plasma membrane raft Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A membrane raft that is part of the plasma membrane. (Gene Ontology, GO_0044853)
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Genes

263 proteins co-occuring with the plasma membrane raft cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CAV1 caveolin 1, caveolae protein, 22kDa 4.32458
CAV3 caveolin 3 2.90856
CAV2 caveolin 2 2.44775
PTRF polymerase I and transcript release factor 2.2164
NOS3 nitric oxide synthase 3 (endothelial cell) 2.10711
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.50735
FLOT2 flotillin 2 1.49549
FLOT1 flotillin 1 1.47287
SCARB1 scavenger receptor class B, member 1 1.23766
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.13983
ALB albumin 1.10868
FYN FYN proto-oncogene, Src family tyrosine kinase 1.06448
INSR insulin receptor 1.04431
PLVAP plasmalemma vesicle associated protein 1.02032
EPS15 epidermal growth factor receptor pathway substrate 15 0.971297
KNG1 kininogen 1 0.949236
INS insulin 0.928422
DNM2 dynamin 2 0.922322
ADCY2 adenylate cyclase 2 (brain) 0.901353
EGFR epidermal growth factor receptor 0.894406
PLAA phospholipase A2-activating protein 0.884244
TF transferrin 0.88286
SDPR serum deprivation response 0.881016
HRAS Harvey rat sarcoma viral oncogene homolog 0.856635
LYN LYN proto-oncogene, Src family tyrosine kinase 0.85342
FTL ferritin, light polypeptide 0.841023
FTH1 ferritin, heavy polypeptide 1 0.838728
PRKCDBP protein kinase C, delta binding protein 0.819911
CD36 CD36 molecule (thrombospondin receptor) 0.81257
ANXA2 annexin A2 0.804313
PRNP prion protein 0.767715
CTSA cathepsin A 0.752716
ADCY6 adenylate cyclase 6 0.748641
PLD2 phospholipase D2 0.745025
SCP2 sterol carrier protein 2 0.742769
SCARB2 scavenger receptor class B, member 2 0.739163
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.731973
OCLN occludin 0.726152
EEA1 early endosome antigen 1 0.71768
EHD2 EH-domain containing 2 0.708366
TFRC transferrin receptor 0.693832
VEGFA vascular endothelial growth factor A 0.670292
ARF6 ADP-ribosylation factor 6 0.65905
CSK c-src tyrosine kinase 0.658619
DNAH8 dynein, axonemal, heavy chain 8 0.64915
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.646574
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.645716
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.626057
MURC muscle-related coiled-coil protein 0.612048
SRI sorcin 0.610778
ZHX2 zinc fingers and homeoboxes 2 0.608241
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.606128
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.605706
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.605706
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.600644
JAKMIP3 Janus kinase and microtubule interacting protein 3 0.596014
ADTRP androgen-dependent TFPI-regulating protein 0.595593
GSTA3 glutathione S-transferase alpha 3 0.590973
GSTA2 glutathione S-transferase alpha 2 0.588875
GSTA4 glutathione S-transferase alpha 4 0.588875
GSTA1 glutathione S-transferase alpha 1 0.586361
ESR1 estrogen receptor 1 0.584268
ARRB1 arrestin, beta 1 0.580922
IRS1 insulin receptor substrate 1 0.556387
KDR kinase insert domain receptor 0.556387
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.555973
LCK LCK proto-oncogene, Src family tyrosine kinase 0.542764
CD9 CD9 molecule 0.538649
LDLR low density lipoprotein receptor 0.534951
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.52716
CD81 CD81 molecule 0.525931
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.525113
PDIA3 protein disulfide isomerase family A, member 3 0.521023
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.504724
MYOF myoferlin 0.500664
CLDN5 claudin 5 0.497015
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.49661
MAL mal, T-cell differentiation protein 0.490944
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.483676
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.480855
STOM stomatin 0.48005
UGCG UDP-glucose ceramide glucosyltransferase 0.476429
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.475625
F3 coagulation factor III (thromboplastin, tissue factor) 0.47442
