plasma lipoprotein particle Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph. (Gene Ontology, GO_0034358)
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Genes

718 proteins co-occuring with the plasma lipoprotein particle cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
APOB apolipoprotein B 5.68589
LPA lipoprotein, Lp(a) 4.04358
APOE apolipoprotein E 4.00806
APOA1 apolipoprotein A-I 3.96255
COG2 component of oligomeric golgi complex 2 3.75738
LPL lipoprotein lipase 3.51219
CRP C-reactive protein, pentraxin-related 3.45414
INS insulin 3.31303
LDLR low density lipoprotein receptor 3.11339
CETP cholesteryl ester transfer protein, plasma 3.09806
APOA2 apolipoprotein A-II 2.88302
LCAT lecithin-cholesterol acyltransferase 2.85847
PON1 paraoxonase 1 2.79563
APOC3 apolipoprotein C-III 2.75509
SCARB1 scavenger receptor class B, member 1 2.73059
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 2.56713
ALB albumin 2.50906
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 2.50381
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 2.3968
SCARB2 scavenger receptor class B, member 2 2.31528
CD36 CD36 molecule (thrombospondin receptor) 2.31132
PCSK9 proprotein convertase subtilisin/kexin type 9 2.30499
MTTP microsomal triglyceride transfer protein 2.17125
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.10274
LEP leptin 2.07579
PLTP phospholipid transfer protein 2.03361
LIPC lipase, hepatic 2.017
ACE angiotensin I converting enzyme 1.91604
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.8266
VCAM1 vascular cell adhesion molecule 1 1.82118
MYDGF myeloid-derived growth factor 1.81781
SHBG sex hormone-binding globulin 1.80975
SOD2 superoxide dismutase 2, mitochondrial 1.77796
APOC2 apolipoprotein C-II 1.76045
ICAM1 intercellular adhesion molecule 1 1.7187
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.71621
APOA5 apolipoprotein A-V 1.71559
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.70939
IL6 interleukin 6 1.69891
CCL2 chemokine (C-C motif) ligand 2 1.69891
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 1.68543
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.62945
NOS3 nitric oxide synthase 3 (endothelial cell) 1.62118
SELE selectin E 1.61764
PPARG peroxisome proliferator-activated receptor gamma 1.61764
TGM4 transglutaminase 4 1.61764
CHD1L chromodomain helicase DNA binding protein 1-like 1.61529
VWF von Willebrand factor 1.60301
PLG plasminogen 1.60127
GPX1 glutathione peroxidase 1 1.57073
GPX5 glutathione peroxidase 5 1.56788
GPX4 glutathione peroxidase 4 1.5656
VLDLR very low density lipoprotein receptor 1.55821
PLA2G1B phospholipase A2, group IB (pancreas) 1.55594
APOH apolipoprotein H (beta-2-glycoprotein I) 1.53952
TNF tumor necrosis factor 1.53952
LIPG lipase, endothelial 1.53726
USF1 upstream transcription factor 1 1.51186
PON2 paraoxonase 2 1.50566
SREBF2 sterol regulatory element binding transcription factor 2 1.50227
APOA4 apolipoprotein A-IV 1.48023
RETN resistin 1.47853
APOC1 apolipoprotein C-I 1.46608
MPO myeloperoxidase 1.46552
GGT1 gamma-glutamyltransferase 1 1.42092
HBA2 hemoglobin, alpha 2 1.40802
SCARF1 scavenger receptor class F, member 1 1.40019
PPARA peroxisome proliferator-activated receptor alpha 1.3974
HBA1 hemoglobin, alpha 1 1.39573
F7 coagulation factor VII (serum prothrombin conversion accelerator) 1.39294
CAT catalase 1.39183
PON3 paraoxonase 3 1.38461
SREBF1 sterol regulatory element binding transcription factor 1 1.38183
PLAT plasminogen activator, tissue 1.35375
IGF1 insulin-like growth factor 1 (somatomedin C) 1.30336
CEL carboxyl ester lipase 1.29424
TF transferrin 1.2825
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 1.2777
CSN1S1 casein alpha s1 1.27717
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 1.27399
ALPL alkaline phosphatase, liver/bone/kidney 1.26392
ALPPL2 alkaline phosphatase, placental-like 2 1.26286
ALPP alkaline phosphatase, placental 1.26181
COG1 component of oligomeric golgi complex 1 1.2518
SOAT1 sterol O-acyltransferase 1 1.22932
ANGPTL3 angiopoietin-like 3 1.22828
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.22672
FASN fatty acid synthase 1.22464
NPC1L1 NPC1-like 1 1.2236
APOM apolipoprotein M 1.22101
