peptide amidation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions. (Gene Ontology, GO_0001519)
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2 genes participating in the peptide amidation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
PAM peptidylglycine alpha-amidating monooxygenase
PGLYRP2 peptidoglycan recognition protein 2