pancreatic islet Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Irregular microscopic structures scattered throughout the pancreas and comprising its endocrine part (the endocrine pancreas). In humans, they are composed of at least four types of cells: the alpha cells, which secrete glucagon; the beta cells, which are the most abundant and secrete insulin; the delta cells, which secrete somatostatin; and the PP cells, which secrete pancreatic polypeptide. Degeneration of the beta cells, whose secretion (insulin) is important in carbohydrate metabolism, is the major cause of type I diabetes mellitus. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000991)
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Genes

963 proteins co-occuring with the tissue pancreatic islet in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
INS insulin 5.0328
GCG glucagon 3.75611
IAPP islet amyloid polypeptide 3.09808
GCK glucokinase (hexokinase 4) 3.01864
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 2.83835
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.73528
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 2.68769
FOXM1 forkhead box M1 2.54026
SST somatostatin 2.52166
GIP gastric inhibitory polypeptide 2.43484
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 2.399
PPY pancreatic polypeptide 2.27667
PDX1 pancreatic and duodenal homeobox 1 2.24535
DPP4 dipeptidyl-peptidase 4 2.22143
PAX4 paired box 4 2.21298
HMX1 H6 family homeobox 1 2.19506
NEUROG3 neurogenin 3 2.16391
GLP1R glucagon-like peptide 1 receptor 2.12938
IRS2 insulin receptor substrate 2 2.07868
NIT1 nitrilase 1 2.07066
LAD1 ladinin 1 2.03909
NEUROD1 neuronal differentiation 1 2.01078
HNF1A HNF1 homeobox A 2.00865
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.99215
INSR insulin receptor 1.96778
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.95566
IL1B interleukin 1, beta 1.92632
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.9107
PTPRN protein tyrosine phosphatase, receptor type, N 1.86255
FFAR1 free fatty acid receptor 1 1.85327
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 1.81532
LEP leptin 1.77329
G6PC2 glucose-6-phosphatase, catalytic, 2 1.76375
TCF7 transcription factor 7 (T-cell specific, HMG-box) 1.74176
NKX2-2 NK2 homeobox 2 1.72235
MEN1 multiple endocrine neoplasia I 1.71291
CD4 CD4 molecule 1.66957
BTC betacellulin 1.65207
HK1 hexokinase 1 1.63456
IRS1 insulin receptor substrate 1 1.63306
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.62707
GIPR gastric inhibitory polypeptide receptor 1.61858
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.61211
ISL1 ISL LIM homeobox 1 1.57601
WFS1 Wolfram syndrome 1 (wolframin) 1.56671
HNF4A hepatocyte nuclear factor 4, alpha 1.53958
HNF1B HNF1 homeobox B 1.51902
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.5119
NKX6-1 NK6 homeobox 1 1.50764
GCGR glucagon receptor 1.49914
SYTL4 synaptotagmin-like 4 1.48036
FOXA2 forkhead box A2 1.47055
GAST gastrin 1.45983
CAPN10 calpain 10 1.45518
GJD2 gap junction protein, delta 2, 36kDa 1.44218
IGF1 insulin-like growth factor 1 (somatomedin C) 1.43431
INSM2 insulinoma-associated 2 1.41999
PAX6 paired box 6 1.41814
PTPN3 protein tyrosine phosphatase, non-receptor type 3 1.41768
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 1.38459
GCKR glucokinase (hexokinase 4) regulator 1.38276
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 1.38184
FOXO1 forkhead box O1 1.38047
CHGA chromogranin A 1.37956
GHRL ghrelin/obestatin prepropeptide 1.3759
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.36541
PC pyruvate carboxylase 1.35767
PPARG peroxisome proliferator-activated receptor gamma 1.35631
HHEX hematopoietically expressed homeobox 1.335
STX1A syntaxin 1A (brain) 1.31198
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.28995
FAM3B family with sequence similarity 3, member B 1.28592
GPR119 G protein-coupled receptor 119 1.2671
TNF tumor necrosis factor 1.26531
SOD2 superoxide dismutase 2, mitochondrial 1.26263
MTNR1B melatonin receptor 1B 1.25592
PCSK1 proprotein convertase subtilisin/kexin type 1 1.25145
MNX1 motor neuron and pancreas homeobox 1 1.24744
NSF N-ethylmaleimide-sensitive factor 1.24119
GLIS3 GLIS family zinc finger 3 1.23361
LEPR leptin receptor 1.2198
CCK cholecystokinin 1.21624
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.21179
CPE carboxypeptidase E 1.20378
TRAC T cell receptor alpha constant 1.19489
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 1.19445
PTPRD protein tyrosine phosphatase, receptor type, D 1.194
PTPN12 protein tyrosine phosphatase, non-receptor type 12 1.19178
PCSK2 proprotein convertase subtilisin/kexin type 2 1.18779
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 1.18468
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 1.18468
PYY peptide YY 1.17891
G6PC glucose-6-phosphatase, catalytic subunit 1.16959
TXNIP thioredoxin interacting protein 1.16826
DNAH8 dynein, axonemal, heavy chain 8 1.16338
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.16249
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.16205
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.16072
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.15628
ADCY2 adenylate cyclase 2 (brain) 1.14919
FASLG Fas ligand (TNF superfamily, member 6) 1.14387
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.14343
DDIT3 DNA-damage-inducible transcript 3 1.14033
PKLR pyruvate kinase, liver and RBC 1.13102
HLA-B major histocompatibility complex, class I, B 1.13014
VPREB1 pre-B lymphocyte 1 1.12881
RAB3A RAB3A, member RAS oncogene family 1.12615
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.12394
ICA1 islet cell autoantigen 1, 69kDa 1.11951
SLC30A10 solute carrier family 30, member 10 1.11818
CAT catalase 1.11331