F3 coagulation factor III (thromboplastin, tissue factor) 1.22101
SPINK5 serine peptidase inhibitor, Kazal type 5 1.18851
APOF apolipoprotein F 1.18235
PNLIP pancreatic lipase 1.1803
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.16389
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.15825
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 1.15672
SAA1 serum amyloid A1 1.15057
PLGLB1 plasminogen-like B1 1.15006
NPC1 Niemann-Pick disease, type C1 1.14853
APOD apolipoprotein D 1.12654
RBP4 retinol binding protein 4, plasma 1.12296
DLL1 delta-like 1 (Drosophila) 1.12143
NAMPT nicotinamide phosphoribosyltransferase 1.12092
IL1B interleukin 1, beta 1.09391
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 1.0934
FABP2 fatty acid binding protein 2, intestinal 1.09289
MMP9 matrix metallopeptidase 9 1.08222
KDR kinase insert domain receptor 1.07765
GCG glucagon 1.07157
CXCL16 chemokine (C-X-C motif) ligand 16 1.0569
F2 coagulation factor II (thrombin) 1.04331
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.02082
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.01387
FTH1 ferritin, heavy polypeptide 1 1.01189
HMGA2 high mobility group AT-hook 2 1.00843
HPR haptoglobin-related protein 1.003
CP ceruloplasmin (ferroxidase) 1.00103
F8 coagulation factor VIII, procoagulant component 1.00005
PCDH8 protocadherin 8 0.999068
PTH parathyroid hormone 0.998086
DGAT1 diacylglycerol O-acyltransferase 1 0.997595
DGAT2 diacylglycerol O-acyltransferase 2 0.994162
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.993183
FTL ferritin, light polypeptide 0.991225
HP haptoglobin 0.984393
POMC proopiomelanocortin 0.978074
ELANE elastase, neutrophil expressed 0.977104
HCAR2 hydroxycarboxylic acid receptor 2 0.972747
NR1H3 nuclear receptor subfamily 1, group H, member 3 0.966474
CDH5 cadherin 5, type 2 (vascular endothelium) 0.962627
EDN1 endothelin 1 0.954961
ETV3 ets variant 3 0.954005
CD4 CD4 molecule 0.952573
CD40LG CD40 ligand 0.949236
PSRC1 proline/serine-rich coiled-coil 1 0.938322
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.93785
PROM1 prominin 1 0.936905
MYLIP myosin regulatory light chain interacting protein 0.934544
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.933129
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.925135
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.919514
LIPE lipase, hormone-sensitive 0.913443
LRP2 low density lipoprotein receptor-related protein 2 0.911113
PLA2G10 phospholipase A2, group X 0.910647
REN renin 0.910182
SDC2 syndecan 2 0.908785
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.90739
GHRL ghrelin/obestatin prepropeptide 0.905996
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.905531
SORT1 sortilin 1 0.897646
SOAT2 sterol O-acyltransferase 2 0.893018
KNG1 kininogen 1 0.887474
FN1 fibronectin 1 0.881938
TLR4 toll-like receptor 4 0.880555
CST3 cystatin C 0.879633
CD34 CD34 molecule 0.872266
GGT2 gamma-glutamyltransferase 2 0.872266
ANGPTL4 angiopoietin-like 4 0.870426
LRP5 low density lipoprotein receptor-related protein 5 0.863988
CXCL8 chemokine (C-X-C motif) ligand 8 0.858473
GSR glutathione reductase 0.85388
KIAA0101 KIAA0101 0.850206
CES1 carboxylesterase 1 0.846991
FBXL20 F-box and leucine-rich repeat protein 20 0.841023
SAR1B secretion associated, Ras related GTPase 1B 0.836892
FADS1 fatty acid desaturase 1 0.835056
TTR transthyretin 0.830925
GIP gastric inhibitory polypeptide 0.823582
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.822664
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.819911
THBD thrombomodulin 0.818534
LDLRAP1 low density lipoprotein receptor adaptor protein 1 0.816699
CD68 CD68 molecule 0.813028
TGFA transforming growth factor, alpha 0.809817
APOL1 apolipoprotein L, 1 0.803855
TTPA tocopherol (alpha) transfer protein 0.802021
ESR1 estrogen receptor 1 0.796979
MSR1 macrophage scavenger receptor 1 0.793313
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 0.792396
SLCO1B1 solute carrier organic anion transporter family, member 1B1 0.786444
LEPR leptin receptor 0.775014
BGN biglycan 0.774101
TGFB1 transforming growth factor, beta 1 0.773645
FABP4 fatty acid binding protein 4, adipocyte 0.76726
VEGFA vascular endothelial growth factor A 0.76726
AHSG alpha-2-HS-glycoprotein 0.761342
