pancreatic ductal carcinoma cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Carcinoma that arises from the pancreatic ducts. It accounts for the majority of cancers derived from the pancreas. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002363)
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Genes

294 proteins co-occuring with the tissue pancreatic ductal carcinoma cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.63206
BRCA2 breast cancer 2, early onset 1.52664
SMAD4 SMAD family member 4 1.44682
RAD51 RAD51 recombinase 1.33093
KRAS Kirsten rat sarcoma viral oncogene homolog 1.2904
PEX6 peroxisomal biogenesis factor 6 1.27247
MUC4 mucin 4, cell surface associated 1.25726
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.24074
MUC1 mucin 1, cell surface associated 1.20734
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1 1.07
ZNF462 zinc finger protein 462 1.05325
HRAS Harvey rat sarcoma viral oncogene homolog 1.04752
NLRP2 NLR family, pyrin domain containing 2 0.993684
CLCA2 chloride channel accessory 2 0.992379
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 0.971552
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.916069
CLCA1 chloride channel accessory 1 0.904553
CLCA4 chloride channel accessory 4 0.887133
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.825686
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.820666
USP11 ubiquitin specific peptidase 11 0.811473
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.807716
VAMP5 vesicle-associated membrane protein 5 0.798958
MSLN mesothelin 0.782725
SPINK1 serine peptidase inhibitor, Kazal type 1 0.78231
KCNT2 potassium channel, sodium activated subfamily T, member 2 0.772759
PRSS1 protease, serine, 1 (trypsin 1) 0.769027
ZG16B zymogen granule protein 16B 0.750405
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.747102
BRCA1 breast cancer 1, early onset 0.726507
EGFR epidermal growth factor receptor 0.721577
FANCG Fanconi anemia, complementation group G 0.716241
DYM dymeclin 0.712549
KCNT1 potassium channel, sodium activated subfamily T, member 1 0.7105
TP53 tumor protein p53 0.699035
NEK9 NIMA-related kinase 9 0.695763
PARP1 poly (ADP-ribose) polymerase 1 0.682287
TGFBR1 transforming growth factor, beta receptor 1 0.681471
TGFB1 transforming growth factor, beta 1 0.674543
RAD51C RAD51 paralog C 0.674135
WSB1 WD repeat and SOCS box containing 1 0.666809
PFDN5 prefoldin subunit 5 0.6461
PROM1 prominin 1 0.642048
FANCC Fanconi anemia, complementation group C 0.641643
MPZL2 myelin protein zero-like 2 0.631931
ANO1 anoctamin 1, calcium activated chloride channel 0.630314
SMAD2 SMAD family member 2 0.626677
CDKN2A cyclin-dependent kinase inhibitor 2A 0.620621
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.610541
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.60893
GRP gastrin-releasing peptide 0.607319
NEK6 NIMA-related kinase 6 0.603697
TMPRSS15 transmembrane protease, serine 15 0.598469
CD24 CD24 molecule 0.598067
NTS neurotensin 0.580017
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.579216
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.566428
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.565232
CA2 carbonic anhydrase II 0.562042
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.561644
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.557661
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.545342
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.542566
LGALS1 lectin, galactoside-binding, soluble, 1 0.533065
KCNK5 potassium channel, two pore domain subfamily K, member 5 0.53267
CBX7 chromobox homolog 7 0.527928
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5 0.527928
SHH sonic hedgehog 0.527534
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 0.52635
ADAM9 ADAM metallopeptidase domain 9 0.52635
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.525166
BAX BCL2-associated X protein 0.522405
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 0.51453
DCK deoxycytidine kinase 0.51453
CA4 carbonic anhydrase IV 0.51335
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.509027
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 0.508635
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.503926
CLDN4 claudin 4 0.502357
CCND1 cyclin D1 0.500007
FANCD2 Fanconi anemia, complementation group D2 0.499223
BCL2L1 BCL2-like 1 0.498832
GLI1 GLI family zinc finger 1 0.491009
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.487106
NANS N-acetylneuraminic acid synthase 0.483986
C1GALT1C1 C1GALT1-specific chaperone 1 0.481259
ANXA5 annexin A5 0.48087
PSCA prostate stem cell antigen 0.48048
ZCCHC7 zinc finger, CCHC domain containing 7 0.479702
