periodontal ligament Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The fibrous connective tissue that surrounds the root of a tooth, separating it from and attaching it to the alveolar bone. It extends from the base of the gingival mucosa to the fundus of the bony socket, and its main function is to hold the tooth in its socket. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001020)
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Genes

249 proteins co-occuring with the tissue periodontal ligament in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
ALPL alkaline phosphatase, liver/bone/kidney 2.19875
IBSP integrin-binding sialoprotein 2.19664
ALPP alkaline phosphatase, placental 2.1919
ALPPL2 alkaline phosphatase, placental-like 2 2.1919
BGLAP bone gamma-carboxyglutamate (gla) protein 2.04979
SPP1 secreted phosphoprotein 1 2.04551
HACD1 3-hydroxyacyl-CoA dehydratase 1 1.98313
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.97995
RUNX2 runt-related transcription factor 2 1.9773
CEMP1 cementum protein 1 1.94725
BMP2 bone morphogenetic protein 2 1.87805
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.70296
AMELY amelogenin, Y-linked 1.6126
AMELX amelogenin, X-linked 1.60068
MMP1 matrix metallopeptidase 1 1.4949
SP7 Sp7 transcription factor 1.47709
FN1 fibronectin 1 1.41445
FDCSP follicular dendritic cell secreted protein 1.35813
ACPP acid phosphatase, prostate 1.35495
FGF2 fibroblast growth factor 2 (basic) 1.33591
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.32867
IL1B interleukin 1, beta 1.32732
MCAM melanoma cell adhesion molecule 1.28502
BMP7 bone morphogenetic protein 7 1.25101
TGFB1 transforming growth factor, beta 1 1.21579
ASPN asporin 1.21179
FBN1 fibrillin 1 1.19356
PDGFB platelet-derived growth factor beta polypeptide 1.19267
FMOD fibromodulin 1.16826
MMP2 matrix metallopeptidase 2 1.1421
HEBP1 heme binding protein 1 1.12483
BGN biglycan 1.11863
CRCT1 cysteine-rich C-terminal 1 1.11774
C3P1 complement component 3 precursor pseudogene 1.10447
AMBN ameloblastin (enamel matrix protein) 1.10137
DCN decorin 1.08722
TNMD tenomodulin 1.0859
MMP13 matrix metallopeptidase 13 1.06912
NOTCH1 notch 1 1.04181
TIMP1 TIMP metallopeptidase inhibitor 1 1.02206
MMP8 matrix metallopeptidase 8 0.981518
GDF5 growth differentiation factor 5 0.973716
SPON1 spondin 1, extracellular matrix protein 0.963335
GDF7 growth differentiation factor 7 0.945226
IGF1 insulin-like growth factor 1 (somatomedin C) 0.927192
FGF7 fibroblast growth factor 7 0.899871
FBN2 fibrillin 2 0.895195
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.893921
ELN elastin 0.887133
POSTN periostin, osteoblast specific factor 0.887133
PTH parathyroid hormone 0.878243
MMP9 matrix metallopeptidase 9 0.870639
IL1A interleukin 1, alpha 0.862206
CALCA calcitonin-related polypeptide alpha 0.835737
IL6 interleukin 6 0.835318
S100A4 S100 calcium binding protein A4 0.835318
NANOG Nanog homeobox 0.806882
JUN jun proto-oncogene 0.803544
FGF1 fibroblast growth factor 1 (acidic) 0.793959
TIMP2 TIMP metallopeptidase inhibitor 2 0.775664
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 0.775664
MMP3 matrix metallopeptidase 3 0.774834
MAPK8 mitogen-activated protein kinase 8 0.764054
BMP4 bone morphogenetic protein 4 0.764054
BMP6 bone morphogenetic protein 6 0.762811
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.762397
MSX2 msh homeobox 2 0.762397
EPC2 enhancer of polycomb homolog 2 (Drosophila) 0.76157
DSPP dentin sialophosphoprotein 0.757432
AMTN amelotin 0.750405
TNF tumor necrosis factor 0.749579
CA9 carbonic anhydrase IX 0.745451
CD44 CD44 molecule (Indian blood group) 0.743389
CTGF connective tissue growth factor 0.740503
ITGA11 integrin, alpha 11 0.719524
ADAM28 ADAM metallopeptidase domain 28 0.714189
FBLN5 fibulin 5 0.703536
MANEAL mannosidase, endo-alpha-like 0.697399
CCL2 chemokine (C-C motif) ligand 2 0.691268