MMP2 matrix metallopeptidase 2 0.757253
PCSK7 proprotein convertase subtilisin/kexin type 7 0.745929
LTF lactotransferrin 0.745929
PEMT phosphatidylethanolamine N-methyltransferase 0.737363
SAA2 serum amyloid A2 0.735565
FADS2 fatty acid desaturase 2 0.735115
IRF6 interferon regulatory factor 6 0.734666
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.720797
CD79A CD79a molecule, immunoglobulin-associated alpha 0.71946
IFNL3 interferon, lambda 3 0.718125
PNPLA3 patatin-like phospholipase domain containing 3 0.716791
FLT1 fms-related tyrosine kinase 1 0.713682
HMOX1 heme oxygenase 1 0.713238
LRP6 low density lipoprotein receptor-related protein 6 0.712795
TXNL4B thioredoxin-like 4B 0.708808
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.705714
PROS1 protein S (alpha) 0.696465
PTAFR platelet-activating factor receptor 0.694709
JUN jun proto-oncogene 0.693832
TRIB1 tribbles pseudokinase 1 0.691202
LRP1B low density lipoprotein receptor-related protein 1B 0.689888
PLIN2 perilipin 2 0.689013
IL10 interleukin 10 0.687264
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.686827
BGLAP bone gamma-carboxyglutamate (gla) protein 0.678108
FGF21 fibroblast growth factor 21 0.672894
PGF placental growth factor 0.67246
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.67246
APOC4 apolipoprotein C-IV 0.670725
INSR insulin receptor 0.669425
MANF mesencephalic astrocyte-derived neurotrophic factor 0.668126
APOBR apolipoprotein B receptor 0.66726
KIF6 kinesin family member 6 0.664232
CYBA cytochrome b-245, alpha polypeptide 0.663368
LOX lysyl oxidase 0.660345
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.644858
ESAM endothelial cell adhesion molecule 0.638434
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.63715
PF4 platelet factor 4 0.635013
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.635013
CXCR6 chemokine (C-X-C motif) receptor 6 0.631598
SOD3 superoxide dismutase 3, extracellular 0.631598
CAV1 caveolin 1, caveolae protein, 22kDa 0.630745
MLXIPL MLX interacting protein-like 0.630318
CADM1 cell adhesion molecule 1 0.617982
CCR2 chemokine (C-C motif) receptor 2 0.616709
HMGA1 high mobility group AT-hook 1 0.612471
GLP1R glucagon-like peptide 1 receptor 0.612048
BCHE butyrylcholinesterase 0.610355
NAT10 N-acetyltransferase 10 (GCN5-related) 0.608241
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.604862
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.601487
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.592232
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.590973
IL18 interleukin 18 0.590553
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.585523
CXCL14 chemokine (C-X-C motif) ligand 14 0.582594
FGF2 fibroblast growth factor 2 (basic) 0.577164
ADRB3 adrenoceptor beta 3 0.575495
LBP lipopolysaccharide binding protein 0.570913
COASY CoA synthase 0.567169
UBAP1 ubiquitin associated protein 1 0.566338
ACLY ATP citrate lyase 0.563017
ADIPOQ adiponectin, C1Q and collagen domain containing 0.562187
PPP1R3B protein phosphatase 1, regulatory subunit 3B 0.560528
TLR2 toll-like receptor 2 0.5568
MGAM maltase-glucoamylase 0.555559
FTO fat mass and obesity associated 0.554318
PER2 period circadian clock 2 0.550186
CILP2 cartilage intermediate layer protein 2 0.548947
G6PD glucose-6-phosphate dehydrogenase 0.546472
MLX MLX, MAX dimerization protein 0.541117
ANXA5 annexin A5 0.539472
CMA1 chymase 1, mast cell 0.537827
TSPO translocator protein (18kDa) 0.534951
ACAT1 acetyl-CoA acetyltransferase 1 0.531258
CD40 CD40 molecule, TNF receptor superfamily member 5 0.527979
CD44 CD44 molecule (Indian blood group) 0.52716
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.525522
AGER advanced glycosylation end product-specific receptor 0.525522
PCYOX1 prenylcysteine oxidase 1 0.524294
PER1 period circadian clock 1 0.524294
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.523067
CBY3 chibby homolog 3 (Drosophila) 0.52225
IRS1 insulin receptor substrate 1 0.519389
LIPA lipase A, lysosomal acid, cholesterol esterase 0.518573
UTS2 urotensin 2 0.517756
STAB1 stabilin 1 0.517756
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.517348
PRL prolactin 0.51694
ACSS2 acyl-CoA synthetase short-chain family member 2 0.51694