SYT7 synaptotagmin VII 1.1111
RAB27A RAB27A, member RAS oncogene family 1.10756
RETN resistin 1.10624
JUN jun proto-oncogene 1.10535
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.10402
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.09474
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 1.06912
TMEM27 transmembrane protein 27 1.06691
CALCA calcitonin-related polypeptide alpha 1.06162
STXBP1 syntaxin binding protein 1 1.05985
PKM pyruvate kinase, muscle 1.05633
NNT nicotinamide nucleotide transhydrogenase 1.05369
PPARA peroxisome proliferator-activated receptor alpha 1.04445
NES nestin 1.02688
KRT19 keratin 19, type I 1.026
GAL galanin/GMAP prepropeptide 1.02513
FOXP3 forkhead box P3 1.02381
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.02381
HLA-C major histocompatibility complex, class I, C 1.01549
PFKM phosphofructokinase, muscle 1.01506
ALB albumin 1.01069
GPX1 glutathione peroxidase 1 1.0085
PLA2G1B phospholipase A2, group IB (pancreas) 1.00589
CCND2 cyclin D2 0.998037
XBP1 X-box binding protein 1 0.994119
CDC123 cell division cycle 123 0.993684
FFAR4 free fatty acid receptor 4 0.991074
PASK PAS domain containing serine/threonine kinase 0.990639
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.988466
PTF1A pancreas specific transcription factor, 1a 0.983688
SREBF1 sterol regulatory element binding transcription factor 1 0.980651
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.980217
PDE3B phosphodiesterase 3B, cGMP-inhibited 0.971552
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.968955
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.967657
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.962903
IGF2 insulin-like growth factor 2 0.962903
ENSA endosulfine alpha 0.961607
MAPK8 mitogen-activated protein kinase 8 0.959449
ATF6 activating transcription factor 6 0.959017
GPX5 glutathione peroxidase 5 0.955996
C2CD4B C2 calcium-dependent domain containing 4B 0.952547
GPX4 glutathione peroxidase 4 0.951685
MLXIPL MLX interacting protein-like 0.951685
NPY neuropeptide Y 0.947378
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.946517
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.945656
CSH2 chorionic somatomammotropin hormone 2 0.944796
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.944366
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.934054
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 0.934054
PRF1 perforin 1 (pore forming protein) 0.933624
ERN1 endoplasmic reticulum to nucleus signaling 1 0.929335
PRL prolactin 0.921199
CHD4 chromodomain helicase DNA binding protein 4 0.920344
ATF4 activating transcription factor 4 0.909666
GRP gastrin-releasing peptide 0.908814
POMC proopiomelanocortin 0.908814
THADA thyroid adenoma associated 0.907961
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.90285
NAMPT nicotinamide phosphoribosyltransferase 0.901147
RPH3A rabphilin 3A 0.901147
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.899871
SCG5 secretogranin V 0.888829
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.883744
JAZF1 JAZF zinc finger 1 0.875706
NOS2 nitric oxide synthase 2, inducible 0.875284
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.875284
UNC13A unc-13 homolog A (C. elegans) 0.865999
TSPAN8 tetraspanin 8 0.86347
CXCL10 chemokine (C-X-C motif) ligand 10 0.857995
BTBD10 BTB (POZ) domain containing 10 0.853368
SYT3 synaptotagmin III 0.852527
SNAP23 synaptosomal-associated protein, 23kDa 0.847484
STX4 syntaxin 4 0.844965
CREB1 cAMP responsive element binding protein 1 0.836575
JAK2 Janus kinase 2 0.836575
FTO fat mass and obesity associated 0.836156
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.834899
SHB Src homology 2 domain containing adaptor protein B 0.83448
LIPE lipase, hormone-sensitive 0.828197
FURIN furin (paired basic amino acid cleaving enzyme) 0.827778
BAX BCL2-associated X protein 0.827778
GLUD1 glutamate dehydrogenase 1 0.825268
TMED6 transmembrane emp24 protein transport domain containing 6 0.821085
SOX17 SRY (sex determining region Y)-box 17 0.818158
CHGB chromogranin B 0.816904
STK39 serine threonine kinase 39 0.81565
TGFB1 transforming growth factor, beta 1 0.807716
IL1RN interleukin 1 receptor antagonist 0.801042
SSTR5 somatostatin receptor 5 0.800626
STAP2 signal transducing adaptor family member 2 0.799375
REG1A regenerating islet-derived 1 alpha 0.79146
SSTR1 somatostatin receptor 1 0.788131
PARP1 poly (ADP-ribose) polymerase 1 0.78522
FFAR2 free fatty acid receptor 2 0.784804
CD38 CD38 molecule 0.784388
PTH parathyroid hormone 0.783972
STAT1 signal transducer and activator of transcription 1, 91kDa 0.783141
EXOC3L1 exocyst complex component 3-like 1 0.77774
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.774834
HBA2 hemoglobin, alpha 2 0.768197
CDK4 cyclin-dependent kinase 4 0.767783
CHCHD2P9 coiled-coil-helix-coiled-coil-helix domain containing 2 pseudogene 9 0.767783
SOX13 SRY (sex determining region Y)-box 13 0.760328
SSTR2 somatostatin receptor 2 0.759086
DNTT DNA nucleotidylexotransferase 0.744214
SYT8 synaptotagmin VIII 0.744214
PPP4C protein phosphatase 4, catalytic subunit 0.744214
SOCS1 suppressor of cytokine signaling 1 0.742152
NPS neuropeptide S 0.741327
KCTD20 potassium channel tetramerization domain containing 20 0.740915
SIRT1 sirtuin 1 0.739266
REG3A regenerating islet-derived 3 alpha 0.737206
TRH thyrotropin-releasing hormone 0.735971
RIMS2 regulating synaptic membrane exocytosis 2 0.735147
SCGN secretagogin, EF-hand calcium binding protein 0.73062
SUMO4 small ubiquitin-like modifier 4 0.724863
HBA1 hemoglobin, alpha 1 0.724453
CORO1C coronin, actin binding protein, 1C 0.722809
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.721577
CRP C-reactive protein, pentraxin-related 0.718292
GLB1 galactosidase, beta 1 0.71501
