postsynaptic density Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description The postsynaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases. The postsynaptic density may be part of a neuron or a muscle cell or a glial cell. (Gene Ontology, GO_0014069)
External Link http://amigo.geneontology.org/amigo/term/GO:0014069
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130 proteins localized to the postsynaptic density cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
ABI1 abl-interactor 1
ACTB actin, beta
ADAM10 ADAM metallopeptidase domain 10
ADD1 adducin 1 (alpha)
ADORA1 adenosine A1 receptor
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ARC activity-regulated cytoskeleton-associated protein
ARF1 ADP-ribosylation factor 1
ARHGAP32 Rho GTPase activating protein 32
ARRB2 arrestin, beta 2
AXIN1 axin 1
AXIN2 axin 2
BCR breakpoint cluster region
BSN bassoon presynaptic cytomatrix protein
CABP1 calcium binding protein 1
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CACNG8 calcium channel, voltage-dependent, gamma subunit 8
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CHRM1 cholinergic receptor, muscarinic 1
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CNIH2 cornichon family AMPA receptor auxiliary protein 2
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPEB4 cytoplasmic polyadenylation element binding protein 4
CRIPT cysteine-rich PDZ-binding protein
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DBNL drebrin-like
DISC1 disrupted in schizophrenia 1
DLG1 discs, large homolog 1 (Drosophila)
DLG2 discs, large homolog 2 (Drosophila)
DLG3 discs, large homolog 3 (Drosophila)
DLG4 discs, large homolog 4 (Drosophila)
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DLGAP3 discs, large (Drosophila) homolog-associated protein 3
DNM2 dynamin 2
DNM3 dynamin 3
DRD2 dopamine receptor D2
DTNBP1 dystrobrevin binding protein 1
EPHA4 EPH receptor A4
EPS8 epidermal growth factor receptor pathway substrate 8
FBXO45 F-box protein 45
FYN FYN proto-oncogene, Src family tyrosine kinase
GAP43 growth associated protein 43
GOPC golgi-associated PDZ and coiled-coil motif containing
GPER1 G protein-coupled estrogen receptor 1
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRM1 glutamate receptor, metabotropic 1
GRM3 glutamate receptor, metabotropic 3
GRM5 glutamate receptor, metabotropic 5
HOMER1 homer scaffolding protein 1
HOMER2 homer scaffolding protein 2
HOMER3 homer scaffolding protein 3
IFNGR1 interferon gamma receptor 1
ITGA8 integrin, alpha 8
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KLHL17 kelch-like family member 17
LIN7A lin-7 homolog A (C. elegans)
LIN7B lin-7 homolog B (C. elegans)
LIN7C lin-7 homolog C (C. elegans)
LRFN1 leucine rich repeat and fibronectin type III domain containing 1
LRP4 low density lipoprotein receptor-related protein 4
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC7 leucine rich repeat containing 7
LYN LYN proto-oncogene, Src family tyrosine kinase
LZTS1 leucine zipper, putative tumor suppressor 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP1B microtubule-associated protein 1B
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MIB1 mindbomb E3 ubiquitin protein ligase 1
MINK1 misshapen-like kinase 1
MPDZ multiple PDZ domain protein
MTMR2 myotubularin related protein 2
NCS1 neuronal calcium sensor 1
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NEURL1 neuralized E3 ubiquitin protein ligase 1
NGFR nerve growth factor receptor
NLGN1 neuroligin 1
NLGN4X neuroligin 4, X-linked
NLGN4Y neuroligin 4, Y-linked
NSF N-ethylmaleimide-sensitive factor
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PCLO piccolo presynaptic cytomatrix protein
PDLIM5 PDZ and LIM domain 5
PICK1 protein interacting with PRKCA 1
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PKP4 plakophilin 4
PLCB4 phospholipase C, beta 4
PSD3 pleckstrin and Sec7 domain containing 3
PTCH1 patched 1
PTK2B protein tyrosine kinase 2 beta
RAB8A RAB8A, member RAS oncogene family
RGS14 regulator of G-protein signaling 14
RUSC1 RUN and SH3 domain containing 1
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SH2D5 SH2 domain containing 5
SHANK1 SH3 and multiple ankyrin repeat domains 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SHARPIN SHANK-associated RH domain interactor
SIPA1L1 signal-induced proliferation-associated 1 like 1
SORCS3 sortilin-related VPS10 domain containing receptor 3
SOS1 son of sevenless homolog 1 (Drosophila)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRCIN1 SRC kinase signaling inhibitor 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STRN striatin, calmodulin binding protein
SYNDIG1 synapse differentiation inducing 1
SYNPO synaptopodin
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta