polymorphonuclear leukocyte Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Any fully developed granular leukocyte whose nucleus contains multiple lobes joined by filamentous connections, especially a neutrophil. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001026)
Similar Terms
Downloads & Tools

Genes

328 proteins co-occuring with the tissue polymorphonuclear leukocyte in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
MPO myeloperoxidase 2.85813
C5AR1 complement component 5a receptor 1 2.55384
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.21826
ELANE elastase, neutrophil expressed 2.12992
GUSB glucuronidase, beta 2.12406
CTSG cathepsin G 2.10219
SOD2 superoxide dismutase 2, mitochondrial 2.02519
CXCL8 chemokine (C-X-C motif) ligand 8 1.99694
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.99321
ALOX5 arachidonate 5-lipoxygenase 1.98843
LYZ lysozyme 1.94935
CAT catalase 1.91642
LTF lactotransferrin 1.90291
TNF tumor necrosis factor 1.87753
ICAM1 intercellular adhesion molecule 1 1.76375
BPI bactericidal/permeability-increasing protein 1.73977
ALB albumin 1.7318
IL1B interleukin 1, beta 1.65357
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.65107
SELL selectin L 1.6146
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 1.59177
KIAA0101 KIAA0101 1.51
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 1.48974
PLA2G1B phospholipase A2, group IB (pancreas) 1.42322
CSN1S1 casein alpha s1 1.40938
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.39467
SELE selectin E 1.39055
FN1 fibronectin 1 1.38963
MMP8 matrix metallopeptidase 8 1.36587
PRTN3 proteinase 3 1.33364
CD79A CD79a molecule, immunoglobulin-associated alpha 1.30118
IL1A interleukin 1, alpha 1.24342
CXCR1 chemokine (C-X-C motif) receptor 1 1.23896
IL6 interleukin 6 1.19711
ALPPL2 alkaline phosphatase, placental-like 2 1.19045
ALPL alkaline phosphatase, liver/bone/kidney 1.18956
ALPP alkaline phosphatase, placental 1.18867
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.16693
CXCR2 chemokine (C-X-C motif) receptor 2 1.16426
CRP C-reactive protein, pentraxin-related 1.15761
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.1421
GABARAP GABA(A) receptor-associated protein 1.13102
MAPK10 mitogen-activated protein kinase 10 1.1142
CTRL chymotrypsin-like 1.07044
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.06868
AZU1 azurocidin 1 1.0339
LTB4R leukotriene B4 receptor 1.03258
MMP9 matrix metallopeptidase 9 1.02337
CD47 CD47 molecule 1.02162
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.01156
CD4 CD4 molecule 1.0085
FPR1 formyl peptide receptor 1 1.00719
C3 complement component 3 1.00632
GPX4 glutathione peroxidase 4 0.992379
GPX5 glutathione peroxidase 5 0.985859
GPX1 glutathione peroxidase 1 0.968955
VCAM1 vascular cell adhesion molecule 1 0.965928
PGLYRP4 peptidoglycan recognition protein 4 0.965928
PTAFR platelet-activating factor receptor 0.944366
HSH2D hematopoietic SH2 domain containing 0.934482
FPR2 formyl peptide receptor 2 0.929764
ACPP acid phosphatase, prostate 0.914361
CCL2 chemokine (C-C motif) ligand 2 0.907109
PML promyelocytic leukemia 0.905831
CFI complement factor I 0.893496
IL10 interleukin 10 0.888405
KNG1 kininogen 1 0.867686
ANXA1 annexin A1 0.865999
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 0.865999
CCL3 chemokine (C-C motif) ligand 3 0.865999
F3 coagulation factor III (thromboplastin, tissue factor) 0.861363
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.85547
NT5E 5'-nucleotidase, ecto (CD73) 0.850005
GPR32 G protein-coupled receptor 32 0.849165
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 0.845385
CFP complement factor properdin 0.842867
SELPLG selectin P ligand 0.820248
LPO lactoperoxidase 0.81983
FTH1 ferritin, heavy polypeptide 1 0.806465