BCL2L1 BCL2-like 1 0.712959
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.7105
NLRP10 NLR family, pyrin domain containing 10 0.7105
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 0.70845
SYP synaptophysin 0.702717
CDX2 caudal type homeobox 2 0.699853
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.698216
NGF nerve growth factor (beta polypeptide) 0.698216
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.696581
SYT9 synaptotagmin IX 0.694946
VEGFA vascular endothelial growth factor A 0.694537
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.692493
IL2 interleukin 2 0.687184
IL6 interleukin 6 0.683919
DOC2B double C2-like domains, beta 0.683103
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.67658
STYX serine/threonine/tyrosine interacting protein 0.675357
RBP4 retinol binding protein 4, plasma 0.67495
IL4 interleukin 4 0.672506
ACLY ATP citrate lyase 0.672506
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.671285
VIP vasoactive intestinal peptide 0.66925
IGFBP1 insulin-like growth factor binding protein 1 0.66925
CELA1 chymotrypsin-like elastase family, member 1 0.665182
ICAM1 intercellular adhesion molecule 1 0.663149
RFX6 regulatory factor X, 6 0.658678
INSRR insulin receptor-related receptor 0.654618
IL10 interleukin 10 0.652589
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.648938
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.6461
CCL2 chemokine (C-C motif) ligand 2 0.644479
ACVR1C activin A receptor, type IC 0.643669
FRK fyn-related Src family tyrosine kinase 0.642858
STC1 stanniocalcin 1 0.638404
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.638404
MGAM maltase-glucoamylase 0.632335
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.62991
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.628293
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.627485
ALX3 ALX homeobox 3 0.627081
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.625465
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.621831
IER3IP1 immediate early response 3 interacting protein 1 0.621831
TFCP2 transcription factor CP2 0.6182
HYOU1 hypoxia up-regulated 1 0.614571
ANXA5 annexin A5 0.612152
PCIF1 PDX1 C-terminal inhibiting factor 1 0.612152
ADRA2A adrenoceptor alpha 2A 0.610541
ONECUT1 one cut homeobox 1 0.608124
MRPS31 mitochondrial ribosomal protein S31 0.607722
SOX4 SRY (sex determining region Y)-box 4 0.606112
EXTL3 exostosin-like glycosyltransferase 3 0.605306
SCG2 secretogranin II 0.602892
IFNA1 interferon, alpha 1 0.602892
GHSR growth hormone secretagogue receptor 0.602088
DUSP9 dual specificity phosphatase 9 0.600479
IRF1 interferon regulatory factor 1 0.600077
LGALS4 lectin, galactoside-binding, soluble, 4 0.596862
CCDC116 coiled-coil domain containing 116 0.59646
HADH hydroxyacyl-CoA dehydrogenase 0.59124
NTS neurotensin 0.589234
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 0.586828
POU3F4 POU class 3 homeobox 4 0.584823
SNAPIN SNAP-associated protein 0.584422
SOCS3 suppressor of cytokine signaling 3 0.584422
GHRH growth hormone releasing hormone 0.584022
ACTB actin, beta 0.58282
MMD monocyte to macrophage differentiation-associated 0.58242
CPA6 carboxypeptidase A6 0.582019
IL2RA interleukin 2 receptor, alpha 0.576015
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 0.575616
GK3P glycerol kinase 3 pseudogene 0.575216
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.574816
CCND1 cyclin D1 0.574816
CCNI2 cyclin I family, member 2 0.574816
NUPR1 nuclear protein, transcriptional regulator, 1 0.574816
CPB1 carboxypeptidase B1 (tissue) 0.574416
CD40LG CD40 ligand 0.572418
SIRT4 sirtuin 4 0.572418
IGF1R insulin-like growth factor 1 receptor 0.57082
ZDHHC23 zinc finger, DHHC-type containing 23 0.569622
ZBED3 zinc finger, BED-type containing 3 0.568823
STXBP3 syntaxin binding protein 3 0.568025
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.567227
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.564833
ACTG1 actin gamma 1 0.563637
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.562441
TRIB3 tribbles pseudokinase 3 0.556467
GK glycerol kinase 0.556467
HLA-E major histocompatibility complex, class I, E 0.554478
HMOX1 heme oxygenase 1 0.554478
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.55408
HLA-A major histocompatibility complex, class I, A 0.55249
ARNT aryl hydrocarbon receptor nuclear translocator 0.552093
PTBP1 polypyrimidine tract binding protein 1 0.551695
ADAM30 ADAM metallopeptidase domain 30 0.551298
CNOT2 CCR4-NOT transcription complex, subunit 2 0.550503
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.549709
CREM cAMP responsive element modulator 0.54812
CLCN3 chloride channel, voltage-sensitive 3 0.547724
USF1 upstream transcription factor 1 0.546136
AGMO alkylglycerol monooxygenase 0.540585
DLX3 distal-less homeobox 3 0.539
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.538604
CD276 CD276 molecule 0.538209
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.536625
FABP2 fatty acid binding protein 2, intestinal 0.536229
GPER1 G protein-coupled estrogen receptor 1 0.531089
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.529903
MAPK11 mitogen-activated protein kinase 11 0.528719
PTPMT1 protein tyrosine phosphatase, mitochondrial 1 0.527928
FOXP2 forkhead box P2 0.527928
FHDC1 FH2 domain containing 1 0.527928
NLRP2 NLR family, pyrin domain containing 2 0.527139
IFIH1 interferon induced with helicase C domain 1 0.525166
FXN frataxin 0.525166
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.524377
HSPA4 heat shock 70kDa protein 4 0.518072
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.515317
RBBP5 retinoblastoma binding protein 5 0.514924
VAMP3 vesicle-associated membrane protein 3 0.51453
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.51453
