prednisone-4577 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the prednisone-4577 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACAN aggrecan
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADCK2 aarF domain containing kinase 2
ADGRA2 adhesion G protein-coupled receptor A2
ADGRG6 adhesion G protein-coupled receptor G6
AFAP1 actin filament associated protein 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AK5 adenylate kinase 5
AKAP9 A kinase (PRKA) anchor protein 9
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARTN artemin
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C10ORF10 chromosome 10 open reading frame 10
CAMKMT calmodulin-lysine N-methyltransferase
CCND2 cyclin D2
CDH8 cadherin 8, type 2
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEMIP cell migration inducing protein, hyaluronan binding
CEP135 centrosomal protein 135kDa
CLCN4 chloride channel, voltage-sensitive 4
CNTNAP2 contactin associated protein-like 2
CREM cAMP responsive element modulator
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DENND2A DENN/MADD domain containing 2A
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ELK1 ELK1, member of ETS oncogene family
ESRRG estrogen-related receptor gamma
ETV1 ets variant 1
FAM63B family with sequence similarity 63, member B
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FRZB frizzled-related protein
GIF gastric intrinsic factor (vitamin B synthesis)
GPR85 G protein-coupled receptor 85
GUSBP3 glucuronidase, beta pseudogene 3
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICOSLG inducible T-cell co-stimulator ligand
ILF3 interleukin enhancer binding factor 3, 90kDa
KDM4C lysine (K)-specific demethylase 4C
KDM6B lysine (K)-specific demethylase 6B
KDM8 lysine (K)-specific demethylase 8
KLF3 Kruppel-like factor 3 (basic)
KRIT1 KRIT1, ankyrin repeat containing
KRT6A keratin 6A, type II
LARGE like-glycosyltransferase
LIPG lipase, endothelial
MAP1B microtubule-associated protein 1B
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MEGF6 multiple EGF-like-domains 6
MMP3 matrix metallopeptidase 3
MRPL41 mitochondrial ribosomal protein L41
MYO1D myosin ID
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NTF3 neurotrophin 3
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHGA8 protocadherin gamma subfamily A, 8
PHF14 PHD finger protein 14
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PITX1 paired-like homeodomain 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PQBP1 polyglutamine binding protein 1
PRKG1 protein kinase, cGMP-dependent, type I
PTK6 protein tyrosine kinase 6
RASAL2 RAS protein activator like 2
RCAN1 regulator of calcineurin 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RFWD3 ring finger and WD repeat domain 3
RIN3 Ras and Rab interactor 3
SIAH1 siah E3 ubiquitin protein ligase 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SOAT1 sterol O-acyltransferase 1
SS18 synovial sarcoma translocation, chromosome 18
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
SUMO1 small ubiquitin-like modifier 1
TBC1D4 TBC1 domain family, member 4
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCF4 transcription factor 4
TFEB transcription factor EB
THBS1 thrombospondin 1
TIMELESS timeless circadian clock
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNPO2 transportin 2
TOR1AIP1 torsin A interacting protein 1
TRD T cell receptor delta locus
TTC33 tetratricopeptide repeat domain 33
UBA6 ubiquitin-like modifier activating enzyme 6
UBR2 ubiquitin protein ligase E3 component n-recognin 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VPRBP Vpr (HIV-1) binding protein
WSB1 WD repeat and SOCS box containing 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YTHDC2 YTH domain containing 2
ZCCHC11 zinc finger, CCHC domain containing 11
ZNF286A zinc finger protein 286A

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ADGRB2 adhesion G protein-coupled receptor B2
ADGRG2 adhesion G protein-coupled receptor G2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BNC1 basonuclin 1
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C1R complement component 1, r subcomponent
CASZ1 castor zinc finger 1
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDON cell adhesion associated, oncogene regulated
CHRDL1 chordin-like 1
CLCA1 chloride channel accessory 1
CNN1 calponin 1, basic, smooth muscle
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DEPTOR DEP domain containing MTOR-interacting protein
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DMTN dematin actin binding protein
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELSPBP1 epididymal sperm binding protein 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPN3 epsin 3
F3 coagulation factor III (thromboplastin, tissue factor)
FAM53B family with sequence similarity 53, member B
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FGF13 fibroblast growth factor 13
FKBP1B FK506 binding protein 1B, 12.6 kDa
GDAP1 ganglioside induced differentiation associated protein 1
GPX2 glutathione peroxidase 2
HIST1H1D histone cluster 1, H1d
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BM histone cluster 1, H2bm
HIST1H2BN histone cluster 1, H2bn
HIST1H3C histone cluster 1, H3c
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DMA major histocompatibility complex, class II, DM alpha
IFNA14 interferon, alpha 14
IL17RB interleukin 17 receptor B
IL2 interleukin 2
INCENP inner centromere protein antigens 135/155kDa
KIAA1107 KIAA1107
KLHL3 kelch-like family member 3
KRT86 keratin 86, type II
LINC00115 long intergenic non-protein coding RNA 115
LOC257152 uncharacterized LOC257152
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MRPL52 mitochondrial ribosomal protein L52
MRPS18C mitochondrial ribosomal protein S18C
MYO19 myosin XIX
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEUROD4 neuronal differentiation 4
NINJ1 ninjurin 1
NKX3-2 NK3 homeobox 2
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NYNRIN NYN domain and retroviral integrase containing
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G15 phospholipase A2, group XV
PLA2G1B phospholipase A2, group IB (pancreas)
PNP purine nucleoside phosphorylase
PRF1 perforin 1 (pore forming protein)
PROX1 prospero homeobox 1
PRSS53 protease, serine, 53
RAB4B RAB4B, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF126P1 ring finger protein 126 pseudogene 1
RUSC2 RUN and SH3 domain containing 2
SCGB2A2 secretoglobin, family 2A, member 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3D21 SH3 domain containing 21
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMA4 glucuronidase, beta pseudogene
STK16 serine/threonine kinase 16
SUGP1 SURP and G patch domain containing 1
TIGD6 tigger transposable element derived 6
TIMP4 TIMP metallopeptidase inhibitor 4
TMSB15A thymosin beta 15a
TUBA3C tubulin, alpha 3c
TWISTNB TWIST neighbor
USP19 ubiquitin specific peptidase 19
VGF VGF nerve growth factor inducible
WDR62 WD repeat domain 62
WNT10B wingless-type MMTV integration site family, member 10B
ZC3H12A zinc finger CCCH-type containing 12A
ZNF10 zinc finger protein 10
ZNF205 zinc finger protein 205
ZNF343 zinc finger protein 343
ZNF415 zinc finger protein 415
ZNF446 zinc finger protein 446
ZNF574 zinc finger protein 574
ZNF747 zinc finger protein 747