phagolysosome Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes. (Gene Ontology, GO_0032010)
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Genes

195 proteins co-occuring with the phagolysosome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
LAMP1 lysosomal-associated membrane protein 1 1.54461
ACPP acid phosphatase, prostate 1.43218
CTSD cathepsin D 1.26815
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 1.21738
KRT83 keratin 83, type II 1.12041
RAB34 RAB34, member RAS oncogene family 1.12041
LAMP2 lysosomal-associated membrane protein 2 1.00942
FTL ferritin, light polypeptide 0.923259
EEA1 early endosome antigen 1 0.922322
FTH1 ferritin, heavy polypeptide 1 0.922322
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.915309
RILP Rab interacting lysosomal protein 0.873647
MPO myeloperoxidase 0.835056
NLRP3 NLR family, pyrin domain containing 3 0.818993
MRC1 mannose receptor, C type 1 0.801562
APOE apolipoprotein E 0.759069
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.751357
GUSB glucuronidase, beta 0.746833
MORN2 MORN repeat containing 2 0.711022
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.682027
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.680719
CTSL cathepsin L 0.670292
IRGM immunity-related GTPase family, M 0.656464
LYZ lysozyme 0.651729
DRG1 developmentally regulated GTP binding protein 1 0.651729
CAT catalase 0.642715
TFRC transferrin receptor 0.638005
HLA-B major histocompatibility complex, class I, B 0.632451
PI3 peptidase inhibitor 3, skin-derived 0.620954
EPX eosinophil peroxidase 0.617982
CTSB cathepsin B 0.597697
CTSS cathepsin S 0.596435
CD4 CD4 molecule 0.595173
CTSG cathepsin G 0.585523
ESX1 ESX homeobox 1 0.584268
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.572162
CD63 CD63 molecule 0.54771
PTBP2 polypyrimidine tract binding protein 2 0.546885
LPO lactoperoxidase 0.540294
RAB22A RAB22A, member RAS oncogene family 0.535361
FXYD1 FXYD domain containing ion transport regulator 1 0.530028
DEFA4 defensin, alpha 4, corticostatin 0.52675
SYTL1 synaptotagmin-like 1 0.525522
CLC Charcot-Leyden crystal galectin 0.49418
CARD17 caspase recruitment domain family, member 17 0.491348
TLR2 toll-like receptor 2 0.488923
HCK HCK proto-oncogene, Src family tyrosine kinase 0.485289
ALB albumin 0.481661
CD1B CD1b molecule 0.48005
ACP2 acid phosphatase 2, lysosomal 0.468802
TG thyroglobulin 0.463997
ZNF85 zinc finger protein 85 0.448054
CERK ceramide kinase 0.4425
CD1C CD1c molecule 0.437356
CARD9 caspase recruitment domain family, member 9 0.435775
FLOT1 flotillin 1 0.422389
TLR9 toll-like receptor 9 0.393549
WDR83 WD repeat domain 83 0.388909
PPA2 pyrophosphatase (inorganic) 2 0.382354
VAMP8 vesicle-associated membrane protein 8 0.376586
DNAH8 dynein, axonemal, heavy chain 8 0.365477
TNF tumor necrosis factor 0.364713
RBKS ribokinase 0.351762
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.349863
AQR aquarius intron-binding spliceosomal factor 0.349105
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 0.347967
EPGN epithelial mitogen 0.347208
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 0.345314
RAB5A RAB5A, member RAS oncogene family 0.340773
MEFV Mediterranean fever 0.335864
VTI1B vesicle transport through interaction with t-SNAREs 1B 0.331342
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.331342
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 0.329837
C7 complement component 7 0.328708
M6PR mannose-6-phosphate receptor (cation dependent) 0.327956
CD68 CD68 molecule 0.324201
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.319702
ATG9A autophagy related 9A 0.318953
RAB20 RAB20, member RAS oncogene family 0.313718
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.307004
CD209 CD209 molecule 0.302168
CTSC cathepsin C 0.300311
CAMP cathelicidin antimicrobial peptide 0.298826
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 0.297342
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.293637
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 0.28846
BEAN1 brain expressed, associated with NEDD4, 1 0.280716
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.27998
VAMP3 vesicle-associated membrane protein 3 0.278877
TF transferrin 0.275569
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.273367
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.273367
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.273
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 0.271533
RAB31 RAB31, member RAS oncogene family 0.267871
AKAP13 A kinase (PRKA) anchor protein 13 0.266042
SOD2 superoxide dismutase 2, mitochondrial 0.262025
