plasma protein metabolism disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An inherited metabolic disorder that involves plasma protein metabolism malfunction. (Human Disease Ontology, DOID_2345)
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Genes

250 genes co-occuring with the disease plasma protein metabolism disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 2.43358
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1.92248
ELANE elastase, neutrophil expressed 1.7396
CD79A CD79a molecule, immunoglobulin-associated alpha 1.73094
ADRA1D adrenoceptor alpha 1D 1.67548
MYD88 myeloid differentiation primary response 88 1.50667
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.46891
TMBIM4 transmembrane BAX inhibitor motif containing 4 1.4566
MAG myelin associated glycoprotein 1.39652
CD5 CD5 molecule 1.38821
CD19 CD19 molecule 1.35158
CD38 CD38 molecule 1.07236
CD22 CD22 molecule 1.04293
ALB albumin 1.02271
B2M beta-2-microglobulin 1.01343
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.975482
IGLV7-43 immunoglobulin lambda variable 7-43 0.973801
PAX5 paired box 5 0.94369
CD27 CD27 molecule 0.934556
IGHV3-74 immunoglobulin heavy variable 3-74 0.932484
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 0.912257
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 0.911022
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 0.887208
SLPI secretory leukocyte peptidase inhibitor 0.867549
IGHV3-64 immunoglobulin heavy variable 3-64 0.865502
BTK Bruton agammaglobulinemia tyrosine kinase 0.852402
PRTN3 proteinase 3 0.846669
IGHV3-13 immunoglobulin heavy variable 3-13 0.836837
IL6 interleukin 6 0.832738
CD52 CD52 molecule 0.832329
PAX2 paired box 2 0.824538
CD79B CD79b molecule, immunoglobulin-associated beta 0.802795
IGHV3-9 immunoglobulin heavy variable 3-9 0.774932
SERPINA13P serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene 0.760639
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 0.758193
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.742735
SRP54 signal recognition particle 54kDa 0.71925
IGHV3-7 immunoglobulin heavy variable 3-7 0.716425
UNK unkempt family zinc finger 0.688692
ATG13 autophagy related 13 0.676706
HLA-G major histocompatibility complex, class I, G 0.671527
CD70 CD70 molecule 0.66199
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.6608
TTR transthyretin 0.65288
CD4 CD4 molecule 0.652089
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.644586
F8 coagulation factor VIII, procoagulant component 0.641827
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 0.631991
IGHV1-2 immunoglobulin heavy variable 1-2 0.610838
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.60264
SYVN1 synovial apoptosis inhibitor 1, synoviolin 0.60108
NEUROD1 neuronal differentiation 1 0.592895
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.592116
HAS1 hyaluronan synthase 1 0.589001
FGFBP2 fibroblast growth factor binding protein 2 0.585108
CRNN cornulin 0.583941
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.579272
CXCR4 chemokine (C-X-C motif) receptor 4 0.566831
IGH immunoglobulin heavy locus 0.561004
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.554791
RPTOR regulatory associated protein of MTOR, complex 1 0.544318
IRAK1 interleukin-1 receptor-associated kinase 1 0.543542
F3 coagulation factor III (thromboplastin, tissue factor) 0.542379
IGHV4-39 immunoglobulin heavy variable 4-39 0.541217
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 0.538506
CRP C-reactive protein, pentraxin-related 0.536183
GGT1 gamma-glutamyltransferase 1 0.525746
HYKK hydroxylysine kinase 0.524202
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.521888
LYZ lysozyme 0.51842
BCLAF1 BCL2-associated transcription factor 1 0.517265
HRAS Harvey rat sarcoma viral oncogene homolog 0.514956
CD40LG CD40 ligand 0.513033
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.501909
SIGLEC10 sialic acid binding Ig-like lectin 10 0.489311
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.481705
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.473361
