pentamidine-4573 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the pentamidine-4573 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADAM11 ADAM metallopeptidase domain 11
ADRA2B adrenoceptor alpha 2B
AFF1 AF4/FMR2 family, member 1
AFF4 AF4/FMR2 family, member 4
AHNAK AHNAK nucleoprotein
ARSB arylsulfatase B
ARTN artemin
BCL6 B-cell CLL/lymphoma 6
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1ORF116 chromosome 1 open reading frame 116
C2ORF27A chromosome 2 open reading frame 27A
C5ORF42 chromosome 5 open reading frame 42
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCKBR cholecystokinin B receptor
CD33 CD33 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CIZ1 CDKN1A interacting zinc finger protein 1
CNR2 cannabinoid receptor 2 (macrophage)
COL7A1 collagen, type VII, alpha 1
CREBZF CREB/ATF bZIP transcription factor
CSF1 colony stimulating factor 1 (macrophage)
CTSV cathepsin V
DMPK dystrophia myotonica-protein kinase
DNAAF1 dynein, axonemal, assembly factor 1
DPYS dihydropyrimidinase
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ESRRG estrogen-related receptor gamma
ETAA1 Ewing tumor-associated antigen 1
ETV6 ets variant 6
FAM63B family with sequence similarity 63, member B
FBXO41 F-box protein 41
FGF1 fibroblast growth factor 1 (acidic)
FHIT fragile histidine triad
FILIP1L filamin A interacting protein 1-like
FLJ22184
FLT1 fms-related tyrosine kinase 1
GK glycerol kinase
GK3P glycerol kinase 3 pseudogene
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HEATR6 HEAT repeat containing 6
HEMK1 HemK methyltransferase family member 1
HESX1 HESX homeobox 1
HMHB1 histocompatibility (minor) HB-1
ING2 inhibitor of growth family, member 2
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KLF12 Kruppel-like factor 12
LINC00115 long intergenic non-protein coding RNA 115
LOC100287387 uncharacterized LOC100287387
LY6G6C lymphocyte antigen 6 complex, locus G6C
MBNL3 muscleblind-like splicing regulator 3
MCC mutated in colorectal cancers
MEGF6 multiple EGF-like-domains 6
MFAP3 microfibrillar-associated protein 3
MRPL41 mitochondrial ribosomal protein L41
MST1 macrophage stimulating 1
MYO9B myosin IXB
N4BP2L2 NEDD4 binding protein 2-like 2
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPC1 Niemann-Pick disease, type C1
NPFF neuropeptide FF-amide peptide precursor
NRF1 nuclear respiratory factor 1
NRL neural retina leucine zipper
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAOX polyamine oxidase (exo-N4-amino)
PCDHB3 protocadherin beta 3
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
POFUT1 protein O-fucosyltransferase 1
POU6F2 POU class 6 homeobox 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRDX2 peroxiredoxin 2
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PVT1 Pvt1 oncogene (non-protein coding)
RAD23B RAD23 homolog B (S. cerevisiae)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
REEP2 receptor accessory protein 2
RFPL1S RFPL1 antisense RNA 1
RGS4 regulator of G-protein signaling 4
RS1 retinoschisin 1
SERHL2 serine hydrolase-like 2
SIRPA signal-regulatory protein alpha
SLC16A6 solute carrier family 16, member 6
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SOGA1 suppressor of glucose, autophagy associated 1
SOX15 SRY (sex determining region Y)-box 15
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TRIM2 tripartite motif containing 2
TRIM3 tripartite motif containing 3
TSNAXIP1 translin-associated factor X interacting protein 1
WSB1 WD repeat and SOCS box containing 1
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABHD17B abhydrolase domain containing 17B
ARHGAP10 Rho GTPase activating protein 10
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BMP15 bone morphogenetic protein 15
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF93 chromosome 14 open reading frame 93
C1QTNF1 C1q and tumor necrosis factor related protein 1
C7ORF43 chromosome 7 open reading frame 43
CENPJ centromere protein J
CES3 carboxylesterase 3
CFAP69 cilia and flagella associated protein 69
CIDEB cell death-inducing DFFA-like effector b
CLCA1 chloride channel accessory 1
CLCN5 chloride channel, voltage-sensitive 5
CORO1A coronin, actin binding protein, 1A
CPEB1 cytoplasmic polyadenylation element binding protein 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DSPP dentin sialophosphoprotein
DTX4 deltex 4, E3 ubiquitin ligase
EFNB1 ephrin-B1
ELOVL4 ELOVL fatty acid elongase 4
EN2 engrailed homeobox 2
FAM155A family with sequence similarity 155, member A
FAM186A family with sequence similarity 186, member A
FZD3 frizzled class receptor 3
GLB1L galactosidase, beta 1-like
GPR3 G protein-coupled receptor 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRAMD1C GRAM domain containing 1C
HECA headcase homolog (Drosophila)
HIST1H2AM histone cluster 1, H2am
HIST1H2BM histone cluster 1, H2bm
HYAL3 hyaluronoglucosaminidase 3
ICK intestinal cell (MAK-like) kinase
IFNA14 interferon, alpha 14
IL17RB interleukin 17 receptor B
ITK IL2-inducible T-cell kinase
KDM7A lysine (K)-specific demethylase 7A
KIAA1107 KIAA1107
LIME1 Lck interacting transmembrane adaptor 1
LINC00341 long intergenic non-protein coding RNA 341
LNPEP leucyl/cystinyl aminopeptidase
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LY6D lymphocyte antigen 6 complex, locus D
MAGEF1 melanoma antigen family F1
MED9 mediator complex subunit 9
MFSD6 major facilitator superfamily domain containing 6
MITF microphthalmia-associated transcription factor
MMRN2 multimerin 2
MT1M metallothionein 1M
MYO1F myosin IF
NPIPB3 nuclear pore complex interacting protein family, member B3
NXPH4 neurexophilin 4
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALMD palmdelphin
PCBP4 poly(rC) binding protein 4
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PID1 phosphotyrosine interaction domain containing 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLD2 phospholipase D2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLK2 polo-like kinase 2
POLH polymerase (DNA directed), eta
POM121 POM121 transmembrane nucleoporin
PROX1 prospero homeobox 1
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB36 RAB36, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RPH3AL rabphilin 3A-like (without C2 domains)
SAYSD1 SAYSVFN motif domain containing 1
SCD5 stearoyl-CoA desaturase 5
SCGB2A2 secretoglobin, family 2A, member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SNPH syntaphilin
TAOK1 TAO kinase 1
TOR4A torsin family 4, member A
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VN1R1 vomeronasal 1 receptor 1
ZNF10 zinc finger protein 10
ZNF137P zinc finger protein 137, pseudogene
ZNF205 zinc finger protein 205
ZNF214 zinc finger protein 214
ZNF343 zinc finger protein 343
ZNF37BP zinc finger protein 37B, pseudogene
ZNF415 zinc finger protein 415
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862