pre-autophagosomal structure Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A punctate structure localized in the vicinity of the vacuole that is required for the formation of autophagosomes. (Gene Ontology, GO_0000407)
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Genes

99 proteins co-occuring with the pre-autophagosomal structure cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ULK1 unc-51 like autophagy activating kinase 1 2.38287
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.31846
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 2.02132
WIPI2 WD repeat domain, phosphoinositide interacting 2 1.87796
RB1CC1 RB1-inducible coiled-coil 1 1.72432
ATG12 autophagy related 12 1.72307
ATG5 autophagy related 5 1.6836
ATG14 autophagy related 14 1.56788
UVRAG UV radiation resistance associated 1.36692
ATG101 autophagy related 101 1.31088
ACBD5 acyl-CoA binding domain containing 5 1.2777
ATG2A autophagy related 2A 1.27505
STX17 syntaxin 17 1.27027
ATG3 autophagy related 3 1.26392
ZFYVE1 zinc finger, FYVE domain containing 1 1.20086
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.15876
TECPR1 tectonin beta-propeller repeat containing 1 1.15672
BECN1 beclin 1, autophagy related 1.15109
RAB33B RAB33B, member RAS oncogene family 1.12552
RAB1A RAB1A, member RAS oncogene family 1.1148
NRBF2 nuclear receptor binding factor 2 1.10715
GABARAP GABA(A) receptor-associated protein 1.10154
ATG4B autophagy related 4B, cysteine peptidase 1.02281
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 1.00695
ATG13 autophagy related 13 0.969848
RAB33A RAB33A, member RAS oncogene family 0.969366
NBR1 neighbor of BRCA1 gene 1 0.958789
ATG9A autophagy related 9A 0.933129
ATG16L2 autophagy related 16-like 2 (S. cerevisiae) 0.929833
ULK2 unc-51 like autophagy activating kinase 2 0.907855
ATG7 autophagy related 7 0.847451
SQSTM1 sequestosome 1 0.83781
TBC1D17 TBC1 domain family, member 17 0.825418
KIAA0226 KIAA0226 0.817158
ATG2B autophagy related 2B 0.80523
ASS1 argininosuccinate synthase 1 0.731076
VMP1 vacuole membrane protein 1 0.729732
MTMR14 myotubularin related protein 14 0.716791
TBC1D15 TBC1 domain family, member 15 0.687701
STX12 syntaxin 12 0.661208
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 0.632451
ATG4A autophagy related 4A, cysteine peptidase 0.624355
RALB v-ral simian leukemia viral oncogene homolog B 0.621379
VAMP8 vesicle-associated membrane protein 8 0.607395
SNX18 sorting nexin 18 0.607395
CPNE1 copine I 0.588456
DOK3 docking protein 3 0.555973
NUAK1 NUAK family, SNF1-like kinase, 1 0.544823
TRAPPC2 trafficking protein particle complex 2 0.519798
PDCD1LG2 programmed cell death 1 ligand 2 0.515308
LIN9 lin-9 DREAM MuvB core complex component 0.500664
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.482467
SMOX spermine oxidase 0.472011
CALCOCO2 calcium binding and coiled-coil domain 2 0.464397
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.461199
AMBRA1 autophagy/beclin-1 regulator 1 0.458006
RAB24 RAB24, member RAS oncogene family 0.453223
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.448054
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 0.444482
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.43696
AMPH amphiphysin 0.434985
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.428284
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 0.424745
PI3 peptidase inhibitor 3, skin-derived 0.415728
TRAPPC10 trafficking protein particle complex 10 0.40714
ATG4C autophagy related 4C, cysteine peptidase 0.393162
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 0.391228
TRAPPC9 trafficking protein particle complex 9 0.380045
IGKV3-20 immunoglobulin kappa variable 3-20 0.378891
LGALS8 lectin, galactoside-binding, soluble, 8 0.375434
CYTH1 cytohesin 1 0.372749
PEG3 paternally expressed 3 0.360515
TARS threonyl-tRNA synthetase 0.352901
MEOX2 mesenchyme homeobox 2 0.326453
GABARAPL1 GABA(A) receptor-associated protein like 1 0.319328
TNK2 tyrosine kinase, non-receptor, 2 0.315212
MAP4 microtubule-associated protein 4 0.28846
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.284032
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 0.277406
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 0.268237
CHMP2B charged multivesicular body protein 2B 0.261296
BRWD1 bromodomain and WD repeat domain containing 1 0.231315
PEX6 peroxisomal biogenesis factor 6 0.231315
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.224558
PEX3 peroxisomal biogenesis factor 3 0.215761
PAOX polyamine oxidase (exo-N4-amino) 0.214366
GCG glucagon 0.213322
OPTN optineurin 0.207794
PEX1 peroxisomal biogenesis factor 1 0.206423
RFXANK regulatory factor X-associated ankyrin-containing protein 0.199993
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 0.198991
MAP2 microtubule-associated protein 2 0.193719
IGF2R insulin-like growth factor 2 receptor 0.191135
ACPP acid phosphatase, prostate 0.18702
MAPT microtubule-associated protein tau 0.183935
SRPX2 sushi-repeat containing protein, X-linked 2 0.178877
MEA1 male-enhanced antigen 1 0.173814
HSPE1 heat shock 10kDa protein 1 0.166643
TFEB transcription factor EB 0.160863