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 0.465038
GC group-specific component (vitamin D binding protein) 0.46466
HFE hemochromatosis 0.449571
CD40 CD40 molecule, TNF receptor superfamily member 5 0.445052
XBP1 X-box binding protein 1 0.443171
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.442418
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.43753
CBR3 carbonyl reductase 3 0.436026
ATF6 activating transcription factor 6 0.433772
BIRC3 baculoviral IAP repeat containing 3 0.43227
SLC38A4 solute carrier family 38, member 4 0.430017
CXCL9 chemokine (C-X-C motif) ligand 9 0.428891
CAMLG calcium modulating ligand 0.42814
EEF1A1P6 eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 0.42589
VWF von Willebrand factor 0.42289
MALT1 MALT1 paracaspase 0.419517
PRDM1 PR domain containing 1, with ZNF domain 0.414276
ORM2 orosomucoid 2 0.406798
CDA cytidine deaminase 0.388909
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.387423
IGHV5-51 immunoglobulin heavy variable 5-51 0.386679
TF transferrin 0.386308
ADA adenosine deaminase 0.380739
MARCKS myristoylated alanine-rich protein kinase C substrate 0.379256
AFP alpha-fetoprotein 0.378143
UNG uracil-DNA glycosylase 0.373328
HAMP hepcidin antimicrobial peptide 0.366671
CTRL chymotrypsin-like 0.351923
HDAC9 histone deacetylase 9 0.344207
CD59 CD59 molecule, complement regulatory protein 0.338341
MPO myeloperoxidase 0.338341
SAA1 serum amyloid A1 0.337608
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 0.32774
TECR trans-2,3-enoyl-CoA reductase 0.325552
CXCL8 chemokine (C-X-C motif) ligand 8 0.324823
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.324458
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.322273
TP53 tumor protein p53 0.318635
USB1 U6 snRNA biogenesis 1 0.315366
ARID1A AT rich interactive domain 1A (SWI-like) 0.315366
CXXC5 CXXC finger protein 5 0.312827
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.302337
SAA4 serum amyloid A4, constitutive 0.300533
F2 coagulation factor II (thrombin) 0.300173
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.294413
HDAC4 histone deacetylase 4 0.293334
CDR1 cerebellar degeneration-related protein 1, 34kDa 0.291539
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 0.29118
TRAF3 TNF receptor-associated factor 3 0.287593
UNC93B1 unc-93 homolog B1 (C. elegans) 0.284728
IREB2 iron-responsive element binding protein 2 0.270464
GGT2 gamma-glutamyltransferase 2 0.264077
MLX MLX, MAX dimerization protein 0.263014
BCL10 B-cell CLL/lymphoma 10 0.260538
CANX calnexin 0.260184
PIDD1 p53-induced death domain protein 1 0.259477
ALPPL2 alkaline phosphatase, placental-like 2 0.250663
ALPP alkaline phosphatase, placental 0.250311
ALPL alkaline phosphatase, liver/bone/kidney 0.249608
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.24715
KRT18 keratin 18, type I 0.243995
MUC1 mucin 1, cell surface associated 0.241196
VIMP VCP-interacting membrane selenoprotein 0.239799
BPI bactericidal/permeability-increasing protein 0.23945
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.238054
AJAP1 adherens junctions associated protein 1 0.235268
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.232489
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.232142
IGHA1 immunoglobulin heavy constant alpha 1 0.231795
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.226607
KRT84 keratin 84, type II 0.225917
IL2RA interleukin 2 receptor, alpha 0.224884
TNF tumor necrosis factor 0.223509
SFTPB surfactant protein B 0.222136
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.220424
DYNLL1 dynein, light chain, LC8-type 1 0.21974
NCAM1 neural cell adhesion molecule 1 0.217012
CD24 CD24 molecule 0.216672
TG thyroglobulin 0.209248
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.208579
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 0.205916
AICDA activation-induced cytidine deaminase 0.202618
WRAP73 WD repeat containing, antisense to TP73 0.20229
ELN elastin 0.201308
PTPRC protein tyrosine phosphatase, receptor type, C 0.200006
TOP2B topoisomerase (DNA) II beta 180kDa 0.198709