THY1 Thy-1 cell surface antigen 0.689226
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.688409
NOG noggin 0.685551
GIN1 gypsy retrotransposon integrase 1 0.681064
TAC1 tachykinin, precursor 1 0.680656
VCAN versican 0.678617
CTSK cathepsin K 0.668436
MFAP2 microfibrillar-associated protein 2 0.667622
CXCL8 chemokine (C-X-C motif) ligand 8 0.65746
NES nestin 0.657054
COL1A1 collagen, type I, alpha 1 0.656242
NGFR nerve growth factor receptor 0.646911
TNN tenascin N 0.646505
TLR2 toll-like receptor 2 0.635976
PCNA proliferating cell nuclear antigen 0.635572
SEBOX SEBOX homeobox 0.626273
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.614571
VEGFA vascular endothelial growth factor A 0.613764
FGFR2 fibroblast growth factor receptor 2 0.610943
RCL1 RNA terminal phosphate cyclase-like 1 0.604502
MGP matrix Gla protein 0.599273
LUM lumican 0.590839
EPRS glutamyl-prolyl-tRNA synthetase 0.575616
COL1A2 collagen, type I, alpha 2 0.574017
COL8A1 collagen, type VIII, alpha 1 0.569222
EDA ectodysplasin A 0.561644
SDC4 syndecan 4 0.557661
BMP3 bone morphogenetic protein 3 0.557661
PTH1R parathyroid hormone 1 receptor 0.556467
TNC tenascin C 0.547326
PTHLH parathyroid hormone-like hormone 0.546136
TERT telomerase reverse transcriptase 0.542963
SDC1 syndecan 1 0.54217
HMOX1 heme oxygenase 1 0.535042
TSPO translocator protein (18kDa) 0.521617
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.51453
LRRTM3 leucine rich repeat transmembrane neuronal 3 0.51335
CALB2 calbindin 2 0.505887
LGALS1 lectin, galactoside-binding, soluble, 1 0.504318
FOS FBJ murine osteosarcoma viral oncogene homolog 0.500007
UNC50 unc-50 homolog (C. elegans) 0.496092
GJA1 gap junction protein, alpha 1, 43kDa 0.481648
RPS27L ribosomal protein S27-like 0.476589
SOX9 SRY (sex determining region Y)-box 9 0.473092
TLR4 toll-like receptor 4 0.471151
MEPE matrix extracellular phosphoglycoprotein 0.469987
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.469211
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.469211
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.464174
TUFT1 tuftelin 1 0.460305
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.457214
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.456055
SCRG1 stimulator of chondrogenesis 1 0.455284
NOD1 nucleotide-binding oligomerization domain containing 1 0.454898
FLNB filamin B, beta 0.447576
SDC2 syndecan 2 0.441042
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 0.439123
CALB1 calbindin 1, 28kDa 0.436055
PELP1 proline, glutamate and leucine rich protein 1 0.433757
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.432991
JAG1 jagged 1 0.428783
ANXA5 annexin A5 0.426109
RPAIN RPA interacting protein 0.424581
NGF nerve growth factor (beta polypeptide) 0.424199
NELL1 NEL-like 1 (chicken) 0.423436
GAP43 growth associated protein 43 0.416957
HAS3 hyaluronan synthase 3 0.416576
BDNF brain-derived neurotrophic factor 0.413151
WNT3A wingless-type MMTV integration site family, member 3A 0.409731
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.409351
PLG plasminogen 0.406315
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 0.405555
HMGB1 high mobility group box 1 0.405176
PELI1 pellino E3 ubiquitin protein ligase 1 0.405176
CROT carnitine O-octanoyltransferase 0.40328
BCLAF1 BCL2-associated transcription factor 1 0.401386
FAT1 FAT atypical cadherin 1 0.401007
LRRTM1 leucine rich repeat transmembrane neuronal 1 0.388912
NPY neuropeptide Y 0.387027
CXCL12 chemokine (C-X-C motif) ligand 12 0.385143
KIF23 kinesin family member 23 0.384766
EMD emerin 0.38326
KCNK6 potassium channel, two pore domain subfamily K, member 6 0.38326
TDRD6 tudor domain containing 6 0.382508
HAS2 hyaluronan synthase 2 0.381379
IGFBP5 insulin-like growth factor binding protein 5 0.380627
SOX2 SRY (sex determining region Y)-box 2 0.377245
