pcna complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex composed of three identical PCNA monomers, each comprising two similar domains, which are joined in a head-to-tail arrangement to form a homotrimer. Forms a ring-like structure in solution, with a central hole sufficiently large to accommodate the double helix of DNA. Originally characterized as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the replisome, and has also been shown to be involved in other processes including Okazaki fragment processing, DNA repair, translesion DNA synthesis, DNA methylation, chromatin remodeling and cell cycle regulation. (Gene Ontology, GO_0043626)
Similar Terms
Downloads & Tools

Genes

1 proteins localized to the pcna complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen 0.098109