peripheral primitive neuroectodermal tumor Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A bone cancer that has_material_basis in neural crest cells derived_from undeveloped, undifferentiated neuroectoderm. (Human Disease Ontology, DOID_3369)
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Genes

234 genes co-occuring with the disease peripheral primitive neuroectodermal tumor in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
EWSR1 EWS RNA-binding protein 1 3.31547
FLI1 Fli-1 proto-oncogene, ETS transcription factor 2.70509
CD99 CD99 molecule 2.15302
CCNB3 cyclin B3 1.4856
ENO2 enolase 2 (gamma, neuronal) 1.46979
ATF1 activating transcription factor 1 1.39477
IGF1R insulin-like growth factor 1 receptor 1.37992
ETV1 ets variant 1 1.30532
ETV4 ets variant 4 1.2861
FUS FUS RNA binding protein 1.24472
DUX4L8 double homeobox 4 like 8 1.19921
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 1.19618
STEAP1 six transmembrane epithelial antigen of the prostate 1 1.16093
DUX4L6 double homeobox 4 like 6 1.1541
IGLC7 immunoglobulin lambda constant 7 1.12783
BCOR BCL6 corepressor 1.1051
WT1 Wilms tumor 1 1.09503
PRMT8 protein arginine methyltransferase 8 1.08537
SYP synaptophysin 1.0732
FLII flightless I homolog (Drosophila) 1.05765
STAG2 stromal antigen 2 1.02355
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.97296
ZNF43 zinc finger protein 43 0.966663
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.966663
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 0.953273
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 0.914315
B3GAT1 beta-1,3-glucuronyltransferase 1 0.902799
PAX3 paired box 3 0.859362
CEP41 centrosomal protein 41kDa 0.849536
C21ORF33 chromosome 21 open reading frame 33 0.830689
STRAP serine/threonine kinase receptor associated protein 0.823718
NCAM1 neural cell adhesion molecule 1 0.818385
ECHDC2 enoyl CoA hydratase domain containing 2 0.797462
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.785984
DVL2 dishevelled segment polarity protein 2 0.782298
MYOG myogenin (myogenic factor 4) 0.779841
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.766351
U2AF2 U2 small nuclear RNA auxiliary factor 2 0.759824
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1 0.753713
STEAP2 STEAP family member 2, metalloreductase 0.741923
IGF1 insulin-like growth factor 1 (somatomedin C) 0.726929
EYA3 EYA transcriptional coactivator and phosphatase 3 0.72612
FZD3 frizzled class receptor 3 0.722077
ABLIM1 actin binding LIM protein 1 0.715618
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.703134
LRRC15 leucine rich repeat containing 15 0.701124
SS18 synovial sarcoma translocation, chromosome 18 0.696306
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.695103
BCR breakpoint cluster region 0.684292
INSRR insulin receptor-related receptor 0.677903
BAIAP3 BAI1-associated protein 3 0.664372
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.65763
NUTM1 NUT midline carcinoma, family member 1 0.657234
GLI1 GLI family zinc finger 1 0.655254
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.652089
TP53 tumor protein p53 0.648928
DVL1 dishevelled segment polarity protein 1 0.64577
TARBP2 TAR (HIV-1) RNA binding protein 2 0.645375
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.642221
STK26 serine/threonine protein kinase 26 0.642221
PTPRC protein tyrosine phosphatase, receptor type, C 0.630813
STK3 serine/threonine kinase 3 0.625711
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.621792
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 0.612792
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.609666
FOXO1 forkhead box O1 0.60264
CSDE1 cold shock domain containing E1, RNA-binding 0.597961
PAX7 paired box 7 0.587054
NFRKB nuclear factor related to kappaB binding protein 0.575383
WNT3A wingless-type MMTV integration site family, member 3A 0.56722
SFPQ splicing factor proline/glutamine-rich 0.55712
