pole plasm Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo. (Gene Ontology, GO_0045495)
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Genes

244 proteins co-occuring with the pole plasm cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 1.89316
SRA1 steroid receptor RNA activator 1 1.77144
PIWIL1 piwi-like RNA-mediated gene silencing 1 1.57188
TDRD1 tudor domain containing 1 1.55991
NANOS1 nanos homolog 1 (Drosophila) 1.52766
TDRD7 tudor domain containing 7 1.44177
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 1.41138
CHMP2A charged multivesicular body protein 2A 1.35758
TDRD5 tudor domain containing 5 1.34392
STAU1 staufen double-stranded RNA binding protein 1 1.31843
PIWIL4 piwi-like RNA-mediated gene silencing 4 1.31681
NANOS3 nanos homolog 3 (Drosophila) 1.2476
BRIX1 BRX1, biogenesis of ribosomes 1.19365
GRIP2 glutamate receptor interacting protein 2 1.16799
BOLL boule-like RNA-binding protein 1.14443
DAZL deleted in azoospermia-like 1.12909
TEF thyrotrophic embryonic factor 1.11072
TDRD9 tudor domain containing 9 1.05387
GYPE glycophorin E (MNS blood group) 1.04733
MAEL maelstrom spermatogenic transposon silencer 1.02929
SUB1 SUB1 homolog (S. cerevisiae) 0.993183
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 0.95305
TDRD6 tudor domain containing 6 0.943059
CST7 cystatin F (leukocystatin) 0.927013
SRSF10 serine/arginine-rich splicing factor 10 0.925135
ZNF644 zinc finger protein 644 0.921854
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.90646
ENO3 enolase 3 (beta, muscle) 0.905531
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 0.902281
TES testin LIM domain protein 0.899962
EIF4E eukaryotic translation initiation factor 4E 0.890245
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.876869
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.869966
EXD2 exonuclease 3'-5' domain containing 2 0.864447
TDRKH tudor and KH domain containing 0.857555
HIATL1 hippocampus abundant transcript-like 1 0.827254
GBX1 gastrulation brain homeobox 1 0.827254
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 0.797895
TMEM259 transmembrane protein 259 0.785071
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.739614
NSUN5 NOP2/Sun domain family, member 5 0.73018
TRIM36 tripartite motif containing 36 0.703507
ANKRD49 ankyrin repeat domain 49 0.698223
GMCL1 germ cell-less, spermatogenesis associated 1 0.689451
CLP1 cleavage and polyadenylation factor I subunit 1 0.67246
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.665962
DND1 DND microRNA-mediated repression inhibitor 1 0.643572
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.635868
FADS3 fatty acid desaturase 3 0.625206
GLI1 GLI family zinc finger 1 0.621379
PDE1B phosphodiesterase 1B, calmodulin-dependent 0.621379
POLR1C polymerase (RNA) I polypeptide C, 30kDa 0.616285
PCDHGA10 protocadherin gamma subfamily A, 10 0.615861
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 0.615437
PRMT5 protein arginine methyltransferase 5 0.599381
FANCD2 Fanconi anemia, complementation group D2 0.595173
POC1A POC1 centriolar protein A 0.594332
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 0.593492
TMEM11 transmembrane protein 11 0.591812
PGM3 phosphoglucomutase 3 0.588037
TCL1B T-cell leukemia/lymphoma 1B 0.587618
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.583849
MAGOHB mago-nashi homolog B (Drosophila) 0.58134
ZNRD1 zinc ribbon domain containing 1 0.580504
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.575495
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.575495
BRSK1 BR serine/threonine kinase 1 0.570913
CSN1S1 casein alpha s1 0.568832
ALLC allantoicase 0.560943
ALG3 ALG3, alpha-1,3- mannosyltransferase 0.560943
MON2 MON2 homolog (S. cerevisiae) 0.5568
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 0.554318
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 0.551838
LOX lysyl oxidase 0.544
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.538649
MAGEE1 melanoma antigen family E1 0.530847
DCP1A decapping mRNA 1A 0.52225
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) 0.518573
TRIM44 tripartite motif containing 44 0.516532
BATF2 basic leucine zipper transcription factor, ATF-like 2 0.503912
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.497826
HN1L hematological and neurological expressed 1-like 0.493775
SSPN sarcospan 0.486904
CER1 cerberus 1, DAN family BMP antagonist 0.484483
NOL9 nucleolar protein 9 0.482467
FBXO44 F-box protein 44 0.478843
PODN podocan 0.47442
PRG1 p53-responsive gene 1 0.465598
CAPN1 calpain 1, (mu/I) large subunit 0.462798
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.457606
GYLTL1B glycosyltransferase-like 1B 0.45641
NME1-NME2 NME1-NME2 readthrough 0.452427
MGAM maltase-glucoamylase 0.451631
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.447656
WNT11 wingless-type MMTV integration site family, member 11 0.446069
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 0.444878
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 0.444482
PGD phosphogluconate dehydrogenase 0.442896
FADS2 fatty acid desaturase 2 0.43696
FOXG1 forkhead box G1 0.432618
RPLP1 ribosomal protein, large, P1 0.432618
MYB v-myb avian myeloblastosis viral oncogene homolog 0.428678
KRTAP1-3 keratin associated protein 1-3 0.425531
ELOVL5 ELOVL fatty acid elongase 5 0.421997
LRRC25 leucine rich repeat containing 25 0.420036
ZAR1 zygote arrest 1 0.413382
MEI1 meiosis inhibitor 1 0.404026
KIN Kin17 DNA and RNA binding protein 0.404026
FAF2 Fas associated factor family member 2 0.401304
RBM8A RNA binding motif protein 8A 0.397811
SYN3 synapsin III 0.395873
AKTIP AKT interacting protein 0.393936
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.393549
GDF11 growth differentiation factor 11 0.390455
PPCS phosphopantothenoylcysteine synthetase 0.390068
ABI3 ABI family, member 3 0.389296
DAZ2 deleted in azoospermia 2 0.387751
GGT2 gamma-glutamyltransferase 2 0.386979
DAZ1 deleted in azoospermia 1 0.385051
KIF13B kinesin family member 13B 0.383895
