papillary thyroid carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A thyroid carcinoma that is characterized by the small mushroom shape of the tumor which has a stem attached to the epithelial layer. (Human Disease Ontology, DOID_3969)
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Genes

282 genes co-occuring with the disease papillary thyroid carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TG thyroglobulin 2.4585
RET ret proto-oncogene 2.44083
PTCH1 patched 1 2.02794
LGALS3 lectin, galactoside-binding, soluble, 3 1.92811
KRT19 keratin 19, type I 1.59966
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 1.55646
PAX8 paired box 8 1.49657
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.42454
NKX2-1 NK2 homeobox 1 1.36684
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.29047
CCDC6 coiled-coil domain containing 6 1.25733
FOXE1 forkhead box E1 1.22995
ERC1 ELKS/RAB6-interacting/CAST family member 1 1.22215
TSHR thyroid stimulating hormone receptor 1.19532
TPCN1 two pore segment channel 1 1.17421
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 1.17292
CALCA calcitonin-related polypeptide alpha 1.11267
MIR221 microRNA 221 1.103
HRAS Harvey rat sarcoma viral oncogene homolog 1.10006
ZNF20 zinc finger protein 20 1.0033
ZNF121 zinc finger protein 121 1.0033
TP53 tumor protein p53 0.998236
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 0.977165
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.97086
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.97044
MET MET proto-oncogene, receptor tyrosine kinase 0.912257
TPO thyroid peroxidase 0.899514
NIM1K NIM1 serine/threonine protein kinase 0.889668
TFG TRK-fused gene 0.876557
OPTC opticin 0.876148
NT5C1B 5'-nucleotidase, cytosolic IB 0.874919
VEGFC vascular endothelial growth factor C 0.861818
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.86059
PDZRN4 PDZ domain containing ring finger 4 0.858543
TFF3 trefoil factor 3 (intestinal) 0.846669
CCDC67 coiled-coil domain containing 67 0.84544
SMIM19 small integral membrane protein 19 0.844621
DUSP6 dual specificity phosphatase 6 0.843392
MIR146A microRNA 146a 0.835198
CCND1 cyclin D1 0.832738
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 0.81059
PTEN phosphatase and tensin homolog 0.792951
C8ORF4 chromosome 8 open reading frame 4 0.788033
DOK6 docking protein 6 0.768801
MIR222 microRNA 222 0.750457
DOCK10 dedicator of cytokinesis 10 0.746798
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.743547
PTH parathyroid hormone 0.735433
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.698313
KRAS Kirsten rat sarcoma viral oncogene homolog 0.683493
NCOA4 nuclear receptor coactivator 4 0.677105
ZCCHC12 zinc finger, CCHC domain containing 12 0.675909
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.67551
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 0.668345
FER1L4 fer-1-like family member 4, pseudogene (functional) 0.666755
CSNK1G2 casein kinase 1, gamma 2 0.665166
HOOK3 hook microtubule-tethering protein 3 0.652484
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 0.646953
TRAK2 trafficking protein, kinesin binding 2 0.643009
GDNF glial cell derived neurotrophic factor 0.630027
SLITRK5 SLIT and NTRK-like family, member 5 0.629242
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.629242
NCAM1 neural cell adhesion molecule 1 0.623359
SFTPB surfactant protein B 0.622575
XKR4 XK, Kell blood group complex subunit-related family, member 4 0.619442
SNX5 sorting nexin 5 0.613574
DIO2 deiodinase, iodothyronine, type II 0.609666
PTCH2 patched 2 0.609666
ZNF135 zinc finger protein 135 0.60108
PPARG peroxisome proliferator-activated receptor gamma 0.59874
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.571884
SLA Src-like-adaptor 0.567997
HOOK2 hook microtubule-tethering protein 2 0.565277
GOLGA5 golgin A5 0.557509
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.555956
INTS5 integrator complex subunit 5 0.550522
SLITRK6 SLIT and NTRK-like family, member 6 0.546644
MPZL2 myelin protein zero-like 2 0.544705
LIMD2 LIM domain containing 2 0.542767
MT1G metallothionein 1G 0.536957
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.533475
WWTR1 WW domain containing transcription regulator 1 0.533475
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.533088
FLRT3 fibronectin leucine rich transmembrane protein 3 0.52343
FN1 fibronectin 1 0.523045
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 0.522659
KLF17 Kruppel-like factor 17 0.522273