CIDEB cell death-inducing DFFA-like effector b 0.516532
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 0.515716
PYY peptide YY 0.514085
STARD8 StAR-related lipid transfer (START) domain containing 8 0.510011
DPP4 dipeptidyl-peptidase 4 0.506757
IGFBP3 insulin-like growth factor binding protein 3 0.499042
IL1A interleukin 1, alpha 0.49742
SQLE squalene epoxidase 0.490944
NPC2 Niemann-Pick disease, type C2 0.490539
C3 complement component 3 0.485289
FBL fibrillarin 0.484079
DUOX2 dual oxidase 2 0.483676
CTSC cathepsin C 0.479245
MMP1 matrix metallopeptidase 1 0.478038
PLAU plasminogen activator, urokinase 0.477233
FADS3 fatty acid desaturase 3 0.476429
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.472813
GSTA1 glutathione S-transferase alpha 1 0.472011
RXFP1 relaxin/insulin-like family peptide receptor 1 0.468001
GSTA3 glutathione S-transferase alpha 3 0.4676
CLU clusterin 0.4672
DUOX1 dual oxidase 1 0.4672
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.466799
GSTA2 glutathione S-transferase alpha 2 0.465998
GSTA4 glutathione S-transferase alpha 4 0.465998
SCAP SREBF chaperone 0.465598
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.461199
NOX4 NADPH oxidase 4 0.4608
FLAD1 flavin adenine dinucleotide synthetase 1 0.453621
VCAN versican 0.453621
FGF1 fibroblast growth factor 1 (acidic) 0.452427
MCAM melanoma cell adhesion molecule 0.452029
MGP matrix Gla protein 0.449643
F12 coagulation factor XII (Hageman factor) 0.449643
ELOVL2 ELOVL fatty acid elongase 2 0.446069
PBX4 pre-B-cell leukemia homeobox 4 0.445672
CABIN1 calcineurin binding protein 1 0.445275
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 0.444878
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.444482
PPARD peroxisome proliferator-activated receptor delta 0.44052
VAT1 vesicle amine transport 1 0.438542
TIMP1 TIMP metallopeptidase inhibitor 1 0.437751
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.433407
MAPK3 mitogen-activated protein kinase 3 0.433012
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.431829
CTSD cathepsin D 0.431435
PLA2G2D phospholipase A2, group IID 0.430647
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.429465
KLK3 kallikrein-related peptidase 3 0.429072
IGLV3-10 immunoglobulin lambda variable 3-10 0.427104
IGLV3-9 immunoglobulin lambda variable 3-9 (gene/pseudogene) 0.425924
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 0.422389
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 0.422389
THADA thyroid adenoma associated 0.41612
TTC39B tetratricopeptide repeat domain 39B 0.414164
ACPP acid phosphatase, prostate 0.412601
PDGFB platelet-derived growth factor beta polypeptide 0.410649
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.409089
SIRT1 sirtuin 1 0.408309
PLA2G12B phospholipase A2, group XIIB 0.406361
CDH13 cadherin 13 0.403248
AADAC arylacetamide deacetylase 0.402859
TFRC transferrin receptor 0.402081
ALLC allantoicase 0.399751
RXFP2 relaxin/insulin-like family peptide receptor 2 0.398199
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.397423
MVK mevalonate kinase 0.395098
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.393936
IGLV5-48 immunoglobulin lambda variable 5-48 (non-functional) 0.393936
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.393549
DCN decorin 0.392388
CXCL12 chemokine (C-X-C motif) ligand 12 0.392001
PNPLA2 patatin-like phospholipase domain containing 2 0.386208
TGM5 transglutaminase 5 0.386208
IGLV1-47 immunoglobulin lambda variable 1-47 0.381199
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.378891
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.377738
CLPS colipase, pancreatic 0.377354
F5 coagulation factor V (proaccelerin, labile factor) 0.374283
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.369684
TTC34 tetratricopeptide repeat domain 34 0.369301
SUGP1 SURP and G patch domain containing 1 0.367771
F9 coagulation factor IX 0.367006
ITLN1 intelectin 1 (galactofuranose binding) 0.363949
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.362422
ZPR1 ZPR1 zinc finger 0.361277
ZNF664 zinc finger protein 664 0.360896
AMY2A amylase, alpha 2A (pancreatic) 0.360515
LPIN1 lipin 1 0.360133
LPIN2 lipin 2 0.359752
