polyketide synthase complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones. (Gene Ontology, GO_0034081)
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Genes

161 proteins co-occuring with the polyketide synthase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 3.01463
OXSM 3-oxoacyl-ACP synthase, mitochondrial 2.50731
FASN fatty acid synthase 2.07287
PROK2 prokineticin 2 1.82863
ARMC1 armadillo repeat containing 1 1.53105
ACP6 acid phosphatase 6, lysophosphatidic 1.45138
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 1.39461
KARS lysyl-tRNA synthetase 1.2708
ARAF A-Raf proto-oncogene, serine/threonine kinase 1.24498
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 1.22776
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 1.20292
PROK1 prokineticin 1 1.19623
ACP5 acid phosphatase 5, tartrate resistant 1.13369
MCEE methylmalonyl CoA epimerase 1.03679
LLPH LLP homolog, long-term synaptic facilitation (Aplysia) 1.03629
CDAN1 codanin 1 1.03428
PKLR pyruvate kinase, liver and RBC 1.01734
PKM pyruvate kinase, muscle 1.00843
MED12 mediator complex subunit 12 1.00399
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 0.987317
CYCS cytochrome c, somatic 0.96792
KLHL25 kelch-like family member 25 0.956395
FBXO38 F-box protein 38 0.948284
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 0.838269
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.814405
COASY CoA synthase 0.802479
POLD2 polymerase (DNA directed), delta 2, accessory subunit 0.801104
FDXR ferredoxin reductase 0.785529
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.784614
AKNA AT-hook transcription factor 0.696026
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.684644
TEX2 testis expressed 2 0.673762
OXSR1 oxidative stress responsive 1 0.666827
PKDCC protein kinase domain containing, cytoplasmic 0.64915
AFM afamin 0.632024
TOX thymocyte selection-associated high mobility group box 0.629465
PROKR1 prokineticin receptor 1 0.606973
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.60655
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.584686
PRAMEF9 PRAME family member 9 0.580922
GLYATL1 glycine-N-acyltransferase-like 1 0.578416
FAM132A family with sequence similarity 132, member A 0.57008
SLITRK1 SLIT and NTRK-like family, member 1 0.569664
PCDHGA10 protocadherin gamma subfamily A, 10 0.546885
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.54194
PRAMEF12 PRAME family member 12 0.536183
MUT methylmalonyl CoA mutase 0.528388
PAGE5 P antigen family, member 5 (prostate associated) 0.52716
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 0.522659
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.518981
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 0.518165
PSD pleckstrin and Sec7 domain containing 0.515308
ACP1 acid phosphatase 1, soluble 0.50635
CFC1 cripto, FRL-1, cryptic family 1 0.505944
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.505537
CDK18 cyclin-dependent kinase 18 0.486904
NACA nascent polypeptide-associated complex alpha subunit 0.471609
MTFMT mitochondrial methionyl-tRNA formyltransferase 0.470406
NANS N-acetylneuraminic acid synthase 0.465198
CALN1 calneuron 1 0.461998
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.455613
SCOC short coiled-coil protein 0.455613
OTC ornithine carbamoyltransferase 0.436565
CHKA choline kinase alpha 0.435775
TNRC6A trinucleotide repeat containing 6A 0.433801
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.421997
PPP3R2 protein phosphatase 3, regulatory subunit B, beta 0.415337
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 0.414164
CSNK2B casein kinase 2, beta polypeptide 0.410649
ACP2 acid phosphatase 2, lysosomal 0.409479
BLM Bloom syndrome, RecQ helicase-like 0.405582
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 0.404026
MRS2 MRS2 magnesium transporter 0.402859
SLURP1 secreted LY6/PLAUR domain containing 1 0.401693
SLK STE20-like kinase 0.399751
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.396648
ATAD3C ATPase family, AAA domain containing 3C 0.39626
ORM1 orosomucoid 1 0.380814
CSN1S1 casein alpha s1 0.370833
NMT1 N-myristoyltransferase 1 0.363567
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.36204
FA2H fatty acid 2-hydroxylase 0.357847
ALB albumin 0.354422
PKN2 protein kinase N2 0.348725
FBXO7 F-box protein 7 0.337751
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.333979
LCN1 lipocalin 1 0.332848
IL18RAP interleukin 18 receptor accessory protein 0.324576
FKBP1A FK506 binding protein 1A, 12kDa 0.314839
SOS2 son of sevenless homolog 2 (Drosophila) 0.311105
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.307004
GPS2 G protein pathway suppressor 2 0.306632
ZNF79 zinc finger protein 79 0.305888
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.305515
LMLN leishmanolysin-like (metallopeptidase M8 family) 0.305143
CC2D2A coiled-coil and C2 domain containing 2A 0.29994
RIOK2 RIO kinase 2 0.294007
RRM1 ribonucleotide reductase M1 0.284769
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.284401
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 0.27998
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.277038
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.2719
PPT1 palmitoyl-protein thioesterase 1 0.268969
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 0.264946
RTN4R reticulon 4 receptor 0.264215
EDC3 enhancer of mRNA decapping 3 0.26385
APEH acylaminoacyl-peptide hydrolase 0.26239
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.258016
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 0.256197
MGAM maltase-glucoamylase 0.255107
PTGDR2 prostaglandin D2 receptor 2 0.253653
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.253291
IGH immunoglobulin heavy locus 0.252202
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.248578
EGFR epidermal growth factor receptor 0.247492
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.247492
NLN neurolysin (metallopeptidase M3 family) 0.244962
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.244601
SGCE sarcoglycan, epsilon 0.233101
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.230958
STYK1 serine/threonine/tyrosine kinase 1 0.229888
EPHA7 EPH receptor A7 0.229888
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.213322
POMP proteasome maturation protein 0.212974
BLVRB biliverdin reductase B 0.21124
HYLS1 hydrolethalus syndrome 1 0.210203
IARS isoleucyl-tRNA synthetase 0.209169
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.208481
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.206082
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.20574
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.204718
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.204039
HOXA1 homeobox A1 0.202346
MET MET proto-oncogene, receptor tyrosine kinase 0.200663
DPEP1 dipeptidase 1 (renal) 0.199659
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.196999
STK25 serine/threonine kinase 25 0.19307
DSG1 desmoglein 1 0.185777
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.184853
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.184853
COPA coatomer protein complex, subunit alpha 0.184241
PSCA prostate stem cell antigen 0.183935
CSF3 colony stimulating factor 3 (granulocyte) 0.182723
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.182122
PGLS 6-phosphogluconolactonase 0.181524
RSPO1 R-spondin 1 0.174087
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.173273
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 0.171937
DRD3 dopamine receptor D3 0.169604
OAZ1 ornithine decarboxylase antizyme 1 0.168598
CABIN1 calcineurin binding protein 1 0.168101
PRLH prolactin releasing hormone 0.165932
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 0.164089
TXNL1 thioredoxin-like 1 0.163865
CA1 carbonic anhydrase I 0.162763
SENP1 SUMO1/sentrin specific peptidase 1 0.162117
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.159658
RPGR retinitis pigmentosa GTPase regulator 0.140971
ERBB3 erb-b2 receptor tyrosine kinase 3 0.139904
MTM1 myotubularin 1 0.139393
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.136234