prefoldin complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. (Gene Ontology, GO_0016272)
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9 proteins localized to the prefoldin complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PFDN2 prefoldin subunit 2 0.663342
PFDN6 prefoldin subunit 6 0.663342
URI1 URI1, prefoldin-like chaperone 0.03318
UXT ubiquitously-expressed, prefoldin-like chaperone 0.03318
PFDN1 prefoldin subunit 1 0.03318
PFDN5 prefoldin subunit 5 0.03318
PFDN4 prefoldin subunit 4 0.03318
PDRG1 p53 and DNA-damage regulated 1 0.03318
VBP1 von Hippel-Lindau binding protein 1 0.03318