FGD1 FYVE, RhoGEF and PH domain containing 1 0.359371
ADRB2 adrenoceptor beta 2, surface 0.355944
SRY sex determining region Y 0.354802
HDLBP high density lipoprotein binding protein 0.353282
SCP2 sterol carrier protein 2 0.353282
ALOX15 arachidonate 15-lipoxygenase 0.352901
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.351002
STAR steroidogenic acute regulatory protein 0.350622
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.350622
CYGB cytoglobin 0.346829
MAPK8 mitogen-activated protein kinase 8 0.338884
HPX hemopexin 0.338128
STAB2 stabilin 2 0.336996
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.335864
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.335487
PLIN1 perilipin 1 0.33511
C6ORF25 chromosome 6 open reading frame 25 0.333602
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 0.332095
STX8 syntaxin 8 0.331719
FOXO1 forkhead box O1 0.330213
NUTM1 NUT midline carcinoma, family member 1 0.328332
LCA10 lung carcinoma-associated 10 0.328332
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.327581
FGF19 fibroblast growth factor 19 0.327581
SOST sclerostin 0.326829
GLB1 galactosidase, beta 1 0.326829
PLA2G2E phospholipase A2, group IIE 0.326078
ZDHHC23 zinc finger, DHHC-type containing 23 0.323075
CES3 carboxylesterase 3 0.32195
GPR135 G protein-coupled receptor 135 0.319328
GPR85 G protein-coupled receptor 85 0.318579
CFD complement factor D (adipsin) 0.317456
TNNT2 troponin T type 2 (cardiac) 0.317082
CD86 CD86 molecule 0.317082
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.317082
IL2 interleukin 2 0.314091
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.314091
ACACA acetyl-CoA carboxylase alpha 0.307377
BAX BCL2-associated X protein 0.306632
ALOX5 arachidonate 5-lipoxygenase 0.306632
CPT1A carnitine palmitoyltransferase 1A (liver) 0.305888
CPB2 carboxypeptidase B2 (plasma) 0.305143
CD163 CD163 molecule 0.303283
PDZK1 PDZ domain containing 1 0.300311
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 0.29994
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.299197
INSIG2 insulin induced gene 2 0.29623
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 0.29623
RELN reelin 0.29586
SDC1 syndecan 1 0.295489
PRODH proline dehydrogenase (oxidase) 1 0.292157
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.291787
IRS2 insulin receptor substrate 2 0.291417
OSBP oxysterol binding protein 0.291047
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 0.288091
CD81 CD81 molecule 0.285507
LSR lipolysis stimulated lipoprotein receptor 0.284032
FOXP3 forkhead box P3 0.282558
LTB4R leukotriene B4 receptor 0.280716
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 0.279612
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 0.279245
GPANK1 G patch domain and ankyrin repeats 1 0.278141
ICAM2 intercellular adhesion molecule 2 0.277406
DHCR7 7-dehydrocholesterol reductase 0.277406
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.277038
INSL3 insulin-like 3 (Leydig cell) 0.276671
ELOVL6 ELOVL fatty acid elongase 6 0.276304
SAA4 serum amyloid A4, constitutive 0.275569
HSPA4 heat shock 70kDa protein 4 0.274468
GCK glucokinase (hexokinase 4) 0.2708
TPO thyroid peroxidase 0.268969
HBEGF heparin-binding EGF-like growth factor 0.268237
INSIG1 insulin induced gene 1 0.267871
ESR2 estrogen receptor 2 (ER beta) 0.267871
GPX3 glutathione peroxidase 3 0.267139
CBY1 chibby homolog 1 (Drosophila) 0.266408
FBLL1 fibrillarin-like 1 0.262025
TIMP2 TIMP metallopeptidase inhibitor 2 0.259473
APOO apolipoprotein O 0.258745
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.258381
CBS cystathionine-beta-synthase 0.257289
C5AR2 complement component 5a receptor 2 0.256561
PRSS30P protease, serine, 30, pseudogene 0.255834
IL4 interleukin 4 0.253653
HNF1A HNF1 homeobox A 0.252927
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.251114
THBS1 thrombospondin 1 0.248578
EGR1 early growth response 1 0.248216
BTN2A1 butyrophilin, subfamily 2, member A1 0.248216
SST somatostatin 0.248216
NOVA2 neuro-oncological ventral antigen 2 0.247854
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.246769
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.243879
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 0.242797
SRR serine racemase 0.241356
