photoreceptor outer segment Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The outer segment of a vertebrate photoreceptor that contains discs of photoreceptive membranes. (Gene Ontology, GO_0001750)
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Genes

170 proteins co-occuring with the photoreceptor outer segment cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
RHO rhodopsin 2.17199
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1.98692
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 1.84497
MERTK MER proto-oncogene, tyrosine kinase 1.81042
ROM1 retinal outer segment membrane protein 1 1.80573
RPE65 retinal pigment epithelium-specific protein 65kDa 1.64314
GUCA1B guanylate cyclase activator 1B (retina) 1.57416
PRPH2 peripherin 2 (retinal degeneration, slow) 1.53444
PRCD progressive rod-cone degeneration 1.52202
BEST1 bestrophin 1 1.36472
RCVRN recoverin 1.34938
RBP3 retinol binding protein 3, interstitial 1.32005
RLBP1 retinaldehyde binding protein 1 1.24602
GUCY2C guanylate cyclase 2C 1.18543
GRK1 G protein-coupled receptor kinase 1 1.18389
NPR1 natriuretic peptide receptor 1 1.14955
NRL neural retina leucine zipper 1.07968
CRX cone-rod homeobox 1.06448
RDH8 retinol dehydrogenase 8 (all-trans) 1.06195
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 1.00054
IMPG2 interphotoreceptor matrix proteoglycan 2 0.972747
DHDDS dehydrodolichyl diphosphate synthase 0.958789
IFT57 intraflagellar transport 57 0.954483
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 0.944482
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 0.943059
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 0.934072
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 0.916709
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7 0.899499
CNGB1 cyclic nucleotide gated channel beta 1 0.88286
MYO7A myosin VIIA 0.880094
CTSD cathepsin D 0.873186
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.856176
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 0.834597
GAS6 growth arrest-specific 6 0.826336
RPGR retinitis pigmentosa GTPase regulator 0.825418
RGS9BP regulator of G protein signaling 9 binding protein 0.823582
MFGE8 milk fat globule-EGF factor 8 protein 0.82037
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 0.792396
ELOVL4 ELOVL fatty acid elongase 4 0.770907
PCDH15 protocadherin-related 15 0.746381
CERKL ceramide kinase-like 0.739163
SAG S-antigen; retina and pineal gland (arrestin) 0.727047
RP1L1 retinitis pigmentosa 1-like 1 0.712351
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 0.701304
SUSD4 sushi domain containing 4 0.699983
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 0.694709
IFT20 intraflagellar transport 20 0.692955
ASMT acetylserotonin O-methyltransferase 0.690326
TMEM237 transmembrane protein 237 0.690326
NCALD neurocalcin delta 0.688576
SCARB1 scavenger receptor class B, member 1 0.683771
IFT88 intraflagellar transport 88 0.680719
CNGB3 cyclic nucleotide gated channel beta 3 0.653019
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.628187
FRMD6 FERM domain containing 6 0.622654
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 0.620104
KIF17 kinesin family member 17 0.61968
SCARB2 scavenger receptor class B, member 2 0.60444
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 0.587618
CDHR1 cadherin-related family member 1 0.584686
CD36 CD36 molecule (thrombospondin receptor) 0.58134
RRH retinal pigment epithelium-derived rhodopsin homolog 0.575912
RD3 retinal degeneration 3 0.572994
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.568001
IFT52 intraflagellar transport 52 0.553078
AHI1 Abelson helper integration site 1 0.552664
CNGA3 cyclic nucleotide gated channel alpha 3 0.548122
GUCA2A guanylate cyclase activator 2A (guanylin) 0.54606
CFH complement factor H 0.545236
POC1B POC1 centriolar protein B 0.529618
PDC phosducin 0.52675
CDH23 cadherin-related 23 0.51164
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 0.510418
CHM choroideremia (Rab escort protein 1) 0.498231
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.480453
RGS9 regulator of G-protein signaling 9 0.477233
GUCA1A guanylate cyclase activator 1A (retina) 0.469203
USH1C Usher syndrome 1C (autosomal recessive, severe) 0.465198
FAM161A family with sequence similarity 161, member A 0.440916
ADAM9 ADAM metallopeptidase domain 9 0.429072
KIF3B kinesin family member 3B 0.421997