DYSF dysferlin 0.470807
FOLR1 folate receptor 1 (adult) 0.470807
BST1 bone marrow stromal cell antigen 1 0.4672
FAM21C family with sequence similarity 21, member C 0.460401
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.45641
ADRB2 adrenoceptor beta 2, surface 0.452825
ZDHHC19 zinc finger, DHHC-type containing 19 0.451233
APOE apolipoprotein E 0.45004
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.448451
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.438146
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.430647
ARRB2 arrestin, beta 2 0.429859
RHOQ ras homolog family member Q 0.425138
TSPAN17 tetraspanin 17 0.425138
DMD dystrophin 0.421212
FN1 fibronectin 1 0.417685
PROM1 prominin 1 0.415728
PPID peptidylprolyl isomerase D 0.413773
PROM2 prominin 2 0.411039
EDN1 endothelin 1 0.409869
CDC42 cell division cycle 42 0.408699
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.407919
GRB2 growth factor receptor-bound protein 2 0.403248
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.399751
ALPP alkaline phosphatase, placental 0.399363
ALPPL2 alkaline phosphatase, placental-like 2 0.399363
ALPL alkaline phosphatase, liver/bone/kidney 0.398975
CCL2 chemokine (C-C motif) ligand 2 0.392775
ANPEP alanyl (membrane) aminopeptidase 0.391615
TLR4 toll-like receptor 4 0.390455
CD34 CD34 molecule 0.388909
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.38428
TSPAN14 tetraspanin 14 0.382739
PLCG1 phospholipase C, gamma 1 0.380429
FOLR2 folate receptor 2 (fetal) 0.377738
UPK3A uroplakin 3A 0.371982
DNM1 dynamin 1 0.365477
EDNRA endothelin receptor type A 0.364713
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.363185
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.363185
ANXA6 annexin A6 0.361659
STX4 syntaxin 4 0.358609
LAMP1 lysosomal-associated membrane protein 1 0.355944
THY1 Thy-1 cell surface antigen 0.353662
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 0.353282
DHCR24 24-dehydrocholesterol reductase 0.352901
IARS isoleucyl-tRNA synthetase 0.351762
APOA1 apolipoprotein A-I 0.347587
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.347208
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 0.345314
IGF1R insulin-like growth factor 1 receptor 0.344178
GPC1 glypican 1 0.340395
TGFB1 transforming growth factor, beta 1 0.338128
AQP1 aquaporin 1 (Colton blood group) 0.333979
NEU3 sialidase 3 (membrane sialidase) 0.333602
ITSN1 intersectin 1 (SH3 domain protein) 0.332472
FGF2 fibroblast growth factor 2 (basic) 0.332095
TSPAN10 tetraspanin 10 0.329461
CD44 CD44 molecule (Indian blood group) 0.329461
ARHGAP26 Rho GTPase activating protein 26 0.327581
PKN1 protein kinase N1 0.321201
STRN striatin, calmodulin binding protein 0.318205
ADCY8 adenylate cyclase 8 (brain) 0.317456
ACE angiotensin I converting enzyme 0.317082
ACTN1 actinin, alpha 1 0.317082
TSPAN15 tetraspanin 15 0.315586
PLIN1 perilipin 1 0.313344
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.311105
IGF1 insulin-like growth factor 1 (somatomedin C) 0.310732
PLLP plasmolipin 0.307749
PLAU plasminogen activator, urokinase 0.306632
CLDN7 claudin 7 0.306632
ICAM1 intercellular adhesion molecule 1 0.305888
TGFBR1 transforming growth factor, beta receptor 1 0.305143
AGTR1 angiotensin II receptor, type 1 0.303655
TP53 tumor protein p53 0.29623
CD109 CD109 molecule 0.294748
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.292527
CD4 CD4 molecule 0.292157
GAPT GRB2-binding adaptor protein, transmembrane 0.290308
TMC6 transmembrane channel-like 6 0.286245
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.285138
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.284032
ZDHHC21 zinc finger, DHHC-type containing 21 0.283663
NPC1 Niemann-Pick disease, type C1 0.281085
TSPAN33 tetraspanin 33 0.278509
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.277774
MAPK14 mitogen-activated protein kinase 14 0.277038
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.276304
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.275569
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 0.274835
UPK1B uroplakin 1B 0.272267