CNR1 cannabinoid receptor 1 (brain) 0.240276
MMP3 matrix metallopeptidase 3 0.240276
IGLV9-49 immunoglobulin lambda variable 9-49 0.239557
MAPK14 mitogen-activated protein kinase 14 0.234891
ASRGL1 asparaginase like 1 0.232744
SRFBP1 serum response factor binding protein 1 0.231315
FBLIM1 filamin binding LIM protein 1 0.231315
BPI bactericidal/permeability-increasing protein 0.230958
ADIPOR1 adiponectin receptor 1 0.230245
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.229532
CFH complement factor H 0.229176
FOS FBJ murine osteosarcoma viral oncogene homolog 0.228819
LYPLAL1 lysophospholipase-like 1 0.227752
EDNRA endothelin receptor type A 0.227397
NOS2 nitric oxide synthase 2, inducible 0.225267
C5AR1 complement component 5a receptor 1 0.224558
PRELID2 PRELI domain containing 2 0.223143
TAS2R50 taste receptor, type 2, member 50 0.223143
ZNF343 zinc finger protein 343 0.223143
SPTY2D1 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) 0.223143
TBL2 transducin (beta)-like 2 0.222436
GPBAR1 G protein-coupled bile acid receptor 1 0.222083
MB myoglobin 0.221378
S100A8 S100 calcium binding protein A8 0.220321
PPAN peter pan homolog (Drosophila) 0.219969
CSF1R colony stimulating factor 1 receptor 0.218212
MTNR1B melatonin receptor 1B 0.217861
KLF2 Kruppel-like factor 2 0.217511
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.217511
DYNLL1 dynein, light chain, LC8-type 1 0.21716
CTSS cathepsin S 0.21716
AFP alpha-fetoprotein 0.21716
LYPLA1 lysophospholipase I 0.21646
CXCR2 chemokine (C-X-C motif) receptor 2 0.216111
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.214366
SLC22A18 solute carrier family 22, member 18 0.213322
ADIPOR2 adiponectin receptor 2 0.212974
GSTTP1 glutathione S-transferase theta pseudogene 1 0.21228
IGFBP1 insulin-like growth factor binding protein 1 0.21228
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.211933
APCS amyloid P component, serum 0.211587
TRIM37 tripartite motif containing 37 0.211587
LMF1 lipase maturation factor 1 0.21124
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.21124
GSTT1 glutathione S-transferase theta 1 0.209513
CHL1 cell adhesion molecule L1-like 0.209513
NAAA N-acylethanolamine acid amidase 0.209513
HNF4A hepatocyte nuclear factor 4, alpha 0.208825
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.208825
MMP12 matrix metallopeptidase 12 0.208481
PER3 period circadian clock 3 0.207108
FAM174A family with sequence similarity 174, member A 0.206766
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator 0.206766
MYBPHL myosin binding protein H-like 0.206766
CFAP44 cilia and flagella associated protein 44 0.206766
GPR25 G protein-coupled receptor 25 0.206766
GC group-specific component (vitamin D binding protein) 0.205399
SPP1 secreted phosphoprotein 1 0.204039
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.202684
TP53 tumor protein p53 0.201672
SP1 Sp1 transcription factor 0.200999
CCL3 chemokine (C-C motif) ligand 3 0.200328
IGLV2-14 immunoglobulin lambda variable 2-14 0.199993
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.199993
PCTP phosphatidylcholine transfer protein 0.198325
PRRC2A proline-rich coiled-coil 2A 0.197993
ATR ATR serine/threonine kinase 0.19733
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.19601
CXCL10 chemokine (C-X-C motif) ligand 10 0.19601
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.195681
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.193394
ARHGAP4 Rho GTPase activating protein 4 0.19307
SELL selectin L 0.192423
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 0.191456
MLN motilin 0.191135
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.189857
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.18796
GLT8D2 glycosyltransferase 8 domain containing 2 0.18796
SEBOX SEBOX homeobox 0.18796
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.179752
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.178877
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.177154
LGALS1 lectin, galactoside-binding, soluble, 1 0.17687
P4HB prolyl 4-hydroxylase, beta polypeptide 0.17687
CUTA cutA divalent cation tolerance homolog (E. coli) 0.176587
MAPK9 mitogen-activated protein kinase 9 0.176305
FHL1 four and a half LIM domains 1 0.173003