SYT1 synaptotagmin I 0.511778
TG thyroglobulin 0.511384
GPR39 G protein-coupled receptor 39 0.507849
KLF11 Kruppel-like factor 11 0.507457
CD40 CD40 molecule, TNF receptor superfamily member 5 0.506672
TRPM3 transient receptor potential cation channel, subfamily M, member 3 0.504318
PPY2P pancreatic polypeptide 2, pseudogene 0.501574
IGFBP3 insulin-like growth factor binding protein 3 0.500007
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 0.499223
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.499223
AIRE autoimmune regulator 0.495701
CASR calcium-sensing receptor 0.495309
DDTL D-dopachrome tautomerase-like 0.495309
SNX19 sorting nexin 19 0.494918
C2CD4A C2 calcium-dependent domain containing 4A 0.490229
IL1A interleukin 1, alpha 0.489057
ADIPOR1 adiponectin receptor 1 0.489057
ADM adrenomedullin 0.488667
CSN1S1 casein alpha s1 0.488276
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.488276
LTA lymphotoxin alpha 0.486716
PCNA proliferating cell nuclear antigen 0.486326
ACE angiotensin I converting enzyme 0.484766
DLK1 delta-like 1 homolog (Drosophila) 0.484766
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.483986
ILDR2 immunoglobulin-like domain containing receptor 2 0.482428
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.481648
IDE insulin-degrading enzyme 0.480091
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.479312
DMBT1 deleted in malignant brain tumors 1 0.476589
FAM3D family with sequence similarity 3, member D 0.475423
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.47348
ENO2 enolase 2 (gamma, neuronal) 0.470763
FASN fatty acid synthase 0.470375
KIF12 kinesin family member 12 0.469987
CDC42 cell division cycle 42 0.468048
RPS6 ribosomal protein S6 0.464948
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.461852
PTEN phosphatase and tensin homolog 0.460305
PYGM phosphorylase, glycogen, muscle 0.460305
TRPM5 transient receptor potential cation channel, subfamily M, member 5 0.458373
H3F3A H3 histone, family 3A 0.457214
EXT2 exostosin glycosyltransferase 2 0.457214
H3F3B H3 histone, family 3B (H3.3B) 0.457214
CELA3B chymotrypsin-like elastase family, member 3B 0.45567
CA2 carbonic anhydrase II 0.455284
HK2 hexokinase 2 0.454898
MLYCD malonyl-CoA decarboxylase 0.454512
ATF3 activating transcription factor 3 0.453355
ADRB3 adrenoceptor beta 3 0.452584
LDHA lactate dehydrogenase A 0.449886
FAM111A family with sequence similarity 111, member A 0.447576
ADIPOR2 adiponectin receptor 2 0.443731
COG2 component of oligomeric golgi complex 2 0.442578
SOX9 SRY (sex determining region Y)-box 9 0.44181
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.441042
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.43989
TLR4 toll-like receptor 4 0.437205
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.436438
CISH cytokine inducible SH2-containing protein 0.435672
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.435289
ATG7 autophagy related 7 0.433757
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 0.433757
FOXA1 forkhead box A1 0.432991
FAM3A family with sequence similarity 3, member A 0.432225
PTPN2 protein tyrosine phosphatase, non-receptor type 2 0.432225
REST RE1-silencing transcription factor 0.431077
TXN thioredoxin 0.428783
TCF3 transcription factor 3 0.426109
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.424581
USF2 upstream transcription factor 2, c-fos interacting 0.422292
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 0.42191
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 0.420004
SHBG sex hormone-binding globulin 0.41848
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 0.41848
TICAM2 toll-like receptor adaptor molecule 2 0.417337
UCN3 urocortin 3 0.416957
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.416195
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.415434
GSK3B glycogen synthase kinase 3 beta 0.414293
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 0.413151
UNC13B unc-13 homolog B (C. elegans) 0.41087
MBOAT4 membrane bound O-acyltransferase domain containing 4 0.409731
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.408972
C21ORF2 chromosome 21 open reading frame 2 0.407832
INSM1 insulinoma-associated 1 0.406315
DGKB diacylglycerol kinase, beta 90kDa 0.406315
CNR1 cannabinoid receptor 1 (brain) 0.405555
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.405176
GIMAP5 GTPase, IMAP family member 5 0.404797
FFAR3 free fatty acid receptor 3 0.404797
ERI1 exoribonuclease 1 0.404039
NNAT neuronatin 0.404039
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.404039
RYR1 ryanodine receptor 1 (skeletal) 0.402901
TSC2 tuberous sclerosis 2 0.401386
PFKL phosphofructokinase, liver 0.399114
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.396465
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.396087
SLC30A5 solute carrier family 30 (zinc transporter), member 5 0.395709
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 0.395331
TNS1 tensin 1 0.395331
TPO thyroid peroxidase 0.394953
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.393819
GUCY2C guanylate cyclase 2C 0.393064
BRS3 bombesin-like receptor 3 0.392309
CXCR3 chemokine (C-X-C motif) receptor 3 0.391931
CDK5 cyclin-dependent kinase 5 0.391553
NPR1 natriuretic peptide receptor 1 0.391176
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.391176
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.391176
SSTR3 somatostatin receptor 3 0.389289
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 0.389289
DPT dermatopontin 0.388912
RAD52 RAD52 homolog (S. cerevisiae) 0.388535
PRDX4 peroxiredoxin 4 0.387404
FOS FBJ murine osteosarcoma viral oncogene homolog 0.387404
THY1 Thy-1 cell surface antigen 0.38552
FBP1 fructose-1,6-bisphosphatase 1 0.38439