LDB2 LIM domain binding 2 0.377245
ESR2 estrogen receptor 2 (ER beta) 0.375368
SOST sclerostin 0.374618
LY86 lymphocyte antigen 86 0.370121
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 0.367502
FGFR1 fibroblast growth factor receptor 1 0.362646
RPS27 ribosomal protein S27 0.354084
CTRL chymotrypsin-like 0.352969
IL17RE interleukin 17 receptor E 0.352969
EGFR epidermal growth factor receptor 0.350743
CALCR calcitonin receptor 0.340019
BMP8A bone morphogenetic protein 8a 0.3356
STATH statherin 0.334865
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.331927
BEND5 BEN domain containing 5 0.331927
MSX1 msh homeobox 1 0.328994
IL17RD interleukin 17 receptor D 0.327164
KLF10 Kruppel-like factor 10 0.323509
SERTAD1 SERTA domain containing 1 0.320956
CRABP1 cellular retinoic acid binding protein 1 0.320591
CCL20 chemokine (C-C motif) ligand 20 0.317679
MPZ myelin protein zero 0.31332
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.312957
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 0.312232
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 0.310783
SEC14L2 SEC14-like 2 (S. cerevisiae) 0.310421
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.310059
EGFL6 EGF-like-domain, multiple 6 0.308974
CCL13 chemokine (C-C motif) ligand 13 0.307889
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.305001
VEGFB vascular endothelial growth factor B 0.303559
DOCK3 dedicator of cytokinesis 3 0.301398
ICAM1 intercellular adhesion molecule 1 0.298524
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.291008
MAB21L2 mab-21-like 2 (C. elegans) 0.286736
OGN osteoglycin 0.283899
DMP1 dentin matrix acidic phosphoprotein 1 0.283191
ASIC2 acid sensing (proton gated) ion channel 2 0.281776
ITPKA inositol-trisphosphate 3-kinase A 0.274394
CCL3 chemokine (C-C motif) ligand 3 0.271604
MAPK6 mitogen-activated protein kinase 6 0.269867
VCL vinculin 0.269867
NTF4 neurotrophin 4 0.259929
PRR4 proline rich 4 (lacrimal) 0.259591
IGF1R insulin-like growth factor 1 receptor 0.258243
DPF2 D4, zinc and double PHD fingers family 2 0.254239
KRT14 keratin 14, type I 0.253248
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 0.251279
RAB17 RAB17, member RAS oncogene family 0.251279
GRK1 G protein-coupled receptor kinase 1 0.250627
NOD2 nucleotide-binding oligomerization domain containing 2 0.248683
DNTT DNA nucleotidylexotransferase 0.24804
FGFR4 fibroblast growth factor receptor 4 0.245491
SFRP1 secreted frizzled-related protein 1 0.245175
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.244232
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.242672
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.240216
PLXNC1 plexin C1 0.240216
KRT8 keratin 8, type II 0.239913
PCDH9 protocadherin 9 0.239307
TBX1 T-box 1 0.239307
GDF2 growth differentiation factor 2 0.237513
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.235748
TICAM2 toll-like receptor adaptor molecule 2 0.235167
PLAU plasminogen activator, urokinase 0.235167
BAD BCL2-associated agonist of cell death 0.23459
ADIPOR1 adiponectin receptor 1 0.233731
IL17A interleukin 17A 0.230656
CD274 CD274 molecule 0.229839
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 0.228234
MMP11 matrix metallopeptidase 11 0.226926
PVALB parvalbumin 0.224893
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.221061
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.219928
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.219707
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 0.217974
TP53BP2 tumor protein p53 binding protein 2 0.217139
ASXL1 additional sex combs like transcriptional regulator 1 0.214576
CDNF cerebral dopamine neurotrophic factor 0.214202
SOX10 SRY (sex determining region Y)-box 10 0.21365
CCL5 chemokine (C-C motif) ligand 5 0.213291
CHD3 chromodomain helicase DNA binding protein 3 0.212761
FOSL1 FOS-like antigen 1 0.212761