ERBB2 erb-b2 receptor tyrosine kinase 2 0.475812
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.474258
LSM1 LSM1, U6 small nuclear RNA associated 0.472704
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.459145
KRT18 keratin 18, type I 0.454126
CD44 CD44 molecule (Indian blood group) 0.445268
NDRG1 N-myc downstream regulated 1 0.443347
MMP9 matrix metallopeptidase 9 0.437972
SLC26A5 solute carrier family 26 (anion exchanger), member 5 0.430312
S100A8 S100 calcium binding protein A8 0.429165
PLCZ1 phospholipase C, zeta 1 0.426872
ADGRG1 adhesion G protein-coupled receptor G1 0.426872
CXCR4 chemokine (C-X-C motif) receptor 4 0.418861
MUC2 mucin 2, oligomeric mucus/gel-forming 0.418861
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.412771
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.411251
OCLN occludin 0.406315
S100A4 S100 calcium binding protein A4 0.401007
SON SON DNA binding protein 0.3976
SSTR5 somatostatin receptor 5 0.393819
RGS11 regulator of G-protein signaling 11 0.393819
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 0.391176
SMAD7 SMAD family member 7 0.381755
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.380627
PRKD1 protein kinase D1 0.380627
GRPR gastrin-releasing peptide receptor 0.378748
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.374243
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.373868
REV1 REV1, polymerase (DNA directed) 0.373493
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.373118
TYMS thymidylate synthetase 0.372369
INSIG2 insulin induced gene 2 0.367502
MIR10A microRNA 10a 0.363766
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.363393
OGFR opioid growth factor receptor 0.358919
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.35334
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.348148
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 0.344449
IL6ST interleukin 6 signal transducer 0.344079
COL14A1 collagen, type XIV, alpha 1 0.341495
OLFM4 olfactomedin 4 0.33744
CYTIP cytohesin 1 interacting protein 0.337072
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.33413
SST somatostatin 0.333396
L1CAM L1 cell adhesion molecule 0.331194
MGMT O-6-methylguanine-DNA methyltransferase 0.330094
LAMP2 lysosomal-associated membrane protein 2 0.326067
FN1 fibronectin 1 0.325335
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) 0.319863
PPAN-P2RY11 PPAN-P2RY11 readthrough 0.319134
P2RY11 purinergic receptor P2Y, G-protein coupled, 11 0.319134
MVD mevalonate (diphospho) decarboxylase 0.318407
EPS8 epidermal growth factor receptor pathway substrate 8 0.318042
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 0.317679
ZEB1 zinc finger E-box binding homeobox 1 0.31332
NMBR neuromedin B receptor 0.311507
EFNA3 ephrin-A3 0.309335
SMAD3 SMAD family member 3 0.30464
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.303559
MRPS7 mitochondrial ribosomal protein S7 0.302478
HHIP hedgehog interacting protein 0.298524
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.297089
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.291365
EXO1 exonuclease 1 0.287092
SIM2 single-minded family bHLH transcription factor 2 0.282483
BRS3 bombesin-like receptor 3 0.281776
EPCAM epithelial cell adhesion molecule 0.276846
SMO smoothened, frizzled class receptor 0.271604
MIR10B microRNA 10b 0.269521
HDGF hepatoma-derived growth factor 0.266069
IGHV3-30 immunoglobulin heavy variable 3-30 0.263327
HOXA3 homeobox A3 0.256234
SCGB1D1 secretoglobin, family 1D, member 1 0.255567
ADAM8 ADAM metallopeptidase domain 8 0.253578
DEK DEK proto-oncogene 0.251934
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.249329
SLC26A6 solute carrier family 26 (anion exchanger), member 6 0.24676
SKI SKI proto-oncogene 0.242983
SSTR2 somatostatin receptor 2 0.242054
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.242054
USP9X ubiquitin specific peptidase 9, X-linked 0.241438
PLAU plasminogen activator, urokinase 0.237513
PTCH1 patched 1 0.237216
UCK2 uridine-cytidine kinase 2 0.236921
CCNG1 cyclin G1 0.234302
KRT7 keratin 7, type II 0.234016
SIM1 single-minded family bHLH transcription factor 1 0.23176
S100A11 S100 calcium binding protein A11 0.230656
MMP2 matrix metallopeptidase 2 0.228764
ATR ATR serine/threonine kinase 0.227186
RAP1B RAP1B, member of RAS oncogene family 0.226926
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.225395
MEGF6 multiple EGF-like-domains 6 0.222938
FGFR1 fibroblast growth factor receptor 1 0.221989
VEGFA vascular endothelial growth factor A 0.218613
AGR2 anterior gradient 2 0.216933
RAD52 RAD52 homolog (S. cerevisiae) 0.216325
ACVR1 activin A receptor, type I 0.214765
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.214576