DCK deoxycytidine kinase 0.198064
BLNK B-cell linker 0.19582
MMP26 matrix metallopeptidase 26 0.194232
CTSE cathepsin E 0.192971
NOTCH2 notch 2 0.191408
ACPP acid phosphatase, prostate 0.191097
CTSG cathepsin G 0.191097
NOTCH2NL notch 2 N-terminal like 0.189244
PI3 peptidase inhibitor 3, skin-derived 0.188938
BCR breakpoint cluster region 0.186811
MANBA mannosidase, beta A, lysosomal 0.181222
ARID1B AT rich interactive domain 1B (SWI1-like) 0.180937
DGUOK deoxyguanosine kinase 0.175679
B3GAT1 beta-1,3-glucuronyltransferase 1 0.175411
IRF4 interferon regulatory factor 4 0.174354
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 0.173832
GSTA1 glutathione S-transferase alpha 1 0.172799
CXCL12 chemokine (C-X-C motif) ligand 12 0.170054
HDAC5 histone deacetylase 5 0.169091
HAS3 hyaluronan synthase 3 0.168854
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 0.165435
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.143296
GZMM granzyme M (lymphocyte met-ase 1) 0.138324
FICD FIC domain containing 0.137177
CD2 CD2 molecule 0.136306
VIL1 villin 1 0.135901
ADAM17 ADAM metallopeptidase domain 17 0.132351
NAAA N-acylethanolamine acid amidase 0.132037
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.131105
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.130995
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.130674
TFEB transcription factor EB 0.130538
TRIM21 tripartite motif containing 21 0.130422
JAG1 jagged 1 0.130104
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.129673
THEM4 thioesterase superfamily member 4 0.129526
CXCL13 chemokine (C-X-C motif) ligand 13 0.129226
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.128806
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.128783
ATP7B ATPase, Cu++ transporting, beta polypeptide 0.128254
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.12809
GSTP1 glutathione S-transferase pi 1 0.128042
HSPG2 heparan sulfate proteoglycan 2 0.128018
IGHV4-34 immunoglobulin heavy variable 4-34 0.127969
SH2D1A SH2 domain containing 1A 0.127872
AZU1 azurocidin 1 0.127504
ARHGAP1 Rho GTPase activating protein 1 0.127479
STYK1 serine/threonine/tyrosine kinase 1 0.127429
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.127178
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.126919
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 0.126919
AGO2 argonaute RISC catalytic component 2 0.126868
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.126764
BST2 bone marrow stromal cell antigen 2 0.126711
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.126604
KMT2B lysine (K)-specific methyltransferase 2B 0.12639
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.1262
IL6R interleukin 6 receptor 0.125924
AVP arginine vasopressin 0.125728
PRDM2 PR domain containing 2, with ZNF domain 0.1255
CD9 CD9 molecule 0.125471
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.125443
PNP purine nucleoside phosphorylase 0.125386
GSTM3 glutathione S-transferase mu 3 (brain) 0.124857
TOB1 transducer of ERBB2, 1 0.124737
PSG9 pregnancy specific beta-1-glycoprotein 9 0.124646
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.124493
NRCAM neuronal cell adhesion molecule 0.124217
IRAK4 interleukin-1 receptor-associated kinase 4 0.123517
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 0.123321
MAGEC1 melanoma antigen family C1 0.123223
APOA2 apolipoprotein A-II 0.123091
ATM ATM serine/threonine kinase 0.123057
RARS arginyl-tRNA synthetase 0.122517
CCL17 chemokine (C-C motif) ligand 17 0.122517
FGF3 fibroblast growth factor 3 0.122273
LBP lipopolysaccharide binding protein 0.122238
FMOD fibromodulin 0.121491
GADD45B growth arrest and DNA-damage-inducible, beta 0.121455
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.121419
EPO erythropoietin 0.120753
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 0.120447
CTSS cathepsin S 0.119707
SIRT5 sirtuin 5 0.119627
EPHB2 EPH receptor B2 0.119587
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.119268
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.118272