RAP2B RAP2B, member of RAS oncogene family 0.25438
CD86 CD86 molecule 0.252564
NOS2 nitric oxide synthase 2, inducible 0.252564
TIMD4 T-cell immunoglobulin and mucin domain containing 4 0.250389
TMPRSS13 transmembrane protease, serine 13 0.249664
DCTN1 dynactin 1 0.248578
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.242076
DGKD diacylglycerol kinase, delta 130kDa 0.241716
EDA ectodysplasin A 0.240996
KIAA0226 KIAA0226 0.240996
AZU1 azurocidin 1 0.239557
RAB24 RAB24, member RAS oncogene family 0.236683
PGM1 phosphoglucomutase 1 0.233101
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.232386
HAVCR1 hepatitis A virus cellular receptor 1 0.231672
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.229532
BECN1 beclin 1, autophagy related 0.228464
HTRA1 HtrA serine peptidase 1 0.227041
ANXA2 annexin A2 0.227041
S100A9 S100 calcium binding protein A9 0.226686
BPI bactericidal/permeability-increasing protein 0.219265
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 0.219265
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.217861
RAB5B RAB5B, member RAS oncogene family 0.213669
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.212627
DHFR dihydrofolate reductase 0.21228
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.211933
APEH acylaminoacyl-peptide hydrolase 0.206423
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.206082
LXN latexin 0.203022
GNPDA1 glucosamine-6-phosphate deaminase 1 0.201335
SYK spleen tyrosine kinase 0.198658
MMP12 matrix metallopeptidase 12 0.194045
RAB7A RAB7A, member RAS oncogene family 0.194045
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.193719
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.193394
SNF8 SNF8, ESCRT-II complex subunit 0.188905
RBBP9 retinoblastoma binding protein 9 0.187646
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.184241
CD1E CD1e molecule 0.183935
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.181823
MIR210 microRNA 210 0.176587
CD40 CD40 molecule, TNF receptor superfamily member 5 0.175466
CAPN7 calpain 7 0.174911
NRD1 nardilysin (N-arginine dibasic convertase) 0.174361
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.173273
STX6 syntaxin 6 0.171149
CNTN3 contactin 3 (plasmacytoma associated) 0.169859
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.169099
RHO rhodopsin 0.168598
VSX1 visual system homeobox 1 0.167611
RAB21 RAB21, member RAS oncogene family 0.164315
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.161275
ALPPL2 alkaline phosphatase, placental-like 2 0.160456
ALPL alkaline phosphatase, liver/bone/kidney 0.160254
ALPP alkaline phosphatase, placental 0.160053
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.159856
HLA-DMA major histocompatibility complex, class II, DM alpha 0.158502
CLEC7A C-type lectin domain family 7, member A 0.158502
IL22 interleukin 22 0.157397
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.156513
ANTXR2 anthrax toxin receptor 2 0.156342
BLVRB biliverdin reductase B 0.148012
ANXA4 annexin A4 0.146486
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 0.146311
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 0.14449
VARS valyl-tRNA synthetase 0.144274
MTO1 mitochondrial tRNA translation optimization 1 0.143674
REEP5 receptor accessory protein 5 0.143527
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.143418
HPD 4-hydroxyphenylpyruvate dioxygenase 0.142786
FANCL Fanconi anemia, complementation group L 0.141979
LGMN legumain 0.141888
EPB41 erythrocyte membrane protein band 4.1 0.141799
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.141775
STOM stomatin 0.141735
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.14146
AMPD2 adenosine monophosphate deaminase 2 0.141413
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 0.141335
ATP11A ATPase, class VI, type 11A 0.14128
TPT1 tumor protein, translationally-controlled 1 0.140857
USP9X ubiquitin specific peptidase 9, X-linked 0.140707
TP53INP1 tumor protein p53 inducible nuclear protein 1 0.140554
DUT deoxyuridine triphosphatase 0.140432
G6PC glucose-6-phosphatase, catalytic subunit 0.14037
CTSE cathepsin E 0.140334
KRT9 keratin 9, type I 0.140262
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.139839
CAST calpastatin 0.138373
MRPS7 mitochondrial ribosomal protein S7 0.137972
REN renin 0.137658
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.13751
IDE insulin-degrading enzyme 0.136907
LARS leucyl-tRNA synthetase 0.136877
LAP3 leucine aminopeptidase 3 0.136338
ANXA6 annexin A6 0.136198
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.136071
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.13604