KRTAP1-1 keratin associated protein 1-1 0.382739
BIN2 bridging integrator 2 0.381199
TPRG1L tumor protein p63 regulated 1-like 0.37966
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.37966
WDR77 WD repeat domain 77 0.379276
VIT vitrin 0.379276
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 0.37697
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.373132
ANGPTL6 angiopoietin-like 6 0.369684
PDCD11 programmed cell death 11 0.364331
DPEP1 dipeptidase 1 (renal) 0.358609
THUMPD1 THUMP domain containing 1 0.357467
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.357086
EPRS glutamyl-prolyl-tRNA synthetase 0.355183
NOP2 NOP2 nucleolar protein 0.354042
SPEG SPEG complex locus 0.353662
FST follistatin 0.352901
PGM1 phosphoglucomutase 1 0.352522
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 0.352142
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 0.346071
KRT84 keratin 84, type II 0.345314
RGMB repulsive guidance molecule family member b 0.343799
BIN3 bridging integrator 3 0.342664
TMC1 transmembrane channel-like 1 0.336241
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 0.330966
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.330589
AXIN2 axin 2 0.328708
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 0.326078
GFRA1 GDNF family receptor alpha 1 0.324576
PRM1 protamine 1 0.318205
MATK megakaryocyte-associated tyrosine kinase 0.311851
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.309613
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.304027
VRK1 vaccinia related kinase 1 0.300311
CPEB1 cytoplasmic polyadenylation element binding protein 1 0.299569
FEV FEV (ETS oncogene family) 0.298455
DICER1 dicer 1, ribonuclease type III 0.293267
DLK1 delta-like 1 homolog (Drosophila) 0.290678
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.289569
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.285138
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.282189
XRN1 5'-3' exoribonuclease 1 0.281085
RTN3 reticulon 3 0.275569
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.273734
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.273367
PNMA1 paraneoplastic Ma antigen 1 0.272633
ANTXR2 anthrax toxin receptor 2 0.271167
FOXH1 forkhead box H1 0.271167
TUBB2A tubulin, beta 2A class IIa 0.2708
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.26385
TECR trans-2,3-enoyl-CoA reductase 0.26239
A2M alpha-2-macroglobulin 0.26239
WDR20 WD repeat domain 20 0.256925
CIRBP cold inducible RNA binding protein 0.256561
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.249302
MIER1 mesoderm induction early response 1, transcriptional regulator 0.24894
RPL12 ribosomal protein L12 0.246407
CBS cystathionine-beta-synthase 0.243879
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) 0.241716
LRP5 low density lipoprotein receptor-related protein 5 0.238837
AMT aminomethyltransferase 0.23776
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 0.23776
MACF1 microtubule-actin crosslinking factor 1 0.234174
ACP1 acid phosphatase 1, soluble 0.233817
MAST4 microtubule associated serine/threonine kinase family member 4 0.233817
ICT1 immature colon carcinoma transcript 1 0.232744
MMP10 matrix metallopeptidase 10 0.226331
MAT1A methionine adenosyltransferase I, alpha 0.225622
COMT catechol-O-methyltransferase 0.22385
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.22173
ELAVL2 ELAV like neuron-specific RNA binding protein 2 0.220673
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 0.217861
DCP2 decapping mRNA 2 0.216111
CASD1 CAS1 domain containing 1 0.215063
PDS5B PDS5 cohesin associated factor B 0.214366
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.212627
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.211933
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.206423
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.206082
TUBB tubulin, beta class I 0.199993
RAG2 recombination activating gene 2 0.198991
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.198325
MPI mannose phosphate isomerase 0.198325
CAT catalase 0.196999
RHOA ras homolog family member A 0.195681
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 0.195681
ZNF185 zinc finger protein 185 (LIM domain) 0.194045
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.193719
RPL32 ribosomal protein L32 0.189857
FOXL2 forkhead box L2 0.189539
EPGN epithelial mitogen 0.189539
GGT1 gamma-glutamyltransferase 1 0.18859
DEFB1 defensin, beta 1 0.188274
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.18796
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 0.18796
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.18702
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.184853
LPIN1 lipin 1 0.182122
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.180634
MAN2B1 mannosidase, alpha, class 2B, member 1 0.179459
TNP1 transition protein 1 (during histone to protamine replacement) 0.178877
RAP1GAP RAP1 GTPase activating protein 0.178011
NBR1 neighbor of BRCA1 gene 1 0.177439
NMS neuromedin S 0.173814
C6ORF25 chromosome 6 open reading frame 25 0.173003
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.170114
BICD1 bicaudal D homolog 1 (Drosophila) 0.169604
CTSA cathepsin A 0.168101
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.167856
PDCL phosducin-like 0.165697
ACACB acetyl-CoA carboxylase beta 0.165
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.16477
SRR serine racemase 0.164089
RFXANK regulatory factor X-associated ankyrin-containing protein 0.162546
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.161068
RAG1 recombination activating gene 1 0.160053
TUB tubby bipartite transcription factor 0.159074
CWC15 CWC15 spliceosome-associated protein 0.158882
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.158315
ERF Ets2 repressor factor 0.157578
WDR5 WD repeat domain 5 0.157218
PRM2 protamine 2 0.156863
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.135976
TGM4 transglutaminase 4 0.135814