pentose phosphate pathway Gene Set

Dataset KEGG Pathways
Category structural or functional annotations
Type pathway
Description The process in which glucose is oxidized, coupled to NADPH synthesis. Glucose 6-P is oxidized with the formation of carbon dioxide (CO2), ribulose 5-phosphate and reduced NADP; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses. (Gene Ontology, GO_0006098)
External Link http://www.genome.jp/kegg/pathway/hsa/hsa00030.html
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26 proteins participating in the pentose phosphate pathway pathway from the KEGG Pathways dataset.

Symbol Name
ALDOA aldolase A, fructose-bisphosphate
ALDOB aldolase B, fructose-bisphosphate
ALDOC aldolase C, fructose-bisphosphate
DERA deoxyribose-phosphate aldolase (putative)
FBP1 fructose-1,6-bisphosphatase 1
FBP2 fructose-1,6-bisphosphatase 2
G6PD glucose-6-phosphate dehydrogenase
GPI glucose-6-phosphate isomerase
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
PFKL phosphofructokinase, liver
PFKM phosphofructokinase, muscle
PFKP phosphofructokinase, platelet
PGD phosphogluconate dehydrogenase
PGLS 6-phosphogluconolactonase
PGM1 phosphoglucomutase 1
PGM3 phosphoglucomutase 3
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PRPS2 phosphoribosyl pyrophosphate synthetase 2
RBKS ribokinase
RPE ribulose-5-phosphate-3-epimerase
RPIA ribose 5-phosphate isomerase A
TALDO1 transaldolase 1
TKT transketolase
TKTL1 transketolase-like 1
TKTL2 transketolase-like 2