presynaptic membrane Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane. (Gene Ontology, GO_0042734)
External Link http://amigo.geneontology.org/amigo/term/GO:0042734
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Genes

57 proteins localized to the presynaptic membrane cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
ADORA1 adenosine A1 receptor
CADPS2 Ca++-dependent secretion activator 2
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CNTNAP4 contactin associated protein-like 4
DENND1A DENN/MADD domain containing 1A
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERC2 ELKS/RAB6-interacting/CAST family member 2
FBXO45 F-box protein 45
FOSL1 FOS-like antigen 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GPER1 G protein-coupled estrogen receptor 1
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIK3 glutamate receptor, ionotropic, kainate 3
GRIK4 glutamate receptor, ionotropic, kainate 4
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRM2 glutamate receptor, metabotropic 2
GRM3 glutamate receptor, metabotropic 3
GRM4 glutamate receptor, metabotropic 4
GRM6 glutamate receptor, metabotropic 6
GRM7 glutamate receptor, metabotropic 7
GRM8 glutamate receptor, metabotropic 8
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KCTD12 potassium channel tetramerization domain containing 12
KCTD16 potassium channel tetramerization domain containing 16
KCTD8 potassium channel tetramerization domain containing 8
L1CAM L1 cell adhesion molecule
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC4B leucine rich repeat containing 4B
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
NLGN2 neuroligin 2
NPTN neuroplastin
NRXN1 neurexin 1
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
PCDH8 protocadherin 8
PDE2A phosphodiesterase 2A, cGMP-stimulated
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PICALM phosphatidylinositol binding clathrin assembly protein
PICK1 protein interacting with PRKCA 1
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RIMS1 regulating synaptic membrane exocytosis 1
RIMS2 regulating synaptic membrane exocytosis 2
SCRIB scribbled planar cell polarity protein
SNAP25 synaptosomal-associated protein, 25kDa
SNCAIP synuclein, alpha interacting protein
SNPH syntaphilin
SYP synaptophysin
SYT1 synaptotagmin I
UNC13A unc-13 homolog A (C. elegans)
UNC13C unc-13 homolog C (C. elegans)
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase
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