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa 0.520731
NRTN neurturin 0.518805
DOK4 docking protein 4 0.518034
SCEL sciellin 0.51534
CAPZB capping protein (actin filament) muscle Z-line, beta 0.514956
QPCT glutaminyl-peptide cyclotransferase 0.513802
MLEC malectin 0.51188
CXCL14 chemokine (C-X-C motif) ligand 14 0.51188
DUSP5 dual specificity phosphatase 5 0.509959
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 0.507657
MEMO1 mediator of cell motility 1 0.506123
CLDN1 claudin 1 0.504973
TESC tescalcin 0.504207
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.500761
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.498849
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.496939
FRMD6 FERM domain containing 6 0.496175
MUC1 mucin 1, cell surface associated 0.496175
NDRG3 NDRG family member 3 0.493885
SORBS2 sorbin and SH3 domain containing 2 0.487407
TXNRD2 thioredoxin reductase 2 0.487027
MCM3 minichromosome maintenance complex component 3 0.484364
CD44 CD44 molecule (Indian blood group) 0.482844
PGPEP1 pyroglutamyl-peptidase I 0.47753
PCNA proliferating cell nuclear antigen 0.470711
LGALS8 lectin, galactoside-binding, soluble, 8 0.468063
NPNT nephronectin 0.465416
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.465038
NELL2 NEL-like 2 (chicken) 0.454847
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.453716
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 0.449947
PTPRJ protein tyrosine phosphatase, receptor type, J 0.446558
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.446182
WDR1 WD repeat domain 1 0.442418
S100A6 S100 calcium binding protein A6 0.440538
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 0.434899
NINJ1 ninjurin 1 0.434899
AKAP9 A kinase (PRKA) anchor protein 9 0.427015
CXCL12 chemokine (C-X-C motif) ligand 12 0.42139
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.42139
CRABP1 cellular retinoic acid binding protein 1 0.419517
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.415398
MUC15 mucin 15, cell surface associated 0.410161
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.407545
TIMP1 TIMP metallopeptidase inhibitor 1 0.407545
ZNHIT2 zinc finger, HIT-type containing 2 0.402318
STRN striatin, calmodulin binding protein 0.399707
PDPK1 3-phosphoinositide dependent protein kinase 1 0.394863
TMSB10 thymosin beta 10 0.392257
ZNF197 zinc finger protein 197 0.391513
ACSBG1 acyl-CoA synthetase bubblegum family member 1 0.390769
LCMT2 leucine carboxyl methyltransferase 2 0.389281
MMP9 matrix metallopeptidase 9 0.383337
ECM1 extracellular matrix protein 1 0.382594
S100A11 S100 calcium binding protein A11 0.378885
ESR1 estrogen receptor 1 0.378143
CLDN7 claudin 7 0.375179
PDPN podoplanin 0.374809
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 0.374809
GBP2 guanylate binding protein 2, interferon-inducible 0.371847
PRRX1 paired related homeobox 1 0.368888
HIPK3 homeodomain interacting protein kinase 3 0.368149
VEGFA vascular endothelial growth factor A 0.364824
DNPEP aspartyl aminopeptidase 0.359657
PDLIM3 PDZ and LIM domain 3 0.359289
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 0.357814
KIF23 kinesin family member 23 0.351555
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.348246
MMP11 matrix metallopeptidase 11 0.344574
THRB thyroid hormone receptor, beta 0.34384
ATM ATM serine/threonine kinase 0.34384
FLT4 fms-related tyrosine kinase 4 0.339806
FGF13 fibroblast growth factor 13 0.339806
APOC1 apolipoprotein C-I 0.337242
ADAT2 adenosine deaminase, tRNA-specific 2 0.332487
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.331756
SNAI1 snail family zinc finger 1 0.331391
SMAD4 SMAD family member 4 0.329565
ZMYM3 zinc finger, MYM-type 3 0.327375
KTN1 kinectin 1 (kinesin receptor) 0.326281
KRT7 keratin 7, type II 0.321181
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.319363
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.313189
PRKCE protein kinase C, epsilon 0.310652
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.309204
USP22 ubiquitin specific peptidase 22 0.309204
ZHX2 zinc fingers and homeoboxes 2 0.30848
HOXB9 homeobox B9 0.307757
PIWIL2 piwi-like RNA-mediated gene silencing 2 0.306672
MMP2 matrix metallopeptidase 2 0.305587
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.305587
PTPRU protein tyrosine phosphatase, receptor type, U 0.304503
RPIA ribose 5-phosphate isomerase A 0.30342
SEPT7 septin 7 0.300533
MAPK3 mitogen-activated protein kinase 3 0.300533
LYPD1 LY6/PLAUR domain containing 1 0.299092