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 0.173003
OCLN occludin 0.172735
GPR171 G protein-coupled receptor 171 0.17141
APOA1BP apolipoprotein A-I binding protein 0.169859
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.168847
NPY neuropeptide Y 0.168847
ZCCHC16 zinc finger, CCHC domain containing 16 0.167366
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.167125
JPH3 junctophilin 3 0.166884
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.165697
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.16477
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.163641
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.16342
LST1 leukocyte specific transcript 1 0.1632
IL31RA interleukin 31 receptor A 0.162546
ARL8A ADP-ribosylation factor-like 8A 0.162117
CCDC92 coiled-coil domain containing 92 0.161905
ACTG1 actin gamma 1 0.161693
NPPA natriuretic peptide A 0.161484
TCHH trichohyalin 0.160456
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.160456
LPIN3 lipin 3 0.160053
GPR83 G protein-coupled receptor 83 0.159856
G6PC glucose-6-phosphatase, catalytic subunit 0.159856
OSBPL11 oxysterol binding protein-like 11 0.159658
JAK2 Janus kinase 2 0.159658
PDGFC platelet derived growth factor C 0.159268
IAPP islet amyloid polypeptide 0.159074
CTSB cathepsin B 0.159074
MAP9 microtubule-associated protein 9 0.158129
DNAH10 dynein, axonemal, heavy chain 10 0.132936
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.131835
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.130841
PCSK5 proprotein convertase subtilisin/kexin type 5 0.129411
A1CF APOBEC1 complementation factor 0.129072
CD5 CD5 molecule 0.123974
METTL7B methyltransferase like 7B 0.123317
SULF2 sulfatase 2 0.123307
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 0.123006
LRP10 low density lipoprotein receptor-related protein 10 0.122976
TM6SF2 transmembrane 6 superfamily member 2 0.122698
STAP2 signal transducing adaptor family member 2 0.12207
CROT carnitine O-octanoyltransferase 0.121994
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.120551
ACACB acetyl-CoA carboxylase beta 0.119776
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.119751
TSC22D4 TSC22 domain family, member 4 0.119094
PXDN peroxidasin 0.11874
VAMP7 vesicle-associated membrane protein 7 0.117923
CER1 cerberus 1, DAN family BMP antagonist 0.117572
CSTB cystatin B (stefin B) 0.117335
ZNHIT1 zinc finger, HIT-type containing 1 0.117304
RBP1 retinol binding protein 1, cellular 0.116722
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 0.11666
FAM83H family with sequence similarity 83, member H 0.116297
DAND5 DAN domain family member 5, BMP antagonist 0.11625
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.116122
DHRS7 dehydrogenase/reductase (SDR family) member 7 0.116058
BHMT betaine--homocysteine S-methyltransferase 0.115927
ACSL1 acyl-CoA synthetase long-chain family member 1 0.115566
ACSL3 acyl-CoA synthetase long-chain family member 3 0.115331
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 0.115197
ARFRP1 ADP-ribosylation factor related protein 1 0.115061
REPIN1 replication initiator 1 0.114489
RBP2 retinol binding protein 2, cellular 0.114189
OSBPL8 oxysterol binding protein-like 8 0.113348
FRMD5 FERM domain containing 5 0.112915
PSAT1 phosphoserine aminotransferase 1 0.111378
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.109795
JMJD1C jumonji domain containing 1C 0.108905
ELOVL5 ELOVL fatty acid elongase 5 0.108425
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.107654
TSKU tsukushi, small leucine rich proteoglycan 0.1072
ARL5A ADP-ribosylation factor-like 5A 0.106642
WRAP73 WD repeat containing, antisense to TP73 0.106418
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.10602
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 0.105487
ALPI alkaline phosphatase, intestinal 0.105436
RBP5 retinol binding protein 5, cellular 0.105153
ARL1 ADP-ribosylation factor-like 1 0.104737
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.104155
BTNL2 butyrophilin-like 2 0.103237
INSM2 insulinoma-associated 2 0.102378
GML glycosylphosphatidylinositol anchored molecule like 0.102208
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 0.101583