OXR1 oxidation resistance 1 0.419252
LCA5 Leber congenital amaurosis 5 0.416902
TTLL6 tubulin tyrosine ligase-like family member 6 0.414946
RP2 retinitis pigmentosa 2 (X-linked recessive) 0.409869
MREG melanoregulin 0.405971
GLUL glutamate-ammonia ligase 0.397811
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.393549
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.37966
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.375818
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.373132
FGF13 fibroblast growth factor 13 0.369301
NCAN neurocan 0.367388
IFT80 intraflagellar transport 80 0.364331
RTN2 reticulon 2 0.36204
AANAT aralkylamine N-acetyltransferase 0.360896
FGFRL1 fibroblast growth factor receptor-like 1 0.357467
KIF3C kinesin family member 3C 0.350243
CRYBA1 crystallin, beta A1 0.347967
VEGFA vascular endothelial growth factor A 0.347587
S100A1 S100 calcium binding protein A1 0.345692
ITGA8 integrin, alpha 8 0.342664
MFRP membrane frizzled-related protein 0.342285
PRPF31 pre-mRNA processing factor 31 0.337751
USH1G Usher syndrome 1G (autosomal recessive) 0.337751
VIPR2 vasoactive intestinal peptide receptor 2 0.335487
IFT140 intraflagellar transport 140 0.332472
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 0.330966
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.3227
FGFR4 fibroblast growth factor receptor 4 0.321201
CC2D2A coiled-coil and C2 domain containing 2A 0.319702
UNC119 unc-119 homolog (C. elegans) 0.316334
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 0.314465
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.305888
GRB14 growth factor receptor-bound protein 14 0.302912
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.284769
GFAP glial fibrillary acidic protein 0.283295
C3 complement component 3 0.281085
RBP1 retinol binding protein 1, cellular 0.279612
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 0.278509
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.276671
NUB1 negative regulator of ubiquitin-like proteins 1 0.275202
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 0.273367
RGS11 regulator of G-protein signaling 11 0.272633
TUBGCP4 tubulin, gamma complex associated protein 4 0.265677
MYO3A myosin IIIA 0.265677
TTC8 tetratricopeptide repeat domain 8 0.25547
RGS6 regulator of G-protein signaling 6 0.252927
FGFR2 fibroblast growth factor receptor 2 0.250026
FGF2 fibroblast growth factor 2 (basic) 0.246769
PARD3 par-3 family cell polarity regulator 0.245685
ARR3 arrestin 3, retinal (X-arrestin) 0.242076
S100B S100 calcium binding protein B 0.241716
TADA3 transcriptional adaptor 3 0.239916
IFT172 intraflagellar transport 172 0.238837
FTCD formimidoyltransferase cyclodeaminase 0.234891
PLA2G5 phospholipase A2, group V 0.230601
CLN3 ceroid-lipofuscinosis, neuronal 3 0.229532
FGFR1 fibroblast growth factor receptor 1 0.228108
MATN3 matrilin 3 0.220321
PPT1 palmitoyl-protein thioesterase 1 0.207794
ELANE elastase, neutrophil expressed 0.203361
RAB8A RAB8A, member RAS oncogene family 0.201672
ALB albumin 0.200663
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 0.198658
NPHP4 nephronophthisis 4 0.198658
FGFR3 fibroblast growth factor receptor 3 0.196339
RAB18 RAB18, member RAS oncogene family 0.194045
SPTBN2 spectrin, beta, non-erythrocytic 2 0.192423
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.192423
PRPF3 pre-mRNA processing factor 3 0.192423
CLIC4 chloride intracellular channel 4 0.189222
BDNF brain-derived neurotrophic factor 0.185777
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.183025
CERK ceramide kinase 0.183025
RAB11B RAB11B, member RAS oncogene family 0.182723
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.182122
PRPF8 pre-mRNA processing factor 8 0.180339
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.175466
TEK TEK tyrosine kinase, endothelial 0.175188
DAND5 DAN domain family member 5, BMP antagonist 0.173814
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 0.173273
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.170371
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 0.168598
APOPT1 apoptogenic 1, mitochondrial 0.167611
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 0.16477
PROS1 protein S (alpha) 0.164089
SLC30A3 solute carrier family 30 (zinc transporter), member 3 0.162546
CETN1 centrin, EF-hand protein, 1 0.159074
RGS7 regulator of G-protein signaling 7 0.158129