SST somatostatin 0.298371
NAPSA napsin A aspartic peptidase 0.291539
PSPN persephin 0.29118
CDX2 caudal type homeobox 2 0.288668
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.285444
CAPN5 calpain 5 0.283655
DUOXA2 dual oxidase maturation factor 2 0.283297
MRC2 mannose receptor, C type 2 0.279011
GDF15 growth differentiation factor 15 0.278297
PDLIM5 PDZ and LIM domain 5 0.27794
NLN neurolysin (metallopeptidase M3 family) 0.27794
TRIM58 tripartite motif containing 58 0.276514
CXCR4 chemokine (C-X-C motif) receptor 4 0.275089
CAV2 caveolin 2 0.274732
EPHB4 EPH receptor B4 0.274376
EPS8 epidermal growth factor receptor pathway substrate 8 0.274376
CA12 carbonic anhydrase XII 0.269043
MT1X metallothionein 1X 0.267267
IL1RAP interleukin 1 receptor accessory protein 0.266913
NDRG4 NDRG family member 4 0.263722
CLDN10 claudin 10 0.261245
ITCH itchy E3 ubiquitin protein ligase 0.260891
HOXB5 homeobox B5 0.260891
GNAS GNAS complex locus 0.25983
RAB2A RAB2A, member RAS oncogene family 0.257711
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.256299
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.255946
CDKN2A cyclin-dependent kinase inhibitor 2A 0.251718
CD68 CD68 molecule 0.251366
TSPO translocator protein (18kDa) 0.24996
PTPRC protein tyrosine phosphatase, receptor type, C 0.247852
EGFR epidermal growth factor receptor 0.247501
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.245747
CKS2 CDC28 protein kinase regulatory subunit 2 0.245396
MARK2 MAP/microtubule affinity-regulating kinase 2 0.244696
CREB3L2 cAMP responsive element binding protein 3-like 2 0.243645
CREB1 cAMP responsive element binding protein 1 0.242945
STPG1 sperm-tail PG-rich repeat containing 1 0.242245
S100A4 S100 calcium binding protein A4 0.240847
RAB23 RAB23, member RAS oncogene family 0.239101
PDE9A phosphodiesterase 9A 0.238752
MIR31 microRNA 31 0.23666
PRDX2 peroxiredoxin 2 0.234225
HLA-G major histocompatibility complex, class I, G 0.232142
KRT1 keratin 1, type II 0.232142
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.230755
PTTG1 pituitary tumor-transforming 1 0.227988
UNC5C unc-5 homolog C (C. elegans) 0.226607
DIO3 deiodinase, iodothyronine, type III 0.226607
TRIP10 thyroid hormone receptor interactor 10 0.225573
RIPK3 receptor-interacting serine-threonine kinase 3 0.224196
C11ORF30 chromosome 11 open reading frame 30 0.222822
RXRB retinoid X receptor, beta 0.222136
PDZD4 PDZ domain containing 4 0.22145
STIP1 stress-induced phosphoprotein 1 0.219057
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.218374
TPM3 tropomyosin 3 0.215992
LDB1 LIM domain binding 1 0.213283
CAV1 caveolin 1, caveolae protein, 22kDa 0.212945
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.207912
MIR130B microRNA 130b 0.20658
GAGE1 G antigen 1 0.205585
PLAU plasminogen activator, urokinase 0.199681
MEN1 multiple endocrine neoplasia I 0.19742
CDC7 cell division cycle 7 0.196139
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.195501
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.193285
TKTL1 transketolase-like 1 0.192971
BSG basigin (Ok blood group) 0.190168
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.188632
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.188326
MPPED2 metallophosphoesterase domain containing 2 0.18621
SPP1 secreted phosphoprotein 1 0.18621
NDRG1 N-myc downstream regulated 1 0.183835
DUOXA1 dual oxidase maturation factor 1 0.183248
BMPR1B bone morphogenetic protein receptor, type IB 0.182957
PEBP1 phosphatidylethanolamine binding protein 1 0.181798
MED1 mediator complex subunit 1 0.18151
ENO2 enolase 2 (gamma, neuronal) 0.180367
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.176215
AFM afamin 0.174093
TENM1 teneurin transmembrane protein 1 0.174093
FAP fibroblast activation protein, alpha 0.174093
DIO1 deiodinase, iodothyronine, type I 0.170054
GAGE12I G antigen 12I 0.169812
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.168617
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 0.168381
EMD emerin 0.167682
DDIT3 DNA-damage-inducible transcript 3 0.166319
PTER phosphotriesterase related 0.165001
ARAF A-Raf proto-oncogene, serine/threonine kinase 0.165001
OGFR opioid growth factor receptor 0.163938
PDCD5 programmed cell death 5 0.163523
TERT telomerase reverse transcriptase 0.162707
SLC26A4 solute carrier family 26 (anion exchanger), member 4 0.162505
AXIN1 axin 1 0.161523
EPHA5 EPH receptor A5 0.161139
ULBP2 UL16 binding protein 2 0.160948
FBXO9 F-box protein 9 0.158266