HDX highly divergent homeobox 0.10138
PRKCD protein kinase C, delta 0.100741
GOSR1 golgi SNAP receptor complex member 1 0.100029
SEC23IP SEC23 interacting protein 0.099274
WFDC2 WAP four-disulfide core domain 2 0.099183
CALCOCO2 calcium binding and coiled-coil domain 2 0.098629
DLX3 distal-less homeobox 3 0.098443
BET1 Bet1 golgi vesicular membrane trafficking protein 0.098132
FBXO44 F-box protein 44 0.098101
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 0.097691
DMBX1 diencephalon/mesencephalon homeobox 1 0.097533
IGBP1 immunoglobulin (CD79A) binding protein 1 0.096765
C4BPA complement component 4 binding protein, alpha 0.096279
GMPR guanosine monophosphate reductase 0.096279
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.095951
SBF2 SET binding factor 2 0.095755
PCCB propionyl CoA carboxylase, beta polypeptide 0.09489
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 0.09479
SEC24B SEC24 family member B 0.094756
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.09469
TMPRSS15 transmembrane protease, serine 15 0.094452
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.093427
JTB jumping translocation breakpoint 0.093185
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 0.093047
HIBADH 3-hydroxyisobutyrate dehydrogenase 0.092206
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 0.091533
PHEX phosphate regulating endopeptidase homolog, X-linked 0.091318
HRASLS5 HRAS-like suppressor family, member 5 0.091104
ERN2 endoplasmic reticulum to nucleus signaling 2 0.090854
KLHL12 kelch-like family member 12 0.090781
ZNF202 zinc finger protein 202 0.09009
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.089981
CCK cholecystokinin 0.089725
HES6 hes family bHLH transcription factor 6 0.089281
SPAG11A sperm associated antigen 11A 0.089134
TRIM47 tripartite motif containing 47 0.088912
MSRA methionine sulfoxide reductase A 0.088126
MALL mal, T-cell differentiation protein-like 0.087788
MXD4 MAX dimerization protein 4 0.087674
FAM65B family with sequence similarity 65, member B 0.087636
TMEM57 transmembrane protein 57 0.087255
LDHD lactate dehydrogenase D 0.087217
ACAT2 acetyl-CoA acetyltransferase 2 0.087141
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 0.087103
MIR146A microRNA 146a 0.086684
SPAG11B sperm associated antigen 11B 0.086645
SEC13 SEC13 homolog (S. cerevisiae) 0.086568
CLEC3B C-type lectin domain family 3, member B 0.086529
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.086491
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.086375
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.086298
STAP1 signal transducing adaptor family member 1 0.086259
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 0.086259
SP6 Sp6 transcription factor 0.086259
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.086182
GHSR growth hormone secretagogue receptor 0.085873
SLC35E2B solute carrier family 35, member E2B 0.085758
PLA2G2F phospholipase A2, group IIF 0.085758
GYS1 glycogen synthase 1 (muscle) 0.08568
LY6D lymphocyte antigen 6 complex, locus D 0.085602
ANOS1 anosmin 1 0.085563
HAMP hepcidin antimicrobial peptide 0.085406
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 0.085328
TG thyroglobulin 0.085289
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 0.085211
NDP Norrie disease (pseudoglioma) 0.085132
MMP28 matrix metallopeptidase 28 0.085093
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.085054
MIB2 mindbomb E3 ubiquitin protein ligase 2 0.084976
APC2 adenomatosis polyposis coli 2 0.084702
PLA2G5 phospholipase A2, group V 0.084702
LEF1 lymphoid enhancer-binding factor 1 0.084505
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.084465
C1QTNF9 C1q and tumor necrosis factor related protein 9 0.084465
IGLV1-50 immunoglobulin lambda variable 1-50 (non-functional) 0.084426
C4B complement component 4B (Chido blood group) 0.084188
CCL13 chemokine (C-C motif) ligand 13 0.084029
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 0.08395
CMC2 C-x(9)-C motif containing 2 0.083831
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 0.083752
DDIT4L DNA-damage-inducible transcript 4-like 0.083752
CARTPT CART prepropeptide 0.083594
M6PR mannose-6-phosphate receptor (cation dependent) 0.083594