HRK harakiri, BCL2 interacting protein 0.383637
G6PD glucose-6-phosphate dehydrogenase 0.382131
FGF1 fibroblast growth factor 1 (acidic) 0.382131
PBX1 pre-B-cell leukemia homeobox 1 0.382131
ZFAND6 zinc finger, AN1-type domain 6 0.381379
COQ6 coenzyme Q6 monooxygenase 0.379499
ARX aristaless related homeobox 0.379123
STXBP5L syntaxin binding protein 5-like 0.378372
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.377996
TLR2 toll-like receptor 2 0.377245
AEBP2 AE binding protein 2 0.376119
TF transferrin 0.374993
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.374243
PYGB phosphorylase, glycogen; brain 0.371245
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 0.369373
AFF2 AF4/FMR2 family, member 2 0.368998
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.367502
PPP5C protein phosphatase 5, catalytic subunit 0.366754
LRP11 low density lipoprotein receptor-related protein 11 0.36526
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.363393
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.363393
HMGN3 high mobility group nucleosomal binding domain 3 0.361527
B2M beta-2-microglobulin 0.361155
PTS 6-pyruvoyltetrahydropterin synthase 0.360409
MLN motilin 0.359664
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.359292
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.359292
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.35743
BBS2 Bardet-Biedl syndrome 2 0.357058
MICA MHC class I polypeptide-related sequence A 0.356314
KRT20 keratin 20, type I 0.352598
ESR1 estrogen receptor 1 0.352227
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.350001
SYT5 synaptotagmin V 0.34926
CSN3 casein kappa 0.348519
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.347408
DLL1 delta-like 1 (Drosophila) 0.346668
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.346298
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.345188
IRS4 insulin receptor substrate 4 0.344449
FTH1 ferritin, heavy polypeptide 1 0.344449
PYGL phosphorylase, glycogen, liver 0.344079
MAPK3 mitogen-activated protein kinase 3 0.34371
FST follistatin 0.34334
NIT2 nitrilase family, member 2 0.341863
PRKD1 protein kinase D1 0.340388
PPARD peroxisome proliferator-activated receptor delta 0.340019
KIF27 kinesin family member 27 0.338177
NOTCH2NL notch 2 N-terminal like 0.337808
PLD1 phospholipase D1, phosphatidylcholine-specific 0.3356
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.3356
NOTCH2 notch 2 0.334865
CALB1 calbindin 1, 28kDa 0.334865
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.33413
FTL ferritin, light polypeptide 0.333763
MORN1 MORN repeat containing 1 0.332294
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.332294
SPRED3 sprouty-related, EVH1 domain containing 3 0.330827
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.330827
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.330827
CD86 CD86 molecule 0.33046
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.329727
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.328994
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) 0.327896
MAPK9 mitogen-activated protein kinase 9 0.326798
TLR3 toll-like receptor 3 0.326432
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.326432
PLAGL1 pleiomorphic adenoma gene-like 1 0.326432
CCKAR cholecystokinin A receptor 0.326067
CXCL12 chemokine (C-X-C motif) ligand 12 0.324605
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.324605
STAT5B signal transducer and activator of transcription 5B 0.322779
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.320956
CD44 CD44 molecule (Indian blood group) 0.320591
PTHLH parathyroid hormone-like hormone 0.320227
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.319134
NAGK N-acetylglucosamine kinase 0.318407
PTK7 protein tyrosine kinase 7 (inactive) 0.318042
HSH2D hematopoietic SH2 domain containing 0.318042
CGB7 chorionic gonadotropin, beta polypeptide 7 0.318042
PRLR prolactin receptor 0.316224
ZADH2 zinc binding alcohol dehydrogenase domain containing 2 0.315498
CGB5 chorionic gonadotropin, beta polypeptide 5 0.314772
RAB3C RAB3C, member RAS oncogene family 0.314046
MDH1 malate dehydrogenase 1, NAD (soluble) 0.313683
FMNL3 formin-like 3 0.31332
UFM1 ubiquitin-fold modifier 1 0.312957
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14 0.312595
RFX7 regulatory factor X, 7 0.31187
SELL selectin L 0.310421
NELFCD negative elongation factor complex member C/D 0.308251
AOC3 amine oxidase, copper containing 3 0.307528
FADD Fas (TNFRSF6)-associated via death domain 0.306805
FKBP1A FK506 binding protein 1A, 12kDa 0.306444
RPH3AL rabphilin 3A-like (without C2 domains) 0.306083
FOXA3 forkhead box A3 0.305722
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 0.303919
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.303919
SYT4 synaptotagmin IV 0.303919
APOC3 apolipoprotein C-III 0.302478
CD80 CD80 molecule 0.302118
TTR transthyretin 0.301398
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.30032
CGB chorionic gonadotropin, beta polypeptide 0.299242
CGB8 chorionic gonadotropin, beta polypeptide 8 0.298165
SPATA21 spermatogenesis associated 21 0.297806
GH1 growth hormone 1 0.29673
DDRGK1 DDRGK domain containing 1 0.295655
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.295297
LMX1A LIM homeobox transcription factor 1, alpha 0.294581
SFXN5 sideroflexin 5 0.293508
PPP6C protein phosphatase 6, catalytic subunit 0.292793
PNPLA2 patatin-like phospholipase domain containing 2 0.291365
NFIB nuclear factor I/B 0.290295
SLC30A4 solute carrier family 30 (zinc transporter), member 4 0.289939
PLRG1 pleiotropic regulator 1 0.289226
MET MET proto-oncogene, receptor tyrosine kinase 0.288514
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.288514
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.288158
