pancreatic adenocarcinoma Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A pancreatic carcinoma that derives_from epithelial cells of glandular origin. (Human Disease Ontology, DOID_4074)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0006725
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Genes

83 genes associated with the pancreatic adenocarcinoma phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
COL18A1 collagen, type XVIII, alpha 1 2.05815
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.61591
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 1.43716
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 1.43716
NR5A2 nuclear receptor subfamily 5, group A, member 2 1.41863
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 1.38847
IL17F interleukin 17F 1.19958
SBF2 SET binding factor 2 1.13417
BICD1 bicaudal D homolog 1 (Drosophila) 1.11203
CLPTM1L CLPTM1-like 1.10324
LDLRAD4 low density lipoprotein receptor class A domain containing 4 1.07729
DAPK1 death-associated protein kinase 1 1.04365
PRB2 proline-rich protein BstNI subfamily 2 1.04365
DEC1 deleted in esophageal cancer 1 1.00059
GRID1 glutamate receptor, ionotropic, delta 1 0.969142
RNF149 ring finger protein 149 0.942765
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.926083
LPIN2 lipin 2 0.901003
MYO1D myosin ID 0.899912
BCAR1 breast cancer anti-estrogen resistance 1 0.888782
SMTN smoothelin 0.884439
PARK2 parkin RBR E3 ubiquitin protein ligase 0.882984
DGKH diacylglycerol kinase, eta 0.871984
RNF43 ring finger protein 43 0.868241
DCP1B decapping mRNA 1B 0.868241
CAMK4 calcium/calmodulin-dependent protein kinase IV 0.866096
HNF1A HNF1 homeobox A 0.860885
PVT1 Pvt1 oncogene (non-protein coding) 0.859619
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa 0.855449
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.850223
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 0.82221
ERO1LB ERO1-like beta (S. cerevisiae) 0.820614
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.724872
WWOX WW domain containing oxidoreductase 0.720196
ANKRD12 ankyrin repeat domain 12 0.717203
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) 0.715742
SUGCT succinyl-CoA:glutarate-CoA transferase 0.703184
IMPG2 interphotoreceptor matrix proteoglycan 2 0.693105
SGMS1 sphingomyelin synthase 1 0.685732
FAM149A family with sequence similarity 149, member A 0.684849
SYNDIG1 synapse differentiation inducing 1 0.681396
RUNX2 runt-related transcription factor 2 0.676616
SIM1 single-minded family bHLH transcription factor 1 0.675718
MGST2 microsomal glutathione S-transferase 2 0.674238
ASTN2 astrotactin 2 0.664175
POC1B POC1 centriolar protein B 0.654304
NXPH1 neurexophilin 1 0.651688
L3MBTL4 l(3)mbt-like 4 (Drosophila) 0.640092
EMILIN2 elastin microfibril interfacer 2 0.638465
AVEN apoptosis, caspase activation inhibitor 0.634172
KIAA1217 KIAA1217 0.628153
HNF4G hepatocyte nuclear factor 4, gamma 0.605862
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.603282
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.598959
CAB39L calcium binding protein 39-like 0.595757
UBASH3B ubiquitin associated and SH3 domain containing B 0.592807
TP63 tumor protein p63 0.588613
EML6 echinoderm microtubule associated protein like 6 0.588467
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.58318
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 0.580796
FNBP1L formin binding protein 1-like 0.577677
SMOC1 SPARC related modular calcium binding 1 0.573902
LPAR1 lysophosphatidic acid receptor 1 0.573577
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.559371
ZNF831 zinc finger protein 831 0.55536
APTX aprataxin 0.546854
TMEM213 transmembrane protein 213 0.545725
CTIF CBP80/20-dependent translation initiation factor 0.544615
PRKCA protein kinase C, alpha 0.541144
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 0.541144
ATP13A4 ATPase type 13A4 0.536325
MEF2BNB MEF2B neighbor 0.53334
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.523869
IGSF21 immunoglobin superfamily, member 21 0.522136
SLC22A18 solute carrier family 22, member 18 0.522136
NRG3 neuregulin 3 0.498792
DSCAM Down syndrome cell adhesion molecule 0.498792
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.498792
IQSEC1 IQ motif and Sec7 domain 1 0.498792
ACSM1 acyl-CoA synthetase medium-chain family member 1 0.466578
DFNB31 deafness, autosomal recessive 31 0.466578
KCNK10 potassium channel, two pore domain subfamily K, member 10 0.443881
LIN7C lin-7 homolog C (C. elegans) 0.435659