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.802293
FTL ferritin, light polypeptide 0.798958
PGLYRP2 peptidoglycan recognition protein 2 0.793543
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.790628
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.790212
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.788964
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.774419
CTSC cathepsin C 0.7711
IMMT inner membrane protein, mitochondrial 0.766539
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.764468
ADGRG6 adhesion G protein-coupled receptor G6 0.757018
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.754537
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.752884
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.743801
PGLYRP3 peptidoglycan recognition protein 3 0.742152
ESAM endothelial cell adhesion molecule 0.741327
PLG plasminogen 0.733912
RARA retinoic acid receptor, alpha 0.726097
SAG S-antigen; retina and pineal gland (arrestin) 0.724453
TSPO translocator protein (18kDa) 0.720755
HCK HCK proto-oncogene, Src family tyrosine kinase 0.717472
LTA4H leukotriene A4 hydrolase 0.71583
ADA adenosine deaminase 0.712959
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.71009
POLR1A polymerase (RNA) I polypeptide A, 194kDa 0.707631
TLR2 toll-like receptor 2 0.701899
CSF3 colony stimulating factor 3 (granulocyte) 0.699444
MMP2 matrix metallopeptidase 2 0.694946
DEFA3 defensin, alpha 3, neutrophil-specific 0.694537
ARL14 ADP-ribosylation factor-like 14 0.692493
TF transferrin 0.683919
MGAM maltase-glucoamylase 0.681471
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.677395
ALOX12 arachidonate 12-lipoxygenase 0.668843
CXCL2 chemokine (C-X-C motif) ligand 2 0.668436
KRT16 keratin 16, type I 0.666809
FGR FGR proto-oncogene, Src family tyrosine kinase 0.661523
F12 coagulation factor XII (Hageman factor) 0.66071
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.65746
TLR4 toll-like receptor 4 0.656242
TIMP1 TIMP metallopeptidase inhibitor 1 0.644479
IL2 interleukin 2 0.638809
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.63719
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.627485
SEBOX SEBOX homeobox 0.62385
CAMP cathelicidin antimicrobial peptide 0.623043
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.623043
PGLYRP1 peptidoglycan recognition protein 1 0.61699
IL1RN interleukin 1 receptor antagonist 0.61578
PI3 peptidase inhibitor 3, skin-derived 0.614571
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.607319
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.604904
CD59 CD59 molecule, complement regulatory protein 0.603295
THBD thrombomodulin 0.599273
ITGA6 integrin, alpha 6 0.594451
EDN1 endothelin 1 0.594451
EDA ectodysplasin A 0.59405
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.593247
GJB6 gap junction protein, beta 6, 30kDa 0.593247
ANXA5 annexin A5 0.592444
KAT5 K(lysine) acetyltransferase 5 0.590437
LBP lipopolysaccharide binding protein 0.586026
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.581218
LPCAT2 lysophosphatidylcholine acyltransferase 2 0.563637
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.563637
CTSD cathepsin D 0.560449
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.552093
CD68 CD68 molecule 0.551695
ANG angiogenin, ribonuclease, RNase A family, 5 0.546136
NOS2 nitric oxide synthase 2, inducible 0.538604
GYPC glycophorin C (Gerbich blood group) 0.534647
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.533065
CXCL10 chemokine (C-X-C motif) ligand 10 0.531484
CSNK2B casein kinase 2, beta polypeptide 0.520829
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.520829
KLK8 kallikrein-related peptidase 8 0.520435
ACE angiotensin I converting enzyme 0.516104
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.512564