FGF2 fibroblast growth factor 2 (basic) 0.288158
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.287803
FGF21 fibroblast growth factor 21 0.286381
SYT12 synaptotagmin XII 0.286026
PTTG1 pituitary tumor-transforming 1 0.285671
MYO5A myosin VA (heavy chain 12, myoxin) 0.285316
NKX6-2 NK6 homeobox 2 0.284253
VGF VGF nerve growth factor inducible 0.283899
NFIA nuclear factor I/A 0.283899
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.283899
EXOC3 exocyst complex component 3 0.283545
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.283191
NOTCH1 notch 1 0.283191
CD5 CD5 molecule 0.282837
ALPPL2 alkaline phosphatase, placental-like 2 0.282483
SYCN syncollin 0.282483
ALPL alkaline phosphatase, liver/bone/kidney 0.281776
AVP arginine vasopressin 0.281423
ALPP alkaline phosphatase, placental 0.28107
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.280717
CBLN3 cerebellin 3 precursor 0.280364
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.280012
EGR1 early growth response 1 0.279307
CALR calreticulin 0.279307
HIST1H4I histone cluster 1, H4i 0.2779
HIST2H4A histone cluster 2, H4a 0.2779
HIST2H4B histone cluster 2, H4b 0.2779
HIST1H4H histone cluster 1, H4h 0.2779
HIST1H4D histone cluster 1, H4d 0.2779
HIST1H4F histone cluster 1, H4f 0.2779
HIST1H4B histone cluster 1, H4b 0.2779
HIST1H4A histone cluster 1, H4a 0.2779
HIST1H4E histone cluster 1, H4e 0.2779
HIST1H4K histone cluster 1, H4k 0.2779
HIST1H4J histone cluster 1, H4j 0.2779
HIST1H4C histone cluster 1, H4c 0.2779
GSR glutathione reductase 0.277197
HIST1H4L histone cluster 1, H4l 0.276846
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.276846
OMA1 OMA1 zinc metallopeptidase 0.276495
HIST4H4 histone cluster 4, H4 0.276495
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.275794
HMGA2 high mobility group AT-hook 2 0.275444
TP53 tumor protein p53 0.273696
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.272649
CTH cystathionine gamma-lyase 0.271952
EXOC2 exocyst complex component 2 0.271952
FEM1B fem-1 homolog b (C. elegans) 0.271604
TH tyrosine hydroxylase 0.271256
SSTR4 somatostatin receptor 4 0.270561
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.270561
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.269521
TM7SF3 transmembrane 7 superfamily member 3 0.266069
CCKBR cholecystokinin B receptor 0.266069
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.265381
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.265038
NOS1 nitric oxide synthase 1 (neuronal) 0.264696
CRTC2 CREB regulated transcription coactivator 2 0.264696
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.263669
PAM peptidylglycine alpha-amidating monooxygenase 0.262986
KIF7 kinesin family member 7 0.261284
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.260945
CDKN2A cyclin-dependent kinase inhibitor 2A 0.260945
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.260945
GRID2IP glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 0.260267
ADCY8 adenylate cyclase 8 (brain) 0.259591
SOX2 SRY (sex determining region Y)-box 2 0.258917
CREB3L1 cAMP responsive element binding protein 3-like 1 0.258243
MLX MLX, MAX dimerization protein 0.258243
SNED1 sushi, nidogen and EGF-like domains 1 0.257572
NRK Nik related kinase 0.256234
HTT huntingtin 0.256234
ESR2 estrogen receptor 2 (ER beta) 0.2559
SHH sonic hedgehog 0.2559
EXOC3L2 exocyst complex component 3-like 2 0.255234
ARRB1 arrestin, beta 1 0.25457
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.25457
NMUR1 neuromedin U receptor 1 0.25259
STK11 serine/threonine kinase 11 0.250953
PPCS phosphopantothenoylcysteine synthetase 0.250953
KIRREL2 kin of IRRE like 2 (Drosophila) 0.250301
PDZD2 PDZ domain containing 2 0.250301
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.249006
RPE65 retinal pigment epithelium-specific protein 65kDa 0.249006
DAAM2 dishevelled associated activator of morphogenesis 2 0.248361
HES1 hes family bHLH transcription factor 1 0.24804
LPL lipoprotein lipase 0.247719
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.247079
GLS2 glutaminase 2 (liver, mitochondrial) 0.247079
IL2RG interleukin 2 receptor, gamma 0.24676
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.245491
TMEM30C transmembrane protein 30C 0.245491
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 0.245491
SPTA1 spectrin, alpha, erythrocytic 1 0.245491
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 0.245175
REEP2 receptor accessory protein 2 0.243605
DIABLO diablo, IAP-binding mitochondrial protein 0.242672
EIF2A eukaryotic translation initiation factor 2A, 65kDa 0.24052
RNLS renalase, FAD-dependent amine oxidase 0.23961
CALCR calcitonin receptor 0.238706
CXCL9 chemokine (C-X-C motif) ligand 9 0.238406
MTMR9 myotubularin related protein 9 0.23781
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.237513
SMAD3 SMAD family member 3 0.237216
SGPP1 sphingosine-1-phosphate phosphatase 1 0.236921
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.236627
PRSS21 protease, serine, 21 (testisin) 0.236627
TMEM184A transmembrane protein 184A 0.236332
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.235748
CABIN1 calcineurin binding protein 1 0.235457
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.235457
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.235457
NMUR2 neuromedin U receptor 2 0.235167
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 0.235167
GPR83 G protein-coupled receptor 83 0.234302
EP300 E1A binding protein p300 0.233446
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.233162
ADCY5 adenylate cyclase 5 0.233162
TLE2 transducin-like enhancer of split 2 0.232599
CARTPT CART prepropeptide 0.232317
SFXN2 sideroflexin 2 0.232039
IGF2-AS IGF2 antisense RNA 0.23176
APOB apolipoprotein B 0.23176
