peripheral primitive neuroectodermal tumor cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description One of a remarkable group of tumors that originate in cells from the primitive neural crest and share the same reciprocal translocation between chromosomes 11 and 22 and the same patterns of biochemical and oncogene expression. Some primitive neuroectodermal tumors (PNETs) occur in the brain while others (the peripheral PNETs) occur in sites outside the brain such as in the extremities, pelvis, and the chest wall. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004261)
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Genes

70 proteins co-occuring with the tissue peripheral primitive neuroectodermal tumor cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
EWSR1 EWS RNA-binding protein 1 1.49302
SIM1 single-minded family bHLH transcription factor 1 1.17891
CD99 CD99 molecule 0.95988
ITGA6 integrin, alpha 6 0.844965
GLI1 GLI family zinc finger 1 0.646911
GLYCTK glycerate kinase 0.564035
NF1 neurofibromin 1 0.551695
FAM84B family with sequence similarity 84, member B 0.547922
PTCH1 patched 1 0.546533
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.519647
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.498636
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.459918
MIR186 microRNA 186 0.456442
GRP gastrin-releasing peptide 0.420004
PROM1 prominin 1 0.41848
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.391176
SHH sonic hedgehog 0.373118
CFLAR CASP8 and FADD-like apoptosis regulator 0.372556
CD177 CD177 molecule 0.35836
TRIB1 tribbles pseudokinase 1 0.356686
KIF1A kinesin family member 1A 0.337072
PLA2G1B phospholipase A2, group IB (pancreas) 0.32497
VIPR2 vasoactive intestinal peptide receptor 2 0.321138
SCG2 secretogranin II 0.312232
KIF1B kinesin family member 1B 0.31024
PCCA propionyl CoA carboxylase, alpha polypeptide 0.25858
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.251934
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.243139
MTSS1 metastasis suppressor 1 0.241592
PDGFC platelet derived growth factor C 0.231621
HRAS Harvey rat sarcoma viral oncogene homolog 0.229032
CGB7 chorionic gonadotropin, beta polypeptide 7 0.226283
CGB5 chorionic gonadotropin, beta polypeptide 5 0.225018
DMBT1 deleted in malignant brain tumors 1 0.220604
CGB chorionic gonadotropin, beta polypeptide 0.22004
CGB8 chorionic gonadotropin, beta polypeptide 8 0.219707
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.210369
VEGFB vascular endothelial growth factor B 0.206715
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.205348
CHGB chromogranin B 0.202625
DCXR dicarbonyl/L-xylulose reductase 0.201075
FGFR2 fibroblast growth factor receptor 2 0.20072
FGFR1 fibroblast growth factor receptor 1 0.200159
VIPR1 vasoactive intestinal peptide receptor 1 0.199595
IGF1R insulin-like growth factor 1 receptor 0.199408
MAP1B microtubule-associated protein 1B 0.199032
SFRP1 secreted frizzled-related protein 1 0.198162
NEFM neurofilament, medium polypeptide 0.198033
ENO2 enolase 2 (gamma, neuronal) 0.197808
FHIT fragile histidine triad 0.197522
CHGA chromogranin A 0.19743
TP53 tumor protein p53 0.197299
TNIP1 TNFAIP3 interacting protein 1 0.196924
NEFH neurofilament, heavy polypeptide 0.196865
PIDD1 p53-induced death domain protein 1 0.19634
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.196279
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.196249
S100A4 S100 calcium binding protein A4 0.196095
NGF nerve growth factor (beta polypeptide) 0.19596
PI3 peptidase inhibitor 3, skin-derived 0.195607
NRG1 neuregulin 1 0.195133
CDKN2A cyclin-dependent kinase inhibitor 2A 0.195016
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.194479
FADD Fas (TNFRSF6)-associated via death domain 0.19393
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.193286
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.192256
MAP4 microtubule-associated protein 4 0.192109
FOS FBJ murine osteosarcoma viral oncogene homolog 0.190524
TGFB3 transforming growth factor, beta 3 0.190271
PDPN podoplanin 0.190172