G6PD glucose-6-phosphate dehydrogenase 0.508242
MMP1 matrix metallopeptidase 1 0.499223
EPX eosinophil peroxidase 0.498048
PNN pinin, desmosome associated protein 0.4914
MORC3 MORC family CW-type zinc finger 3 0.490229
A2M alpha-2-macroglobulin 0.489057
INS insulin 0.488667
TAC1 tachykinin, precursor 1 0.487106
MAK16 MAK16 homolog (S. cerevisiae) 0.485545
SLPI secretory leukocyte peptidase inhibitor 0.48087
CXCL5 chemokine (C-X-C motif) ligand 5 0.479702
F2 coagulation factor II (thrombin) 0.478145
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 0.476979
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.471927
CYBB cytochrome b-245, beta polypeptide 0.469987
LTC4S leukotriene C4 synthase 0.469211
IL4 interleukin 4 0.463013
HPX hemopexin 0.454898
PTH parathyroid hormone 0.452198
PYGB phosphorylase, glycogen; brain 0.450271
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.449886
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.449886
PYGL phosphorylase, glycogen, liver 0.449116
STX2 syntaxin 2 0.446422
PYGM phosphorylase, glycogen, muscle 0.444499
ADORA2B adenosine A2b receptor 0.444499
SBDS Shwachman-Bodian-Diamond syndrome 0.440274
SOCS5 suppressor of cytokine signaling 5 0.439507
CRYGN crystallin, gamma N 0.438356
DNAH8 dynein, axonemal, heavy chain 8 0.43414
GSR glutathione reductase 0.432608
THY1 Thy-1 cell surface antigen 0.425726
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 0.42191
C4A complement component 4A (Rodgers blood group) 0.421529
IL17A interleukin 17A 0.416195
RBP3 retinol binding protein 3, interstitial 0.411251
S100A8 S100 calcium binding protein A8 0.410111
MMP7 matrix metallopeptidase 7 0.407832
CFH complement factor H 0.404418
ISPD isoprenoid synthase domain containing 0.400628
CP ceruloplasmin (ferroxidase) 0.397979
IFT122 intraflagellar transport 122 0.396087
CD63 CD63 molecule 0.395709
GALE UDP-galactose-4-epimerase 0.389289
YARS tyrosyl-tRNA synthetase 0.388158
B2M beta-2-microglobulin 0.386273
TGFB1 transforming growth factor, beta 1 0.385143
APCS amyloid P component, serum 0.382131
C5 complement component 5 0.380251
ALOX15 arachidonate 15-lipoxygenase 0.378372
SPEG SPEG complex locus 0.378372
VNN2 vanin 2 0.375368
SPN sialophorin 0.374618
TMEM11 transmembrane protein 11 0.371994
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.368998
S100A9 S100 calcium binding protein A9 0.366007
RNASEH2A ribonuclease H2, subunit A 0.36302
PF4 platelet factor 4 0.360782
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.357802
GSN gelsolin 0.352598
TMSB4X thymosin beta 4, X-linked 0.351856
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.351114
NOS3 nitric oxide synthase 3 (endothelial cell) 0.348148
TTL tubulin tyrosine ligase 0.345558
HDAC7 histone deacetylase 7 0.344449
HP haptoglobin 0.34334
IL2RA interleukin 2 receptor, alpha 0.341495
NPS neuropeptide S 0.341126
TUB tubby bipartite transcription factor 0.340388
GLB1 galactosidase, beta 1 0.340019
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.338545
AADACL3 arylacetamide deacetylase-like 3 0.33744
CCL13 chemokine (C-C motif) ligand 13 0.335968
PLAT plasminogen activator, tissue 0.335233
FASLG Fas ligand (TNF superfamily, member 6) 0.333396
HPR haptoglobin-related protein 0.333028
ADORA2A adenosine A2a receptor 0.333028
GSS glutathione synthetase 0.333028
CADM1 cell adhesion molecule 1 0.328262
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.327164
DUOX2 dual oxidase 2 0.326798
TUBB4B tubulin, beta 4B class IVb 0.326432
PHLDA3 pleckstrin homology-like domain, family A, member 3 0.326067
DUOX1 dual oxidase 1 0.32497
HBA2 hemoglobin, alpha 2 0.323509
IL2RG interleukin 2 receptor, gamma 0.319498
CTSS cathepsin S 0.319134
TRIM37 tripartite motif containing 37 0.309697
MAMDC4 MAM domain containing 4 0.307528