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.545093
PRMT1 protein arginine methyltransferase 1 0.544318
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.532314
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.526518
FANCL Fanconi anemia, complementation group L 0.524202
TRIM25 tripartite motif containing 25 0.520731
NTNG1 netrin G1 0.510728
WNT11 wingless-type MMTV integration site family, member 11 0.495793
GGTLC1 gamma-glutamyltransferase light chain 1 0.490454
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 0.48893
REST RE1-silencing transcription factor 0.485125
NES nestin 0.483985
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.482084
NKX2-2 NK2 homeobox 2 0.481705
NTNG2 netrin G2 0.480566
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.478668
MYOD1 myogenic differentiation 1 0.478289
FHOD1 formin homology 2 domain containing 1 0.468063
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.467684
ALK anaplastic lymphoma receptor tyrosine kinase 0.465416
STEAP4 STEAP family member 4 0.463905
FOXO4 forkhead box O4 0.456732
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.455601
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.452208
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.451078
CSF3 colony stimulating factor 3 (granulocyte) 0.449194
CD34 CD34 molecule 0.43941
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.434148
DGCR8 DGCR8 microprocessor complex subunit 0.433772
GSTM4 glutathione S-transferase mu 4 0.431519
SLC38A5 solute carrier family 38, member 5 0.42814
FBXO5 F-box protein 5 0.42589
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 0.425139
EHD1 EH-domain containing 1 0.423265
CDKN2A cyclin-dependent kinase inhibitor 2A 0.422515
TNPO1 transportin 1 0.421765
GFAP glial fibrillary acidic protein 0.421016
CCND1 cyclin D1 0.419892
PRMT3 protein arginine methyltransferase 3 0.41465
PRKCB protein kinase C, beta 0.412779
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.412031
VIT vitrin 0.410161
ZMYM3 zinc finger, MYM-type 3 0.409414
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.407919
CALCB calcitonin-related polypeptide beta 0.406798
CREB3L1 cAMP responsive element binding protein 3-like 1 0.395235
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 0.394491
THY1 Thy-1 cell surface antigen 0.392257
SALL2 spalt-like transcription factor 2 0.392257
STEAP3 STEAP family member 3, metalloreductase 0.388909
PIDD1 p53-induced death domain protein 1 0.388538
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.388166
BRD4 bromodomain containing 4 0.383708
SLAMF6 SLAM family member 6 0.382223
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.378143
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 0.37629
KDM1A lysine (K)-specific demethylase 1A 0.370368
USP6 ubiquitin specific peptidase 6 0.369628
IGLL1 immunoglobulin lambda-like polypeptide 1 0.368518
DLL4 delta-like 4 (Drosophila) 0.36704
ALPPL2 alkaline phosphatase, placental-like 2 0.354868
ALPP alkaline phosphatase, placental 0.354131
ALPL alkaline phosphatase, liver/bone/kidney 0.353763
SSX1 synovial sarcoma, X breakpoint 1 0.348614
RHD Rh blood group, D antigen 0.346409
DRAM1 DNA-damage regulated autophagy modulator 1 0.345675
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.343473
IGKV1D-42 immunoglobulin kappa variable 1D-42 (non-functional) 0.33066
CD226 CD226 molecule 0.321909
RYK receptor-like tyrosine kinase 0.321545
LRP6 low density lipoprotein receptor-related protein 6 0.320454
PAX8 paired box 8 0.317909
CENPV centromere protein V 0.310652
CDAN1 codanin 1 0.307757
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.304864
JUN jun proto-oncogene 0.300894
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.298731
DNA2 DNA replication helicase/nuclease 2 0.295132
CTHRC1 collagen triple helix repeat containing 1 0.28831
APOL6 apolipoprotein L, 6 0.284371
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.277227