TMSB10 thymosin beta 10 0.212761
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.193024
SYCN syncollin 0.192609
CCNE1 cyclin E1 0.192272
CDX1 caudal type homeobox 1 0.191156
HAVCR1 hepatitis A virus cellular receptor 1 0.190825
BGN biglycan 0.18515
KIF11 kinesin family member 11 0.185141
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.184754
MIR210 microRNA 210 0.179189
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.178975
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.17827
SFRP4 secreted frizzled-related protein 4 0.177623
HOXB7 homeobox B7 0.177591
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.177207
SORT1 sortilin 1 0.177125
LDHAL6A lactate dehydrogenase A-like 6A 0.177027
S100A6 S100 calcium binding protein A6 0.172417
PCNA proliferating cell nuclear antigen 0.171566
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.171542
SDC4 syndecan 4 0.17001
NGF nerve growth factor (beta polypeptide) 0.168958
LDHB lactate dehydrogenase B 0.168906
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.167599
SPP1 secreted phosphoprotein 1 0.164692
LMAN1 lectin, mannose-binding, 1 0.164308
BEST1 bestrophin 1 0.164078
MST1 macrophage stimulating 1 0.164078
ENO1 enolase 1, (alpha) 0.163618
RORC RAR-related orphan receptor C 0.161389
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.161027
RAD50 RAD50 homolog (S. cerevisiae) 0.160653
PAX4 paired box 4 0.15936
CHPF chondroitin polymerizing factor 0.159047
UGT8 UDP glycosyltransferase 8 0.158888
MIR191 microRNA 191 0.158609
STK11 serine/threonine kinase 11 0.15638
S100G S100 calcium binding protein G 0.156211
LDHA lactate dehydrogenase A 0.154984
CHEK1 checkpoint kinase 1 0.154713
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.154443
FRZB frizzled-related protein 0.153111
EPHB2 EPH receptor B2 0.152925
MIR146A microRNA 146a 0.152495
IL2RG interleukin 2 receptor, gamma 0.152256
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.152113
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.151779
FOXP2 forkhead box P2 0.15173
FASN fatty acid synthase 0.151385
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.150295
NEUROG3 neurogenin 3 0.150193
COL6A1 collagen, type VI, alpha 1 0.150143
SDC2 syndecan 2 0.149383
FOXM1 forkhead box M1 0.148082
MAP2K3 mitogen-activated protein kinase kinase 3 0.146741
DUOX2 dual oxidase 2 0.146631
RPE65 retinal pigment epithelium-specific protein 65kDa 0.146355
GLI2 GLI family zinc finger 2 0.146189
HDAC3 histone deacetylase 3 0.144795
MUC16 mucin 16, cell surface associated 0.144738
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.144569
FADD Fas (TNFRSF6)-associated via death domain 0.144342
ATF6 activating transcription factor 6 0.144229
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.144116
GLI3 GLI family zinc finger 3 0.144116
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.144002
CLDN3 claudin 3 0.143943
CDX2 caudal type homeobox 2 0.143769
RRM2 ribonucleotide reductase M2 0.143013
GSN gelsolin 0.143013
SREBF1 sterol regulatory element binding transcription factor 1 0.142723
CIITA class II, major histocompatibility complex, transactivator 0.142723
PXN paxillin 0.142665
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.142188
TYMP thymidine phosphorylase 0.141591
TPI1 triosephosphate isomerase 1 0.141591
FXYD5 FXYD domain containing ion transport regulator 5 0.141234
ACVR2A activin A receptor, type IIA 0.141112
E2F3 E2F transcription factor 3 0.141051
RNASEH2A ribonuclease H2, subunit A 0.1405
GLP1R glucagon-like peptide 1 receptor 0.140439
SFRP1 secreted frizzled-related protein 1 0.140317
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.140072
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.139889
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.139889
ACVR1B activin A receptor, type IB 0.139767
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.139203
CDSN corneodesmosin 0.138827
PIGR polymeric immunoglobulin receptor 0.138702
AQP8 aquaporin 8 0.138263
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.137687
LIG1 ligase I, DNA, ATP-dependent 0.137558
TFG TRK-fused gene 0.137494
MDK midkine (neurite growth-promoting factor 2) 0.13743
MNT MAX network transcriptional repressor 0.136788
TNF tumor necrosis factor 0.13666
S100A9 S100 calcium binding protein A9 0.135871
CDK6 cyclin-dependent kinase 6 0.135542
CXCL8 chemokine (C-X-C motif) ligand 8 0.135345
ADA adenosine deaminase 0.135017
ALOX12 arachidonate 12-lipoxygenase 0.134949
KAT5 K(lysine) acetyltransferase 5 0.134613
EGR3 early growth response 3 0.134478
PSAP prosaposin 0.134075
MNX1 motor neuron and pancreas homeobox 1 0.133739
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.133197