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) 0.23176
TAC1 tachykinin, precursor 1 0.231206
KCNK16 potassium channel, two pore domain subfamily K, member 16 0.230931
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.230656
TFAM transcription factor A, mitochondrial 0.230382
RBM47 RNA binding motif protein 47 0.23011
SPAG9 sperm associated antigen 9 0.228764
FADS1 fatty acid desaturase 1 0.227445
EXOC5 exocyst complex component 5 0.227445
JUND jun D proto-oncogene 0.227186
CBLN4 cerebellin 4 precursor 0.227186
FGD1 FYVE, RhoGEF and PH domain containing 1 0.226411
TSPO translocator protein (18kDa) 0.226411
GPR75 G protein-coupled receptor 75 0.225144
ONECUT2 one cut homeobox 2 0.224893
FGF7 fibroblast growth factor 7 0.224645
KHK ketohexokinase (fructokinase) 0.22246
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.221521
NANOG Nanog homeobox 0.221291
WDR5 WD repeat domain 5 0.221061
CD48 CD48 molecule 0.220152
GHR growth hormone receptor 0.219928
PROK1 prokineticin 1 0.219707
CLECL1 C-type lectin-like 1 0.219707
ETNPPL ethanolamine-phosphate phospho-lyase 0.217974
NPY4R neuropeptide Y receptor Y4 0.217762
BGLAP bone gamma-carboxyglutamate (gla) protein 0.217554
APOE apolipoprotein E 0.217346
FGF4 fibroblast growth factor 4 0.217139
SFXN3 sideroflexin 3 0.217139
RPS15 ribosomal protein S15 0.21673
GPR84 G protein-coupled receptor 84 0.21673
BCAM basal cell adhesion molecule (Lutheran blood group) 0.21673
SP1 Sp1 transcription factor 0.215534
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.215147
GLI1 GLI family zinc finger 1 0.214954
CCL4 chemokine (C-C motif) ligand 4 0.214765
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.214202
ASXL3 additional sex combs like transcriptional regulator 3 0.213833
ACE2 angiotensin I converting enzyme 2 0.212936
CCL3 chemokine (C-C motif) ligand 3 0.212586
SPHK1 sphingosine kinase 1 0.183008
SCTR secretin receptor 0.182103
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.181797
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.181531
SPHK2 sphingosine kinase 2 0.181051
NTSR2 neurotensin receptor 2 0.180518
NMB neuromedin B 0.178448
ACACB acetyl-CoA carboxylase beta 0.171805
SCG3 secretogranin III 0.170049
RIMS1 regulating synaptic membrane exocytosis 1 0.168627
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.167814
GPR27 G protein-coupled receptor 27 0.167122
STX3 syntaxin 3 0.167046
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.163496
NPY2R neuropeptide Y receptor Y2 0.163303
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.162141
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 0.161753
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.160992
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 0.159923
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 0.158311
CDK11A cyclin-dependent kinase 11A 0.156922
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.154834
MFN1 mitofusin 1 0.152137
DDT D-dopachrome tautomerase 0.151416
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.150421
RUNDC3A RUN domain containing 3A 0.149668
BAD BCL2-associated agonist of cell death 0.148925
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.148674
GAN gigaxonin 0.148606
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.148332
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.146886
DNM1L dynamin 1-like 0.146839
APOA5 apolipoprotein A-V 0.1466
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.145732
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 0.145369
WDR13 WD repeat domain 13 0.144427
NLRP3 NLR family, pyrin domain containing 3 0.144056
MGLL monoglyceride lipase 0.140206
DUX4L9 double homeobox 4 like 9 0.139697
DUX4L4 double homeobox 4 like 4 0.139697
NALCN sodium leak channel, non selective 0.134474
MAP3K9 mitogen-activated protein kinase kinase kinase 9 0.133296
HDAC3 histone deacetylase 3 0.13164
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.130872
CLSTN3 calsyntenin 3 0.129668
GJC1 gap junction protein, gamma 1, 45kDa 0.129417
REM2 RAS (RAD and GEM)-like GTP binding 2 0.128978
BRSK1 BR serine/threonine kinase 1 0.128321
METTL3 methyltransferase like 3 0.127362
GRM5 glutamate receptor, metabotropic 5 0.126755
PCSK9 proprotein convertase subtilisin/kexin type 9 0.125978
STX2 syntaxin 2 0.125132
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) 0.123018
TAGAP T-cell activation RhoGTPase activating protein 0.122818
GLP2R glucagon-like peptide 2 receptor 0.122683
KLF7 Kruppel-like factor 7 (ubiquitous) 0.122278
SI sucrase-isomaltase (alpha-glucosidase) 0.122211
SPO11 SPO11 meiotic protein covalently bound to DSB 0.121435
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 0.121267
ANXA11 annexin A11 0.120791
RAP2A RAP2A, member of RAS oncogene family 0.12014
SAG S-antigen; retina and pineal gland (arrestin) 0.119043
ADRB1 adrenoceptor beta 1 0.118659
ELSPBP1 epididymal sperm binding protein 1 0.118346
TIPRL TOR signaling pathway regulator 0.118311
HOXA6 homeobox A6 0.118032
SYTL2 synaptotagmin-like 2 0.117684
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.117163
CTSB cathepsin B 0.11635
CLSTN1 calsyntenin 1 0.116138
GRM8 glutamate receptor, metabotropic 8 0.115961
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.115005
DUX4L8 double homeobox 4 like 8 0.11479
MOCS2 molybdenum cofactor synthesis 2 0.114181
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.113466
HCRTR1 hypocretin (orexin) receptor 1 0.113106
PLD2 phospholipase D2 0.113106
ARF6 ADP-ribosylation factor 6 0.112961
HDAC1 histone deacetylase 1 0.112525
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.112453
MIR107 microRNA 107 0.112344
TCF12 transcription factor 12 0.111764
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.111547
NRG4 neuregulin 4 0.111037
