phthalylsulfathiazole-3371 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the phthalylsulfathiazole-3371 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ADGRA2 adhesion G protein-coupled receptor A2
ADGRL1 adhesion G protein-coupled receptor L1
AGFG1 ArfGAP with FG repeats 1
AHSG alpha-2-HS-glycoprotein
AKAP6 A kinase (PRKA) anchor protein 6
APC2 adenomatosis polyposis coli 2
APOM apolipoprotein M
ARMC4 armadillo repeat containing 4
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BAIAP3 BAI1-associated protein 3
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BIRC7 baculoviral IAP repeat containing 7
C10ORF12 chromosome 10 open reading frame 12
C22ORF46 chromosome 22 open reading frame 46
C8ORF17 chromosome 8 open reading frame 17
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEP152 centrosomal protein 152kDa
CEP41 centrosomal protein 41kDa
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CTSZ cathepsin Z
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
DAO D-amino-acid oxidase
DAPK2 death-associated protein kinase 2
DGCR8 DGCR8 microprocessor complex subunit
ELSPBP1 epididymal sperm binding protein 1
EPHB2 EPH receptor B2
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV4 ets variant 4
F5 coagulation factor V (proaccelerin, labile factor)
FBXO21 F-box protein 21
FRK fyn-related Src family tyrosine kinase
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GPER1 G protein-coupled estrogen receptor 1
GPR20 G protein-coupled receptor 20
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HMGA2 high mobility group AT-hook 2
HOXA11 homeobox A11
HOXC4 homeobox C4
HR hair growth associated
IGLJ3 immunoglobulin lambda joining 3
IGSF6 immunoglobulin superfamily, member 6
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM4B lysine (K)-specific demethylase 4B
KIF5A kinesin family member 5A
KLRD1 killer cell lectin-like receptor subfamily D, member 1
LMNA lamin A/C
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MKL1 megakaryoblastic leukemia (translocation) 1
MMP11 matrix metallopeptidase 11
MMP19 matrix metallopeptidase 19
MMP3 matrix metallopeptidase 3
MOCS1 molybdenum cofactor synthesis 1
MRPL41 mitochondrial ribosomal protein L41
MSX2 msh homeobox 2
MT3 metallothionein 3
MX1 MX dynamin-like GTPase 1
MYOG myogenin (myogenic factor 4)
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PDE4DIP phosphodiesterase 4D interacting protein
PENK proenkephalin
PEX3 peroxisomal biogenesis factor 3
PIP prolactin-induced protein
PIPOX pipecolic acid oxidase
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRB protein tyrosine phosphatase, receptor type, B
RAB40C RAB40C, member RAS oncogene family
RAI2 retinoic acid induced 2
REPS1 RALBP1 associated Eps domain containing 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPLP2 ribosomal protein, large, P2
RUNX1 runt-related transcription factor 1
SAG S-antigen; retina and pineal gland (arrestin)
SARM1 sterile alpha and TIR motif containing 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SMG7-AS1 SMG7 antisense RNA 1
SNW1 SNW domain containing 1
SPP1 secreted phosphoprotein 1
SULT4A1 sulfotransferase family 4A, member 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYN3 synapsin III
TAGLN3 transgelin 3
TBXA2R thromboxane A2 receptor
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TKTL1 transketolase-like 1
TPMT thiopurine S-methyltransferase
TRIM29 tripartite motif containing 29
TRPM3 transient receptor potential cation channel, subfamily M, member 3

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ANP32A-IT1 ANP32A intronic transcript 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ATHL1 ATH1, acid trehalase-like 1 (yeast)
AUTS2 autism susceptibility candidate 2
BPHL biphenyl hydrolase-like (serine hydrolase)
C11ORF63 chromosome 11 open reading frame 63
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC186 coiled-coil domain containing 186
CCNK cyclin K
CD82 CD82 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLDND1 claudin domain containing 1
CUZD1 CUB and zona pellucida-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DEAF1 DEAF1 transcription factor
DIXDC1 DIX domain containing 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DTX2 deltex 2, E3 ubiquitin ligase
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EPHX2 epoxide hydrolase 2, cytoplasmic
FAM131A family with sequence similarity 131, member A
FKBP5 FK506 binding protein 5
GAMT guanidinoacetate N-methyltransferase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L galactosidase, beta 1-like
GMPR guanosine monophosphate reductase
GPATCH2L G patch domain containing 2-like
GPR27 G protein-coupled receptor 27
GRTP1 growth hormone regulated TBC protein 1
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H4F histone cluster 1, H4f
HMOX1 heme oxygenase 1
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IGFBP6 insulin-like growth factor binding protein 6
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LIN7A lin-7 homolog A (C. elegans)
LY6D lymphocyte antigen 6 complex, locus D
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MOCS3 molybdenum cofactor synthesis 3
MORC3 MORC family CW-type zinc finger 3
MTCP1 mature T-cell proliferation 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NHEJ1 nonhomologous end-joining factor 1
NPFFR1 neuropeptide FF receptor 1
ODF2 outer dense fiber of sperm tails 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSMR oncostatin M receptor
PDIA3 protein disulfide isomerase family A, member 3
PHACTR4 phosphatase and actin regulator 4
PHF14 PHD finger protein 14
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMP22 peripheral myelin protein 22
PODNL1 podocan-like 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCAN3 RCAN family member 3
RHBG Rh family, B glycoprotein (gene/pseudogene)
ROM1 retinal outer segment membrane protein 1
RPL10L ribosomal protein L10-like
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERGEF secretion regulating guanine nucleotide exchange factor
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC46A3 solute carrier family 46, member 3
SLMO1 slowmo homolog 1 (Drosophila)
STRN striatin, calmodulin binding protein
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYTL2 synaptotagmin-like 2
TARP TCR gamma alternate reading frame protein
TBC1D2 TBC1 domain family, member 2
TEP1 telomerase-associated protein 1
TTLL1 tubulin tyrosine ligase-like family member 1
UPP1 uridine phosphorylase 1
WDR76 WD repeat domain 76
XYLT2 xylosyltransferase II
ZBTB6 zinc finger and BTB domain containing 6
ZFHX2 zinc finger homeobox 2
ZIC3 Zic family member 3
ZNF134 zinc finger protein 134
ZNF230 zinc finger protein 230
ZNF286A zinc finger protein 286A
ZNF394 zinc finger protein 394
ZNF639 zinc finger protein 639
ZSCAN2 zinc finger and SCAN domain containing 2