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.270434
KSR1 kinase suppressor of ras 1 0.269701
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 0.265311
MAPK3 mitogen-activated protein kinase 3 0.264215
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.26312
ESR2 estrogen receptor 2 (ER beta) 0.262025
RBP5 retinol binding protein 5, cellular 0.261296
HBEGF heparin-binding EGF-like growth factor 0.259837
BEND3 BEN domain containing 3 0.258381
PLD1 phospholipase D1, phosphatidylcholine-specific 0.257652
SI sucrase-isomaltase (alpha-glucosidase) 0.256925
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.255107
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.253653
TSPAN8 tetraspanin 8 0.251476
FAAH fatty acid amide hydrolase 0.249302
NT5E 5'-nucleotidase, ecto (CD73) 0.246046
LAT2 linker for activation of T cells family, member 2 0.242076
HMOX1 heme oxygenase 1 0.241356
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.239557
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.239197
LAT linker for activation of T cells 0.239197
SFXN1 sideroflexin 1 0.239197
PPAP2B phosphatidic acid phosphatase type 2B 0.237401
TJP1 tight junction protein 1 0.237401
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.237042
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 0.237042
MMP2 matrix metallopeptidase 2 0.235966
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.233101
CCND1 cyclin D1 0.232386
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.229532
CDH13 cadherin 13 0.228108
ACTN4 actinin, alpha 4 0.228108
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.224204
BDKRB2 bradykinin receptor B2 0.22385
NPPA natriuretic peptide A 0.222436
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.221378
SESTD1 SEC14 and spectrin domains 1 0.220321
F10 coagulation factor X 0.218563
PLEK pleckstrin 0.217861
NGF nerve growth factor (beta polypeptide) 0.215761
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.215063
SNAP23 synaptosomal-associated protein, 23kDa 0.215063
VCAM1 vascular cell adhesion molecule 1 0.213322
CD40 CD40 molecule, TNF receptor superfamily member 5 0.210894
MFF mitochondrial fission factor 0.210203
ERLIN2 ER lipid raft associated 2 0.208481
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 0.208137
SMAD2 SMAD family member 2 0.207794
EDNRB endothelin receptor type B 0.207108
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.206766
CNR1 cannabinoid receptor 1 (brain) 0.206082
STX6 syntaxin 6 0.205399
BASP1 brain abundant, membrane attached signal protein 1 0.204378
MMP9 matrix metallopeptidase 9 0.202346
LYPLA1 lysophospholipase I 0.202009
GLTP glycolipid transfer protein 0.199993
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.199993
CD59 CD59 molecule, complement regulatory protein 0.199993
PLCD1 phospholipase C, delta 1 0.198325
HCK HCK proto-oncogene, Src family tyrosine kinase 0.196669
GPM6B glycoprotein M6B 0.192746
CCR2 chemokine (C-C motif) receptor 2 0.189857
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 0.184853
AGER advanced glycosylation end product-specific receptor 0.184241
BMP2 bone morphogenetic protein 2 0.181524
EPHB1 EPH receptor B1 0.18093
CTSB cathepsin B 0.179752
PROCR protein C receptor, endothelial 0.177724
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.176024
KRAS Kirsten rat sarcoma viral oncogene homolog 0.175466
CDH5 cadherin 5, type 2 (vascular endothelium) 0.174911
NGFR nerve growth factor receptor 0.174635
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.174361
UPK1A uroplakin 1A 0.173543
ERBB2 erb-b2 receptor tyrosine kinase 2 0.168847
IL1B interleukin 1, beta 0.168101
VCL vinculin 0.168101
THBD thrombomodulin 0.166884
TFPI2 tissue factor pathway inhibitor 2 0.166643
AMPH amphiphysin 0.165697
SCN4A sodium channel, voltage gated, type IV alpha subunit 0.162546
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.161905
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.161693
UBXN6 UBX domain protein 6 0.160053
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.158129
EZR ezrin 0.156863
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.156513