prc1 complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling. (Gene Ontology, GO_0035102)
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Genes

88 proteins co-occuring with the prc1 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PRC1 protein regulator of cytokinesis 1 2.99384
BMI1 BMI1 proto-oncogene, polycomb ring finger 2.03651
CBX7 chromobox homolog 7 1.7964
CBX8 chromobox homolog 8 1.5548
CBX2 chromobox homolog 2 1.39796
SCML2 sex comb on midleg-like 2 (Drosophila) 1.3896
RNF2 ring finger protein 2 1.35266
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.35102
RING1 ring finger protein 1 1.33957
CBX4 chromobox homolog 4 1.27399
KDM2B lysine (K)-specific demethylase 2B 1.27346
ASXL1 additional sex combs like transcriptional regulator 1 1.26709
HIST1H2AD histone cluster 1, H2ad 1.25075
HIST1H2AJ histone cluster 1, H2aj 1.25075
HIST1H2AM histone cluster 1, H2am 1.25075
H2AFJ H2A histone family, member J 1.25075
HIST1H2AH histone cluster 1, H2ah 1.25022
HIST1H2AG histone cluster 1, H2ag 1.24865
H2AFY2 H2A histone family, member Y2 1.24655
HIST1H2AE histone cluster 1, H2ae 1.2455
HIST1H2AB histone cluster 1, H2ab 1.2455
H2AFV H2A histone family, member V 1.24498
H2AFB1 H2A histone family, member B1 1.24131
H2AFB2 H2A histone family, member B2 1.23661
H2AFY H2A histone family, member Y 1.23192
PCGF2 polycomb group ring finger 2 1.2288
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 1.22049
L3MBTL2 l(3)mbt-like 2 (Drosophila) 1.15979
CBX6 chromobox homolog 6 1.12245
HIST2H2AC histone cluster 2, H2ac 0.982446
HIST2H2AA4 histone cluster 2, H2aa4 0.981959
HIST2H2AA3 histone cluster 2, H2aa3 0.981959
RYBP RING1 and YY1 binding protein 0.909716
PCGF1 polycomb group ring finger 1 0.863068
MTF2 metal response element binding transcription factor 2 0.845155
E2F6 E2F transcription factor 6 0.837351
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.723919
H3F3B H3 histone, family 3B (H3.3B) 0.719906
H3F3A H3 histone, family 3A 0.719906
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.706156
PCGF6 polycomb group ring finger 6 0.695148
KIF20B kinesin family member 20B 0.676803
PHC1 polyhomeotic homolog 1 (Drosophila) 0.676368
YAF2 YY1 associated factor 2 0.664664
NMRAL1 NmrA-like family domain containing 1 0.640573
CDKN2A cyclin-dependent kinase inhibitor 2A 0.631171
PHC3 polyhomeotic homolog 3 (Drosophila) 0.612895
ZFP42 ZFP42 zinc finger protein 0.60655
PHC2 polyhomeotic homolog 2 (Drosophila) 0.590133
USP11 ubiquitin specific peptidase 11 0.577164
DOT1L DOT1-like histone H3K79 methyltransferase 0.571329
PRMT8 protein arginine methyltransferase 8 0.559285
UIMC1 ubiquitin interaction motif containing 1 0.52716
RUVBL2 RuvB-like AAA ATPase 2 0.501881
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.500664
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.476027
PHF19 PHD finger protein 19 0.465198
EED embryonic ectoderm development 0.464397
MOV10 Mov10 RISC complex RNA helicase 0.439333
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.425924
PARK2 parkin RBR E3 ubiquitin protein ligase 0.416902
SFMBT1 Scm-like with four mbt domains 1 0.408309
SPOP speckle-type POZ protein 0.397423
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 0.38428
BCOR BCL6 corepressor 0.341907
ASCL2 achaete-scute family bHLH transcription factor 2 0.340773
TWIST1 twist family bHLH transcription factor 1 0.32195
HOXC13 homeobox C13 0.317456
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.281453
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.277774
NANOG Nanog homeobox 0.253291
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.252202
JARID2 jumonji, AT rich interactive domain 2 0.251114
BRCA1 breast cancer 1, early onset 0.246769
STRA8 stimulated by retinoic acid 8 0.242437
EGLN2 egl-9 family hypoxia-inducible factor 2 0.241356
SETD7 SET domain containing (lysine methyltransferase) 7 0.239197
KDM6A lysine (K)-specific demethylase 6A 0.227397
KLF4 Kruppel-like factor 4 (gut) 0.209513
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.200663
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.200663
YY1 YY1 transcription factor 0.199325
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.189857
HDAC7 histone deacetylase 7 0.187646
MNX1 motor neuron and pancreas homeobox 1 0.180339
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.171673
PRMT2 protein arginine methyltransferase 2 0.168598
KMT2B lysine (K)-specific methyltransferase 2B 0.166643