EGFR epidermal growth factor receptor 0.276158
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.273308
MAP2K1 mitogen-activated protein kinase kinase 1 0.271886
CAV1 caveolin 1, caveolae protein, 22kDa 0.266558
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.266558
XAGE1E X antigen family, member 1E 0.264431
TSPAN7 tetraspanin 7 0.263368
LIF leukemia inhibitory factor 0.261599
DVL3 dishevelled segment polarity protein 3 0.258417
ERBB4 erb-b2 receptor tyrosine kinase 4 0.258064
DUSP5 dual specificity phosphatase 5 0.254183
PHF11 PHD finger protein 11 0.254183
XAGE1B X antigen family, member 1B 0.253479
PDGFB platelet-derived growth factor beta polypeptide 0.253479
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.25207
NEFH neurofilament, heavy polypeptide 0.251015
PIR pirin (iron-binding nuclear protein) 0.250311
MGST1 microsomal glutathione S-transferase 1 0.248203
KIF1A kinesin family member 1A 0.245747
MYF6 myogenic factor 6 (herculin) 0.245396
SOX6 SRY (sex determining region Y)-box 6 0.245046
CELA2A chymotrypsin-like elastase family, member 2A 0.244345
MLF1 myeloid leukemia factor 1 0.241895
CDK8 cyclin-dependent kinase 8 0.241546
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 0.239101
E2F3 E2F transcription factor 3 0.238403
IGFBP3 insulin-like growth factor binding protein 3 0.237706
CENPE centromere protein E, 312kDa 0.237706
IGF2 insulin-like growth factor 2 0.234573
NNAT neuronatin 0.231795
ULBP2 UL16 binding protein 2 0.225573
PDS5B PDS5 cohesin associated factor B 0.222479
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.22145
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.220424
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.215314
AURKA aurora kinase A 0.212945
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.212608
SMC1A structural maintenance of chromosomes 1A 0.210589
CREB1 cAMP responsive element binding protein 1 0.207245
PARD6A par-6 family cell polarity regulator alpha 0.204593
PCP2 Purkinje cell protein 2 0.203933
ARAF A-Raf proto-oncogene, serine/threonine kinase 0.20229
AURKB aurora kinase B 0.199356
CDC6 cell division cycle 6 0.1936
CD248 CD248 molecule, endosialin 0.192971
ZYX zyxin 0.192971
WNT2B wingless-type MMTV integration site family, member 2B 0.188632
SMC3 structural maintenance of chromosomes 3 0.187113
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.18591
DES desmin 0.18591
WNT5A wingless-type MMTV integration site family, member 5A 0.185313
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.182086
DNTT DNA nucleotidylexotransferase 0.182086
TH tyrosine hydroxylase 0.179802
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.179239
DPP9 dipeptidyl-peptidase 9 0.176485
PROM1 prominin 1 0.175947
TOP1 topoisomerase (DNA) I 0.174093
PTPRD protein tyrosine phosphatase, receptor type, D 0.174093
ERBB3 erb-b2 receptor tyrosine kinase 3 0.170789
ETV5 ets variant 5 0.168617
SSB Sjogren syndrome antigen B (autoantigen La) 0.168381
RAD21 RAD21 homolog (S. pombe) 0.165874
EIF4E eukaryotic translation initiation factor 4E 0.165001
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.165001
TPRG1L tumor protein p63 regulated 1-like 0.164571
LSP1 lymphocyte-specific protein 1 0.164149
NOV nephroblastoma overexpressed 0.162908
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 0.160948
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.160761
HDGF hepatoma-derived growth factor 0.159838
TAPBP TAP binding protein (tapasin) 0.159302
PLD2 phospholipase D2 0.159124
MYF5 myogenic factor 5 0.144359
SCN2A sodium channel, voltage gated, type II alpha subunit 0.142078
BSG basigin (Ok blood group) 0.141764
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.139779
LCK LCK proto-oncogene, Src family tyrosine kinase 0.139226
ADA adenosine deaminase 0.1381
FGF2 fibroblast growth factor 2 (basic) 0.130426
HLA-A major histocompatibility complex, class I, A 0.128715
B2M beta-2-microglobulin 0.126631