ALG10 ALG10, alpha-1,2-glucosyltransferase 0.109715
STK3 serine/threonine kinase 3 0.109642
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.109569
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 0.109385
GPM6A glycoprotein M6A 0.10872
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.1082
HEXA hexosaminidase A (alpha polypeptide) 0.108051
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.108014
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 0.107792
UTS2 urotensin 2 0.106862
ADRB2 adrenoceptor beta 2, surface 0.10675
HOXC10 homeobox C10 0.106187
BLK BLK proto-oncogene, Src family tyrosine kinase 0.105625
SIRT3 sirtuin 3 0.105438
FRY furry homolog (Drosophila) 0.105288
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.105064
AANAT aralkylamine N-acetyltransferase 0.10442
NRD1 nardilysin (N-arginine dibasic convertase) 0.104344
STK26 serine/threonine protein kinase 26 0.104307
NRGN neurogranin (protein kinase C substrate, RC3) 0.104117
GRB2 growth factor receptor-bound protein 2 0.103928
RAP2B RAP2B, member of RAS oncogene family 0.103475
RAB1B RAB1B, member RAS oncogene family 0.103399
SAR1A secretion associated, Ras related GTPase 1A 0.103135
DAGLA diacylglycerol lipase, alpha 0.103059
ARF3 ADP-ribosylation factor 3 0.102984
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 0.10287
SYT2 synaptotagmin II 0.102564
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.102488
SLC16A4 solute carrier family 16, member 4 0.102335
GSK3A glycogen synthase kinase 3 alpha 0.102297
CST1 cystatin SN 0.102106
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.101344
PITX1 paired-like homeodomain 1 0.100234
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 0.10008
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.099465
MANBA mannosidase, beta A, lysosomal 0.099465
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.099082
UCN urocortin 0.099005
PCSK7 proprotein convertase subtilisin/kexin type 7 0.09866
ACPT acid phosphatase, testicular 0.098505
HOXC9 homeobox C9 0.098041
DNPEP aspartyl aminopeptidase 0.097963
AATF apoptosis antagonizing transcription factor 0.097963
ALOX12 arachidonate 12-lipoxygenase 0.097809
PFKP phosphofructokinase, platelet 0.097422
TLE3 transducin-like enhancer of split 3 0.097306
MAP2K3 mitogen-activated protein kinase kinase 3 0.097268
ACVR1B activin A receptor, type IB 0.097152
IRX2 iroquois homeobox 2 0.09692
AMPD2 adenosine monophosphate deaminase 2 0.096766
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.09599
RAB40AL RAB40A, member RAS oncogene family-like 0.095329
ACACA acetyl-CoA carboxylase alpha 0.09529
HDAC9 histone deacetylase 9 0.09529
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.094436
SV2B synaptic vesicle glycoprotein 2B 0.094359
GSX1 GS homeobox 1 0.09432
AHR aryl hydrocarbon receptor 0.093968
CDX4 caudal type homeobox 4 0.093929
SEPT5 septin 5 0.093851
ADRA2C adrenoceptor alpha 2C 0.093851
IRX1 iroquois homeobox 1 0.093304
EMC10 ER membrane protein complex subunit 10 0.093187
CPN1 carboxypeptidase N, polypeptide 1 0.09307
OXR1 oxidation resistance 1 0.09307
CNTN5 contactin 5 0.092953
DEAF1 DEAF1 transcription factor 0.092836
ATG5 autophagy related 5 0.092602
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 0.092602
IGLV3-21 immunoglobulin lambda variable 3-21 0.092524
DYNLT3 dynein, light chain, Tctex-type 3 0.092485
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.092407
DISP2 dispatched homolog 2 (Drosophila) 0.092369
HSPA14 heat shock 70kDa protein 14 0.09233
MIR27B microRNA 27b 0.092213
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 0.092095
JMJD6 jumonji domain containing 6 0.091977
ZC3H11A zinc finger CCCH-type containing 11A 0.091899
SUN3 Sad1 and UNC84 domain containing 3 0.091507
ARFIP1 ADP-ribosylation factor interacting protein 1 0.091507
GRM4 glutamate receptor, metabotropic 4 0.091429
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.091311
IFNL2 interferon, lambda 2 0.091233
MDK midkine (neurite growth-promoting factor 2) 0.091155
AK6 adenylate kinase 6 0.090998
FEM1C fem-1 homolog c (C. elegans) 0.090998
MSH4 mutS homolog 4 0.090881
STC2 stanniocalcin 2 0.090841
ATP10D ATPase, class V, type 10D 0.090802
HMG20A high mobility group 20A 0.090763
SPRY4 sprouty homolog 4 (Drosophila) 0.090685
STX6 syntaxin 6 0.090411
NOVA1 neuro-oncological ventral antigen 1 0.090372
HIPK3 homeodomain interacting protein kinase 3 0.090294
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.090216
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 0.090099
ARAF A-Raf proto-oncogene, serine/threonine kinase 0.090099
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.089903
ASS1 argininosuccinate synthase 1 0.089745
TGOLN2 trans-golgi network protein 2 0.089509
TLE4 transducin-like enhancer of split 4 0.089235
CDC7 cell division cycle 7 0.089156
ATF2 activating transcription factor 2 0.089078
CARD17 caspase recruitment domain family, member 17 0.088921
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.088568
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.088489
MARK2 MAP/microtubule affinity-regulating kinase 2 0.088489
SSR4 signal sequence receptor, delta 0.088411
SPATA2 spermatogenesis associated 2 0.088372
SCARB1 scavenger receptor class B, member 1 0.088372
HOXB6 homeobox B6 0.088372
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.088372
HAP1 huntingtin-associated protein 1 0.088372
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 0.087862
DMXL2 Dmx-like 2 0.087862
RAB2A RAB2A, member RAS oncogene family 0.087744
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.087666
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 0.087626
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.087429
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.087311