MMP25 matrix metallopeptidase 25 0.303198
CD44 CD44 molecule (Indian blood group) 0.302838
CFD complement factor D (adipsin) 0.300679
MYLK myosin light chain kinase 0.298524
NEUROD1 neuronal differentiation 1 0.297806
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.296372
XDH xanthine dehydrogenase 0.296013
VWF von Willebrand factor 0.291365
C2 complement component 2 0.289226
SYK spleen tyrosine kinase 0.286026
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.285316
CCL4 chemokine (C-C motif) ligand 4 0.283899
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.283191
PRF1 perforin 1 (pore forming protein) 0.277197
IL15 interleukin 15 0.275444
POMC proopiomelanocortin 0.274045
CERK ceramide kinase 0.270909
PARP1 poly (ADP-ribose) polymerase 1 0.270561
GPR176 G protein-coupled receptor 176 0.269521
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.269521
CMKLR1 chemerin chemokine-like receptor 1 0.268828
HBA1 hemoglobin, alpha 1 0.268482
SRXN1 sulfiredoxin 1 0.265038
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.264011
SNN stannin 0.263327
CTSB cathepsin B 0.263327
CD14 CD14 molecule 0.261964
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.260606
TIMP2 TIMP metallopeptidase inhibitor 2 0.259929
CD19 CD19 molecule 0.258243
HMOX1 heme oxygenase 1 0.256234
PFN4 profilin family, member 4 0.255234
PTGFRN prostaglandin F2 receptor inhibitor 0.253908
POR P450 (cytochrome) oxidoreductase 0.253248
HYDIN HYDIN, axonemal central pair apparatus protein 0.25259
CCR1 chemokine (C-C motif) receptor 1 0.251279
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.250627
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.249006
CD46 CD46 molecule, complement regulatory protein 0.249006
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.247399
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 0.246124
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.245807
IFNA1 interferon, alpha 1 0.244232
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.242363
TP53 tumor protein p53 0.241746
DDIT4L DNA-damage-inducible transcript 4-like 0.23961
FABP9 fatty acid binding protein 9, testis 0.23961
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.23961
TBXA2R thromboxane A2 receptor 0.237513
LMAN1 lectin, mannose-binding, 1 0.236332
KLK11 kallikrein-related peptidase 11 0.23604
HRH1 histamine receptor H1 0.234878
PFKM phosphofructokinase, muscle 0.232881
TSKU tsukushi, small leucine rich proteoglycan 0.23176
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.231206
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.230382
OPN3 opsin 3 0.229839
DNTT DNA nucleotidylexotransferase 0.229299
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 0.229032
LAP3 leucine aminopeptidase 3 0.229032
CTSE cathepsin E 0.227186
LUM lumican 0.2259
MMP26 matrix metallopeptidase 26 0.223419
TBXAS1 thromboxane A synthase 1 (platelet) 0.222699
CCL23 chemokine (C-C motif) ligand 23 0.222699
CLCN3 chloride channel, voltage-sensitive 3 0.22246
HK3 hexokinase 3 (white cell) 0.22246
HK1 hexokinase 1 0.221521
NXT1 nuclear transport factor 2-like export factor 1 0.221061
MAPT microtubule-associated protein tau 0.219485
PFN2 profilin 2 0.218398
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.218186
TLR9 toll-like receptor 9 0.217139
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.216528
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.216528
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 0.216126
PTGES prostaglandin E synthase 0.215534
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.215534
PFN1 profilin 1 0.215341
RNPS1 RNA binding protein S1, serine-rich domain 0.214388
PTPRC protein tyrosine phosphatase, receptor type, C 0.212936
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.212761