR3 arrestin 3, retinal (X-arrestin)
ARTN artemin
ATN1 atrophin 1
ATP10A ATPase, class V, type 10A
ATP11A ATPase, class VI, type 11A
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BARX2 BARX homeobox 2
BGN biglycan
C8A complement component 8, alpha polypeptide
CAPN2 calpain 2, (m/II) large subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCKBR cholecystokinin B receptor
CD1A CD1a molecule
CD300A CD300a molecule
CD47 CD47 molecule
CFAP70 cilia and flagella associated protein 70
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLDN11 claudin 11
CREBZF CREB/ATF bZIP transcription factor
DIAPH2-AS1 DIAPH2 antisense RNA 1
DUSP9 dual specificity phosphatase 9
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ERN2 endoplasmic reticulum to nucleus signaling 2
ESR1 estrogen receptor 1
FKBP5 FK506 binding protein 5
FRMD8 FERM domain containing 8
FRY furry homolog (Drosophila)
FRZB frizzled-related protein
FZD1 frizzled class receptor 1
GATA2 GATA binding protein 2
GLP1R glucagon-like peptide 1 receptor
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPC3 glypican 3
GPR37L1 G protein-coupled receptor 37 like 1
GRM7 glutamate receptor, metabotropic 7
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA1024 KIAA1024
KIAA1467 KIAA1467
KIF25 kinesin family member 25
KLHL25 kelch-like family member 25
LMNA lamin A/C
LTC4S leukotriene C4 synthase
MAU2 MAU2 sister chromatid cohesion factor
MYOF myoferlin
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEU3 sialidase 3 (membrane sialidase)
NOTCH4 notch 4
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OR3A3 olfactory receptor, family 3, subfamily A, member 3
PARD3 par-3 family cell polarity regulator
PDE2A phosphodiesterase 2A, cGMP-stimulated
POFUT1 protein O-fucosyltransferase 1
POU2F2 POU class 2 homeobox 2
PPARD peroxisome proliferator-activated receptor delta
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRLH prolactin releasing hormone
RAD52 RAD52 homolog (S. cerevisiae)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
REC8 REC8 meiotic recombination protein
REEP2 receptor accessory protein 2
RHOH ras homolog family member H
RPH3A rabphilin 3A
RPS4Y1 ribosomal protein S4, Y-linked 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SNCAIP synuclein, alpha interacting protein
SRSF7 serine/arginine-rich splicing factor 7
SSX3 synovial sarcoma, X breakpoint 3
STS steroid sulfatase (microsomal), isozyme S
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYT13 synaptotagmin XIII
TBXA2R thromboxane A2 receptor
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNK1 tyrosine kinase, non-receptor, 1
TP63 tumor protein p63
TRBC1 T cell receptor beta constant 1
TRO trophinin
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TUBB7P tubulin, beta 7, pseudogene
UBA6 ubiquitin-like modifier activating enzyme 6
UTF1 undifferentiated embryonic cell transcription factor 1
ZNF345 zinc finger protein 345
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADM adrenomedullin
ANKH ANKH inorganic pyrophosphate transport regulator
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATAT1 alpha tubulin acetyltransferase 1
BATF basic leucine zipper transcription factor, ATF-like
BLNK B-cell linker
CD83 CD83 molecule
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLGN calmegin
CRIP1 cysteine-rich protein 1 (intestinal)
CXADR coxsackie virus and adenovirus receptor
DGAT1 diacylglycerol O-acyltransferase 1
DLK2 delta-like 2 homolog (Drosophila)
DRD1 dopamine receptor D1
DTX2 deltex 2, E3 ubiquitin ligase
EMCN endomucin
EMID1 EMI domain containing 1
ERO1L ERO1-like (S. cerevisiae)
ETNK2 ethanolamine kinase 2
FAM186A family with sequence similarity 186, member A
FBXO2 F-box protein 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP10 FK506 binding protein 10, 65 kDa
FSCN3 fascin actin-bundling protein 3, testicular
GAS2 growth arrest-specific 2
GAST gastrin
GLRA1 glycine receptor, alpha 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRTP1 growth hormone regulated TBC protein 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HOXC8 homeobox C8
HYAL3 hyaluronoglucosaminidase 3
IFNAR1 interferon (alpha, beta and omega) receptor 1
IMPG2 interphotoreceptor matrix proteoglycan 2
IQSEC2 IQ motif and Sec7 domain 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT83 keratin 83, type II
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LARP6 La ribonucleoprotein domain family, member 6
LIF leukemia inhibitory factor
LOC100131532 uncharacterized LOC100131532
LRRC15 leucine rich repeat containing 15
LYPD1 LY6/PLAUR domain containing 1
MAPK10 mitogen-activated protein kinase 10
MFGE8 milk fat globule-EGF factor 8 protein
NKX3-2 NK3 homeobox 2
NPM3 nucleophosmin/nucleoplasmin 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
NYNRIN NYN domain and retroviral integrase containing
PALM paralemmin
PEX26 peroxisomal biogenesis factor 26
PLXNA3 plexin A3
PODNL1 podocan-like 1
POPDC3 popeye domain containing 3
PTCD2 pentatricopeptide repeat domain 2
RAB40AL RAB40A, member RAS oncogene family-like
RAD54L2 RAD54-like 2 (S. cerevisiae)
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF121 ring finger protein 121
S100A2 S100 calcium binding protein A2
SAA4 serum amyloid A4, constitutive
SAYSD1 SAYSVFN motif domain containing 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC16A4 solute carrier family 16, member 4
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLPI secretory leukocyte peptidase inhibitor
SPEG SPEG complex locus
SPINK4 serine peptidase inhibitor, Kazal type 4
SPON2 spondin 2, extracellular matrix protein
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TBC1D2 TBC1 domain family, member 2
TBKBP1 TBK1 binding protein 1
TH tyrosine hydroxylase
TMEM254 transmembrane protein 254
TMEM260 transmembrane protein 260
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TSGA10 testis specific, 10
UPK2 uroplakin 2
XYLT1 xylosyltransferase I
ZDHHC11 zinc finger, DHHC-type containing 11
ZFHX2 zinc finger homeobox 2
ZNF10 zinc finger protein 10
ZNF134 zinc finger protein 134
ZNF286A zinc finger protein 286A
ZNF37BP zinc finger protein 37B, pseudogene
ZNF432 zinc finger protein 432
ZNF510 zinc finger protein 510
ZNF639 zinc finger protein 639
ZNF668 zinc finger protein 668