pick body Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Cellular inclusion composed of numerous tau fibrils arranged in a disorderly array. Tau protein is a major component, though Pick bodies also contain ubiquitin, alpha-synuclein, and apolipoprotein E. (Gene Ontology, GO_0097419)
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Genes

47 proteins co-occuring with the pick body cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
MAPT microtubule-associated protein tau 1.96427
TSPO translocator protein (18kDa) 1.25917
SLC30A6 solute carrier family 30 (zinc transporter), member 6 1.16696
RD3 retinal degeneration 3 1.11684
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 1.08323
PHF1 PHD finger protein 1 0.951142
TARDBP TAR DNA binding protein 0.90739
GRN granulin 0.71768
OPTN optineurin 0.637578
PRND prion protein 2 (dublet) 0.602752
MSI1 musashi RNA-binding protein 1 0.598538
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.567169
CSNK1D casein kinase 1, delta 0.547297
PSEN1 presenilin 1 0.537005
DGKZ diacylglycerol kinase, zeta 0.518165
UBQLN2 ubiquilin 2 0.51164
GSK3A glycogen synthase kinase 3 alpha 0.4676
C9ORF72 chromosome 9 open reading frame 72 0.457208
SCG2 secretogranin II 0.399751
FUS FUS RNA binding protein 0.386208
CHMP2B charged multivesicular body protein 2B 0.374283
FIG4 FIG4 phosphoinositide 5-phosphatase 0.356324
SNCB synuclein, beta 0.354802
APOE apolipoprotein E 0.351382
VCP valosin containing protein 0.323825
APP amyloid beta (A4) precursor protein 0.317082
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.310732
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.291417
CHGA chromogranin A 0.274468
PARK7 parkinson protein 7 0.274468
MAP4 microtubule-associated protein 4 0.266774
DPYSL2 dihydropyrimidinase-like 2 0.255834
CD59 CD59 molecule, complement regulatory protein 0.250751
CHAT choline O-acetyltransferase 0.246046
HTT huntingtin 0.242797
MDK midkine (neurite growth-promoting factor 2) 0.241356
WARS tryptophanyl-tRNA synthetase 0.231672
UBC ubiquitin C 0.218563
CHKA choline kinase alpha 0.21124
ADRBK1 adrenergic, beta, receptor kinase 1 0.203022
CA13 carbonic anhydrase XIII 0.201335
RPS27A ribosomal protein S27a 0.197993
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.195025
UBB ubiquitin B 0.185469
MAP2 microtubule-associated protein 2 0.175745
SST somatostatin 0.173003
ELANE elastase, neutrophil expressed 0.163641